Nursing

Activity type

Attività formative affini o integrative

SSD

MED/46

Year

1st year

Semester

2nd semester

CFU

1

Hours distribution

12 classroom hours

Lecturers

CLAUDIO TALORA

Activity type

Scienze biomediche

SSD

MED/04

Year

1st year

Semester

2nd semester

CFU

2

Hours distribution

24 classroom hours

Lecturers

CLAUDIO TALORA

Activity type

Scienze biomediche

SSD

MED/07

Year

1st year

Semester

2nd semester

CFU

2

Hours distribution

24 classroom hours

Lecturers

MARCO POMBI

Activity type

Scienze medico - chirurgiche

SSD

MED/08

Year

1st year

Semester

2nd semester

CFU

1

Hours distribution

12 classroom hours

Lecturers

CLAUDIO TALORA

Module: Technical sciences of laboratory medicine
Understanding the role of genomic, protein, and metabolic biomarkers in the diagnosis and monitoring of diseases. Acquiring knowledge of the structure and organization of the clinical pathology laboratory, including workflow, safety, and the management of biological samples. Understanding the types of laboratory tests, the methods of requesting them, and the importance of correct collection, treatment, and storage of biological materials. Knowing the analytical characteristics of a laboratory assay (accuracy, sensitivity, specificity, predictive values, etc.).


Module: Pathology and pathophysiology
N/D
Module: Microbiology
1. Knowledge and Understanding
The student must:
- Understand the classification of microorganisms (bacteria, viruses, fungi, protozoa) and the structural and functional characteristics of prokaryotic and eukaryotic cells.
- Comprehend the general organization, morphology, and physiology of bacteria, including the role and function of bacterial spores.
- Understand the pathogenic action of bacteria, including virulence factors and toxins.
- Know the morphology and reproduction of fungi.
- Comprehend the structure, composition, replication, assembly, and release mechanisms of viral particles.
- Understand the distinction between exogenous and endogenous infections, as well as the sources and transmission routes of infections.
- Recognize the morphological characteristics and biological cycles of medically relevant parasitic protozoa and their infection strategies.
- Understand methods for controlling microorganisms, including disinfection, sterilization, and the role of vaccines in preventing microbial diseases.
- Acquire knowledge about antimicrobial agents, including antibiotics, antibiograms, and antiprotozoal drugs.

2. Application of Knowledge
The student will be able to:
- Identify key microbial characteristics and correlate them with their roles in health and disease.
- Analyze infection sources and transmission pathways to propose appropriate prevention and control measures.
- Apply knowledge of disinfection and sterilization techniques in clinical settings to prevent infection.
- Evaluate the use of vaccines for disease prevention and the effectiveness of antimicrobial therapies based on antibiogram results.

3. Critical Thinking
The student must develop the ability to:
- Critically assess the risk of microbial infections in healthcare settings and identify strategies to mitigate these risks.
- Evaluate the effectiveness of different antimicrobial and disinfection methods in specific clinical contexts.
- Analyze case studies to identify the most effective infection prevention and treatment strategies.

4. Communication Skills
The student will be able to:
- Clearly communicate information about the prevention and management of microbial infections to patients and colleagues.
- Educate patients on the importance of vaccines and adherence to antimicrobial treatments.
- Provide detailed explanations regarding infection control practices to multidisciplinary teams.

5. Learning Skills
The student must:
- Develop the ability to stay updated on advances in microbiology, particularly in antimicrobial resistance and emerging infectious diseases.
- Show autonomy in seeking out and interpreting scientific literature and guidelines on infection prevention and control.
- Continuously evaluate and improve their understanding of microbial behaviors and the clinical implications of microbial infections.


Module: Anatomo pathology bases
N/D

Module: Technical sciences of laboratory medicine
N/D
Module: Pathology and pathophysiology
N/D
Module: Microbiology
Basic knowledge of biology, genetics and physiology of unicellular organisms.


Module: Anatomo pathology bases
N/D

Module: Technical sciences of laboratory medicine
Biomarkers and laboratory medicine. Protein and metabolic genomic markers.
Structure and organisation of the clinical pathology laboratory- Laboratory tests
Laboratory examinations: definition, types and request methods.
Collection, processing and storage of biological materials. Properties and
characteristics of biological samples.
Introduction to the quality system of the clinical pathology laboratory
Laboratory signal interpretation. Biological and analytical variability.
Analytical characteristics of a laboratory assay: accuracy, sensitivity
specificity, predictive values, ROC curve, reference values, causes of error.
Immunochemical diagnostic techniques in immunology: immunodiffusion,
immunoelectrophoresis and immunofixation, nephelometry, method
enzyme immunoassays (direct, indirect and competitive ELISAs, detection strategies
detection, enzymes and substrates), enzyme immunoassays, Western blot.
Spectrophotometric techniques.


