Imaging and Radiotherapy techniques - Course D - ASL Latina (distretto nord)

Activity type

Scienze biomediche

SSD

BIO/13

Year

N/D

Semester

N/D

CFU

2

Hours distribution

20 classroom hours

Lecturers

DONATELLA PONTI

Activity type

Scienze biomediche

SSD

MED/03

Year

N/D

Semester

N/D

CFU

1

Hours distribution

10 classroom hours

Lecturers

DONATELLA PONTI

Activity type

Scienze biomediche

SSD

MED/04

Year

N/D

Semester

N/D

CFU

2

Hours distribution

20 classroom hours

Lecturers

MARELLA MARODER

Activity type

Scienze biomediche

SSD

MED/07

Year

N/D

Semester

N/D

CFU

2

Hours distribution

20 classroom hours

Lecturers

GIANCARLO PARENTE

At the end of the course, the student will be able to: Understand the structure and function of the cell and of the main biological molecules. Know the basic mechanisms of gene expression and heredity. Recognize cellular and genetic alterations underlying major pathological processes. Describe the essential features of bacteria, viruses, fungi, and parasites of medical relevance. Apply biological and molecular knowledge to the understanding of human physiological and pathological processes.

Module: APPLIED BIOLOGY
N/D
Module: GENETICS
N/D
Module: GENERAL PATHOLOGY
N/D
Module: MICROBIOLOGY
N/D

Module: APPLIED BIOLOGY
BIOLOGY
The atom. The states of matter. H₂O and its properties. Biological molecules: lipids, carbohydrates, proteins, and nucleic acids. Functional groups in organic compounds. Optical isomers. The cell and its organization. Membrane proteins. Transport across membranes: a) passive transport (simple and facilitated diffusion); b) active transport. Cell junctions. Cell communication. Signal sending. Signal reception. Signal transduction. Signal response. Energy and metabolism. Energy, enzymes, ATP synthesis (glycolysis, formation of acetyl-CoA, Krebs cycle, oxidative phosphorylation). The cell cycle. Mitosis. Regulation of the cell cycle. Meiosis. The semiconservative theory of DNA replication: the nitrogen-15 isotope experiment. DNA replication. Mutations. Transcription and post-transcriptional modifications. The genetic code. Translation and post-translational modifications. Control of gene expression (enhancer sequences). Promoter organization. Heterochromatin and euchromatin.



Module: GENETICS
The human genome. Chromosomes. Mutations. Polymorphisms. Genetic diseases. Mendelian inheritance in humans. Family trees. Non-Mendelian inheritance. Molecular-genetic approach to the study of hereditary diseases in humans. Prenatal genetic diagnosis: indications and diagnostic techniques. Gene distribution in populations: basic elements. Multifactorial traits: basic elements. Genetics exercises.


Module: GENERAL PATHOLOGY
General concepts of general pathology: The state of health, disease processes, disease.

Etiology and pathogenesis: Environmental disease, Injury by chemical and physical agents, Nutritional imbalances

Genetic and congenital diseases:
Congenital anomalies: Non-hereditary congenital disease, Errors of morphogenesis,, Teratogenic agents
Genetic disorders: Molecular basis of genetic diseases, Chromosomal abnormalities, Mendelian disorders, Multifactorial disorders, Mitochondrial inheritance

Cellular Pathology:
Cell injury, Cellular response to injury - Stress cellular, Degenerative processes, Adaptive responses (hypertrophy, hyperplasia, atrophy, metaplasia), Cell death - necrosis and apoptosis

Oncology:
Benign and malignant tumors, Definition, nomenclature and classification of cancer, Molecular basis of cancer, Etiology of cancer – carcinogens, Stages of neoplastic process, Invasion and metastasis

Defense mechanisms:
Non-specific defense mechanisms, Inflammation, Causes of inflammation, Acute and chronic inflammation, Cells involved in inflammatory processes, Chemical mediators of inflammation, Phases of the inflammatory process, Granulomas, Reparative phenomena
Specific immunity: Lymphoid organs, Lymphocyte populations, Lymphocyte activation, Specific humoral and cellular immunity



Module: MICROBIOLOGY
MICROBIOLOGY
GENERAL INFORMATION ON MICROORGANISMS;
- STRUCTURE OF THE PROKARYOTIC CELL;
- MORPHOLOGY;
- STRUCTURE OF THE BACTERIAL CELL:
- CELL WALL

