PHYSIOPATHOLOGIC BASES OF DISEASES Single channel
Chair (Coordinator) and Rapporteur: FRANCESCA MEGIORNI
Module 1: Technical sciences of laboratory medicine
- Activity type
- Attività formative affini o integrative
- SSD
- MED/46
- Year
- N/D
- Semester
- N/D
- CFU
- 1
- Hours distribution
- 12 classroom hours
- Lecturers
- FRANCESCA MEGIORNI
Module 2: Pathology and pathophysiology
- Activity type
- Scienze biomediche
- SSD
- MED/04
- Year
- N/D
- Semester
- N/D
- CFU
- 2
- Hours distribution
- 24 classroom hours
- Lecturers
- AGOSTINA LONGO
Module 3: Microbiology
- Activity type
- Scienze biomediche
- SSD
- MED/07
- Year
- N/D
- Semester
- N/D
- CFU
- 2
- Hours distribution
- 24 classroom hours
- Lecturers
- Giovanna Giacchetti
Module 4: Anatomo pathology bases
- Activity type
- Scienze medico - chirurgiche
- SSD
- MED/08
- Year
- N/D
- Semester
- N/D
- CFU
- 1
- Hours distribution
- 12 classroom hours
- Lecturers
- GIANLUCA CIPOLLONI
Learning outcomes
Students will acquire knowledge of the etiopathogenic, morphological, and functional bases of major diseases, understanding the mechanisms that alter homeostasis and the main inflammatory, degenerative, and neoplastic processes. They will recognize the link between structural changes and clinical signs, understand the role of pathogens, and interpret key laboratory data relevant to nursing practice.
Prerequisites
The student must have acquired the basic notions, a good study methodology and adequate self-assessment skills. Basic knowledge of biology and biochemistry.
Programme
Module: Technical sciences of laboratory medicine
The analysis laboratory: pre-analytical, analytical, and post-analytical phases; concept of variability; quality control; reference ranges; predictive value; specificity and sensitivity
Basic and advanced techniques in laboratory medicine
Blood tests: clinical hematology, coagulation, glucose and lipid profile
Urine analysis
Stool analysis
Cardiac biomarkers
Tumor biomarkers
Liver biomarkers
Principles and applications of clinical chemistry in blood and other body fluids
Cardiac biomarkers
Tumor biomarkers
Epatic biomarkers
Module: Pathology and pathophysiology
Immune System
Acute Inflammation
Chronic Inflammation
Wound Healing
Type I Hypersensitivity
Overview of Autoimmune Diseases
Type I and Type II Diabetes Mellitus
Atherosclerosis
Module: Microbiology
- General bacteriology: Structure and growth of the
bacterial cell; Nutrition and cultivation of bacteria; Microbiological
diagnostic techniques; Pathogenicity and virulence of bacteria; Disinfection
and sterilization; Antibacterial chemotherapy.
- Special Bacteriology: Staphylococci; Streptococci; genera Bacillus and
Clostridium; Corynebacterium; listeria; mycobacteria; Enterobacteriaceae;
vibrio; Campylobacter; Helicobacter; Pseudomonas; Neisserie; Emofili;
Bordetella; Brucella; legionella; spirochetes; chlamydia; Mycoplasma.
- General virology: General properties of viruses and replication;
Pathogenesis of viral infections; Elements of antiviral chemotherapy;
Virological diagnostic techniques.
- Special virology: Herpesviridae, Adenoviridae, Papovaviridae,
Hepadnavirus. Orthomixoviridae, Paramixoviridae, Retroviridae,
Picornaviridae, Coronaviridae, Calciviridae, Astrovirus, Hepatitis virus.
- Overview of Mycology and Medical Protozoology.
Module: Anatomo pathology bases
Elements of histocitopathological technique
Histopathological examinations: incisional and excisional biopsies, surgical biopsy, cytological examinations.; examples.
Preservation of biological samples: chemical and physical fixation; intraoperative histological examination.; examples.
General Pathological Anatomy
Non-neoplastic alterations: hypertrophy, hyperplasia, atrophy, hypotrophy, aplasia, metaplasia; examples
Neoplasms: general characters: dysplasia, carcinoma in situ, invasive carcinoma; examples.
Benign and malignant, epithelial and non-epithelial tumors: classification; examples.
Grade and stage of neoplasia; examples.
Books
Module: Technical sciences of laboratory medicine
"Biochimica clinica essenziale. Dal laboratorio ai quadri di patologia clinica" di Elisabetta Albi, Tommaso Beccari, Samuela Cataldi. Ed. ZANICHELLI
Module: Pathology and pathophysiology
Patologia Generale ed Elementi di Fisiopatologia - M. PAROLA ET AL. - EDISES
ISBN 9788836230136
Module: Microbiology
Material distributed by the teachers.
Microbiology and Clinical Microbiology. R. Cevenini –V. Sambri. PICCIN
Module: Anatomo pathology bases
Anatomia Patologica - Le basi - Luigi Ruco, Aldo Scarpa. Edizioni UTE
Bibliography
Module: Technical sciences of laboratory medicine
Didactic material presented during the lessons will be provided to students or in electronic format. Useful material will also be recommended for further study.
Module: Pathology and pathophysiology
N/D
Module: Microbiology
N/D
Module: Anatomo pathology bases
N/D
Lessons mode
In person lectures.
Frequency
Mandatory.
Exam mode
Learning assessment will take place through a written test with multiple-choice and/or open-ended questions on the topics covered in class for the various modules of the integrated course. To pass the exam it is necessary to achieve a grade of not less than 18/30 in each module.
Example exam questions
What is meant by blood sugar; How is a complete blood count performed; Lipid profile; etc.
Arguments
Module: Technical sciences of laboratory medicine
- Lesson 1: The analysis laboratory: pre-analytical, analytical, and post-analytical phases; the concept of variability; quality control; reference ranges; predictive value; specificity and sensitivity. Basic and advanced techniques in laboratory medicine. Complete blood count and protein analysis.
- Lesson 2: Iron proteins. Coagulation and related tests. Glucose profile and diabetes.
- Lesson 3: Lipid profile and dyslipidemia. Cardiac biomarkers. Liver biomarkers.
- Lesson 4: Tumor biomarkers. Urinalysis. Stool analysis.
Module: Pathology and pathophysiology
- Immune system
- Acute inflammation
- Acute inflammation
- Wound healing
- Type I and type II diabetes
- Atherosclerosis
Module: Microbiology
- 8 lessons of 3 hours each explaining the various topics of the microbiology module program.
Module: Anatomo pathology bases
- 4 lessons of 3 hours each which explain the various topics of the module's program.
Sustainability goals
- Academic year2026/2027
- Degree program to which the course belongsNursing - Course S - ASL Rieti
- Mandatory presenceYes
- Languageita
- CFU6 CFU, distributed among 4 integrated didactic modules
- Total duration72 hours