MOLECULAR AND CELLULAR BASIS OF LIFE Single channel

Chair (Coordinator) and Rapporteur: ANDREA BELLELLI

Module 1: APPLIED PHYSICS

Activity type
Scienze propedeutiche
SSD
FIS/07
Year
1st year
Semester
1st semester
CFU
1
Hours distribution
12 classroom hours
Lecturers
LUCIANO DE SIO

Module 2: BIOCHEMISTRY

Activity type
Scienze biomediche
SSD
BIO/10
Year
1st year
Semester
1st semester
CFU
2
Hours distribution
24 classroom hours
Lecturers
ANDREA BELLELLI

Module 3: APPLIED BIOLOGY

Activity type
Scienze biomediche
SSD
BIO/13
Year
1st year
Semester
1st semester
CFU
2
Hours distribution
24 classroom hours
Lecturers
ROBERTO CARNEVALE

Module 4: MEDICAL GENETICS

Activity type
Scienze biomediche
SSD
MED/03
Year
1st year
Semester
1st semester
CFU
1
Hours distribution
12 classroom hours
Lecturers
ROBERTO CARNEVALE

Learning outcomes

Module: APPLIED PHYSICS
By the end of the course, the student must:
- Be able to enunciate and explain a fundamental law of physics by using the appropriate notation and the correct symbols for the physics quantities they represent.
- Be able to recognize and apply the fundamental physical laws needed to explain a physics phenomenon in a context that is either generic, applied to medicine, or applied to biology.
- Be able to solve a simple physics problem by calculating the physical quantity and expressing it with the appropriate units of measurement using simple algebraic tools and essential trigonometric functions.


Module: BIOCHEMISTRY
N/D
Module: APPLIED BIOLOGY
N/D
Module: MEDICAL GENETICS
At the end of the course the student must know the main concepts of biology and genetics.

Prerequisites

Module: APPLIED PHYSICS
Conoscenze di base fornite dalla scuola secondaria di secondo grado


Module: BIOCHEMISTRY
None


Module: APPLIED BIOLOGY
N/D
Module: MEDICAL GENETICS
In order to understand the contents of the course and achieve the learning objectives, at the beginning of the teaching activities provided for by the teaching module the student must possess the knowledge of basic biology and genetics.

Programme

Module: APPLIED PHYSICS
Fondamenti di fisica, Cinematica, Statica, Dinamica, Fisica dei liquidi, Onde elettromagnetiche e applicazioni in fisica medica.


Module: BIOCHEMISTRY
0) Safety issues in the classroom and in the laboratory
1) Fundamental physical concepts: mass, force, energy. Mechanics: kinematics, statics, dynamics; its application to the human body.
2) Fluidodynamics with special reference to the circulation of blood.
3) Electromagnetism.
4) The atom: nucleus, electrons, orbitals, hybridization. The chemical bond. The molecules. Energy in chemistry: bond energy, heat, temperature.
5) The physical states of matter: gases, liquids, solids. Weak interactions. The concept of the mole; Avogadro's number. Gaseous mixtures. Solutions; their concentration; osmotic pressure.
6) Chemical reactions: equilibrium and kinetics; catalysis. Redox reactions.
7) Chemical equilibrium in solution: electrolytes; autoprotolysis of water. pH: acids and bases (weak and strong); buffers; hydrolysis; titrations.
8) Organic chemistry: the structure of carbon; hydrocarbons; functional groups; isomerism;
9) Introduction to the Biochemistry: glucides; lipids, aminoacids; proteins, enzymes and biological catalysis; nucleotides and nucleic acids. Blood proteins; coagulation, antibodies.
10) Structure and replication of DNA; protein synthesis.
11) Fundamental concepts on metabolism: la glicolysis; beta oxidation; Krebs cycle; oxidative phosphorilation. Energy in biology.
12) Eukaryotes, prokariotes and viruses; their characteristics. Mechanisms cellular replication in these classes of living organisms. Mitosis and meiosis.
13) The organelles of eukaryotic cells and their functions.
14) Nutrition. Turnover of biological components. Vitamins. Hormones.
15) Heredity and evolution.
16) Medical genetics. Fundamentals and terminology.
17) Classification of genetic diseases (mendelian, chromosomal, multi-determined, mitochondrial)
18) Construction of the genealogical tree
19) Genetic transmission; inheritancy.
20) Consanguineity
21) Genteic counseling
22) Medical genetic tests: diagnostic, preclinical, for genetic carriers, of susceptibility, pharmacogenetic.
23) Non medical genetic tests: forensic
24) Pre-natal diagnosis
25) Defects of the sexual development
26) Genetics in onchology


Module: APPLIED BIOLOGY
N/D
Module: MEDICAL GENETICS
- Mendelism
- The principles behind inheritance
- Extension of Mendelism
- The chromosomal bases of Mendelism
- The chromosomal theory of inheritance
- Monogenic diseases


This program will be carried out during the 1° year 1° semester of the CdS with schedule of the lessons published on the website of the CdS in the section dedicated to the timetable of the lessons.




