INTEGRATED PATHOLOGY III DISEASES OF THE DIGESTIVE SYSTEM ENDOCRINE SYSTEM AND METABOLISM Single channel
Chair (Coordinator) and Rapporteur: ILARIA BARCHETTA
Module 1: GASTROENTEROLOGY
- Activity type
- Clinica delle specialità medico-chirurgiche, Tirocini formativi e di orientamento
- SSD
- MED/12, MED/12
- Year
- 4th year
- Semester
- 2nd semester
- CFU
- 3
- Hours distribution
- 25 classroom hours, 25 others hours
- Lecturers
- CAROLA SEVERI
FLAMINIA FERRI
Module 2: GENERAL SURGERY DIGESTIVE SYSTEM
- Activity type
- Clinica generale medica e chirurgica, Tirocini formativi e di orientamento
- SSD
- MED/18, MED/18
- Year
- 4th year
- Semester
- 2nd semester
- CFU
- 2
- Hours distribution
- 12.5 classroom hours, 25 others hours
- Lecturers
- MICHELANGELO MICCINI
DANIELE CROCETTI
ALESSANDRO COPPOLA
Module 3: ENDOCRINOLOGY
- Activity type
- Formazione clinica interdisciplinare e medicina basata sulle evidenze
- SSD
- MED/05
- Year
- 4th year
- Semester
- 2nd semester
- CFU
- 1
- Hours distribution
- 12.5 classroom hours
- Lecturers
- DONATELLA PAOLI
Module 4: GENERAL SURGERY (ENDOCRINOLOGICAL SURGERY
- Activity type
- Clinica generale medica e chirurgica
- SSD
- MED/18
- Year
- 4th year
- Semester
- 2nd semester
- CFU
- 1
- Hours distribution
- 12.5 classroom hours
- Lecturers
- MARCO BONONI
Module 5: CLINICAL PATHOLOGY
- Activity type
- Clinica delle specialità medico-chirurgiche, Discipline ostetrico-ginecologiche, medicina della riproduzione e sessuologia medica, Fisiopatologia, metodologia clinica, propedeutica clinica e sistematica medico-chirurgica, Tirocini formativi e di orientamento
- SSD
- MED/13, MED/13, MED/13, MED/13
- Year
- 4th year
- Semester
- 2nd semester
- CFU
- 5
- Hours distribution
- 50 classroom hours, 25 others hours
- Lecturers
- FRANCESCO LOMBARDO
CARLA LUBRANO
FRANCESCO ROMANELLI
ILARIA BARCHETTA
Objectives
At the end of the course the student must: be able to critically evaluate and correlate clinical symptoms / signs and functional alterations with the main gastrointestinal and endocrine pathologies; be able to do an anamnesis and an objective examination of the gastroenterological and endocrinological patient; be aware of the epidemiology and socio-economic impact of the main gastrointestinal and endocrine diseases.
Learning outcomes
At the end of the course, students will be able to:
Critically assess and correlate clinical signs, symptoms, and functional alterations with the main gastrointestinal and endocrine diseases.
Understand the underlying pathophysiological mechanisms and recognize the principal clinical presentations.
Perform a complete medical history and physical examination of patients with gastrointestinal and endocrine disorders.
Integrate clinical, laboratory, and instrumental data to support diagnostic reasoning and therapeutic decision-making.
Demonstrate knowledge of the general principles of pharmacological and non-pharmacological treatment strategies for major gastrointestinal and endocrine diseases.
Evaluate the epidemiological and socio-economic impact of relevant diseases and their implications for clinical practice.
Communicate effectively with patients and healthcare professionals.
Independently update their knowledge based on national and international diagnostic and therapeutic guidelines.
Prerequisites
Yearly/Cultural prerequisites. Basic knowledge of anatomy, physiology, and biochemistry of the gastrointestinal and endocrine systems, as well as fundamental understanding of general pathology and medical semeiotics, which are essential for interpreting the pathophysiological and clinical mechanisms discussed during the course.
