Single channel
Chair (Coordinator) and Rapporteur: GIOVANNA GENTILE
Module 1:
- Activity type
- Scienze biomediche
- SSD
- MEDS-01/A
- Year
- 1st year
- Semester
- 1st semester
- CFU
- 1
- Hours distribution
- 8 classroom hours
- Lecturers
- MARIA PIANE
Module 2:
- Activity type
- Scienze biomediche
- SSD
- BIOS-07/A
- Year
- 1st year
- Semester
- 1st semester
- CFU
- 1
- Hours distribution
- 8 classroom hours
- Lecturers
- GIOVANNA GENTILE
Module 3:
- Activity type
- Scienze biomediche
- SSD
- BIOS-10/A
- Year
- 1st year
- Semester
- 1st semester
- CFU
- 1
- Hours distribution
- 8 classroom hours
- Lecturers
- CARLA CICCHINI
Module 4:
- Activity type
- Scienze umane e psicopedagogiche
- SSD
- PSIC-01/A
- Year
- 1st year
- Semester
- 1st semester
- CFU
- 2
- Hours distribution
- 16 classroom hours
- Lecturers
- FABIO FERLAZZO
Learning outcomes
The course aims to provide students with an integrated understanding of biology and psychology.
By the end of the course, students should be able to understand:
- the composition, organization, and integration of cells,
- biological macromolecules and cellular metabolism,
- the organization, expression, and transmission of genetic information and genetic mutations,
- the basic processes and psychological determinants of helping behavior.
This will enable them to understand physiological processes and pathologies, and to integrate biomedical knowledge with practical rehabilitation skills for patient care.
Prerequisites
To understand the course content and achieve the learning objectives, students must possess a basic knowledge of mathematics, chemistry, and biology, which they developed during their secondary school courses.
Programme
Module:
Aims of the Course:
Medical Genetics aims to provide the basic general concepts necessary to understand the mode of transmission of hereditary characteristics normal and pathological. At the end of the course the student will learn about the inheritance of some genetic disorders.
Program of Medical Genetics.
The structure and function of DNA
From DNA to protein: transcription, RNA splicing the genetic code, translation.
Human genome organization
Genes and mutations.
Origin of mutations. Point mutations, deletions, insertions, splicing mutations, dynamic mutations.
Structure and function of chromosomes.
Human chromosomes: the number, structure and function.
Chromosomal aberrations.
The normal and pathological human karyotype
Correlations between gametogenesis, meiosis, and segregation.
Family pedigrees: symbols
Concepts of inherited traits, gene, allele, locus
Mendel's laws and allelic interactions: dominance and recessive, phenotype and genotype
Family pedigrees: symbols
Classification of genetic disorders
Examples of hereditary monogenic Mendelian transmission:
autosomal dominant, autosomal recessive, X-linked recessive, X-linked dominant.
Non Mendelian inheritance
Module:
Composition, properties, and states of matter (Structure of the atom and nature of chemical bond)
Solutions.
Electrolytes and Oxidation-Reduction Reactions.
Acids and bases, pH, mention of Biological buffer systems.
Structure and function of biological molecules: carbohydrates, lipids, aminoacids, and proteins.
biological reactions and enzymes.
Metabolism: General principles. Mention of energetic metabolism and the role of ATP.
Mention of main metabolic pathways: glycolysis, Krebs cycle, oxidative phosphorylation, lactic acid fermentation, and alcoholic fermentation
Module:
The prokaryotic cell. The eukaryotic cell. Cellular organelles.
Cytoskeleton. Membranes. Cell-cell interaction. Cell signaling. Transport. Endocytosis. Exocytosis.
DNA structure. Replication, transcription, translation. RNA functions.
Mitosis. Meiosis. Cell cycle.
Mutations.
Module:
The course aims to introduce the beginning and development of scientific psychology, to deepen the basic processes and psychological determinants of helping behavior.
The main topics will be related to: Perception, Attention, Memory, Emotions, Executive functions, Reasoning and Decision-making.
At the end of the course the student will master the knowledge about the basic processes of general psychology, personality and cognitive and motivational determinants of helping behavior.
Students should be able to: identify the mental processes that determine the behavior of the helping behavior; critically examine the theories, to relate the processes investigated, the appropriate use of psychological terminology
Books
Module:
Biologia e Genetica N A. Campbell e J B. Reece:. Pearson
Elementi di biologia e genetica. William K. Purves, David Sadava, Gordon H. Orians, H. Craig Heller: Ed Zanichelli
Genetica umana e medica (Neri, Genuardi) Ed. Elsevier Masson
Links consigliati: Mendelian Inheritance in Man : http://www.ncbi.nlm.nih.gov/Omim/
Module:
- Samaja, Paroni “Chimica e Biochimica” Ed. Piccin
- Stefani, Taddei “Chimica, Biochimica e Biologia applicata” Zanichelli
- Bertoldi, Colombo ed altri, “Chimica e Biochimica” EdiSES
- Nelson-Cox I PRINCIPI DI BIOCHIMICA di Lehninger, Zanichelli
Module:
Suggested textbooks:
- A. Bevilacqua et al., Basi molecolari e cellulari della vita 2020 Piccin
- P. Bonaldo, C. Crisafulli, R. D’angelo et al., Elementi di Biologia e Genetica 2019 EdiSES
- David Sadava, David M. Hillis, H. Craig Heller, Sally D. Hacker Elementi di Biologia e Genetica 2019 Zanichelli
- Chiara Donati, Massimo Stefani, Niccolò Taddei Biologia e Genetica 2019 Zanichelli
- Solomon, Martin, Martin, Berg, Elementi di Biologia. 2017 EdiSES.
