INTEGRATED DIAGNOSTIC PATHS Single channel

Chair (Coordinator) and Rapporteur: MARA CIRONE

Module 1: ONCOLOGY

Activity type
Scienze interdisciplinari cliniche
SSD
MED/06
Year
N/D
Semester
N/D
CFU
1
Hours distribution
10 classroom hours
Lecturers
MARA CIRONE

Module 2: MEDICAL GENETICS

Activity type
Scienze e tecniche di laboratorio biomedico
SSD
MED/03
Year
N/D
Semester
N/D
CFU
1
Hours distribution
10 classroom hours
Lecturers
MARA CIRONE

Module 3: BLOOD DISEASES

Activity type
Scienze interdisciplinari cliniche
SSD
MED/15
Year
N/D
Semester
N/D
CFU
2
Hours distribution
20 classroom hours
Lecturers
SABINA CHIARETTI

Module 4: ENDOCRINOLOGY

Activity type
Scienze interdisciplinari cliniche
SSD
MED/13
Year
N/D
Semester
N/D
CFU
2
Hours distribution
20 classroom hours
Lecturers
EMILIA SBARDELLA

Learning outcomes

the student must acquire the basic knowledge of cellular degeneration, oncology and immunology

Prerequisites

the studente must have the bases to learn the lessons

Programme

Module: ONCOLOGY
cell proliferation and differentiation; hyperplasia, hypertrophy, metaplasia, anaplasia. Molecular basis of neoplastic transformation: oncogenes and tumor suppressor genes. Morphology of the neoplastic cell. Invasiveness and metastasis. Tumor promotion and progression. Apoptosis and angiogenesis in tumors. Chemical, physical and viral carcinogenesis. Antigens and tumor markers. Cancer classification criteria


Module: MEDICAL GENETICS
Genetic pathology:
Mode of transmission of hereditary diseases. Models of human genetic diseases. Gene Therapy. Non-hereditary congenital pathology.


Module: BLOOD DISEASES
basic knowledge of hematopoiesis.

correct interpretation of the blood count

principles of immunophenotype,

minimal residual disease concept

anemic

lymphomas, acute and chronic leukemias

myeloproliferative disorders



Module: ENDOCRINOLOGY


The Endocrinology course is divided into a first introductory part on the basic concepts necessary for the student to acquire both the terminological mastery and the general notions on the functioning of the system and a special part aimed at contestualizing the main diseases of the endocrine glands. The third part focuses on the basic concepts of hormonal dosages and on the different laboratory methods, aimed at developing the student's critical ability and the interpretation of laboratory data.
General introductory part on the structure and organization of the endocrine system concerning the endocrine glands (anatomy and distribution), hormones (synthesis, secretion and mechanism of action), receptors (nuclear and membrane), regulatory systems, integration of the endocrine system with the nervous system and with the immune system, concept of biological rhythm. Special section on the pathology of the hypothalamus and pituitary gland (acromegaly, gigantism, pituitary dwarfism); Thyroid (hypothyroidism, hyperthyroidism, thyroiditis); Parathyroid glands; Testicle and Ovary; Adrenal glands (hypoadrenocorticism, hypercorticadrenalism); Endocrine pancreas (Type 1 and 2 diabetes mellitus). Part on dosing methods.

A. General part
- The endocrine system
• The endocrine glands, hormones (synthesis, secretion and mechanism of action), receptors (nuclear and membrane), regulatory systems, integration of the endocrine system with the nervous system and the immune system, concept of biological rhythm
B. Special section
- Hypothalamus and pituitary: clinical and diagnostic tests
• Acromegaly, Gigantism
• Pituitary dwarfisms (GH deficiency)
• Hyperprolactinemia


- Thyroid: clinical and laboratory findings
• Hypothyroidism Hyperthyroidism Thyroiditis
• Parathyroid glands: clinical and laboratory findings
- Reproductive system: clinical and laboratory findings
• Male
• Female
- Adrenal glands: clinical and laboratory findings
• Hypoadrenalism (M. Di Addison)
• Hypercorticadrenalism (S. of Cushing)
• Hyperaldosteronism (primary and secondary)
• Congenital adrenocortical hyperplasia
• Endocrine hypertension
- Endocrine pancreas
• Type 1 and type 2 diabetes mellitus

C. Section on dosage methods

Books

Module: ONCOLOGY
elements of general pathology (Pontieri)


Module: MEDICAL GENETICS
elements of general pathology (Pontieri)


Module: BLOOD DISEASES
manuale di ematologie (corradini, Foa)


Module: ENDOCRINOLOGY
Guida allo studio dell'endocrinologia. M. D'Armiento, A. Lenzi. Società Editrice Universo. Didactic material provided by the teacher (in the form of PDF slides). Update guidelines on different topics.

Bibliography

Module: ONCOLOGY
N/D
Module: MEDICAL GENETICS
N/D
Module: BLOOD DISEASES
N/D
Module: ENDOCRINOLOGY
N/D

Lessons mode

classroom lessons

Frequency

the student must be present at the classroom lessons

Exam mode

oral examination

Example exam questions

viruses, tumors

Arguments

Module: ONCOLOGY

  • lezioni monosettimali di 2 ore



Module: MEDICAL GENETICS



Module: BLOOD DISEASES



Module: ENDOCRINOLOGY


Sustainability goals

  • Goal3
  • Goal5
  • Goal17
  • Academic year2026/2027
  • Degree program to which the course belongsBiomedical Laboratory techniques - Course A - Roma Azienda Policlinico Umberto I
  • Mandatory presenceNo
  • Languageita
  • CFU6 CFU, distributed among 4 integrated didactic modules
  • Total duration60 hours