Medicine and Surgery "F"

Activity type

Medicina di laboratorio e diagnostica integrata

SSD

BIO/12

Year

N/D

Semester

N/D

CFU

1

Hours distribution

13 classroom hours

Lecturers

ANDREA BELLELLI

Activity type

Patologia generale e molecolare, immunopatologia, fisiopatologia generale, microbiologia e parassitologia

SSD

MED/07

Year

N/D

Semester

N/D

CFU

2

Hours distribution

25 classroom hours

Lecturers

GUIDO ANTONELLI

Activity type

Formazione clinica interdisciplinare e medicina basata sulle evidenze

SSD

MED/46

Year

N/D

Semester

N/D

CFU

1

Hours distribution

13 classroom hours

Lecturers

ANTONIO ANGELONI

Activity type

Tirocini formativi e di orientamento

SSD

MED/46

Year

N/D

Semester

N/D

CFU

1

Hours distribution

25 training hours

Lecturers

Activity type

Medicina di laboratorio e diagnostica integrata

SSD

MED/05

Year

N/D

Semester

N/D

CFU

3

Hours distribution

38 classroom hours

Lecturers

Activity type

Medicina di laboratorio e diagnostica integrata

SSD

BIO/12

Year

N/D

Semester

N/D

CFU

2

Hours distribution

25 classroom hours

Lecturers

Activity type

Tirocini formativi e di orientamento

SSD

VET/06

Year

N/D

Semester

N/D

CFU

1

Hours distribution

25 others hours

Lecturers

DAVID MODIANO

Learning outcomes:
At the end of the course, the student must know:
• Direct and indirect microbiological methods
• Optimal procedures to collect the biological specimens from a patient and their conservation
• Analytical procedures to isolate and identify extracellular pathogens as well as facultative and obligate intracellular microorganisms
• Microbiological analysis of urine, liquor, blood, amniotic fluid, sputum, central venous catheters, prosthesis, medical devices pharyngeal, cervical, vaginal and rectal swabs
• Classical and innovative microbiological methods to detect bacteria adherent and in biofilm
• Host-parasite interaction with particular attention to inflammatory and infectious phenomena
• Homeostasis of iron, infection and inflammation

Module: Laboratory Medicine I - BIO 12
N/D
Module: Laboratory Medicine I - MED 07
N/D
Module: Laboratory Medicine I - MED 46
N/D
Module: Laboratory Medicine I - VET 06
N/D
Module: Laboratory Medicine II - MED 05
N/D
Module: Laboratory Medicine II - BIO 12
N/D
Module: Laboratory Medicine II - MED 46
N/D

Module: Laboratory Medicine I - BIO 12
Knowledge of Chemistry, Biochemistry, and Microbiology is required.


Module: Laboratory Medicine I - MED 07
Requirements:
An intermediate level knowledge of general chemistry, organic chemistry and biochemistry is required..



Module: Laboratory Medicine I - MED 46
Requirements:
An intermediate level knowledge of general chemistry, organic chemistry and biochemistry is required..



Module: Laboratory Medicine I - VET 06
N/D
Module: Laboratory Medicine II - MED 05
N/D
Module: Laboratory Medicine II - BIO 12
N/D
Module: Laboratory Medicine II - MED 46
Requirements:
An intermediate level knowledge of general chemistry, organic chemistry and biochemistry is required..

Module: Laboratory Medicine I - BIO 12
Contents:
Theory of measurement and the concepts of experimental error, precision and accuracy
Applications of the theory to the measurements of Laboratory Medicine: interindividual variability, pathological deviations from the average values, false positives, false negatives, specificity and sensitivity of the tests. Principles of clinical reasoning.
Specimen collection for adult and fetal samples. Biological fluids: blood, urine cerebral-spinal fluid, amniotic fluid.
Main analytical methods used in Clinical Biochemistry and Molecular Biology: potentiometry, electrophoresis, chromatography, immunological methods, DNA sequencing and PCR
Clinical Toxicology: principal analytes and finality of their measurements. Analysis and levels of drugs more often causing over dosage, recreational drug, and environmental and professional poisons
Clinical Biochemistry of blood clotting and its disturbances: hemostasis and thrombosis
Clinical Biochemistry of anemias, hemoglobinopathies and thalassemia.
The hemocytometric analysis
Transfusion medicine; blood groups.
Histocompatibility testing and transplantation.
Clinical laboratory analyses for parasitology: Blood And Tissue Protozoa. Blood Trematodes.
Intestinal Protozoa. Intestinal And Tissue Cestodes. Intestinal Nematodes.
Molecular And Immunological Diagnosis Of Parasitic Infections.
Microbial Zoonoses. Protozoa Zoonoses.
Clinical laboratory analyses for bacterial and viral diseases. The microbes and the relationship with the host.
Diagnosis of infection and assesment of host defense mechanism.
Basic Mechanisms of drug resistance and spread or resistant microbes.
The chronic infections and viral hepatitis.
Upper and lower respiratory tract infections.
Sexually transmitted infections. Urinary infections.
Obstetric and perinatal infections.
Central nervous system. Infections of the skin, soft tissue, eye. Gastrointestinal infections.
The zoonoses.
Infections in the compromised host. Noscomial infections.


Module: Laboratory Medicine I - MED 07
Contents:
● Vaccination and chemotherapy in the control of infectious diseases.
● Methods of diagnosis of infectious diseases: direct and indirect analytical methods
● Procedures to collect the biological specimens from a patient and their conservation
● Analytical procedures for the search for pathogenic microorganisms in the different biological samples
● The Clinical Microbiology laboratory for address the infections in the various body districts



Module: Laboratory Medicine I - MED 46
Contents:
Newborn screening for hereditary metabolic diseases. Screening for the most common tumor pathologies. Blood count test.


