CELLULAR AND MOLECULAR BASIS OF LIFE Single channel
Chair (Coordinator) and Rapporteur: MARA CIRONE
Module 1: APPLIED BIOLOGY
- Activity type
- Scienze biomediche
- SSD
- BIO/13
- Year
- N/D
- Semester
- N/D
- CFU
- 2
- Hours distribution
- 20 classroom hours
- Lecturers
- MARIA SOMMA
Module 2: GENETICS
- Activity type
- Scienze biomediche
- SSD
- MED/03
- Year
- N/D
- Semester
- N/D
- CFU
- 1
- Hours distribution
- 10 classroom hours
- Lecturers
- PAOLA GRAMMATICO
Module 3: GENERAL PATHOLOGY
- Activity type
- Scienze biomediche
- SSD
- MED/04
- Year
- N/D
- Semester
- N/D
- CFU
- 2
- Hours distribution
- 20 classroom hours
- Lecturers
- MARA CIRONE
Module 4: MICROBIOLOGY
- Activity type
- Scienze biomediche
- SSD
- MED/07
- Year
- N/D
- Semester
- N/D
- CFU
- 2
- Hours distribution
- 20 classroom hours
- Lecturers
- OMBRETTA TURRIZIANI
Objectives
The aim of the course is to provide students with the knowledge of the general aspects about biology, genetics, microbiology and general pathology. Thus, the students will be able to explain the general aspects of: -normal cell processes, functions of cell organelles, mechanisms of cell replication; - cell adaptations and pathological cell processes, neoplastic transformation, inflammation and immunity; -the laws of inheritance and transmission of genes, applied to human pathologies; - bacteria and viruses and the main mechanisms involved in their pathogenesis.
Learning outcomes
the student must acquire the basic knowledge of cellular degeneration, oncology and immunology
Prerequisites
the studente must have the bases to learn the lessons
Programme
Module: APPLIED BIOLOGY
- Basic concepts of macromolecules: carbohydrates, lipids, nucleic acids, and proteins.
- Prokaryotic and eukaryotic cells: organelles, characteristics, and functions: nucleus, ribosomes, RER, REL, Golgi apparatus, lysosomes, perixisomes, cytoskeleton; extracellular wall and extracellular matrix, mitochondria, and chloroplasts; cytoskeleton.
- Biological membranes: structure and proposed models; the passage of material across membranes: passive, active, endocytosis, and exocytosis; cell junctions.
- Chromosomes, the cell cycle, and cell division: DNA and proteins, nucleosomes, heterochromatin, eurochromatin, condensed chromosome. Phases of the cell cycle. Mitosis and Meiosis.
- DNA and its role in heredity: characteristics and DNA replication
- Notes on gene expression: transcription, genetic code, and translation
- Effects of rooting on cells
Module: GENETICS
N/D
Module: GENERAL PATHOLOGY
Control and alterations of cell proliferation and differentiation; hyperplasia, hypertrophy, metaplasia, anaplasia. Molecular basis of neoplastic transformation: oncogenes and tumor suppressor genes. Morphology of the neoplastic cell. Invasivity and metastasis. Tumor promotion and progression. Apoptosis and angiogenesis in tumors. Chemical, physical and viral carcinogenesis. Tumor antigens and markers. Tumor classification criteria.
Module: MICROBIOLOGY
Etiological agents of infection in humans with particular reference to bacteria, viruses and fungi: notes on structure and classification, etiopathogenesis, epidemiology and diagnosis.
Etiopathogenesis and diagnosis of infections caused by some exemplary pathogens:
Chronic hepatitis virus
HIV
SARS-CoV-2
Tuberculosis mycobacterium
Aspergillosis
Books
Module: APPLIED BIOLOGY
• Biologia (Edises 2021, di Zelda P. Solomon, Linda R. Diana W. martin
• Fondamentali di Biologia E genetica ( Edises, di Riccardo Pierantoni, Gilda Cobellis, Rosaria Meccariello)
Module: GENETICS
N/D
Module: GENERAL PATHOLOGY
Pontieri
Module: MICROBIOLOGY
PDF lessons and Teaching material provided by the teacher
Bibliography
Module: APPLIED BIOLOGY
N/D
Module: GENETICS
N/D
Module: GENERAL PATHOLOGY
N/D
Module: MICROBIOLOGY
N/D
Lessons mode
classroom lessons
Frequency
obbligatory
Exam mode
oral examination
Example exam questions
B lymphocytes, IgE
Arguments
Module: APPLIED BIOLOGY
- first semester
Module: GENETICS
- The lessons follow the program arguments
Module: GENERAL PATHOLOGY
Module: MICROBIOLOGY
- GENERAL CHARACTERISTICS OF VIRUSES, BACTERIA AND FUNGI
- PATHOGENIC MECHANISMS OF VIRUSES, BACTERIA AND FUNGI
- LUNG INFECTIONS
Sustainability goals
- Academic year2026/2027
- Degree program to which the course belongsImaging and Radiotherapy techniques - Course B - Roma Azienda S. Camillo Forlanini
- Mandatory presenceNo
- Languageita
- CFU7 CFU, distributed among 4 integrated didactic modules
- Total duration70 hours