GIULIA DI STEFANO

Part I – General Information

Full Name Giulia Di Stefano
Permanent Address Department of Human Neuroscience. Viale Università 30, 00185, Rome
E-mail giulia.distefano@uniroma1.it

Part II – Education

University Graduation, 2008 Sapienza, University of Rome Thesis title: “Trigeminal neuropathic pain: “clinical, neurophysiological and skin biopsy study”. 110/110 cum Laude

Specialty 2014 Sapienza, University of Rome, Thesis title: “Painful polyneuropathy: neurophysiological and histological study”. 70/70 cum Laude

PhD 2019 Sapienza, University of Rome PhD Course: Tecnologie innovative nelle malattie della cute, dello scheletro e del distretto oro-cranio facciale. Thesis title: “Trigeminal Neuralgia: from clinical characteristics to pathophysiological mechanisms”. Giudizio: cum Laude.

Training Course 2016 Italian Association Peripheral Nervous System, Advanced Training Course on Peripheral Neuropathy – Small fiber neuropathies

Conseguimento della certificazione relativa al percorso formativo biennale sull’innovazione della didattica realizzato dal 22 settembre 2022 al 20 giugno 2024 nell’ambito del progetto formativo QuID per i docenti Sapienza.

Part III – Appointments

IIIA – Academic Appointments

Start End Institution Position

2025-ongoing Sapienza, University of Rome Associate Professor of Neurology, Department of Human Neuroscience
2022-2025 Sapienza, University of Rome Fixed term researcher, type B, Department of Human Neuroscience
2018-2022 Sapienza, University of Rome Fixed term researcher, type A, Department of Human Neuroscience
2016-2017 Sapienza, University of Rome Research Fellow
2013 2014 Department of Neuroscience, Physiology and Pharmacology, University College of London Research Fellowship in Neuroscience
2024-ongoing Sapienza, University of Rome Tutor of “VII edizione del Programma Sapienza per la valorizzazione della professione docente, rivolto a tutti i docenti di nuova nomina e curato dal Gruppo di lavoro per la Qualità e l’Innovazione della Didattica (QuID D.R. n.2334 del 18/09/2017)”.

Part IV – Teaching experience

Year Institution Lecture/Course
2022/2023 Sapienza, University of Rome Lecturer at the “Corso di Alta Formazione in Elettromiografia Clinica: Brainstem reflexes; Neurophysiological techniques in trigeminal neuropathies”
2020/2023 Sapienza, University of Rome “Scienze delle professioni sanitarie tecniche diagnostiche. Neurologia”
2020/2023 Sapienza, University of Rome “Tecniche di neurofisiopatologia. Fisiopatologia del dolore”
2020/2022 Sapienza, University of Rome “Tecniche di neurofisiopatologia
Fisiopatologia del coma e morte cerebrale”
2018/2023 Sapienza, University of Rome “Medicina e Chirurgia-Corso di Laurea B-Malattie del Sistema Nervoso”
2018/2023 Sapienza, University of Rome “Fisioterapia - Corso di laurea D - Roma Azienda S. Camillo Forlanini L/SNT2. Neurologia”
2018/2020 Sapienza, University of Rome “Infermieristica (abilitante alla professione sanitaria di Infermiere) ROMA - Corso di laurea I - I.F.O. L/SNT1. Neurologia”
2018/2020 Sapienza, University of Rome “Scienze riabilitative delle professioni sanitarie LM/SNT2. Scienze tecniche mediche applicate”
2017/2018 Sapienza, University of Rome “Terapia occupazionale – sede di Viterbo [L (DM 270/04). Neurologia”
2018 Sapienza, University of Rome Lecturer at the “Corso di Alta Formazione in Elettromiografia Clinica, Modulo 7: Neurofisiologia Neuropatie Craniche”
2013 Italian society of clinical neurophysiology Lecturer at the “XII Corso di Base in EMG e potenziali evocati (Sorrento, 16- 22 Marzo 2013)”
2015 Italian society of clinical neurophysiology Lecturer at the “XIV Corso Residenziale di Elettroencefalografia e Tecniche Correlate (Tirrenia, 14 Marzo 2015)”