- P.J. Russell, P.E. Hertz, B. McMillan Elementi di Biologia Cellulare. 2016 EdiSES.
or to be defined in agreement with the teacher
Module:
P.Legrenzi, C. Papagno, C. Umilta' (2012). Psicologia Generale, Bologna: Il Mulino
Bibliography
Module:
Biologia e Genetica N A. Campbell e J B. Reece:. Pearson
Elementi di biologia e genetica. William K. Purves, David Sadava, Gordon H. Orians, H. Craig Heller: Ed Zanichelli
Genetica umana e medica (Neri, Genuardi) Ed. Elsevier Masson
Links consigliati: Mendelian Inheritance in Man : http://www.ncbi.nlm.nih.gov/Omim/
Module:
- Samaja, Paroni “Chimica e Biochimica” Ed. Piccin
- Stefani, Taddei “Chimica, Biochimica e Biologia applicata” Zanichelli
- Bertoldi, Colombo ed altri, “Chimica e Biochimica” EdiSES
- Nelson-Cox I PRINCIPI DI BIOCHIMICA di Lehninger, Zanichelli
Module:
- A. Bevilacqua et al., Basi molecolari e cellulari della vita 2020 Piccin
- P. Bonaldo, C. Crisafulli, R. D’angelo et al., Elementi di Biologia e Genetica 2019 EdiSES
- David Sadava, David M. Hillis, H. Craig Heller, Sally D. Hacker Elementi di Biologia e Genetica 2019 Zanichelli
- Chiara Donati, Massimo Stefani, Niccolò Taddei Biologia e Genetica 2019 Zanichelli
- Solomon, Martin, Martin, Berg, Elementi di Biologia. 2017 EdiSES.
- P.J. Russell, P.E. Hertz, B. McMillan Elementi di Biologia Cellulare. 2016 EdiSES.
Module:
P.Legrenzi, C. Papagno, C. Umilta' (2012). Psicologia Generale, Bologna: Il Mulino
Lessons mode
Module:
N/D
Module:
N/D
Module:
N/D
Module:
N/D
Frequency
Attendance is mandatory.
To be admitted to the exam, students must have a minimum attendance of 67%.
Exam mode
The exam grade will be the mathematical average of the grades obtained in the individual subjects of the course (Biology, Biochemistry, Genetics, Psychology).
For each subject, students will take a written exam with multiple-choice and/or open-ended questions. Students will pass the exam with a grade of 18/30 or higher.
Example exam questions
- Cosa sono gli isotopi?
- Come si definisce il pH di una soluzione?
- Secondo quanto proposto da Mendel, quanti alleli di uno stesso gene porta ciascun individuo?
- Qual è il tipo di RNA che fa "da ponte" tra il trascritto e la catena polipeptidica in allungamento?
- Quale delle seguenti strutture cerebrali svolge un ruolo importante nei processi di memoria?
Arguments
Module:
- Organization of the human genome Genes and gene mutations Origin of mutations: point mutations, deletions, insertions, splice-site mutations, dynamic mutations.Human chromosomes: number, structure, and function.
- Chromosomal abnormalities Normal and pathological human karyotypeRelationships among gametogenesis, meiosis, and segregation
- Mendelian inheritance Heritable trait, gene, allele, locusMendel’s laws: dominance and recessiveness; phenotype and genotype.Pedigree analysis: symbols and notation.
- Model of Transmission of Mendelian traits Classification of genetic diseasesExamples of monogenic disorders with Mendelian transmission: autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive. Non-Mendelian inheritance
Module:
- Lecture 1:
Atoms, Elements, Molecules, Chemical Bonds, and Chemical Reactions. Solutions
and Properties of Solutions. - Lecture 2: Water, pH, Acids, Bases, and Buffer Systems. Biological Macromolecules: Carbohydrates, Lipids.
- Lecture 3: Proteins – Structures and Functions. Hemoglobin – Enzymes – Enzyme Kinetics and Regulation of Enzyme Activity
- Lecture 4: Bioenergetics and Metabolism. Glycolysis – Krebs Cycle – Lactic Acid Fermentation – Oxidative Phosphorylation
Module:
- UD1:The prokaryotic cell. The eukaryotic cell. Cellular organelles.Cytoskeleton. Membranes. Cell-cell interaction. Cell signaling. Transport. Endocytosis. Exocytosis
- Unit 2: DNA structure. Replication, transcription, translation. RNA functions.Mutations.
- Unit 3:Mitosis. Meiosis. Cell cycle.
Module:
- Introduction. Perception
- Attention
- Memory
- Emotions
- Executive functions
Sustainability goals
- Academic year2026/2027
- Degree program to which the course belongsPodiatry - Roma Azienda Ospedaliera Sant’Andrea
- Mandatory presenceNo
- Languageita
- CFU5 CFU, distributed among 4 integrated didactic modules
- Total duration40 hours