Speech and Language Therapy - Course A - Roma Azienda Policlinico Umberto I

Activity type

Scienze propedeutiche

SSD

PHYS-06/A

Year

1st year

Semester

1st semester

CFU

2

Hours distribution

20 classroom hours

Lecturers

MICHELA FRATINI

Activity type

Scienze biomediche

SSD

BIOS-07/A

Year

1st year

Semester

1st semester

CFU

2

Hours distribution

20 classroom hours

Lecturers

CARLO TRAVAGLINI ALLOCATELLI

Activity type

Scienze biomediche

SSD

BIOS-10/A

Year

1st year

Semester

1st semester

CFU

1

Hours distribution

10 classroom hours

Lecturers

CARLO TRAVAGLINI ALLOCATELLI

Activity type

Scienze biomediche

SSD

MEDS-01/A

Year

1st year

Semester

1st semester

CFU

1

Hours distribution

10 classroom hours

Lecturers

VIVIANA CAPUTO

Module:
N/D
Module:
Understanding the fundamental principles of biological chemistry, particularly the concepts of structure and function of biomolecules such as proteins, carbohydrates, lipids, and nucleic acids.
Familiarity with laboratory techniques used for biomolecule analysis, such as spectroscopy, chromatography, and PCR.
Understanding the biochemical processes involved in cellular energy production, such as glycolysis, the Krebs cycle, and oxidative phosphorylation.
Ability to apply acquired knowledge to understand and solve complex biochemical problems.
Capability to communicate basic concepts of biochemistry and their applications in biological contexts clearly and coherently.


Module:
Understand the applications of molecular biology in various sectors such as medicine, agriculture, environment, and industry.
Know the fundamental processes of DNA replication and transcription and protein synthesis.
Know the laboratory techniques used for genetic manipulation, such as cloning, PCR, and recombinant DNA technology.
Understand the impact of biotechnology and biotechnologies on living systems and society.
Be able to communicate the fundamental concepts of applied biology and their applications in various contexts clearly and coherently.


Module:
N/D

Module:
N/D
Module:
Necessary pre-requisites for a comprehension of the Course are a secondary education knowledge of Chemistry, Biology and Physics.


Module:
Necessary pre-requisites for a comprehension of the Course are a secondary education knowledge of Chemistry, Biology and Physics.


Module:
N/D

Module:
N/D
Module:
Chemical bonds, molecular architecture, acid-base reactions, redox reactions.
Biological macromolecules: carbohydrates, lipids, nucleic acids. Bioenergetics: principles of thermodynamics, high energy bonds, coupled reactions. Protein structure-function relationships (with specific examples). Allosteric proteins. Enzymes: mechanisms of catalysis and enzymatic regulation. Main metabolic pathways and their regulation.



Module:
Key aspects of molecular processes in prokaryotic and eukaryotic cells. Genes and genome organization. DNA replication. RNA transcription. Protein synthesis. Recombinant DNA methodologies and biotechnology.


Module:
N/D

Module:
N/D
Module:
Slides of the lessons available on the website of the Course.
Mason, Losos, Singer; vol. Biologia & Genetica e Biologia Molecolare - PICCIN
Stefani, Taddei; Chimica, Biochimica e Biologia applicata - ZANICHELLI



Module:
Slides of the lessons available on the website of the Course.
Mason, Losos, Singer; vol. Biologia & Genetica e Biologia Molecolare - PICCIN
Stefani, Taddei; Chimica, Biochimica e Biologia applicata - ZANICHELLI



Module:
N/D

Module:
N/D
Module:
N/D
Module:
N/D
Module:
N/D

Module:
N/D
Module:
Formal lessons: Programme topics will be discussed during the lessons.


Module:
Formal lessons: Programme topics will be discussed during the lessons.


Module:
N/D

Module:
N/D
Module:
Attendance mandatory


Module:
Attendance mandatory


Module:
N/D

Module:
N/D
Module:
The determination of the final evaluation will take into account:
1) the evaluation of the written test
2) the evaluation of the oral test


Module:
The determination of the final evaluation will take into account:
1) the evaluation of the written test
2) the evaluation of the oral test


Module:
N/D

Module:
N/D
Module:
questions concerning the program of the course



Module:
questions concerning the program of the course



Module:
N/D

Module:
N/D
Module:

• Teaching Unit 1. Chemical bonds, molecular architecture, acid-base reactions, redox reactions.
  Teaching Unit 2. Macromolecules of biological interest: carbohydrates, lipids, nucleic acids. Bioenergetics: thermodynamics, high-energy bonds, coupled reactions.
  Teaching Unit 3. Protein structure and function. Oxygen transport proteins. Allosteric proteins. Enzymes: catalysis and regulation mechanisms.
  Teaching Unit 4.
  Main metabolic pathways and their regulation. Bioenergetics.

• Unit 1. DNA Structure and Replication.
  Unit 2. Structures of Different Types of RNA and Transcription. Disrupted Genes and Splicing.
  Unit 3. The Ribosome and Protein Synthesis.
  Unit 4. Recombinant DNA Technologies and Biotechnology.

• - DNA: structure and function. Protein synthesis. Genes, genome, and genetic mutations. 2h


• - Transmission of inherited traits. Classification of genetic diseases. 2h


• - Examples of monogenic diseases. 1h


• - Human chromosomes. Karyotype. Chromosomal anomalies. Chromosomal disorders. 2h


• - Diagnosis of monogenic diseases and chromosomal disorders. 1h


• - Prenatal diagnosis of genetic diseases. 1h


• - Genetic counseling: indications, aims, and methods. 1h