Chemistry

LUISA MARIA MIGNECO
LUISA MARIA MIGNECO
LUIGI FILOCAMO
LUIGI FILOCAMO

As expected results of the learning path, students will be able to describe metabolic pathways leading to bioactive compounds and to relate bioactivities to functional groups and chemical structures; to expand their knowledge in the field of medicinal chemistry and of modern synthetic methodologies applied to the preparation of bioactive molecules; to improve their expertise in correct scientific communication.

A good knowledge of organic chemistry and biochemistry.

Dewick “Chimica, biosintesi e bioattività delle sostanze naturali” PICCIN
Giovanni Greco – Farmacocinetica e Farmacodinamica su Basi Chimico-Fisiche, Edizioni Loghia
Goodman & Gilman’s – The Pharmacological Basis of Therapeutics, McGraw Hill
Lecture notes and handouts available during the course

The course is articulated in 48 h of lectures. Class will be based on slides illustrating the contents of each lesson. A copy of the slides is available at the beginning of the course, together with the detailed programme. Lessons follow a weekly articulation which is approved in advance by the Industrial Chemistry "Consiglio di Area Didattica" (CAD).

optional, recommended

The oral exam will allow to evaluate how knowledge and understanding of the main classes of bioactive natural products and of pharmacologically active compounds have been developed; how the fundamentals of metabolic pathways leading to natural products and of structure activity relationships have been understood. The oral exam will also allow to evaluate if reasoning and critical thinking in the field of modern synthetic methodologies applied to natural products have been developed, and if communication skills fit the educational level of Laurea Magistrale.