Module: Pathology and pathophysiology
Cell and tissue homeostasis, The state of health, Aetiology and pathogenesis. The
Disease-Cell death apotosis, necrosis.
Mechanisms of cell transformation
Introduction to the study of tumours- Aetiology and pathogenesis of tumours-
Classification of tumours- Staging and TNM system. Oncogenes and
oncosuppressors.
Acute Inflammation- Definition and general characteristics
of inflammation. Symptoms of inflammation. Phases of recognition of the
pathogen signalling phase and cytokines
proinflammatory and antiinflammatory
Granulomatous and non-granulomatous chronic inflammation. Leukositis fever proteinase of
acute phase systemic inflammatory response syndrome. Tissue repair
wound healing.
Endocrine system- Synthesis secretion and mechanisms of action of hormones.
Chemical nature of hormones. Hormone receptors. Control of
endocrine function. The arc Hypothalamus-adenohypophysis target glands. Hypo- and hyper
endocrine functions. Primary and secondary hypopfunctions. Primary and
secondary.


Module: Microbiology
- Classification of microorganisms (bacteria, viruses, fungi, protozoa). Structural and functional characteristics of prokaryotic and eukaryotic cells.
- Bacteria: general organisation, morphology and physiology. The bacterial spore. The pathogenic action of bacteria: virulence factors and toxins.
- Mycetes: morphology and reproduction.
- Viruses: structure and composition of the viral particle. Replication, assembly and release.
- Exogenous and endogenous infections, sources and routes of transmission of infections.
- Parasitic protozoa: morphological characteristics of the main groups of medical importance. Biological cycles and infection strategies
- Control of microorganisms: disinfection and sterilisation. Vaccines for the prevention of microbial diseases.
- Antimicrobial agents. Antibiotics and antibiogram. Antiprotozoal drugs


Module: Anatomo pathology bases
N/D

Module: Technical sciences of laboratory medicine
Medicina nel laboratorio. Gli esami: quando, come e perché
Di Mary Louise Turgeon, 2020


Module: Pathology and pathophysiology
Pontieri G.M.: Patologia Generale Ed.Piccin


Module: Microbiology
P. Di Francesco et al. - Microbiologia medica di Patrick R. Murray, Ken S. Rosenthal, Michael A. Pfaller - 2021 - ISBN: 8821453952


Module: Anatomo pathology bases
Patologia generale. Anatomia patologica
Di David S. Strayer, Emanuel Rubin, 2019

Module: Technical sciences of laboratory medicine
N/D
Module: Pathology and pathophysiology
N/D
Module: Microbiology
N/D
Module: Anatomo pathology bases
N/D

Module: Technical sciences of laboratory medicine
N/D
Module: Pathology and pathophysiology
N/D
Module: Microbiology
Lectures that may include on-going learning assessments.


Module: Anatomo pathology bases
N/D

Module: Technical sciences of laboratory medicine
N/D
Module: Pathology and pathophysiology
N/D
Module: Microbiology
mandatory


Module: Anatomo pathology bases
N/D

Module: Technical sciences of laboratory medicine
oral exam


Module: Pathology and pathophysiology
oral and written exam


Module: Microbiology
Ongoing assessment based on in-class questions to evaluate the acquisition of an ability to synthesise the topics explained: 20% of the final mark.
Oral assessment of knowledge of the topics covered during the course, taking into account the ability to link them together in a logical and coherent manner: 80% of the final mark.


Module: Anatomo pathology bases
oral and written exam

Module: Technical sciences of laboratory medicine
What are the main differences between biological and analytical variability in a laboratory test, and how do they influence the interpretation of results?
What are genomic, proteomic, and metabolic markers, and how are they used in laboratory medicine for the diagnosis of diseases?
What are the key analytical characteristics of a laboratory test, and how are they interpreted in terms of accuracy, sensitivity, and specificity? Provide a practical example.
What precautions should be taken in the collection and preservation of biological samples to avoid preanalytical errors?


Module: Pathology and pathophysiology
N/D
Module: Microbiology
The student will be asked to describe the biological cycles of the main microbial agents of clinical interest, mode of transmission and pathogenicity.

Sample questions:
Which pathogens can be transmitted via the faecal-oral route?
What is meant by disinfection?
Describe the phenomenon of antibiotic resistance


Module: Anatomo pathology bases
N/D

Module: Technical sciences of laboratory medicine
N/D
Module: Pathology and pathophysiology
N/D
Module: Microbiology
N/D
Module: Anatomo pathology bases
N/D