Part V - Society memberberships, Awards and Honors

Year Title
Since 2024 Member of the Scientific Advisory Board for the Facial Pain Research Foundation
Since 2021 Vice president of “Associazione Italiana Dolore Oro-facciale (AIDOF)”
2018-2024 Coordinator of “neurophysiology of pain study group” of the Italian society of clinical neurophysiology
Since 2023 Member of the Neuropathic Pain Interest Group of the Italian Society of Neurology
Since 2024 Member of advisory board of European Journal of Pain
Since 2008 Member of the Italian society of clinical neurophysiology (SINC)
Since 2013 Member of the International Association for the study of Pain (IASP)
Since 2013 Member of the Neuropathic Pain (NeuPSIG), IASP Special Interest Groups
2024 The project “disclosing Trigeminal system damage in chronic Oro-facial Pain (TOP)” was selected as eligible in the context of Fondo Italiano per la Scienza (FIS) 2023 call.
2024 The work “Trigeminal reflex testing abnormalities as a predictive model for distinguishing classical and idiopathic trigeminal neuralgia” was selected as Editor’s choice, Clinical Neurophysiology, 2025
2024 Winner “Paladini Italiani della Salute 2024”. The paper “Familial trigeminal neuralgia” was selected for publication in “PALADINI ITALIANI DELLA SALUTE” volume.
2022 Winner of the “PhD Thesis Award 2020” Macroarea C. Thesis title: “Trigeminal Neuralgia: from clinical characteristics to pathophysiological mechanisms” (Sapienza Università Editrice)
2022 The research in the field of trigeminal neuralgia was selected among the ten finalists of the 2021 Prize by the scientific committee of the Aldo Fasolo Prize for communication in Neuroscience.
2021 Winner “Paladini Italiani della Salute 2021”. The paper “Diagnostic accuracy of laser-evoked potentials in diabetic neuropathy” was selected for publication in “PALADINI ITALIANI DELLA SALUTE” volume.
2019 Winner of the “Premio Minerva alla Ricerca Scientifica II Edizione, Vincitore Macroarea C (Fondazione Roma Sapienza)”
2011 EFNS Investigator Awards - EFNS Scientist Panel. Title of the study: “Clinical and neurophysiological study of neuropathic pain in patients with multiple sclerosis”
2017 NeuPSIG Financial Aid for the 7th International Congress on Neuropathic Pain
2017 EFIC Financial Aid for the 10th Congress of the European Pain Federation
2016 IASP Financial Aid for the 16th World Congress on Pain
2016 Winner of a bursary promoted by the AISNP (“Associazione Italiana Sistema Nervoso Periferico”) for attending the Advanced Training Course on Peripheral Neuropathy – Small fiber neuropathies
2015 Winner of EC-IFCN boursary (Ed. 2015) for the 15th European Congress of Clinical Neurophysiology (ECCN), with the following scientific contribution: “Pain-related cortex function in patients with Alzheimer disease”
2009 Best Scientific Contribution. XL Congresso SIN. “Topographical distribution of unmyelinated – fibres related receptors. Psychophysical study of thermal, nociceptive and itching perception”

Part VI - Funding Information

Grants as Principal Investigator

Year Title Program Grant value
2022 “Progetto Ateneo – Progetti piccoli”, Sapienza, University of Rome “Pain mechanisms in trigeminal neuralgia” 3.500,00€
2021 IASP Collaborative Research Grant “Disclosing pain mechanisms in trigeminal neuralgia” Collaborators: Stephen Waxman, Yale University School of Medicine; Francis O’Neill, University of Liverpool; Joanna Zakrzewska, UCLH NHS Foundation Trust; Stine Maarbjerg, University of Copenhagen 15.000,00$
2016 “Progetto Ateneo - Avvio alla ricerca”, Sapienza, University of Rome “The defensive peripersonal space in patients with trigeminal neuralgia” 2.000,00 €
2013 “Giuseppe Ayala” scholarship for reserch fellowship, Fondazione Roma Sapienza Research Fellowship in Neuroscience, University College of London 10.000,00 €

