Imaging and Radiotherapy techniques - Viterbo ASL Viterbo

Activity type

Scienze biomediche

SSD

MEDS-01/A

Year

1st year

Semester

1st semester

CFU

1

Hours distribution

8 classroom hours

Lecturers

Gloria Pessina

Activity type

Scienze biomediche

SSD

BIOS-10/A

Year

1st year

Semester

1st semester

CFU

2

Hours distribution

16 classroom hours

Lecturers

ERICA TRAMONTANA

Activity type

Scienze biomediche

SSD

BIOS-13/A

Year

N/D

Semester

N/D

CFU

1

Hours distribution

8 classroom hours

Lecturers

Activity type

Scienze biomediche

SSD

MEDS-02/A

Year

1st year

Semester

1st semester

CFU

2

Hours distribution

16 classroom hours

Lecturers

SALVATORE RAFFA
ANGELA LOMBARDI

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Training Objectives
At the end of the course the student must be able to know fundamental elements and biological mechanisms of life and higher organisms, specifically, of the human being, in order to obtain an optimal healthcare worker-patient interaction.


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No prerequisites


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Cellular theory. Organization of the prokaryotic and eukaryotic cell. Endosymbiotic theory. Chemical composition of the cell, structure and function of biological macromolecules (carbohydrates, proteins, lipids, nucleic acids). Exergonic and endergonic reactions. Enzymes and enzymatic catalysis.

The DNA. The structure of the double helix. Chromosomes, chromatin. DNA replication. The replication machinery. Notes on DNA repair. Notes on telomerase.

RNA. Transcription in prokaryotes. Transcription in eukaryotes. Maturation of eukaryotic mRNAs. The genetic code. Genetic mutations. tRNAs and ribosomes. Translation in prokaryotes and eukaryotes: initiation, elongation and termination. The control of gene expression in prokaryotes: the lac operon and the trp operon. The control of gene expression in eukaryotes: transcription factors, enhancers, regulation of chromatin structure, post-transcriptional and post-translational control.

Structure and properties of biological membranes: composition and fluidity of membranes. Cytoplasmic organelles: nucleus, Golgi apparatus, smooth and rough endoplasmic reticulum, ribosomes, mitochondria, lysosomes, peroxisomes. Protein sorting. Post-translational and co-translational transport. Vesicular trafficking: exocytosis and endocytosis. The cytoskeleton.

Cellular signaling. Classes of receptors. Signal transduction. Second messengers.

The cell cycle. Control of the cell cycle. Mitosis. Apoptosis. Oncogenes and tumor suppressors.
Sexual reproduction and meiosis.


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Elements of Biology- E. P. Solomon, C. E. Martin, D. W. Martin, L. R. Berg-VIII/2017-EdiSES

Elements of BIOLOGY and GENETICS - Raven-Johnson-Mason-Logos-Singer. Piccin Editore

Becker: The World of the Cell, Jeff Hardin, James P. Lodolce, Tenth edition. Pearson

Biochemistry and biology for the health professions, sec. Ed, R. Roberti, C. Antognelli, G. Alunni Bistocchi, V.N. Talesa, McGraw Hill

For those wishing to delve deeper into some topics, we recommend consulting:

The essentials of molecular biology of the B cell. Alberts, D. Bray, K. Hopkin, A. Johnson, J. Lewis, M. Raff, K. Roberts, P. Walter.- Fourth edition 2015, ZANICHELLI


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The teaching method can be carried out both traditionally and remotely depending on the work shifts.


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Attendance must be more than 50% of lessons to qualify for the exam.


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For the oral test on mastery of the topic covered.
For the written test, passing the questions.


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Transcription in prokaryotes.


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• Cell theory. Organization of the prokaryotic and eukaryotic cell. Endosymbiotic theory. Chemical composition of the cell, structure, and function of biological macromolecules (carbohydrates, proteins, lipids, nucleic acids). Exergonic and endergonic reactions. Enzymes and enzymatic catalysis.DNA. The structure of the double helix. Chromosomes, chromatin. DNA replication. The replication machinery. Notes on DNA repair. Notes on telomerase.
  • Books: Elements of Biology- E. P. Solomon, C. E. Martin, D. W. Martin, L. R. Berg-VIII/2017-EdiSESElements of BIOLOGY and GENETICS - Raven-Johnson-Mason-Logos-Singer. Piccin EditoreBecker: The World of the Cell, Jeff Hardin, James P. Lodolce, Tenth edition. PearsonBiochemistry and biology for the health professions, sec. Ed, R. Roberti, C. Antognelli, G. Alunni Bistocchi, V.N. Talesa, McGraw HillFor those wishing to delve deeper into some topics, we recommend consulting:The essentials of molecular biology of the B cell. Alberts, D. Bray, K. Hopkin, A. Johnson, J. Lewis, M. Raff, K. Roberts, P. Walter.- Fourth edition 2015, ZANICHELLI


• RNA. Transcription in prokaryotes. Transcription in eukaryotes. Maturation of eukaryotic mRNAs. The genetic code. Genetic mutations. tRNAs and ribosomes. Translation in prokaryotes and eukaryotes: initiation, elongation, and termination. Control of gene expression in prokaryotes: the lac operon and the trp operon. Control of gene expression in eukaryotes: transcription factors, enhancers, regulation of chromatin structure, post-transcriptional and post-translational control.


• Structure and properties of biological membranes: membrane composition and fluidity. Cytoplasmic organelles: nucleus, Golgi apparatus, smooth and rough endoplasmic reticulum, ribosomes, mitochondria, lysosomes, peroxisomes. Protein sorting. Post-translational and co-translational transport. Vesicular trafficking: exocytosis and endocytosis. The cytoskeleton.


• Cell signaling. Receptor classes. Signal transduction. Second messengers.The cell cycle. Control of the cell cycle. Mitosis. Apoptosis. Oncogenes and tumor suppressors.Sexual reproduction and meiosis.