Catalogo dei Corsi di studio

CURRICULUM VITAE
Gianni Prosseda
Latina (Italy) 07/03/ 1968
Sapienza University of Rome
Dept of Biology and Biotechnology C. Darwin
Via dei Sardi 70
00185 Rome (Italy)
Email gianni.prosseda@uniroma1.it
ORCID: https://orcid.org/0000-0001-5235-0086

Positions and education

2022-2031: National Scientific Qualification cat Full Professor (05/I2-Microbiology)
Since 2019: Associate Professor of Microbiology (SSD/ BIO19), Dept. Biology and Biotechnologies C Darwin , Faculty of Sciences, Sapienza University of Rome
2002-2019: Researcher at the Dept. of Cell and Developmental Biology, Faculty of Sciences, Sapienza University of Rome
2001: Advanced School in Biotechnological Application (maximum honors), from the University of Rome "Sapienza .
2000: Ph.D. in Cellular and Developmental Biology, from the University of Rome "Sapienza .
1997: Master in Planning expert of quality assurance: food, packaging and chemical industry from IFOA, Camera del Commercio , Latina.
1994: Laurea in Biological Science (maximum honors), from the University of Rome "Sapienza .

Other appointments
Teaching
Since 2018: Professor of Microbiology for students in Bioinformatics at Sapienza University of Rome
In 2016: Professor of Applied Microbiology for the student in Sciences and Technologies for the Quality and Enhancement of Agri-food Products at Sapienza University of Rome
Since 2008: Professor of General Microbiology, Microbial Biotechnologies and Element of Medical Microbiology II for the student in Biotechnology at Sapienza University of Rome
From 2003 to 2007 Professor of General Microbiology and Microbial Biotechnologies for the student in Biotechnology at Sapienza University of Rome
September 2019: Invited teacher at the COURS DE MICROBIOLOGIE 2019-2020 at the Institut Pasteur (Paris, France)

Committee:
2020: Member of the Committee for the Qualifying examinations for Biologist, Sapienza University of Rome
In 2011, 2012, 2013, 2014, 2016, and 2018, President of the Committee for the admission to the degree course in Biotechnology, the Sapienza University of Rome for the years.
In 2015, a member of the Ph.D. Committee in Biology Applied to Human Health (BASU), Department of Sciences, University of Roma Tre
In 2014 Member of the Ph.D. Committee in Cellular and Molecular Biology at the Alma Mater Studiorum - University of Bologna
2011 Member of the Ph.D. Committee in Biology (XXIV Cycle), Roma Tre University.
2009: Member of the Ph.D. Committee in Public Health Sciences and Microbiology (XXI Cycle), Sapienza University of Rome Tre.
2008: Member of the Committee for a research position at the Faculty of Sciences M.F.N. of the University of Salento.

Editorial activity
Since 2018: Member of the editorial board of Frontiers in Cellular and Infection Microbiology
Since 2018: Member of the editorial board of Scientific Report
2003 and 2007: English to italian translator of the 10th, 11th and 13th edition of the textbook Brock: Biology of Microrganisms Prentice Hall.

Manuscript reviewing/referee activity
Plos ONE, Frontiers in Microbiology, FEMS Letters, Genes, BMC Microbiology, Frontiers in Cellular and Infection Microbiology, APMIS, OBMN Genetics, International Journal of Medical Microbiology, etc. .