Part X– Full list of Publications

1. Coppola G, Arruda MA, Ashina M, Barloese M, Belin AC, Bottiroli S, Chowdhury D, De Icco R, Di Lorenzo C, Di Stefano G, Edvinsson JCA, Evers S, Ferraro S, Fronczek R, García-Azorín D, Goadsby PJ, Grazzi L, Holle D, Jansen JJ, Gil-Gouveia R, Lambru G, Lanteri-Minet M, Lisicki M, Mitsikostas DD, Monteith T, Montisano DA, Obermann M, Pan LH, Peng KP, Peres M, Petrušić I, Cecchini AP, Vila-Pueyo M, Raggi A, Rainero I, Sandrini G, Sebastianelli G, Takizawa T, Tanprawate S, Tassorelli C, Truini A, Valeriani M, Vuralli D, Waliszewska-Prosół M, Wang SJ, Wang Y, Wijeratne T, Martelletti P. Hallmarks of primary headache: part 3 - cluster headache. J Headache Pain. 2025 Oct 2;26(1):196.
2. Falco P, Galosi E, Leone CM, De Stefano G, Di Pietro G, Di Stefano G, Esposito N, Evangelisti E, Litewczuk D, Mollica C, Arendt-Nielsen L, Truini A. Comparative Analysis of Small Nerve Fiber Density in Fibromyalgia Syndrome and Small Fiber Neuropathy. Biomedicines. 2025 Aug 29;13(9):2109.
3. Devigili G, Di Stefano G, Donadio V, Frattale I, Grazzi L, Mantovani E, Nolano M, Provitera V, Quitadamo SG, Tamburin S, Truini A, Valeriani M, Furia A, Vecchio E, Fischetti F, Greco G, Telesca A, de Tommaso M; On behhalf of neuropathic pain special interest group of the Italian neurological society (sin). Therapeutic approach to fibromyalgia: a consensus statement on pharmacological and non-pharmacological treatment from the neuropathic pain special interest group of the Italian neurological society. Neurol Sci. 2025 May;46(5):2263-2288.
4. Caramia F, Di Renzo A, Fiorelli M, De Stefano G, Di Stefano G, Boccia M, Tullo MG, Cartocci G, Gianni C, Truini A. Structural alterations in occipital cortices in trigeminal neuralgia: a voxel- and surface-based morphometric MRI study. J Headache Pain. 2025 Jul 16;26(1):162.
5. Nardoni L, et al. Structural brain alterations and changes in resting-state functional connectivity in patients with trigeminal neuralgia: A meta-analysis. Neuroimage Clin. 2025.
6. Galosi E, Litewczuk D, De Stefano G, Di Pietro G, Di Stefano G, Esposito N, Evangelisti E, Falco P, Leone C, Sachau J, Baron R, Finnerup NB, Truini A. Diagnostic accuracy of quantitative sensory testing for detecting small fiber impairment in polyneuropathy and diagnosing small fiber neuropathy. Pain. 2025 Jun 19.
7. Joncas CT, Ma K, Tugend M, Washington E, Di Stefano G, Truini A, Sekula RF. Long Term Outcomes after Microvascular Decompression for Glossopharyngeal Neuralgia.
Jr.Neurosurg Focus. 2025 Sep 1;59(3):E19.
8. Ashina S, Robertson CE, Srikiatkhachorn A, Di Stefano G, Donnet A, Hodaie M, Obermann M, Romero-Reyes M, Park YS, Cruccu G, Bendtsen L. Trigeminal neuralgia. Nat Rev Dis Primers. 2024 May 30;10(1):39.
9. Coluzzi F, Di Stefano G, Scerpa MS, Rocco M, Di Nardo G, Innocenti A, Vittori A, Ferretti A, Truini A. The Challenge of Managing Neuropathic Pain in Children and Adolescents with Cancer. Cancers (Basel). 2025 Jan 29;17(3):460.
10. Galosi E, Falco P, Di Pietro G, Esposito N, De Stefano G, Evangelisti E, Leone C, Litewczuk D, Tramontana L, Di Stefano G, Truini A.
Epidermal Transient Receptor Potential Vanilloid 1 innervation is increased in patients with painful diabetic polyneuropathy experiencing ongoing burning pain. Pain. 2025 Apr 1;166(4):824-834.
11. De Stefano G, Mollica C, Leone C, Galosi E, Di Pietro G, Falco P Pietro, Esposito N, Litewczuk D, Evangelisti E, Caramia F, Truini A, Di Stefano G. Trigeminal reflex testing abnormalities as a predictive model for distinguishing classical and idiopathic trigeminal neuralgia. Clinical Neurophysiology, 2025, 171, pp. 61–66
12. Falco P, Litewczuk D, Di Stefano G, Galosi E, Leone C, De Stefano G, Di Pietro G, Tramontana L, Ciardi MR, Pasculli P, Zingaropoli MA, Arendt-Nielsen L, Truini A. Small fibre neuropathy frequently underlies the painful long-COVID syndrome. Pain. 2024 May 7. doi: 10.1097/j.pain.0000000000003259.
13. Galosi E, Pirone C, Ceccarelli F, Esposito N, Falco P, Leopizzi M, Di Maio V, Tramontana L, De Stefano G, Di Pietro G, Di Stefano G, Garufi C, Leone C, Natalucci F, Orefice V, Alessandri C, Spinelli FR, Truini A, Conti F. Clinical, histologic, and immunologic signatures of Small Fiber Neuropathy in Systemic Lupus Erythematosus. J Peripher Nerv Syst. 2024 Jul 9. doi: 10.1111/jns.12644.