Books

Module: APPLIED PHYSICS
Materiale didattico fornito dal docente
"Fisica biomedica" Scannicchio Domenico , Ed. Edises
Fisica. Principi ed applicazioni. D.C. Giancoli


Module: BIOCHEMISTRY
It is advisable to use a university level reference text, e.g.:
Stefani, Taddei "Chimica, Biochimica e Biologia per le Professioni Sanitarie", Zanichelli
or: Samaja, Paroni "Chimica e Biochimica per le Lauree Triennali dell'area biomedica", Piccin.


Module: APPLIED BIOLOGY
N/D
Module: MEDICAL GENETICS
For the exam, we suggest a theoretical deepening already from the beginning of the course attendance.
For consultation and in-depth study, the recommended books are:
- Titolo: Elementi di Biologia e genetica
Autori: David Sadava, David M. Hillis, H. Craig Heller, May R. Berenbaum
Casa editrice: Zanichelli

- Titolo: Elementi di Biologia
Autori: Helena Curtis, Sue Barnes, Adriana Schnek, Alicia Massarini
Casa editrice: Zanichelli

- Titolo: Elementi di Biologia
Autori: Solomon, Martin, Martim, Berg
Casa editrice: Edises

- Titolo: Elementi di Biologia e Genetica
Autori: Raven, Johnson, Mason, Losos, Singer
Casa editrice: Piccin


Bibliography

Module: APPLIED PHYSICS
N/D
Module: BIOCHEMISTRY
N/D
Module: APPLIED BIOLOGY
N/D
Module: MEDICAL GENETICS
N/D

Lessons mode

Module: APPLIED PHYSICS
The course takes place with lectures in which students are required a continuous interaction by favoring questions on the topics discussed during the lesson.


Module: BIOCHEMISTRY
The course consists of formal lectures in the classroom. It includes intermediate evaluations.
Attendance is compulsory for at least 75% of the total lectures.


Module: APPLIED BIOLOGY
N/D
Module: MEDICAL GENETICS
The teacher delivers frontal lectures with traditional methods, with audiovisual aids and scheduling of lessons as reported on GOMP Aule/Orari system, published on the website of the CdS.

Frequency

Module: APPLIED PHYSICS
The course takes place with lectures in which students are required a continuous interaction by favoring questions on the topics discussed during the lesson.


Module: BIOCHEMISTRY
N/D
Module: APPLIED BIOLOGY
N/D
Module: MEDICAL GENETICS
Following the Regulations of the CdS, the student is required to attend educational activities, formal, non-formal, vocational. The attendance is checked by the teachers through signature / roll call, based on updated lists provided by the Academic Office, as established by CCL. The certificate of attendance to the course is mandatory and required to the student to be admitted at the final exam.

Exam mode

Module: APPLIED PHYSICS
To Pass the test student must obtain a note of 18/30 for each subject of the integrated teach. Student must possess a sufficient knowledge of the program
To obtain a note of 30/30 with distinction student must possess an excellent knowledge of the whole program using a correct terminology to expose the topics.


Module: BIOCHEMISTRY
The final evaluation is achieved either via a final examination or via the achievement of all the (written) intermediate evaluations.


Module: APPLIED BIOLOGY
N/D
Module: MEDICAL GENETICS
To pass the exam you must obtain a grade of not less than 18/30 in each module. The student must demonstrate that he has acquired sufficient knowledge of the topics covered during the course. To achieve a score of 30/30 cum laude the student must instead demonstrate that he has acquired excellent knowledge of all the topics covered during the course, arguing a linear reasoning with the use of technical terms and using correct linguistic expressions.
The dates of the exams (eight sessions) are published on the CdS website in the relative section.

Example exam questions

Module: APPLIED PHYSICS
A 10 kg box is pulled up a frictionless inclined plane with a slope of 30 ° by a force F. If F is parallel to the inclined plane, what is its modulus expressed in N?


Module: BIOCHEMISTRY
N/D
Module: APPLIED BIOLOGY
N/D
Module: MEDICAL GENETICS
Purification is
A. a translocation mutation
B. a mutation by inversion
C. a mutation by duplication
D. an induced mutation
E. a spontaneous mutation


Arguments

Module: APPLIED PHYSICS



Module: BIOCHEMISTRY



Module: APPLIED BIOLOGY
N/D
Module: MEDICAL GENETICS

  • Introduction of the subjest

  • In-depth analysis of the topics


Sustainability goals

  • Goal3
  • Goal4
  • Goal5
  • Academic year2025/2026
  • Degree program to which the course belongsNursing REPLICA W - ASL LATINA FORMIA - GAETA
  • Mandatory presenceYes
  • Languageita
  • CFU6 CFU, distributed among 4 integrated didactic modules
  • Total duration72 hours