CHEMICAL AND PHYSICAL BIOCHEMISTRY Single channel
Chair (Coordinator) and Rapporteur: BRUNO CASCIARO
Module 1: APPLIED PHYSICS
- Activity type
- Scienze propedeutiche
- SSD
- PHYS-06/A
- Year
- N/D
- Semester
- N/D
- CFU
- 2
- Hours distribution
- 20 classroom hours
- Lecturers
Module 2: ELECTRONICAL AND ELECTRICAL MEASURES
- Activity type
- Scienze propedeutiche
- SSD
- IMIS-01/B
- Year
- 1st year
- Semester
- 1st semester
- CFU
- 1
- Hours distribution
- 10 classroom hours
- Lecturers
- MAURIZIO BARBIERI
Module 3: MEDICAL STATISTICAL
- Activity type
- Scienze propedeutiche
- SSD
- MEDS-24/A
- Year
- 1st year
- Semester
- 1st semester
- CFU
- 2
- Hours distribution
- 20 classroom hours
- Lecturers
- LAVINIA GENTILE
Module 4: CHEMISTRY AND PROPEDEUTIC BIOCHEMISTRY
- Activity type
- Scienze biomediche
- SSD
- BIOS-07/A
- Year
- 1st year
- Semester
- 1st semester
- CFU
- 2
- Hours distribution
- 20 classroom hours
- Lecturers
- BRUNO CASCIARO
Learning outcomes
By the end of the course, students will have acquired the fundamentals of inorganic and organic chemistry, physics, medical statistics, and electrical and electronic measurements. Students will understand and learn to apply the methodological tools for understanding and applying the laws governing chemistry, physics, statistics, and electrical and electronic measurements.
Prerequisites
Basic knowledge of high school science subjects (science, mathematics, physics) is essential. A methodological and scientific approach are equally important.
Programme
Module: APPLIED PHYSICS
N/D
Module: ELECTRONICAL AND ELECTRICAL MEASURES
N/D
Module: MEDICAL STATISTICAL
1. Introduction to Medical Statistics
Role and applications of medical statistics in healthcare
Populations and samples
Parameters and statistics
Types of variables
Levels of measurement
2. Descriptive Statistics
Data organization and presentation
Frequency distributions and frequency tables
Graphical presentation of data
Measures of central tendency
Measures of variability and dispersion
The normal distribution
3. Probability and Statistical Inference
Basic concepts of probability
Sampling methods
Sampling distributions
Point estimation and confidence intervals
Hypothesis testing
Statistical significance and significance levels
p-values
4. Introduction to Statistical Tests
Student’s t-test
Introduction to the χ² (chi-square) test
Principles for selecting an appropriate statistical test
Interpretation of statistical results reported in the scientific literature
Module: CHEMISTRY AND PROPEDEUTIC BIOCHEMISTRY
The course program includes the following topics:
GENERAL CHEMISTRY
Structure of the atom. nucleus, electrons, atomic number and mass number. Orbitals and orbitals hybrids. Localization of electrons. The periodic system. Periodic properties and atomic structure of the elements. Octet rule. Ionization potential and affinity for the electron. Anions and cations. The isotopes. The atomic weight. Stable and radioactive isotopes. Chemical bonds. Ionic bond. Covalent bond. Bond energies, lengths and angles. Electronegativity. Coordination bond. Weak intermolecular electrostatic bonds. Nomenclature rules. Oxidation number. Valence. Definition of mole. Avogadro's number. Chemical equations and stoichiometry. The states of matter and the changes of state. The gaseous state. Gas laws. Critical temperature. The liquid state. Properties of liquids. Vapor pressure. Boiling. Specific heat. Heat latent evaporation. The solid state. Properties of solids. Ionic, molecular, covalent solids, metallic. Metallic bond. The solutions. Water as a solvent. Polar and non-polar solvents. Aqueous gas solutions. Effect of temperature and pressure on gas solubility: embolism gaseous. Concentration of a solution and its definition methods. Colligative properties of solutions. Osmotic pressure. Isotonic, hypertonic solutions e hypotonic. Physiological solutions. The chemical equilibrium. Law of action of the masses, equilibrium constant. Principle of equilibrium mobile. Acids and bases. Ionic product of water, pH. Definition of acid and base according to Arrhenius, Bronsted. Acid-base conjugate pairs. Dissociation constant, pka. Strength of acids. Acids proliprotic. Current and total acidity of a solution. Buffer systems. Redox reactions, standard reduction potentials.