Funded Scientific Projects (Last 5 years)

PI Sapienza s Team (partnership with Università di Modena) for the ERC Advanzed Grant Holo-GT (PI Prof. De Luca). (2021-2025)
Co-PI of the scientific project entitled Combination therapies for fighting antibiotic resistant bloodstream infections in cancer patients (EACT) funded by the Executive Program of Cooperation in the field of Science and Technology between the government of Italy and the government of Japan for the years 2021-2023 .
2021 PI of the Project Shigella virulence: a study of the influence of intestinal metabolites on the activation of the VirF protein , Middle Project from University.
PI of the Scientific Project FABBR 2017

Synopsis of current scientific activity

The research activity of Prof. Prosseda has always been focused on the study of the expression of virulence factors in pathogenic bacteria and on the relationship between this expression and the environmental stimuli on which they seem to depend. The model system is mainly represented by the pathogenic microorganism Shigella and pathogenic E. coli. Part of Dr. Prosseda's work also concerns the study of the genetic mechanisms of bacterial evolution towards pathogenicity. More recently, Dr. Prosseda has devoted himself to studying the influence of intestinal metabolites on the regulation of the virulence genes of enteropathogens. It is analyzing how molecules normally present in the human intestine can influence and, in some cases, direct and coordinate the expression of the virulence genes of these pathogens.

Documents by author: 37
Citations by 859 documents: 1289
h-index: 19

Scientific published papers (last three years 2019-21)

Pasqua M, Bonaccorsi di Patti MC, Fanelli G, Utsumi R, Eguchi Y, Trirocco R, Prosseda G, Grossi M, Colonna B. Host - Bacterial Pathogen Communication: The Wily Role of the Multidrug Efflux Pumps of the MFS Family Front Mol Biosci. 2021 Jul 26;8:723274. doi: 10.3389/fmolb.2021.723274. eCollection 2021. PMID: 34381818 Free PMC article. Review.
Pasqua M, Zennaro A, Trirocco R, Fanelli G, Micheli G, Grossi M, Colonna B, Prosseda G. Modulation of OMV Production by the Lysis Module of the DLP12 Defective Prophage of Escherichia coli K12. Microorganisms. 2021 Feb 12;9(2):369. doi: 10.3390/microorganisms9020369. PMID: 33673345 Free PMC article.
Fanelli G, Pasqua M, Colonna B, Prosseda G, Grossi M. Expression Profile of Multidrug Resistance Efflux Pumps During Intracellular Life of Adherent-Invasive Escherichia coli Strain LF82. Front Microbiol. 2020 Aug 17;11:1935. doi: 10.3389/fmicb.2020.01935. eCollection 2020. PMID: 33013734 Free PMC article.
Michelacci V, Tozzoli R, Arancia S, D'Angelo A, Boni A, Knijn A, Prosseda G, Greig DR, Jenkins C, Camou T, Sirok A, Navarro A, Schelotto F, Varela G, Morabito S. Tracing Back the Evolutionary Route of Enteroinvasive Escherichia coli (EIEC) and Shigella Through the Example of the Highly Pathogenic O96:H19 EIEC Clone. Front Cell Infect Microbiol. 2020 Jun 3;10:260. doi: 10.3389/fcimb.2020.00260. eCollection 2020. PMID: 32582565 Free PMC article.
Pasqua M, Grossi M, Zennaro A, Fanelli G, Micheli G, Barras F, Colonna B, Prosseda G. The Varied Role of Efflux Pumps of the MFS Family in the Interplay of Bacteria with Animal and Plant Cells. Microorganisms. 2019 Aug 22;7(9):285. doi: 10.3390/microorganisms7090285. PMID: 31443538 Free PMC article. Review.
Pasqua M, Grossi M, Scinicariello S, Aussel L, Barras F, Colonna B, Prosseda G. The MFS efflux pump EmrKY contributes to the survival of Shigella within macrophages Sci Rep. 2019 May 22;9(1):7912. doi: 10.1038/s41598-019-44357-2. PMID: 31113989 Free PMC article.
Pasqua M, Grossi M, Scinicariello S, Aussel L, Barras F, Colonna B, Prosseda G. The MFS efflux pump EmrKY contributes to the survival of Shigella within macrophages. Sci Rep. 2019 Feb 27;9(1):2906. doi: 10.1038/s41598-019-39749-3. PMID: 30814604 Free PMC article.