Single channel

Chair (Coordinator) and Rapporteur: MARIALUISA PERROTTA

Module 1:

Activity type
Scienze propedeutiche
SSD
FIS/07
Year
1st year
Semester
1st semester
CFU
1
Hours distribution
12 classroom hours
Lecturers
DANIELA CARNEVALE

Module 2:

Activity type
Scienze biomediche
SSD
BIO/10
Year
1st year
Semester
1st semester
CFU
2
Hours distribution
24 classroom hours
Lecturers
MARIALUISA PERROTTA

Module 3:

Activity type
Scienze biomediche
SSD
BIO/13
Year
1st year
Semester
1st semester
CFU
2
Hours distribution
24 classroom hours
Lecturers
MARIALUISA PERROTTA

Module 4:

Activity type
Scienze biomediche
SSD
MED/03
Year
1st year
Semester
1st semester
CFU
1
Hours distribution
12 classroom hours
Lecturers
DANIELA CARNEVALE

Learning outcomes

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Prerequisites

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Programme

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Introduction
 Units of measurement, fundamental quantities, vectors and vector calculus
 Mechanics
 Force and motion
 Kinetic energy, work and power
 Fluids Density and pressure
 Pascal's Principle and Archimedes
 Fuidodynamics
 Bernoulli's Theorem
 Cardiovascular system
 Stenosis, aneurysm
 Thermodynamics
 Temperature and heat
 Principles of thermodynamics


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 Lipids and fat-soluble vitamins. Phospholipids and biological membranes.
 Simple and complex carbohydrates.
 Overview of cell metabolism.
 ATP as an energy exchanger
 Cellular respiration and carbohydrate metabolism
 Overview of triglyceride metabolism
 Overview of protein metabolism


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Mendel's laws and the discovery of the mechanisms of heredity
 Dominance, incomplete dominance, codominance
 Penetrance and expressiveness
 Concept of gene, allele, genotype, phenotype
 Mitosis and meiosis. Recombination (crossing-over)
 Recombination frequency and genetic maps
 Multiple alleles (ABO groups and MHC)
 Pleiotropy
 Modes of transmission of traits in humans: autosomal traits
dominant and recessive characters
 X-linked characters
 Mitochondrial inheritance
 The genetic code and its properties
 The central dogma of molecular biology: flows of genetic information:
replication, transcription, translation with special reference to eukaryotes
(maturation of the primary transcript, splicing, tRNA, ribosomes and polysomes) -
 The gene: similarities and differences between prokaryotes and eukaryotes
 Gene mutations: main mechanisms and different types (point,
frameshifts, duplication, deletion, unequal crossing-over)
 Evolution and pathology
 Construction of family trees
 Main monogenic diseases (Cystic fibrosis, Neurofibromatosis 1, Haemophilia,
Marfan, etc.)
 Numerical and structural chromosome mutations
 Main chromosome aberration syndromes of the autosomes and the
sex chromosomes
 Recombinant DNA technology: main methods (restriction enzymes,
southern blotting, electrophoresis, RFLPs, sequencing, PCR)

Books

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Fisica applicata alle scienze mediche
Di Gian Marco Contessa


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Appunti di biochimica. Per le lauree triennali (Piccin-Nuova Libraria, 2017)



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Elementi di Biologia e Genetica, David Sadava, David M. Hills, H. Craig Heller,
May R. Berenbaum, ZANICHELLI

Bibliography

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Lessons mode

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Frequency

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Exam mode

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written exam


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written examination


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written exam

Example exam questions

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Arguments

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  • Academic year2024/2025
  • Degree program to which the course belongsNursing
  • Mandatory presenceYes
  • Languageita
  • CFU6 CFU, distributed among 4 integrated didactic modules
  • Total duration72 hours