ORGANIC CHEMISTRY
Uniqueness of the properties of carbon. Brute, structural, rational, simplified formulas.Hybridization of the carbon atom.Aliphatic hydrocarbons. Alkanes and cycloalkanes, alkenes and alkynes. Physical properties and reactivity.Aromatic hydrocarbons. Delocalization of electrons. Benzene and polycyclic hydrocarbons. Derivatives halogenated hydrocarbons. Functional groups. Alcohols, phenols, thiols and disulfides. Ethers. Thioethers. Aldehydes and Ketones. Properties of the carbonyl group. Carboxylic acids. Acidity of carboxylic acids. Fatty acids. Derivatives of carboxylic acids. Anhydrides. Foreign. Amine. Starches. Amino acids. Isomerism. Conformation, chain, position, geometric, group isomerism functional. Tautomeria. Stereoisomerism.
BIOCHEMICAL PROPEDEUTICS
Carbohydrates. Aldosis and ketosis. Monosis and poliosis. Lipids. Triglycerides. Phospholipids. Biological membranes. Protides. Protein amino acids. Peptide bond. Notes on the structure of proteins. Nucleic acids. Purine and pyrimidine nitrogenous bases. Nucleosides, nucleotides, polynucleotides.
Books
Module: APPLIED PHYSICS
N/D
Module: ELECTRONICAL AND ELECTRICAL MEASURES
N/D
Module: MEDICAL STATISTICAL
Course materials
Recommended textbook: Norman GR, Streiner DL. Biostatistics: The Bare Essentials.
Module: CHEMISTRY AND PROPEDEUTIC BIOCHEMISTRY
"Chimica e Biochimica per le lauree triennali dell'area biomedica" - M. Samaja, R. Paroni – PICCIN
Teaching materials provided by the teacher
Bibliography
Module: APPLIED PHYSICS
N/D
Module: ELECTRONICAL AND ELECTRICAL MEASURES
N/D
Module: MEDICAL STATISTICAL
N/D
Module: CHEMISTRY AND PROPEDEUTIC BIOCHEMISTRY
N/D
Lessons mode
Lessons are held face-to-face, in the classroom with the projection of explanatory slides and explanations by the professors.
Frequency
Mandatory with paper-based attendance recording.
Exam mode
The exam includes written and oral tests, designed to verify the students' knowledge.
Example exam questions
An aqueous solution (1.5 L) of NaCl has a concentration of 3 mM. If 500 mL of water is added, what is the salt concentration?
Arguments
Module: APPLIED PHYSICS
N/D
Module: ELECTRONICAL AND ELECTRICAL MEASURES
N/D
Module: MEDICAL STATISTICAL
- Introduction to medical statistics
- descriptive statistics
- statistical probability
- Statistical Significance and Confidence Intervals
- Main Statistical Tests and Interpretation of Scientific Literature
Module: CHEMISTRY AND PROPEDEUTIC BIOCHEMISTRY
- Introduction to Inorganic Chemistry. Atomic Theories
- Chemical bonds, periodic table, elements and compounds.
- Mole concept, solutions, states of matter and exercises
- Organic Chemistry
- Biochemical propedeutics
Sustainability goals
- Academic year2026/2027
- Degree program to which the course belongsDental Hygiene - Course D - ASL Rieti
- Languageita
- CFU7 CFU, distributed among 4 integrated didactic modules
- Total duration70 hours