Programme
Module: GASTROENTEROLOGY
Disorders of the gut-brain interactions; Esophageal motor disorders; Gastro-esophageal reflux disease and relative complications; Gastroduodenal Diseases (dyspepsia, acute and chronic gastritis, peptic ulcer and Helicobacter pylori infection); Celiac disease and food intolerances; Inflammatory bowel diseases and relative complications; Diverticular Disease; Acute and chronic pancreatitis; Acute and chronic liver disease of infectious, metabolic, iatrogenic or autoimmune etiology; Cholestatic diseases; Multiple endocrine syndromes and neuroendocrine tumors of the gastrointestinal tract.
Professionalizing activities: Clinical history and examination of gastroenterological patient; Problem-solving activities in out-patients with gastrointestinal diseases.
Module: GENERAL SURGERY DIGESTIVE SYSTEM
Peritonitic and traumatic acute abdomen
Intestinal obstructions
Upper and lower gastrointestinal bleeding
Management of stomas and open abdomen
Intestinal perforations
Intestinal ischemia
Management of thoracic and abdominal trauma
Pneumothorax
Module: ENDOCRINOLOGY
Diseases of the hypothalamic–pituitary axis; dyslipidemias and metabolic syndrome; diabetes mellitus (classification, pathogenesis, diagnosis, and clinical presentation); acute and chronic complications of diabetes and new pharmacological treatments; hirsutism; hypo- and hyperthyroidism; dietary aspects of endocrine diseases; hypo- and hyperparathyroidism; parathyroid surgery and surgically relevant hyperparathyroidism; follicular thyroid carcinomas; medullary thyroid carcinoma; hypo- and hyperadrenalism; endocrine hypertension; hypogonadism and andropause; puberty and gynecomastia; erectile dysfunction; osteoporosis; hypoglycemic syndromes; obesity and underweight; endocrine disruptors; transgender health (endocrine aspects of gender incongruence).
The course includes presentation and discussion of clinical cases in class and hands-on professional training activities, aimed at deepening and practicing topics relevant to the final examination, with a particular focus on the correlation between pathophysiological, diagnostic, and therapeutic aspects.
Module: GENERAL SURGERY (ENDOCRINOLOGICAL SURGERY
The thyroid: Hypothyroidism, Hyperthyroidism, Nontoxic goiter, Thyroiditis, Thyroid cancer
Module: CLINICAL PATHOLOGY
Diseases of the hypothalamic–pituitary axis; dyslipidemias and metabolic syndrome; diabetes mellitus (classification, pathogenesis, diagnosis, and clinical presentation); acute and chronic complications of diabetes and new pharmacological treatments; hirsutism; hypo- and hyperthyroidism; dietary aspects of endocrine diseases; hypo- and hyperparathyroidism; parathyroid surgery and surgically relevant hyperparathyroidism; follicular thyroid carcinomas; medullary thyroid carcinoma; hypo- and hyperadrenalism; endocrine hypertension; hypogonadism and andropause; puberty and gynecomastia; erectile dysfunction; osteoporosis; hypoglycemic syndromes; obesity and underweight; endocrine disruptors; transgender health (endocrine aspects of gender incongruence).
The course includes presentation and discussion of clinical cases in class and hands-on professional training activities, aimed at deepening and practicing topics relevant to the final examination, with a particular focus on the correlation between pathophysiological, diagnostic, and therapeutic aspects.
