Single channel
Chair (Coordinator) and Rapporteur: DIANA BELLAVIA
Module 1:
- Activity type
- Scienze biomediche
- SSD
- MEDS-02/A
- Year
- 1st year
- Semester
- 2nd semester
- CFU
- 3
- Hours distribution
- 36 classroom hours
- Lecturers
- DIANA BELLAVIA
Module 2:
- Activity type
- Scienze medico - chirurgiche
- SSD
- MEDS-04/A
- Year
- 1st year
- Semester
- 2nd semester
- CFU
- 1
- Hours distribution
- 12 classroom hours
- Lecturers
- BRUNA CERBELLI
Module 3:
- Activity type
- Scienze biomediche
- SSD
- MEDS-03/A
- Year
- 1st year
- Semester
- 2nd semester
- CFU
- 2
- Hours distribution
- 24 classroom hours
- Lecturers
- LUCIA NENCIONI
Objectives
The student must demonstrate an understanding of the etiopathogenetic mechanisms, the development of diseases (etiology) and how they alter normal physiological functions (pathogenesis). This includes learning the cellular, molecular and systemic processes involved.
Learning outcomes
Module:
N/D
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N/D
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N/D
Prerequisites
The student must know structures and functions of the different cell types and kinds of tissues of the human body, and must know the biochemistry of the main biological macromolecules.
Programme
Module:
The student must demonstrate knowledge of the principles of pathology and of the intrinsic link between structural and functional alterations (pathology) and the consequent modifications of normal physiological processes (pathophysiology).
Module:
Role of pathologist; sample management (from processing to staining in cytology and histology)
Diseases of the female genital system: anatomy and histology of the organ; dimension of the problem in each area and histological aspects of the disease processes
Pathology of the uterine cervix (from pap smear to histology; CIN-LSIL-HSIL, carcinoma)
Pathology of the uterine body (endometriosis, adenomyosis, glandular hyperplasia, endometrial carcinoma, leiomyoma, leiomyosarcoma)
Benign ovarian pathology (folliculogenesis, benign cysts, ovarian tumors: of the epithelium, of the sexual cords and stroma, of the germinative epithelium, metastatic neoplasms)
Placental pathology (insertion anomalies, chorioamniositis, placental infarction, cord insertion anomalies, trophoblast diseases: mola, choriocarcinoma)
Benign and malignant breast disease
Pathology of the gastrointestinal tract (esophagus: GERD, esophagitis and neoplasms; stomach: gastritis, carcinomas; colon: polyps and carcinomas)
Cardiovascular pathology(hypertrophy, atherosclerosis, myocardial infarction)
Respiratory diseases (emphysema, acute pulmonary edema, neoplasms)
Module:
General characteristics, structure and virulence of microorganisms (bacteria, viruses, fungi, protozoa).
Overview of the main antimicrobial drugs.
Host-parasite relationships. Definition of infection and infectious disease. Pathogenesis of infections.
Overview of immunology: host defense mechanisms. Immunoprophylaxis.
Nosocomial infections.
Urinary tract infections.
Infections of the genital apparatus and sexually transmitted diseases.
Infection of the fetus and the newborn.
Basic techniques of antisepsis, disinfection and sterilization.
Principles of microbiological diagnostics. Method of collection, transport and storage of microbiological samples.
Books
Module:
General Pathology - Cotran Kumar Collins
Module:
GALLO-d'AMATI
Slides
Module:
Lanciotti Microbiologia clinica. Ambrosiana
Bibliography
Module:
N/D
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N/D
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N/D
Lessons mode
teaching activity will include lectures in classroom when this is possible, based on anti-covid 19 provisions. Alternatively, teaching activity will Frontal lessons with audio-visual and multimedia supports
Frequency
Students must achieve the minimum number of hours provided
Exam mode
The student acquired knowledge will be evaluated through an ongoing exam in Google meet, zoom or in presence, depending on the Covid 19 status
Example exam questions
Module:
N/D
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N/D
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N/D
Arguments
Module:
- Main concepts of health, pathologic process and disease; etiology, pathogenesis, evolution, resolution (exitus). General environmental pathology. Pathology by physical and chemical agents. Biological agents of disease: bacterial exotoxins and endotoxins.Pathology of cell structures: the cell's response to injury: cellular stress, cellular adaptations (hypertrophy, hyperplasia, atrophy, metaplasia), intracellular storage diseases
- Molecular pathology: monogenic diseases (hyperphenylalaninemias, familial hypercholesterolemia, cystic fibrosis).
- Cell/Tissue phenotypic changes: metaplasia, dysplasia, anaplasia and precancerous lesions. Definition of cancer. Morphological and biochemical features of the neoplastic cell. Histogenetic classification of tumors. Clinical criteria for the classification of tumors: grading and staging. Stages of the neoplastic process: initiation, promotion and progression (invasion, metastasis, angiogenesis). Oncogenes and their activation mechanisms. Tumor suppressor genes. Genomic instability. Heredityary tumors.
- Angiophlogosis: stages and progression of the inflammatory process. Participating cells. Exudate. Formation and types of exudate. Cellular mediators of inflammation. Fluid-phase inflammatory mediators. Leukocyte diapedesis. Adhesion molecules. Chemotaxis. Phagocytosis. Chronic inflammation: mediators of inflammation. The granuloma. Conditions associated with granuloma formation.
- The reparative process.
- Mechanisms of thermoregulation.
- Systemic effects of inflammation. Pathogenesis of Fever. Action of Pyrogens. Classification.
- intracellular storage diseases
Module:
Module:
- General characteristics, structure and virulence of microorganisms (bacteria, viruses, fungi, protozoa).Overview of the main antimicrobial drugs.Host-parasite relationships. Definition of infection and infectious disease. Pathogenesis of infections.Overview of immunology: host defense mechanisms. Immunoprophylaxis10 hours
- Nosocomial infections.Urinary tract infections.Infections of the genital apparatus and sexually transmitted diseases.Infection of the fetus and the newborn.10 hours
Sustainability goals
- Academic year2026/2027
- Degree program to which the course belongsMidwifery - Course A - Roma Azienda Policlinico Umberto I
- Mandatory presenceNo
- Languageita
- CFU6 CFU, distributed among 3 integrated didactic modules
- Total duration72 hours