14. Maestrini I, Viganò A, Di Stefano G, Toscano A, Di Piero V. Neurophysiological investigations in a case of primary Paroxysmal Hemicrania-Tic Syndrome. Neurological Sciences 2024. https://doi.org/10.1007/s10072-024-07470-3
15. G. Di Pietro, P. Falco, C. D'Elia, L. Cavalcanti, G. De Stefano, G. Di Stefano, E. Fabiano, E. Galosi, C. Leone, E. Vicenzini, A. Truini, P. Mancini. Predicting value for incomplete recovery in Bell's palsy of facial nerve ultrasound versus nerve conduction study. Clinical Neurophysiology Volume 158, February 2024, Pages 35-42
16. Di Pietro G, Cioffi E, Falco P, Galosi E, De Stefano G, Di Stefano G, Leone C, Martines V, Perotti S, Casali C, Truini A. Nerve ultrasound in Friedreich's Ataxia: enlarged nerves as a biomarker of disease severity. Clin Neurophysiol. 2024 Feb 2;159:75-80. doi: 10.1016/j.clinph.2024.01.004.
17. Leone C, Di Pietro G, Salman Y, Galosi E, Di Stefano G, Caspani O, Garcia-Larrea L, Mouraux A, Treede RD, Truini A. Modulation of the spinal N13 SEP component by high- and low-frequency electrical stimulation. Experimental pain models matter Clinical NeurophysiologyThis link is disabled., 2023, 156, pp. 28–37
18. De Stefano G, Di Pietro G, Truini A, Cruccu G, Di Stefano G. Considerations When Using Gabapentinoids to Treat Trigeminal Neuralgia: A Review. Neuropsychiatric Disease and Treatment.
In Press 2023
19. Asci F, Di Stefano G, Di Santo A, Bianchini E, Leone C, La Cesa S, Zampogna A, Cruccu G, Suppa A. Pain-motor integration in chronic pain: A neurophysiological study. Clin Neurophysiol. 2023 Aug 7;154:107-115.
20. Di Stefano, Giulia; Falco, Pietro; Galosi, Eleonora; De Stefano, Gianfranco; Di Pietro, Giuseppe; Leone, Caterina; Litewczuk, Daniel; Tramontana, Lorenzo; Strano, Stefano; Truini, Andrea. Pain associated with COVID-19 vaccination is unrelated to skin biopsy abnormalities. PAIN Reports 8(5):p e1089, September 2023.
21. Falco P, Galosi E, Di Stefano G, Leone C, Di Pietro G, Tramontana L, De Stefano G, Litewczuk D, Esposito N, Truini A. Autonomic small-fiber pathology in patients with fibromyalgia.
J Pain. 2023 Jul 29:S1526-5900(23)00486-8.
22. De Stefano G, Litewczuk D, Mollica C, Di Pietro G, Galosi E, Leone C, Falco P, Tullo MG, Caramia F, Truini A, Di Stefano G. Sex differences in trigeminal neuralgia: a focus on radiological and clinical characteristics. Neurol Sci. 2023
23. Truini A, Aleksovska K, Anderson CC, Attal N, Baron R, Bennett DL, Bouhassira D, Cruccu G, Eisenberg E, Enax-Krumova E, Davis KD, Di Stefano G, Finnerup NB, Garcia-Larrea L, Hanafi I, Haroutounian S, Karlsson P, Rakusa M, Rice ASC, Sachau J, Smith BH, Sommer C, Tölle T, Valls-Solé J, Veluchamy A.
Joint European Academy of Neurology-European Pain Federation-Neuropathic Pain Special Interest Group of the International Association for the Study of Pain guidelines on neuropathic pain assessment. Eur J Neurol. 2023 May 30.
24. Di Stefano G, Falco P, Galosi E, Di Pietro G, Leone C, Truini A. A systematic review and metanalysis of neuropathic pain associated with coronavirus disease 2019. Eur J Pain. 2022 Nov 11.
25. Devigili G, Di Stefano G, Donadio V, Frattale I, Mantovani E, Nolano M, Occhipinti G, Provitera V, Quitadamo S, Tamburin S, Toscano A, Tozza S, Truini A, Valeriani M, de Tommaso M. Clinical criteria and diagnostic assessment of fibromyalgia: position statement of the Italian Society of Neurology-Neuropathic Pain Study Group. Neurol Sci. 2023 May 24. doi: 10.1007/s10072-023-06836-3.
26. Leone C, Galosi E, Esposito N, Falco P, Fasolino A, Di Pietro G, Di Stefano G, Camerota F, Vollert J, Truini A. Small-fibre damage is associated with distinct sensory phenotypes in patients with fibromyalgia and small-fibre neuropathy. Eur J Pain. 2022 Oct 31. doi: 10.1002/ejp.2049
27. De Stefano, G., Leone, C., Di Pietro, G., Truini, A., Di Stefano, G. Unravelling the role of unmyelinated nerve fibres in trigeminal neuralgia with concomitant continuous pain Clinical Neurophysiology, 2022, 142, pp. 52–58.