Books
Module: GASTROENTEROLOGY
- DIGESTIVE DISEASES Edition 2022-2025 on behalf of UNIGASTRO, Ed: EDRA (2022)
Module: GENERAL SURGERY DIGESTIVE SYSTEM
Minerva Chirurgia generale. Metodologia, patologia, clinica chirurgica. Con CD-ROM Copertina flessibile – 1 novembre 2008 di Rocco Bellantone, Giorgio De Toma, Marco Montorsi
Dionigi : Chirurgia . Basi teoriche e Chirurgia generale - Chirurgia specialistica ( Opera in 2 Volumi )
di Dionigi - Ansaloni - Bignami - Boni - Castelnuovo - D' Ugo - AAVV • 2022
Manuale di chirurgia - di Jones • 2025- Francesca Delfino Editore
Module: ENDOCRINOLOGY
Title: Manuale di Endocrinologia, Authors: Lenzi - Scuole Romane di Endocrinologia, Editor: Carocci
Module: GENERAL SURGERY (ENDOCRINOLOGICAL SURGERY
- Sabiston Jr Textbook of Surgery
- Italian consensus for the classification and reporting of thyroid cytology. Nardi F, et al. J Endocrinol Invest. 2014. PMID: 24789536
- Italian consensus on diagnosis and treatment of differentiated thyroid cancer: joint statements of six Italian societies.Pacini F, Basolo F, Bellantone R, Boni G, Cannizzaro MA, De Palma M, Durante C, Elisei R, Fadda G, Frasoldati A, Fugazzola L, Guglielmi R, Lombardi CP, Miccoli P, Papini E, Pellegriti G, Pezzullo L, Pontecorvi A, Salvatori M, Seregni E, Vitti P.J Endocrinol Invest. 2018 Jul;41(7):849-876. doi: 10.1007/s40618-018-0884-2. Epub 2018 May 4. PMID: 29729004
- The American Association of Endocrine Surgeons Guidelines for the Definitive Surgical Management of Thyroid Disease in Adults.Patel KN, Yip L, Lubitz CC, Grubbs EG, Miller BS, Shen W, Angelos P, Chen H, Doherty GM, Fahey TJ 3rd, Kebebew E, Livolsi VA, Perrier ND, Sipos JA, Sosa JA, Steward D, Tufano RP, McHenry CR, Carty SE.Ann Surg. 2020 Mar;271(3):e21-e93. doi: 10.1097/SLA.0000000000003580. PMID: 32079830
Module: CLINICAL PATHOLOGY
Title: Manuale di Endocrinologia, Authors: Lenzi - Scuole Romane di Endocrinologia, Editor: Carocci
Bibliography
Module: GASTROENTEROLOGY
N/D
Module: GENERAL SURGERY DIGESTIVE SYSTEM
N/D
Module: ENDOCRINOLOGY
N/D
Module: GENERAL SURGERY (ENDOCRINOLOGICAL SURGERY
N/D
Module: CLINICAL PATHOLOGY
N/D
Lessons mode
The teaching activities shall be conducted through classroom lectures and through practical and professional training within the Endocrinology, Gastroenterology, and Surgery services. Attendance at both lectures and practical activities is mandatory.
Frequency
Attendance at both lectures and professional practical activities is mandatory and represents a necessary requirement for admission to the final examination.
Exam mode
The examination will be conducted in person and consists of two oral assessments, covering the module in Endocrinology / Endocrine Surgery and the module in Gastroenterology / Abdominal Surgery. The final grade will be calculated as the average of the marks obtained in the two assessments.
Example exam questions
During the oral examinations, candidates may be required to discuss representative clinical scenarios, to outline the principal diagnostic and therapeutic pathways, and to provide a critical appraisal of the indications and contraindications for surgical and medical treatments in the respective fields.
Further areas of assessment may include the underlying pathophysiological mechanisms of major endocrine and gastroenterological disorders, as well as the ability to integrate clinical and surgical knowledge in the comprehensive management of the patient.