- CYTOPLASM
- CYTOPLASMIC MEMBRANE
- CAPSULE
- FLAGELLAE, FIMBRIAE, PILI.
- SPORES;
- DIFFERENCE BETWEEN GRAM+ AND GRAM-
- BACTERIAL METABOLISM
- STRUCTURE OF BACTERIAL DNA
- REPLICATION OF BACTERIAL DNA
- BACTERIAL TAXONOMY
- BACTERIAL CHEMITHERAPITES
- VIRUSES: STRUCTURE, MORPHOLOGY
- FUNGI: STRUCTURE, MORPHOLOGY
- PROTOZOA: STRUCTURE, MORPHOLOGY
- STAPHYLOCOCCI
- STREPTOCOCCI
- NEISSERIA
- PSEUDOMONAS
- SALMONELLA
- CYTOMEGALOVIRUS
- HERPESVIRUS
- MALARIA
- MENINGITIS
- TOXOPLASMOSIS
- CANDIDIASIS.

Module: APPLIED BIOLOGY
FONDAMENTI DI BIOLOGIA E GENETICA EDISES


Module: GENETICS
FONDAMENTI DI BIOLOGIA E GENETICA


Module: GENERAL PATHOLOGY

Pontieri GM Elementi di Patologia Generale. Ed. PICCIN
Teaching/learning material (slides) used for lessons



Module: MICROBIOLOGY
PRINCIPLES OF CLINICAL MICROBIOLOGY FOR NURSING
IGNAZIO CASTIGLIUOLO
PICCIN PUBLISHER

LECTURE SLIDES

Module: APPLIED BIOLOGY
N/D
Module: GENETICS
N/D
Module: GENERAL PATHOLOGY
N/D
Module: MICROBIOLOGY
N/D

Module: APPLIED BIOLOGY
N/D
Module: GENETICS
N/D
Module: GENERAL PATHOLOGY
N/D
Module: MICROBIOLOGY
N/D

mandatory

written test

Red-green color blindness is an X-linked recessive disorder in humans.
A friend of yours has a father who is color-blind. Her mother has normal color vision, but her maternal grandfather was color-blind.
What is the probability that your friend is color-blind?

Which of the following properties characterizes facilitated diffusion?
a. A much higher diffusion rate compared to simple diffusion
b. Specificity of the carrier protein for the solute being transported
c. The number of carrier proteins being a limiting factor for transport efficiency and rate

First-degree burns are characterized by:
A. Presence of blisters
B. Necrosis of the epidermis and dermis
C. Presence of ulcers
D. Redness

Module: APPLIED BIOLOGY



Module: GENETICS



Module: GENERAL PATHOLOGY

• Introduction to General pathology.Environmental disease, Injury by chemical and physical agents, Nutritional imbalances (two lessons)
  • Books: Pontieri GM Elementi di Patologia Generale. Ed. PICCIN.Teaching/learning material (slides) used for lessons


• Developmental pathology. ongenital anomalies and non-hereditary congenital diseases. Morphogenesis errors and teratogenic factors. 
  • Books: Pontieri GM Elementi di Patologia Generale. Ed. PICCIN.Teaching/learning material (slides) used for lessons


• Genetic pathology. Molecular basis of genetic pathology. Chromosomal anomalies. Mendelian disorders . Multifactorial pathologies. Mitochondrial inheritance.
  • Books: Pontieri GM Elementi di Patologia Generale. Ed. PICCIN.Teaching/learning material (slides) used for lessons


• Cellular pathology. Cellular damage. Cellular response to damage: cellular stress and degenerative processes. Adaptive responses.Cell death.
  • Books: Pontieri GM Elementi di Patologia Generale. Ed. PICCIN.Teaching/learning material (slides) used for lessons


• Oncology. Benign and malignant tumors: definition, nomenclature and classification.  Molecular basis of cancer. Tumor etiology. Stages of neoplastic process, Invasion and metastasis.
  • Books: Pontieri GM Elementi di Patologia Generale. Ed. PICCIN.Teaching/learning material (slides) used for lessons


• Defense mechanisms: Nonspecific defense mechanisms: Acute and chronic inflammation. Cells involved in inflammatory processes. Chemical mediators of inflammation. Phases of inflammatory process. Granulomas. Repair. Specific immunity: Lymphoid organs. Lymphocyte populations. Lymphocyte activation. Humoral and cellular specific immunity.
  • Books: Pontieri GM Elementi di Patologia Generale. Ed. PICCIN.Teaching/learning material (slides) used for lessons