28. Galosi E, Leonardi L, Falco P, Di Pietro G, Fasolino A, Esposito N, Leone C, Di Stefano G, Inghilleri M, Luigetti M, Giovanni A, Truini A. Functional and morphometric assessment of small-fibre damage in late-onset hereditary transthyretin amyloidosis with polyneuropathy: the controversial relation between small-fibre-related symptoms and diagnostic test findings. Amyloid. 2022 Sep 12:1-8.
29. Gualdani R, Gailly P, Yuan JH, Yerna X, Di Stefano G, Truini A, Cruccu G, Dib-Hajj SD, Waxman SG. A TRPM7 mutation linked to familial trigeminal neuralgia: Omega current and hyperexcitability of trigeminal ganglion neurons. Proc Natl Acad Sci U S A 2022 Sep 20;119(38):e2119630119. DOI: 10.1073/pnas.2119630119.
30. Galosi E, Falco P, Di Pietro G, Leone C, Esposito N, De Stefano G, Di Stefano G, Truini A. The diagnostic accuracy of the Small Fiber Neuropathy Symptoms Inventory Questionnaire (SFN-SIQ) for identifying pure small fiber neuropathy. J Peripher Nerv Syst. 2022 Sep 29. doi: 10.1111/jns.12513
31. Galosi E, Truini A, Di Stefano G. A Systematic Review and Meta-Analysis of the Prevalence of Small Fibre Impairment in Patients with Fibromyalgia. Diagnostics 2022, 12(5), 1135; https://doi.org/10.3390/diagnostics12051135.
32. Dominguez M, Di Stefano G. Novel ways of approaching the pharmacologic treatment of trigeminal neuralgia. Headache. Headache. 2022 May;62(5):540-542.
doi: 10.1111/head.14316
33. Mouraux A, Bloms-Funke P, Boesl I, Caspani O, Chapman SC, Di Stefano G, Finnerup NB, Garcia-Larrea L, Goetz M, Kostenko A, Pelz B, Pogatzki-Zahn E, Schubart K, Stouffs A, Truini A, Tracey I, Troconiz IF, Van Niel J, Vela JM, Vincent K, Vollert J, Wanigasekera V, Wittayer M, Phillips KG, Treede RD. IMI2-PainCare-BioPain-RCT3: a randomized, double-blind, placebo-controlled, crossover, multi-center trial in healthy subjects to investigate the effects of lacosamide, pregabalin, and tapentadol on biomarkers of pain processing observed by electroencephalography (EEG). Trials. 2021 Jun 17;22(1):404.
34. Caterina Leone, Giulia Di Stefano, Giuseppe Di Pietro, Petra Bloms-Funke, Irmgard Boesl, Ombretta Caspani, Sonya C Chapman, Nanna Brix Finnerup, Luis Garcia-Larrea, Tom Li, Marcus Goetz, André Mouraux, Bernhard Pelz, Esther Pogatzki-Zahn, Andreas Schilder, Erik Schnetter, Karin Schubart, Irene Tracey, Inaki F Troconiz, Hans Van Niel, Jose Miguel Vela Hernandez, Katy Vincent, Jan Vollert, Vishvarani Wanigasekera, Matthias Wittayer, Keith G Phillips, Andrea Truini, Rolf-Detlef Treede. IMI2-PainCare-BioPain-RCT2 protocol: a randomized, double-blind, placebo-controlled, crossover, multicenter trial in healthy subjects to investigate the effects of lacosamide, pregabalin, and tapentadol on biomarkers of pain processing observed by non-invasive neurophysiological measurements of human spinal cord and brainstem activity. Trials, 2022, 23(1), 739
35. Leone C, Di Lionardo A, Di Pietro G, Di Stefano G, Falco P, Blockeel AJ, Caspani O, Garcia-Larrea L, Mouraux A, Phillips KG, Treede RD, Truini A, “How different experimental models of secondary hyperalgesia change the nociceptive flexion reflex”. CLINPH 2021 Dec;132(12):2989-2995;
36. Di Pietro G, Di Stefano G, Leone C, Di Lionardo A, Sgrò E, Blockeel AJ, Caspani O, Garcia-Larrea L, Mouraux A, Geoffrey Phillips K, Treede RD, Valeriani M, Truini A, “The N13 spinal component of somatosensory evoked potentials is modulated by heterotopic noxious conditioning stimulation: evidence for involvement of spinal wide-dynamic range neurons”. Neurophysiol Clin. 2021 Dec;51(6):517-523.
37. Di Lionardo et al. Modulation of the N13 component of the somatosensory evoked potentials in an experimental model of central sensitization in humans. Sci Rep. 2021 Oct 21;11(1):20838.
38. Leandri M, Di Stefano G, Truini A, Marinelli L. Early nociceptive evoked potentials recorded from the scalp. Clin Neurophysiol. 2021 Jun 28:S1388-2457(21)00620-9.
39. Di Stefano G, Di Lionardo A, Di Pietro G, Cruccu G, Truini A. Pharmacotherapeutic Options for Managing Neuropathic Pain: A Systematic Review and Meta-Analysis. Pain Res Manag. 2021 Apr 26;2021:6656863.
40. Guerra A, Vicenzini E, Cioffi E, Colella D, Cannavacciuolo A, Pozzi S, Caccia B, Paparella G, Di Stefano G, Berardelli A, Bologna M. Effects of Transcranial Ultrasound Stimulation on Trigeminal Blink Reflex Excitability. 2021 Brain Sciences May 15;11(5):645.
