CELLULAR AND MOLECULAR BASIS OF LIFE Single channel
Chair (Coordinator) and Rapporteur: MARCO ARTINI
Module 1: APPLIED BIOLOGY
- Activity type
- Scienze biomediche
- SSD
- BIO/13
- Year
- 1st year
- Semester
- 1st semester
- CFU
- 2
- Hours distribution
- 20 classroom hours
- Lecturers
- ROBERTO CARNEVALE
Module 2: GENETICS
- Activity type
- Scienze biomediche
- SSD
- MED/03
- Year
- 1st year
- Semester
- 1st semester
- CFU
- 1
- Hours distribution
- 10 classroom hours
- Lecturers
- ANTONIO PIZZUTI
Module 3: GENERAL PATHOLOGY
- Activity type
- Scienze biomediche
- SSD
- MED/04
- Year
- 1st year
- Semester
- 1st semester
- CFU
- 2
- Hours distribution
- 20 classroom hours
- Lecturers
- PATRIZIA MANCINI
PATRIZIA MANCINI
Module 4: MICROBIOLOGY
- Activity type
- Scienze biomediche, Scienze dell' igiene dentale
- SSD
- MED/07, MED/07
- Year
- 1st year
- Semester
- 1st semester
- CFU
- 2
- Hours distribution
- 20 classroom hours
- Lecturers
- MARCO ARTINI
Objectives
At the end of the course the student must know morpho-functional and metabolic characteristics of the prokaryotic cell
and eukaryotic, the fundamentals of the genetic code and of the regulation of gene expression, of the mechanisms of inheritance e
the nature of gene mutation, aspects of genetic pathology and of development, of molecular and cell pathology and of environmental pathology; acquires knowledge of the fundamentals of neoplastic transformation and inflammation, of pathogenic microorganisms for humans, of relationships between host and pathogenic organisms; the main techniques of classical microbiology and the general principles of immunology.
At the end of the course the student must demonstrate that he has acquired the critical skills and tools necessary to understand the evolutionary approach to biological phenomena; must be able to distinguish the main genetic diseases; be able to distinguish genetic and developmental pathologies, molecular, cellular, environmental, neoplastic and inflammatory pathologies; be able to recognize the morphological, structural and genetic characteristics of microorganisms and their pathogenicity, to understand the mechanisms of action of the main antibacterial and antiviral drugs and be able to distinguish the prevention tools such as vaccines.
Learning outcomes
Module: APPLIED BIOLOGY
N/D
Module: GENETICS
genetic bases of human diseases
Module: GENERAL PATHOLOGY
The General Pathology module aims to provide the basic knowledge to make the student able to understand the molecular and cellular mechanisms that regulate pathological processes in humans. The aim of the knowledge of the etiopathogenetic bases of diseases and pathological processes constitutes the indispensable substrate for the laboratory approach for the prevention, therapy and clinical aspect of human pathologies.
Module: MICROBIOLOGY
General knowledge on microbiology and clinical microbiology
Prerequisites
Module: APPLIED BIOLOGY
N/D
Module: GENETICS
bases of cellular biology
Module: GENERAL PATHOLOGY
In order to understand the teaching contents and achieve the learning objectives, at the beginning of the didactic activities foreseen by the didactic module the student must possess basic school knowledge relating to biology, chemistry and biochemistry.
Module: MICROBIOLOGY
Basic skills in biology and chemistry
Programme
Module: APPLIED BIOLOGY
N/D
Module: GENETICS
Formal characteristics of Mendelian diseases Mitochondrial genetics Cytogenetics principles and methods Multifactorial diseases Epigenetics Genetic testing
Module: GENERAL PATHOLOGY
Etiology and pathogenesis. Concept of health and disease.
Adaptive responses to cell damage: hypertrophy, hyperplasia, atrophy, metaplasia.
Cell death: necrosis, apoptosis.
Physical agents as the cause of disease. Exciting and ionizing radiation. Thermal energy transfer disorders.
Chemical agents as the cause of disease. Environmental pollution.
Body defenses against etiological agents of diseases: innate response, acute and chronic inflammation.
Healing of tissue injuries.
Pathophysiology of fever.
Module: MICROBIOLOGY
History of Microbiology
Hints on bacteriology referred to dentistry
Hints on Virology
Hints on micology
Antibiotics
Vaccines and other forms of immunization
Books
Module: APPLIED BIOLOGY
N/D
Module: GENETICS
Genetica e biologia molecolare
Piccin-Nuova Libraria
Module: GENERAL PATHOLOGY
N/D
Module: MICROBIOLOGY
EUDES LANCIOTTI:
MICROBIOLOGIA CLINICA ultima edizione
Casa Editrice AMBROSIANA
Bibliography
Module: APPLIED BIOLOGY
N/D
Module: GENETICS
N/D
Module: GENERAL PATHOLOGY
N/D
Module: MICROBIOLOGY
N/D
Lessons mode
Module: APPLIED BIOLOGY
N/D
Module: GENETICS
The student will acquire basic knowledge in the field of medical genetics with particular attention to the pathogenetic mechanisms underlying the various genetic diseases (hereditary and acquired) and their transmission according to Mendel's laws
Module: GENERAL PATHOLOGY
The teacher delivers the frontal teaching in the traditional way, with audiovisual aids and with the scheduling of the lessons.
Module: MICROBIOLOGY
Frontal lessons with slides
self evaluation test at the end of each lesson
Frequency
Module: APPLIED BIOLOGY
N/D
Module: GENETICS
in person
Module: GENERAL PATHOLOGY
The attendance is mandatory. The student can take the exam if he reaches 67% of the total number of admissions.
Module: MICROBIOLOGY
At least 66% of lessons
Exam mode
Module: APPLIED BIOLOGY
N/D
Module: GENETICS
Multiple choice
Module: GENERAL PATHOLOGY
The assessment of knowledge will be verified through an oral interview, during which the candidate must demonstrate that he has acquired the knowledge and ability to critically interpret the topics and problems taken into consideration during the course.
To pass the exam it is necessary to achieve a score of no less than 18/30. To achieve a score of 30/30 cum laude, the student must demonstrate that he has acquired excellent knowledge of all the topics covered during the course, being able to connect them in a logical and coherent way, explaining the topics clearly and with appropriate terminology.
Module: MICROBIOLOGY
Quiz with multiple answers
Oral exam in the same day
Example exam questions
Module: APPLIED BIOLOGY
N/D
Module: GENETICS
1. Among the following anomalies, which one cannot be identified by genome sequencing
a) Nonsense variant in the coding sequence of a gene
b) Copy Number Variants (microdeletions and microduplications)
c) Splicing mutation
d) Robertsonian translocation
e) Uniparental disomy of a chromosome (Loss of Heterozygosis)
2. THE risk for multifactorial pathologies is said
a) empirical
b) simple Mendelian
c) compound Mendelian
d multifactorial
e) genomic
Module: GENERAL PATHOLOGY
The questions focus on the topics covered in class and present in the program that is provided to the student at the beginning of the lessons.
Module: MICROBIOLOGY
Bacteria responsible of periodontitis
Herpes viruses
Arguments
Module: APPLIED BIOLOGY
N/D
Module: GENETICS
N/D
Module: GENERAL PATHOLOGY
N/D
Module: MICROBIOLOGY
N/D
- Academic year2024/2025
- Degree program to which the course belongsDental Hygiene
- Mandatory presenceNo
- Languageita
- CFU7 CFU, distributed among 4 integrated didactic modules
- Total duration70 hours