INTEGRATED PATHOLOGY IV Single channel

Chair (Coordinator) and Rapporteur: ALICE DI ROCCO

Module 1: Rheumatology

Activity type
Clinica delle specialità medico-chirurgiche, Tirocini formativi e di orientamento
SSD
MED/16, MED/16
Year
5th year
Semester
1st semester
CFU
2
Hours distribution
12.5 classroom hours, 5 training hours, 20 others hours
Lecturers
ROSSANA SCRIVO

Module 2: INTERNAL MEDICINE

Activity type
Clinica generale medica e chirurgica
SSD
MED/09
Year
5th year
Semester
1st semester
CFU
2
Hours distribution
25 classroom hours
Lecturers
MILVIA CASATO
MARCELLA VISENTINI

Module 3: BLOOD DISEASES

Activity type
Clinica delle specialità medico-chirurgiche, Attività formative affini o integrative
SSD
MED/15, MED/15
Year
5th year
Semester
1st semester
CFU
2
Hours distribution
22 classroom hours, 3 training hours
Lecturers
ALICE DI ROCCO
MASSIMO BRECCIA

Objectives

General Teaching Objectives By the end of the course the student must:

Have acquired essential knowledge about the approach towards the rheumatologically sick patient, with particular reference to rheumatic pathologies and degenerative and phlogistic impression (systemic and non)

Have acquired essential knowledge about the diagnostic organization and therapeutic approach to the main pathologies of the immune system with particular reference to immunodeficiencies, auto-immune diseases and to vasculitis and allergopathologies.

Have acquired essential knowledge of the approach towards the hematological patient with particular reference to
anemias, onco-hematological pathologies and disorders of the hemostasis.

Diagnosis and therapy of the major immunological diseases, with special reference to immunodeficiencies (excluding HIV disease), autoimmune diseases, vasculitides and allergic diseases.
Diagnosis and therapy of the major hematologic diseases, with special reference to anemias, onco-hematologic diseases and disorders of hemostasis.
Diagnosis and therapy of the major rheumatologic diseases, with special reference to inflammatory disorders (systemic and non-systemic).

Learning outcomes

Module: Rheumatology
N/D
Module: INTERNAL MEDICINE
N/D
Module: BLOOD DISEASES
N/D

Prerequisites

Students are expected to have:
• A solid understanding of basic human anatomy, physiology, and biochemistry.
• Foundational knowledge of general pathology and mechanisms of inflammation.
• Basic principles of microbiology and immunology, including the immune response and its regulation.
• Preliminary notions of pharmacology, particularly regarding anti-inflammatory, immunosuppressive, and chemotherapeutic agents.
• Basic clinical skills in patient history taking, physical examination, and interpretation of routine laboratory tests

Programme

Module: Rheumatology
Pathophysiology of the musculoskeletal system and connective tissue.
Rheumatologic semiology.
Rheumatoid arthritis.
Spondyloarthritides: ankylosing spondylitis, psoriatic arthritis, reactive and enteropathic arthritis.
Connective tissue diseases (systemic lupus erythematosus, antiphospholipid syndrome, Sjögren’s syndrome, systemic sclerosis, polymyositis/dermatomyositis).
Vasculitides, IgG4-related disease (IgG4-RD).
Autoinflammatory diseases


Module: INTERNAL MEDICINE
N/D
Module: BLOOD DISEASES
N/D

Books

Module: Rheumatology
Harrison's Principles of Internal Medicine, 22nd Edition.


Module: INTERNAL MEDICINE
N/D
Module: BLOOD DISEASES
N/D

Bibliography

Module: Rheumatology
N/D
Module: INTERNAL MEDICINE
N/D
Module: BLOOD DISEASES
N/D

Lessons mode

Module: Rheumatology
N/D
Module: INTERNAL MEDICINE
N/D
Module: BLOOD DISEASES
N/D

Frequency

Module: Rheumatology
N/D
Module: INTERNAL MEDICINE
N/D
Module: BLOOD DISEASES
N/D

Exam mode

Module: Rheumatology
N/D
Module: INTERNAL MEDICINE
N/D
Module: BLOOD DISEASES
N/D

Example exam questions

Module: Rheumatology
N/D
Module: INTERNAL MEDICINE
N/D
Module: BLOOD DISEASES
N/D

Arguments

Module: Rheumatology

  • Introduction to rheumatological diseases. Pathogenesis of rheumatoid arthritis.
    • Books: Harrison's Principles of Internal Medicine, 22nd Edition.

  • Clinical aspects and treatment of rheumatoid arthritis.
    • Books: Harrison's Principles of Internal Medicine, 22nd Edition.

  • General overview of spondyloarthritides. Axial spondyloarthritides.
    • Books: Harrison's Principles of Internal Medicine, 22nd Edition.

  • Peripheral spondyloarthritides (psoriatic arthritis, reactive arthritis).
    • Books: Harrison's Principles of Internal Medicine, 22nd Edition.

  • Pathogenesis and cutaneous and musculoskeletal manifestations of systemic lupus erythematosus.
    • Books: Harrison's Principles of Internal Medicine, 22nd Edition.

  • Visceral involvement and therapy of systemic lupus erythematosus.
    • Books: Harrison's Principles of Internal Medicine, 22nd Edition.

  • Antiphospholipid antibody syndrome.
    • Books: Harrison's Principles of Internal Medicine, 22nd Edition.

  • Autoinflammatory diseases. Still's disease. VEXAS.
    • Books: Harrison's Principles of Internal Medicine, 22nd Edition.

  • IgG4-related disease.
    • Books: Harrison's Principles of Internal Medicine, 22nd Edition.



Module: INTERNAL MEDICINE
N/D
Module: BLOOD DISEASES
N/D

  • Academic year2026/2027
  • Degree program to which the course belongsMedicine and Surgery "A" - Roma Azienda Policlinico Umberto I
  • Languageita
  • CFU6 CFU, distributed among 3 integrated didactic modules
  • Total duration87.5 hours