41. G Di Stefano, G De Stefano, C Leone, A Di Lionardo, G Di Pietro, E Sgro, C Mollica, G Cruccu, A Truini. Real-world effectiveness and tolerability of carbamazepine and oxcarbazepine in 354 patients with trigeminal neuralgia. Eur J Pain. 2021 May;25(5):1064-1071.
42. Gualdani R, Yuan JH, Effraim P, Di Stefano G, Truini A, Cruccu G, Dib-hajj SD, Gailly P, and Waxman SG. Trigeminal neuralgia TRPM8 mutation: enhanced activation, basal [Ca2+]i and menthol response. Neurol Genet. 2021 Jan 11;7(1):e550.
43. Cruccu G, Di Stefano G, Truini A. Trigeminal Neuralgia. N Engl J Med. 2020 Aug 20;383(8):754-762.
44. Di Stefano G, Di Lionardo A, Di Pietro G, Truini A. Neuropathic Pain Related to Peripheral Neuropathies According to the IASP Grading System Criteria. Brain Sci. 2020 Dec 22;11(1):1.
45. Paparella G, Di Stefano G, Fasolino A, Di Pietro G, Colella D, Truini A, Cruccu G, Berardelli A, Bologna M. Painful stimulation increases spontaneous blink rate in healthy subjects. Sci Rep. 2020 Nov 17;10(1):20014.
46. Galosi E, Di Pietro G, La Cesa S, Di Stefano G, Leone C, Fasolino A; Di Lionardo A, Leonetti F, Buzzetti R, Mollica C, Cruccu G, Truini A. Differential involvement of myelinated and unmyelinated nerve fibers in painful diabetic polyneuropathy. Muscle Nerve. 2021 Jan;63(1):68-74.
47. Di Stefano G, De Stefano G, Leone C, Cruccu G, Fiorelli M, Truini A, Caramia F. Concomitant continuous pain in patients with trigeminal neuralgia is associated with trigeminal nerve root atrophy. Cephalalgia 2020 Nov;40(13):1502-1510.
48. Fasolino A, Di Stefano G, Leone C, Galosi E, Gioia C, Lucchino B, Terracciano A, Di Franco M, Cruccu G, Truini A. Small-fibre pathology has no impact on somatosensory system function in patients with fibromyalgia. Pain. 2020 Oct;161(10):2385-2393.
49. Leone C, Di Lionardo A, Diotallevi G, Mollica C, Di Pietro G, Di Stefano G, La Cesa S, Cruccu G, Truini A. Conduction velocity of the cold spinal pathway in healthy humans. Eur J Pain. 2020 Nov;24(10):1923-1931.
50. G Di Stefano, G De Stefano, A Di Lionardo, G Cruccu, A Truini. Pharmacotherapeutic Options for Managing Pain in Multiple Sclerosis. CNS Drugs. 2020 Jul;34(7):749-761.
51. Di Stefano G, Yuan JH, Cruccu G, Waxman SG, Dib-Hajj SD, Truini A. Familial trigeminal neuralgia - a systematic clinical study with a genomic screen of the neuronal electrogenisome. Cephalalgia. 2020 Jul;40(8):767-777.
52. Di Stefano G, Di Lionardo A, La Cesa S, Di Pietro G, Fasolino A, Galosi E, Leone C, Cruccu G, Marinelli L, Leandri M, Truini A. The new micropatterned interdigitated electrode for selective assessment of the nociceptive system. European Journal of Pain. 2020 May;24(5):956-966.
53. Bendtsen L, Zakrzewska JM, Abbott J, Braschinsky M, Di Stefano G, Donnet A, Eide PK, Leal PRL, Maarbjerg S, May A, Nurmikko T, Obermann M, Jensen TS, Cruccu G. European Academy of Neurology guideline on trigeminal neuralgia. Eur J Neurol. 2019 Jun;26(6):831-849.19.
54. Di Stefano G, Galosi E, Di Lionardo A, Truini A, Cruccu G. Acetyl-L-carnitine in painful peripheral neuropathy: a systematic review. J Pain Res. 2019 Apr 26;12:1341-1351
55. Di Stefano G, Maarbjerg S, Truini A. Trigeminal neuralgia secondary to multiple sclerosis: from the clinical picture to the treatment options. J Headache Pain. 2019 Feb 19;20(1):20.
56. Leone C, Dufour A, Di Stefano G, Fasolino A, Di Lionardo A, La Cesa S, Galosi E, Valeriani M, Nolano M, Cruccu G, Truini A. Cooling the skin for assessing small-fibre function. Pain. 2019 Sep;160(9):1967-1975.
57. Cruccu G, Di Stefano G, Marchettini P, Truini A. Micronized Palmitoylethanolamide: a Post-Hoc Analysis of a Controlled Study in Patients with Low Back Pain – Sciatica. CNS Neurol Disord Drug Targets. 2019;18(6):491-495 23.
58. Di Stefano G, Maarbjerg S, Nurmikko T, Truini A, Cruccu G. Triggering trigeminal neuralgia. Cephalalgia. 2018 May;38(6):1049-1056.
59. Galosi E, La Cesa S, Di Stefano G, Karlsson P, Fasolino A, Leone C, Biasiotta A, Cruccu G, Truini A. A pain in the skin. Regenerating nerve sprouts are distinctly associated with ongoing burning pain in patients with diabetes. Eur J Pain. 2018 Nov;22(10):1727-1734.