Arguments
Module: GASTROENTEROLOGY
- Disorders
of the gut-brain interactions - 2 hours - Esophageal
motor disorders - 1 hour - Gastro-esophageal
reflux disease and relative complications - 1 hour - Gastroduodenal
Diseases (dyspepsia, acute and chronic gastritis, peptic ulcer and Helicobacter
pylori infection) - 2 hours - Celiac
disease and food intolerances - 2 hours - Inflammatory
bowel diseases and relative complications - 3 hours - Diverticular
Disease . 1 hour - Acute
and chronic liver disease of infectious, metabolic, iatrogenic or autoimmune
etiology - 4 hours - Acute
and chronic pancreatitis - 2 hours - Cholestatic
diseases - 1 hour - Multiple
endocrine syndromes and neuroendocrine tumors of the gastrointestinal tract - 2 hours
Module: GENERAL SURGERY DIGESTIVE SYSTEM
- IBD: surgical aspects
- Peptic ulcer complications
- Bowel perforation
- Esophageal cancer
- Gastric cancer
- Bowel obstruction
- Bile duct stones and obstructive jaundice
- Small bowel cancers
- Liver neoplasm
- Colo-rectal cancer
- Acute abdomen
- GI Bleeding
- Pancreatic neoplasm
- Bowel ischemia and peritonitis
- Appendicitis
- Ano-rectal diseases
Module: ENDOCRINOLOGY
- Diseases of the hypothalamic–pituitary axis – 3 hours
- Dyslipidemias and metabolic syndrome – 1 hour
- Diabetes mellitus: classification, pathogenesis, diagnosis, and clinical presentation – 2 hours
- Diabetes mellitus: acute and chronic complications – 2 hours
- Diabetes mellitus: new pharmacological treatments – 1 hour
- Hirsutism – 1 hour
- Hypo- and hyperthyroidism – 1 hour
- Dietary aspects of endocrine diseases – 1 hour
- Hypo- and hyperparathyroidism – 1 hour
- Hypo- and hyperadrenalism – 1 hour
- Endocrine hypertension – 1 hour
- Hypogonadism and andropause – 1 hour
- Puberty and gynecomastia – 1 hour
- Erectile dysfunction – 1 hour
- Osteoporosis - 1 hour
- Hypoglycemic syndromes – 1 hour
- Obesity and underweight – 1 hour
- Endocrine disruptors – 1 hour
- Transgender health (endocrine aspects of gender incongruence) – 1 hour
Module: GENERAL SURGERY (ENDOCRINOLOGICAL SURGERY
- Surgical Treatment of Benign Thyroid and Parathyroid Diseases
- Hypo/Hyperparathyroidism
- Surgery of Other Endocrine Glands
- Thyroid cancersSurgery of Thyroid and Parathyroid cancersMedullary Thyroid Carcinoma
Module: CLINICAL PATHOLOGY
- Diseases of the hypothalamic–pituitary axis – 3 hours
- Dyslipidemias and metabolic syndrome – 1 hour
- Diabetes mellitus: classification, pathogenesis, diagnosis, and clinical presentation – 2 hours
- Diabetes mellitus: acute and chronic complications – 2 hours
- Diabetes mellitus: new pharmacological treatments – 1 hour
- Hirsutism – 1 hour
- Hypo- and hyperthyroidism – 1 hour
- Dietary aspects of endocrine diseases – 1 hour
- Hypo- and hyperparathyroidism – 1 hour
- Hypo- and hyperadrenalism – 1 hour
- Endocrine hypertension – 1 hour
- Hypogonadism and andropause – 1 hour
- Puberty and gynecomastia – 1 hour
- Erectile dysfunction – 1 hour
- Osteoporosis - 1 hour
- Hypoglycemic syndromes – 1 hour
- Obesity and underweight – 1 hour
- Endocrine disruptors – 1 hour
- Transgender health (endocrine aspects of gender incongruence) – 1 hour
Sustainability goals
- Academic year2025/2026
- Degree program to which the course belongsMedicine and Surgery
- Languageita
- CFU12 CFU, distributed among 5 integrated didactic modules
- Total duration187.5 hours