Single channel

Chair (Coordinator) and Rapporteur: VALERIA MANGANELLI

Module 1:

Activity type
Scienze biomediche
SSD
BIOS-10/A
Year
1st year
Semester
1st semester
CFU
2
Hours distribution
20 classroom hours
Lecturers
VALERIA MANGANELLI

Module 2:

Activity type
Scienze biomediche
SSD
MEDS-01/A
Year
1st year
Semester
1st semester
CFU
1
Hours distribution
10 classroom hours
Lecturers
TINA GAROFALO

Module 3:

Activity type
Scienze biomediche
SSD
MEDS-02/A
Year
1st year
Semester
1st semester
CFU
2
Hours distribution
20 classroom hours
Lecturers
TINA GAROFALO
VALERIA MANGANELLI

Module 4:

Activity type
Scienze biomediche
SSD
MEDS-03/A
Year
1st year
Semester
1st semester
CFU
2
Hours distribution
20 classroom hours
Lecturers
Bernardetta Palazzotti

Learning outcomes

Understanding the molecular, cellular, and tissue alterations responsible for certain pathologies
Communication skills
Basic knowledge of general biology
Ability to apply knowledge

Prerequisites

To address the course of cellular and molecular bases of life, the student must have a general knowledge of Biology, Genetics and Biochemistry acquired during the high school training course.

Programme

Module:
Structure and function of biological molecules: monosaccharides, amino acids, nucleotides, lipids.
-Evolution Cell: levels of organization and characteristics of living organisms. Prokaryotes and eukaryotes. Characteristics of animal cells, plant. Bacteria and viruses.
-structure And function of eukaryotic cells: the plasma membrane. Spreading: passive and active transport. Membrane potential and electrochemical gradient. Endocytosis and exocytosis. Membranous apparatus. Mitochondria. Nucleus, cytoskeleton, cell cycle: mitosis and meiosis.



Module:
• The human genome: DNA structure and function
• Chromosomes
• Basic genetic terminology: gene loci, genes, alleles, genotype, and phenotype
• Structural genome alterations: molecular basis of mutations and mutagenic agents, DNA repair mechanisms
• Overview of mutation types: gene (point) mutations, chromosomal mutations, and genomic mutations
• Cancer as a genetic disease: definition of oncogenes and tumor suppressor genes.


Module:
N/D
Module:
Bacterial cell structure
Microbial growth
Bacterial replication and sporulation
Bacterial metabolism
Bacterial genetics
Transmission of infection
Bacterial pathogenesis
Antibacterial drugs
Principles of virology: structure, replication, and pathogenesis
Principles of fungi: structure, replication, and pathogenesis
Microbiological diagnosis
Sterilization and disinfection
Vaccines and sera
Medically important microorganisms: Batteri (Stafilococchi, Streptococchi, Clostridi, Enterobatteri, Helicobacter, Haemophilus, Pseudomonas, Micobatteri, Neisserie, Clamidie, Micoplasmi, Corinebatteri); Virus (Herpesvirus, Citomegalovirus, virus influenzale, Virus dell’epatite, Virus HIV, Papilloma virus, Coronavirus); fungi (Candida, Aspergillus, Dermatofiti)


Books

Module:
Elementi di Biologia e genetica; P. Bonaldo e P. Braghetta, ed Piccin


Module:
Elementi di Biologia e genetica; P. Bonaldo e P. Braghetta, ed Piccin


Module:
N/D
Module:
N/D

Bibliography

Module:
N/D
Module:
N/D
Module:
N/D
Module:
N/D

Lessons mode

classroom lessons

Frequency

Mandatory in the classroom

Exam mode

During the academic year, the students have eight dates available to be assessed, distributed so as not to be superimposed on the performance of the lessons

Example exam questions

Main mechanisms of the inflammatory response
Characteristics of eukaryotic cells

Arguments

Module:



Module:

  • The human genome: DNA structure and function

  • chromosomes

  • Basic genetic terminology: gene loci, genes, alleles, genotype, and phenotype

  • Structural genome alterations: molecular basis of mutations and mutagenic agents, DNA repair mechanisms

  • Overview of mutation types: gene (point) mutations, chromosomal mutations, and genomic mutations

  • Cancer as a genetic disease: definition of oncogenes and tumor suppressor genes.



Module:
N/D
Module:
N/D

Sustainability goals

  • Goal3
  • Goal4
  • Goal5
  • Academic year2026/2027
  • Degree program to which the course belongsImaging and Radiotherapy techniques - Course G - Roma Ospedale S. Spirito
  • Mandatory presenceNo
  • Languageita
  • CFU7 CFU, distributed among 4 integrated didactic modules
  • Total duration70 hours