Medicine and Surgery "E" - Pontine Campus

MARZIA ARESE
MARZIA ARESE
FRANCESCO FIORENTINO
FRANCESCO FIORENTINO

Based on the attachments to Ministerial Decree no. 418 of May 30, 2025, the syllabus for this course is uniform nationwide and has the following general objectives:

To provide the basis for understanding the fundamental laws governing matter and its transformations, with particular attention to biological phenomena at the atomic and molecular level, in relation to biomedical applications.

Learning outcomes in accordance with Ministerial Decree No. 418 of May 30, 2025, Syllabus_CHEMISTRY AND PREPARATORY BIOCHEMISTRY.
https://www.mur.gov.it/it/atti-e-normativa/decreto-ministeriale-n-418-del-30-05-2025

In compliance with Ministerial Decree No. 418, Syllabus_CHEMISTRY AND PREPARATORY BIOCHEMISTRY:
Knowledge of mathematics, physics, chemistry, and biology is required that meets the
preparation standards promoted by educational institutions that organize educational and teaching activities consistent with
the national guidelines for high schools and the guidelines for technical and vocational schools.

As described in DM 704 dated may 29 2026 Syllabus_CHIMICA E PROPEDEUTICA BIOCHIMICA:
1. Atomic structure, chemical bonds, states of matter, and thermodynamics of open systems. (Teaching commitment assessed in 1 credit)
2. Mixtures, solutions, and the colligative properties of solutions (Teaching commitment assessed in 1 credit)
3. Chemical reactions in living organisms: general characteristics, kinetics, and chemical equilibrium. (Teaching commitment assessed in 0.5 credit)
4. Acids, bases, salts, pH, buffer solutions; oxidation-reduction reactions and electrochemistry (Teaching commitment assessed in 1 credit)
5. Properties of carbon and reactivity of organic compounds, hydrocarbons, alkyl halides, aromatic hydrocarbons, and derivatives (Teaching commitment assessed in 0.5 credit)
6. Functional groups and isomers: alcohols, phenols, ethers, thiols, and thioethers; aldehydes and ketones; Carboxylic acids and derivatives, amines and amides (teaching commitment assessed in CFU = 1) Describe and
7. Amino acids and proteins, carbohydrates, lipids, nucleotides, polynucleotides and nucleic acids (teaching commitment assessed in CFU = 1)

- FA Bettelheim et al; Chimica e Propedeutica biochimica, Edises. (english language editionedition: Introduction to General, Organic and Biochemistry, FA Bettelheim et al., editor: Cengage Learning)
- T Bellini; Chimica Medica e Propedeutica Biochimica, Zanichelli.
- L Binaglia & B Giardina; Chimica e Propedeutica Biochimica, McGrawHill.
- KJ Denniston et al; Chimica Generale, Chimica Organica, Propedeutica Biochimica, McGrawHill. (english language edition: General, Organic and Biochemistry by Denniston et al. etitor: McGraw-Hill)
- S. Marini et al; Chimica e Propedeutica Biochimica, Piccin.

In-person and online lectures as described in D.M. No. 418, Syllabus_CHIMICA E PROPEDEUTICA BIOCHIMICA, on the theoretical concepts and laws described in the program, along with in-class exercises to monitor the progression of acquired knowledge and skills.
detailed lesson skedule at: https://www.uniroma1.it/sites/default/files/field_file_allegati/orariochimica_polorosa.pdf

mandatory with attendance tracking (by cineca)
both in-person class and online.

in compliance with Ministerial Decree No. 418 of 05/30/2025, Syllabus_CHEMISTRY AND PROPAEDEUTIC BIOCHEMISTRY.

- What is the volume occupied by 88 g of CO2 at a temperature value of 273°K and at a pressure value of 760 mmHg?
A) 44,8 L
B) 4,48 L
C) 2 L
D) 448 ml

- By adding 0.5 L of 0.1M fructose solution to 0.5 L of 0.1M aqueous acetic acid solution results in:
A) a decrease in the solution osmolarity
B) the formation of a buffer system
C) a lowering of the freezing point
D) an increase in the pH

- If 0.05 moles of calcium hydroxide are mixed to a 0.1 M solution of a weak monoprotic acid HA (Ka = 10-3; V = 1 liter). The pH of the solution becomes:
A) >7 due to the formation of a basic salt
B) strongly basic due to the excess of hydroxide ions
C) determined using the Henderson Hasselbach formula
D) acidic

• Atomic structure, isothopes, RMN
  • Books: see textbook section (TESTI)


• Radioisotopes; periodic table of elements
  • Books: see textbook section (TESTI)


• further lessons scheduled as in syllabus (D.M. 704 del 29 maggio 2026)