Attendance

The aim of the course is to provide students with the necessary guidelines for the classification of the main haematological diseases. The principles of treatment and management of the onco-haematological patient will be illustrated. The course also aims to provide students with knowledge about the functioning of the hematopoietic organs and physiological control mechanisms. SYLLABUS Hematopoiesis. The hematopoietic stem cell and hematopoietic progenitors. (1 hour) Diagnostic tests in hematology: peripheral blood and bone marrow. (2 hour) Anemias: classification (2 hours) Platelet and coagulation disorders. (2 hour) Onco-hematology (8 hours) Definition of neoplasia. General features of the neoplastic cell. Integrated diagnostic pathway in onco-hematology:  Morphological examination  Flow cytometry  Cytogenetics and molecular genetics  Molecular investigations Definition and classification:  Acute myeloid and lymphoid leukemia  Chronic myeloproliferative neoplasms  Chronic lymphatic leukemia  Hodgkin's lymphoma, non-Hodgkin's lymphomas,  Monoclonal Gammopathies and Multiple Myeloma Stem cell transplantation: autologous and allogeneic. (1 hour)

To achieve a broader understanding of the course contents useful for the achievement of the learning objectives, it is essential that the student has acquired previous knowledge (basic notions) of cell biology and histology.

L’Ematologia di Mandelli - G. Avvisati, second edition (2019) ISBN: 978-88-299-2307-6; Piccin. Any other recently published hematology textbook can be used.

The course will take place through frontal and interactive lessons with the student for a total duration of 16 hours. Each meeting will develop one or more topics included in the program, with the support of iconographic material collected in PowerPoint files.

As reported in point 8 of the didactic regulations, "the attendance of frontal teaching activities (ADF) is compulsory".

The final exam will be held orally. The criteria useful for the evaluation will be: - knowledge and understanding of the topic; - use of appropriate terminology and language; - ability to analyze and synthesize.

Recent bibliography recommended during the lessons.

The course will take place through frontal and interactive lessons with the student for a total duration of 16 hours. Each meeting will develop one or more topics included in the program, with the support of iconographic material collected in PowerPoint files.