Single channel

Chair (Coordinator) and Rapporteur: Alessandro Vitale

Module 1:

Activity type
Scienze biomediche
SSD
BIOS-07/A
Year
1st year
Semester
2nd semester
CFU
1
Hours distribution
10 classroom hours
Lecturers
CLAUDIA QUINTILIANI

Module 2:

Activity type
Scienze biomediche
SSD
BIOS-09/A
Year
1st year
Semester
2nd semester
CFU
1
Hours distribution
10 classroom hours
Lecturers
CATIA MAROCCO

Module 3:

Activity type
Scienze biomediche
SSD
BIOS-10/A
Year
1st year
Semester
2nd semester
CFU
2
Hours distribution
20 classroom hours
Lecturers
MICHELA CITTADINI

Module 4:

Activity type
Scienze biomediche
SSD
MEDS-03/A
Year
1st year
Semester
2nd semester
CFU
2
Hours distribution
20 classroom hours
Lecturers
Alessandro Vitale

Learning outcomes

By the end of the course, students are expected to have developed an in-depth understanding of the structure of eukaryotic and prokaryotic cells, including their morphological, functional, and metabolic features that determine their organization and interactions with the environment.
Furthermore, students should be able to demonstrate that they have acquired the theoretical knowledge and critical skills necessary to interpret biological phenomena from an evolutionary perspective, recognizing the mechanisms of adaptation, selection, and diversification that underlie the complexity of life.

Prerequisites

A solid understanding of the fundamental principles of General Biology, with a specific focus on the structural and functional organization of eukaryotic and prokaryotic cells, as well as on the main biochemical processes and metabolic reactions that regulate their vital activities.

Programme

Module:
BIOMOLECULES:
Carbohydrates
Lipids
Proteins
Nucleic acids
Hemoglobin and myoglobin
Enzymes
Vitamins
METABOLIC PATHWAYS
Glycolysis
Gluconeogenesis
Glycogen metabolism
Krebs cycle
Lipolysis and β-oxidation of fatty acids
Electron transport chain and oxidative phosphorylation
ATP and muscle contraction
Pentose phosphate pathway
Fatty acid biosynthesis
Amino acid catabolism
Urea cycle
Amino acid biosynthesis
Nitrogenous base metabolism


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Module:
MICROBIOLOGY
History, purpose and foundations of Microbiology
A) History of Microbiology
B) Concept of the living
C) Phylogeny of the living
D) Systematics, taxonomy and classification
D.1) Prokaryotes: structure, physiology and pathogenicity
D.2) Fungi: structure, physiology and pathogenicity
E) The non-living
E.1) Prions: molecular structure and pathogenicity
E.2) Viruses: structure and pathogenicity
F) Spillover, isolation, cultivation, observation, identification and study of microorganisms
F.1) Main pathogens for humans transmitted with food
F.2) The control of microorganisms and the damage they produce; microorganisms useful for humans
GThe importance of microbiology in the medical field
H) Infections (meaning, etiological agent, primary, prevention, fight against vehicles and vectors, remediation
environmental, vaccinations, therapy, infections of systems and organs

Books

Module:
Appunti di Biochimica per le lauree triennali CATANI, AVIGLIANO

Corso di Biochimica per le lauree triennali SAMAJA

I principi di Biochimica di Lehninger NELSON, COX

Biochimica BERG,STRYER

La Biochimica di Thomas M. Devlin G. D’ANDREA



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Texts adopted

R. Harvey, P. Champe, B. Fisher- The basis of Microbiology - ed. Zanichelli ISBN 978-88-08-17050-7
P. Cipriani, G. Dicuonzo - Elements of Microbiology and microbiology ed. Me Graw-Hill ISBN 978-88-386-36554
E. Lanciati - Principles of clinical microbiology - ed. Ambrosiana ISBN 978-88-4084409-4
M. Schaechter, J. Inghraham, F.Neidhardt Microbiology- ed. Zanichelli ISBN 978-88-08-06761-6
Lembo - Donalisio - Landolfo - Medical Microbiology - ed. Editions - ISBN 8879593811

Teacher slides

Bibliography

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Lessons mode

Frontal lesson

Frequency

Course attendance requirements
Attendance at the course "Cellular and Molecular Basis of Life" is mandatory for all enrolled students.
Attendance verification methods: Attendance verification is carried out through signature on attendance sheet in the classroom during class hours. The signature can be made:
• During the break between the first and second class hour
• During subsequent breaks between class hours
• At any time during scheduled breaks of the teaching day
Student responsibility: It is the student's responsibility to verify that they have correctly signed the attendance sheet at the established times and methods. Requests for retroactive attendance integration will not be accepted.

Exam mode

Assessment of learning will consist of written tests during the course, written examinations on the scheduled examination dates, and a final oral examination.

Example exam questions

The F₀ and F₁ units constitute:
a) ATP synthase
b) Pyruvate decarboxylase
c) Fatty acid synthase enzyme
d) Complex II of the electron transport chain
e) None of the other answers is correct

Which of the following statements about ATP is false?
a) It is a nucleotide
b) Its molecule contains an acid
c) Its molecule contains a nitrogenous base
d) Its molecule contains a sugar with five carbon atoms
e) Its molecule contains three phosphate groups

Which of the following bacteria shows colonies with a “Medusa head” appearance on solid media?
A. Mycobacterium tuberculosis
B. Vibrio cholerae
C. Corynebacterium diphtheriae
D. Bacillus anthracis
E. Clostridium tetani

Arguments

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Sustainability goals

  • Goal6
  • Goal12
  • Goal13
  • Academic year2026/2027
  • Degree program to which the course belongsEnvironment and Workplace Prevention Techniques - Course C - ASL Frosinone
  • Mandatory presenceNo
  • Languageita
  • CFU6 CFU, distributed among 4 integrated didactic modules
  • Total duration60 hours