Single channel

Chair (Coordinator) and Rapporteur: FERDINANDO NICOLETTI

Module 1:

Activity type
Scienze biomediche
SSD
BIO/10
Year
1st year
Semester
2nd semester
CFU
2
Hours distribution
20 classroom hours
Lecturers
CARLA LETIZIA BUSCETI

Module 2:

Activity type
Scienze biomediche
SSD
BIO/12
Year
1st year
Semester
2nd semester
CFU
2
Hours distribution
20 classroom hours
Lecturers
milena cannella

Module 3:

Activity type
Primo soccorso
SSD
BIO/14
Year
1st year
Semester
2nd semester
CFU
2
Hours distribution
20 classroom hours
Lecturers
FERDINANDO NICOLETTI

Learning outcomes

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Prerequisites

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Programme

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General pharmacology. Characteristics of the main routes of drug administration; definition of bioavailability.
Physiological Pharmacokinetics
Mechanisms of passage of a drug through cell membranes;
Absorption of drugs: physical and chemical properties of molecules.
Distribution and its conditioning factors.
Renal and hepatic excretion of drugs.
Biotransformation: Phase I and Phase II reactions, induction and inhibition phenomena;
Clinical Pharmacokinetics:
First order and zero order kinetics
Definition and determination of half-life, clearance and apparent volume of distribution.
Area under the curve, steady state
Pharmacodynamics
Features Drug-receptor interaction. The relationship between drug concentration and drug-receptor complex.
Definition of ligand agonist, partial agonist, competitive antagonist, reversible and irreversible.
Dose-effect curves, ED50, efficiency and power. the therapeutic index of a drug.
Targets of drugs, types of receptors, effector systems
Principles of general toxicology; Adverse drug reactions
Therapeutic drug monitoring

Books

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Biblioteca Aldo Manuzio
Piazza del Popolo 134 - 04100 - Latina
Farmacologia. Meccanismo d'azione dei farmaci a cura di Pratt WB. & Taylor P., Bologna, Zanichelli, 2002 - Biblioteca Comunale di Latina Aldo Manuzio Inventario LTM 49906 Collocazione LTM 615.1 - Capp. 1-5 - Testo molto approfondito
Farmacologia / Rang & Dale; Milano CEA, 2005 - capp. 2, 3, 7 e 8. - Testo completo per Studenti di Medicina orientato ai meccanismi più che alla clinica.
Farmacologia generale e molecolare: il meccanismo d'azione dei farmaci / [a cura di] Francesco Clementi, Guido Fumagalli, Torino UTET, 2004 Capp. 4, 5, 41-48 - Insieme al successivo sono testi di approfondimento della Farmacologia ma perfettamente utilizzabili da chiunque.
*Farmacologia clinica, a cura di Luciano M. Fuccella, Emilio Perucca, Cesare Sirtori; Torino UTET, 1998 - Capp. 1, 3, 4, 5, 6, 21.

Farmacologia / Mary J. Mycek, Richard A. Harvey, Pamela C. Champe, Bologna Zanichelli, 2000 - Capp. 1 e 2 - Testo di base per le professioni sanitarie

*Questo testo è rintracciabile anche nella biblioteca comunale di Aprilia: Inv. 7781, Coll. S. G. 615 MUC 53/02

Altri testi utilizzabili sono:
Katzung, Piccin Capp. 2,3 e 4
Goodman & Gilman, McGraw-Hill, Capp. 1 e 3
Rossi-Cuomo, Minerva Medica, capp. 1 e 2 (parte)

Bibliography

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Lessons mode

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Frequency

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Exam mode

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Oral examination on topics related to the program

Example exam questions

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Arguments

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  • Academic year2024/2025
  • Degree program to which the course belongsBiomedical Laboratory techniques
  • Mandatory presenceNo
  • Languageita
  • CFU6 CFU, distributed among 3 integrated didactic modules
  • Total duration60 hours