Midwifery

Single channel

Chair (Coordinator) and Rapporteur: ILARIA LAUDADIO

Module 1:

Activity type: Scienze propedeutiche
SSD: FIS/07
Year: 1st year
Semester: 1st semester
CFU: 1
Hours distribution: 12 classroom hours
Lecturers: Selene Onofri

Module 2:

Activity type: Scienze biomediche
SSD: BIO/10
Year: 1st year
Semester: 1st semester
CFU: 2
Hours distribution: 24 classroom hours
Lecturers: giuseppe santini

Module 3:

Activity type: Scienze biomediche
SSD: BIO/13
Year: 1st year
Semester: 1st semester
CFU: 2
Hours distribution: 24 classroom hours
Lecturers: ILARIA LAUDADIO

Module 4:

Activity type: Scienze biomediche
SSD: MED/03
Year: 1st year
Semester: 1st semester
CFU: 1
Hours distribution: 12 classroom hours
Lecturers: Gloria Pessina

Learning outcomes

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Knowledge of the principal biochemical processes and the basic reactions of life.

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Prerequisites

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Knowloedge of the bases of the biology.

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Programme

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The cell and its compartments. Carbohydrates. Lipids. Nucleotides. Amino acids.
Peptide bond and peptides. Proteins: properties and functions. Primary, secondary, tertiary and quaternary structure of proteins. Denaturation and renaturation of proteins. Relationships between three-dimensional structure and biological activity of proteins. Myoglobin and hemoglobin.
Enzymes: structure, function, classification and specificity. Enzyme kinetics.
Enzyme inhibition. Mechanism of action of enzymes. Regulation of enzymatic activity.
Structure and function of biological membranes. Transporters, pumps and ion channels. Hormone receptors and signal transduction mechanisms. Principles of thermodynamics.
Metabolic pathways and their regulation. Glycolysis. Catabolism of hexoses other than glucose. Alcoholic and lactic fermentation. Gluconeogenesis. Glycogen degradation and biosynthesis. Phosphate pentose pathway.
Lipid degradation. -oxidation of fatty acids. Krebs cycle. Electron transport chain and oxidative phosphorylation. Chetonic bodies. Synthesis of fatty acids, triglycerides, phosphoglycerolipids and sphingolipids. Cholesterol biosynthesis.
Metabolism and synthesis of amino acids. Synthesis of urea
Metabolism and synthesis of purine and pyrimidine bases.
Heme metabolism and synthesis.
Bi-test, neonatal screening, principal metabolic pathologies.

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Books

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Lehninger principles of biochimistry.

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Bibliography

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Lessons mode

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100% frontal teaching. In addition to explaining the Professor will try to involve the students.

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Frequency

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More or less one lesson per week of 3 or 4 hours.

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Exam mode

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20 multiple choice questions. Each question will have 5 answers, only one of which is correct. Each question will be worth 1.5 points for a total of 30/30.

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Example exam questions

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What is the β-sheet structure?
What happens to the body in case of prolonged fasting?

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Arguments