60. Mancini F, Pepe A, Bernacchia a, Di Stefano G, Mouraux A, Iannetti GD. Characterising the short-term habituation of event-related evoked potentials. eNeuro. 2018 Sep 28;5(5):ENEURO.0014-18.2018.
61. Di Stefano G, Truini A, Cruccu G. Current and Innovative Pharmacological Options to Treat Typical and Atypical Trigeminal Neuralgia. Drugs. 2018 Sep;78(14):1433-1442.
62. Zakrzewska J, Palmer J, Bendtsen L, Di Stefano G, Ettlin D, Maarbjerg S, Obermann M, Morisset V, Steiner D, Tate S and Cruccu G. Challenges recruiting to a proof-of-concept pharmaceutical trial for a rare disease: the trigeminal neuralgia experience. Trials. 2018 Dec 27;19(1):704.
63. Maarbjerg S, Di Stefano G, Bendtsen L, Cruccu G. Trigeminal neuralgia - diagnosis and treatment. Cephalalgia. 2017 Jun;37(7):648-657.
64. Di Stefano G, La Cesa S, Leone C, Pepe A, Galosi E, Fiorelli M, Valeriani M, Lacerenza M, Pergolini M, Biasiotta A, Cruccu G, Truini A. Diagnostic accuracy of laser evoked potentials in diabetic neuropathy. Pain. 2017 Jun;158(6):1100-1107.
65. Di Stefano G, Limbucci N, Cruccu G, Truini A, Mangiafico S. Trigeminal neuralgia completely relieved after stent assisted coiling of a superior cerebellar artery aneurysm. World Neurosurg. 2017 May;101:812.e5-812.e9.
66. Di Stefano G, Tinelli E, Truini A. An unusual case of simultaneous bilateral trigeminal neuralgia due to multiple sclerosis. J Oral Facial Pain Headache. 2017 Fall;31(4):e4-e6.
67. Di Stefano G, Truini A. Pharmacological treatment of trigeminal neuralgia. Expert Rev Neurother. 2017 Oct;17(10):1003-1011.
68. La Cesa S, Di Stefano G, Leone C, Pepe A, Galosi E, Alu F, Fasolino A, Cruccu G, Valeriani M, Truini A.
Skin denervation does not alter cortical potentials to surface concentric electrode stimulation: a comparison with laser evoked potentials and contact heat evoked potentials. Eur J Pain. 2018 Jan;22(1):161-169.
69. Bufacchi, R.J., Sambo, C.F., Di Stefano, G., Cruccu, G., Iannetti, G.D. Pain outside the body: Defensive peripersonal space deformation in trigeminal neuralgia. Sci Rep. 2017 Oct 2;7(1):12487.
70. Cruccu G, Di Stefano G, Fattaposta F, Jann S, Padua L, Schenone A, Truini A. L-Acetyl-carnitine in Patients with Carpal Tunnel Syndrome: Effects on Nerve Protection, Hand Function and Pain. CNS Drugs. 2017 Dec;31(12):1103-1111.
71. Di Stefano G, Celletti C, Baron R, Castori M, Di Franco M, La Cesa S, Leone C, Pepe A, Cruccu G, Truini A, Camerota F. Central sensitization as the mechanism underlying pain in joint hypermobility syndrome/Ehlers–Danlos syndrome, hypermobility type. Eur J Pain. 2016 Sep;20(8):1319-25.
72. Leone C, Federico V, La Cesa S, Russo E, Di Stefano G, Finsinger P, Labriola R, Cruccu G, Petrucci MT, Truini A. An observational study assessing peripheral neuropathy related to multiple myeloma. Neurol Sci. 2016 Jul;37(7):1141-3.
73. Moayedi M, Di Stefano G, Stubbs MT, Djeugam B, Liang M, Iannetti GD. Nociceptive-Evoked Potentials Are Sensitive to Behaviorally Relevant Stimulus Displacements in Egocentric Coordinates. eNeuro. 2016 Jul 11;3(3).
74. Minichino A, Delle Chiaie R, Cruccu G, Piroso S, Di Stefano G, Francesconi M, Bersani FS, Biondi M, Truini A. Pain-processing abnormalities in bipolar I disorder, bipolar II disorder, and schizophrenia: A novel trait marker for psychosis proneness and functional outcome. Bipolar Disord. 2016 Nov;18(7):591-601.
75. Truini A, Biasiotta A, Onesti E, Di Stefano G, Ceccanti M, La Cesa S, Pepe A, Giordano C, Cruccu G, Inghilleri M. Small-fibre neuropathy related to bulbar and spinal-onset in patients with ALS. J Neurol. 2015;262(4):1014-8.
76. Truini A, Gerardi MC, Di Stefano G, La Cesa S, Iannuccelli C, Pepe A, Sarzi-Puttini P, Cruccu G, Di Franco M. Hyperexcitability in pain matrices in patients with fibromyalgia. Clin Exp Rheumatol. 2015 Jan-Feb;33(1 Suppl 88):S68-72.
77. Truini A, Piroso S, Pasquale E, Notartomaso S, Di Stefano G, Lattanzi R, Battaglia G, Nicoletti F, Cruccu G. N-acetyl-cysteine, a drug that enhances the endogenous activation of group-II metabotropic glutamate receptors, inhibits nociceptive transmission in humans. Mol Pain. 2015 Mar 20;11:14.
78. Lopergolo D, Isak B, Gabriele M, Onesti E, Ceccanti M, Capua G, Fionda L, Biasiotta A, Di Stefano G, La Cesa S, Frasca V, Inghilleri M. Cutaneous silent period recordings in demyelinating and axonal polyneuropathies. Clin Neurophysiol. 2015 Sep;126(9):1780-9.