Module: Laboratory Medicine I - VET 06
N/D
Module: Laboratory Medicine II - MED 05
N/D
Module: Laboratory Medicine II - BIO 12
N/D
Module: Laboratory Medicine II - MED 46
Contents:
Biological cycles and diagnosis of main parasitic infections caused by protozoa and helminths: intestinal (Amebiasis, Giardiasis, Cryptosporidiosis, Taeniasis, Ascaridiosis, Ankylostomiasis); uro-genital (Trichomoniasis); blood and tissues (Malaria, Leishmaniasis, Trypanosomiasis, Toxoplasmosis, Echinococcosis, Schistosomiasis).

Module: Laboratory Medicine I - BIO 12
Suggested textbooks:
Michael Laposata: Laboratory Medicine: The Diagnosis of Disease in the Clinical Laboratory (LANGE Basic Science)
Additional material is available on the website of the course: http://biochimica.bio.uniroma1.it/didattica/bellelli5.htm


Module: Laboratory Medicine I - MED 07
Suggested textbooks:
Patricia M. Tille - Bailey & Scott's Diagnostic Microbiology, 14th Edition Elsevier – 13 gennaio 2017



Module: Laboratory Medicine I - MED 46
Suggested textbooks:
Michael Laposata: Laboratory Medicine: The Diagnosis of Disease in the Clinical Laboratory (LANGE Basic Science)



Module: Laboratory Medicine I - VET 06
N/D
Module: Laboratory Medicine II - MED 05
N/D
Module: Laboratory Medicine II - BIO 12
N/D
Module: Laboratory Medicine II - MED 46
Suggested textbooks:
Michael Laposata: Laboratory Medicine: The Diagnosis of Disease in the Clinical Laboratory (LANGE Basic Science)

Module: Laboratory Medicine I - BIO 12
N/D
Module: Laboratory Medicine I - MED 07
N/D
Module: Laboratory Medicine I - MED 46
N/D
Module: Laboratory Medicine I - VET 06
N/D
Module: Laboratory Medicine II - MED 05
N/D
Module: Laboratory Medicine II - BIO 12
N/D
Module: Laboratory Medicine II - MED 46
N/D

Module: Laboratory Medicine I - BIO 12
Classroom lectures and seminars


Module: Laboratory Medicine I - MED 07
N/D
Module: Laboratory Medicine I - MED 46
N/D
Module: Laboratory Medicine I - VET 06
N/D
Module: Laboratory Medicine II - MED 05
N/D
Module: Laboratory Medicine II - BIO 12
N/D
Module: Laboratory Medicine II - MED 46
N/D

Module: Laboratory Medicine I - BIO 12
Attendance is compulsory for at least 67% of the total lectures.


Module: Laboratory Medicine I - MED 07
Compulsory


Module: Laboratory Medicine I - MED 46
Compulsory in presence


Module: Laboratory Medicine I - VET 06
N/D
Module: Laboratory Medicine II - MED 05
N/D
Module: Laboratory Medicine II - BIO 12
N/D
Module: Laboratory Medicine II - MED 46
Compulsory in presence

Module: Laboratory Medicine I - BIO 12
Oral examination. It is possible to take an ongoing examination, only at the end of the first semester (February session). The students are required to register to the exam on Infostud. The date indicated on Infostud is the first day of a period (usually a week) where the exam can take place; the effective location, date and time of the exam are communicated via Infostud at the end of the registration period. It is possible that the exam is delayed by a few days, with respect to the date indicated on Infostud, due to previously unforeseen duties of the teachers.


Module: Laboratory Medicine I - MED 07
The final examination is an interview with the candidate and covers the whole program of the Course.



Module: Laboratory Medicine I - MED 46
Evaluation methods:
The final examination is an interview with the candidate and covers the whole program of the Course.



Module: Laboratory Medicine I - VET 06
N/D
Module: Laboratory Medicine II - MED 05
N/D
Module: Laboratory Medicine II - BIO 12
N/D
Module: Laboratory Medicine II - MED 46
Evaluation methods:
The final examination is an interview with the candidate and covers the whole program of the Course.

Module: Laboratory Medicine I - BIO 12
How does Bayes statistical formula apply to laboratory medicine and medical diagnosis?
Illustrate the principal defects of coagulation
Explain the laboratory methods for the measurement of electrolytes
Describe the technique of electrophoresis; explain the electrophoretic profile of human serum
Discuss the differential diagnosis of anemias


Module: Laboratory Medicine I - MED 07
N/D
Module: Laboratory Medicine I - MED 46
N/D
Module: Laboratory Medicine I - VET 06
N/D
Module: Laboratory Medicine II - MED 05
N/D
Module: Laboratory Medicine II - BIO 12
N/D
Module: Laboratory Medicine II - MED 46
N/D

Module: Laboratory Medicine I - BIO 12

• see link: https://www.andreabellelli.it/html/didattica/Fcourse/LabMedSchedule1semester2025_26.htm

• see link: https://www.andreabellelli.it/html/didattica/Fcourse/LabMedSchedule1semester2025_26.htm

• see link: https://www.andreabellelli.it/html/didattica/Fcourse/LabMedSchedule1semester2025_26.htm

• see link: https://www.andreabellelli.it/html/didattica/Fcourse/LabMedSchedule1semester2025_26.htm