79. Truini A, Biasiotta A, Di Stefano G, Leone C, La Cesa S, Galosi E, Piroso S, Pepe A, Giordano C, Cruccu G. Does the epidermal nerve fibre density measured by skin biopsy in patients with peripheral neuropathies correlate with neuropathic pain? Pain. 2014 Apr;155(4):828-32.
80. La Cesa S, Tinelli E, Toschi N, Di Stefano G, Collorone S, Aceti A, Francia A, Cruccu G, Truini A, Caramia F. fMRI pain activation in the periaqueductal gray in healthy volunteers during the cold pressor test. Magn Reson Imaging. 2014 Apr;32(3):236-40.
81. Biasiotta A, Casato M, La Cesa S, Colantuono S, Di Stefano G, Leone C, Carlesimo M, Piroso S, Cruccu G, Truini A. Clinical, neurophysiological, and skin biopsy findings in peripheral neuropathy associated with hepatitis C virus-related cryoglobulinemia. J Neurol. 2014 Apr;261(4):725-31.
82. Di Stefano G, La Cesa S, Truini A, Cruccu G. Natural history and outcome of 200 outpatients with classical trigeminal neuralgia treated with carbamazepine or oxcarbazepine in a tertiary centre for neuropathic pain. J Headache Pain. 2014 Jun 9;15(1):34.
83. Cruccu G, Pennisi EM, Antonini G, Biasiotta A, di Stefano G, La Cesa S, Leone C, Raffa S, Sommer C, Truini A. Trigeminal isolated sensory neuropathy (TISN) and FOSMN syndrome. Despite a dissimilar disease course do they share common pathophysiological mechanisms? BMC Neurol. 2014 Dec 19;14(1):248.
84. Truini A, Biasiotta A, Di Stefano G, La Cesa S, Leone C, Cartoni C, Leonetti F, Casato M, Pergolini M, Petrucci MT, Cruccu G. Peripheral nociceptor sensitization mediates allodynia in patients with distal symmetric polyneuropathy. J Neurol. 2013 Mar;260(3):761-6.
85. Onesti E, Gabriele M, Cambieri C, Ceccanti M, Raccah R, Di Stefano G, Biasiotta A, Truini A, Zangen A, Inghilleri M. H-coil repetitive transcranial magnetic stimulation for pain relief in patients with diabetic neuropathy. Eur J Pain. 2013 Oct;17(9):1347-56.7
86. Di Stefano G, La Cesa S, Biasiotta A, Leone C, Pepe A, Cruccu G, Truini A. Laboratory tools for assessing neuropathic pain. Neurol Sci. 2012 May; 33 Suppl 1:S5-7.
87. Truini A, Galeotti F, La Cesa S, Di Rezze S, Biasiotta A, Di Stefano G, Tinelli E, Millefiorini E, Gatti A, Cruccu G. Mechanisms of pain in multiple sclerosis: A combined clinical and neurophysiological study. Pain 2012 Oct;153(10):2048-54.
88. Truini A, Leone C, Di Stefano G, Biasiotta A, La Cesa S, Teofoli P, Padua L, Cruccu G. Topographical distribution of warmth, burning and itch sensations in healthy humans. Neurosci Lett. 2011 Apr 25;494(2):165-8.
89. Leone C, Biasiotta A, La Cesa S, Di Stefano G, Cruccu G, Truini A. Pathophysiological mechanisms of neuropathic pain. Future Neurology 2011, 6(4), pp. 497–509.
90. Truini A, Vergari M, Biasiotta A, La Cesa S, Gabriele M, Di Stefano G, Cambieri C, Cruccu G, Inghilleri M, Priori A. Transcutaneous spinal direct current stimulation inhibits nociceptive spinal pathway conduction and increases pain tolerance in humans. Eur J Pain. 2011 Nov;15(10):1023-7.
91. Truini A, Biasiotta A, Di Stefano G, La Cesa S, Leone C, Cartoni C, Federico V, Petrucci MT, Cruccu G. Palmitoylethanolamide restores myelinated-fibre function in patients with chemotherapy-induced painful neuropathy. CNS Neurol Disord Drug Targets. 2011 Dec;10(8):916-20.
92. Truini A, Biasiotta A, La Cesa S, Di Stefano G, Galeotti F, Petrucci MT, Inghilleri M, Cartoni C, Pergolini M, Cruccu G. Mechanism of pain in distal symmetric polyneuropathy: a combined clinical and neurophisiological study. Pain 2010 Sep; 150(3):516-21.

Textbook

1. “Sistema Somatosensoriale”. Di Stefano G, Truini A, Cruccu G. Capitolo II in “La neurologia della Sapienza”, Casa Editrice Esculapio, Ottobre 2012;

2. “Malattie del Sistema Nervoso Periferico”. Truini A, Di Stefano G, Cruccu G. Capitolo IXX in “La neurologia della Sapienza”, Casa Editrice Esculapio, Ottobre 2012.

3. “Chapter 9 TREATMENT OF TRIGEMINAL NEURALGIA- pharmacological” in “Trigeminal Neuralgia and other Cranial Neuralgias: A Practical Personalised Holistic Approach (Oxford Pain Management Library Series) Edited by JOANNA ZAKRZEWSKA and TURO NURMIKKO.