Dental School

Activity type

Struttura, funzione e metabolismo delle molecole d'interesse biologico

SSD

BIO/10

Year

N/D

Semester

N/D

CFU

2

Hours distribution

20 classroom hours

Lecturers

Activity type

Struttura, funzione e metabolismo delle molecole d'interesse biologico

SSD

BIO/11

Year

N/D

Semester

N/D

CFU

1

Hours distribution

10 classroom hours

Lecturers

Activity type

Struttura, funzione e metabolismo delle molecole d'interesse biologico

SSD

BIO/11

Year

N/D

Semester

N/D

CFU

1

Hours distribution

10 classroom hours

Lecturers

ANNA SCOTTO D'ABUSCO

Activity type

Diagnostica di laboratorio

SSD

BIO/12

Year

N/D

Semester

N/D

CFU

1

Hours distribution

12 classroom hours

Lecturers

ANNA SCOTTO D'ABUSCO

Activity type

Diagnostica di laboratorio

SSD

BIO/12

Year

N/D

Semester

N/D

CFU

1

Hours distribution

12 classroom hours

Lecturers

MARIO FONTANA

Activity type

Struttura, funzione e metabolismo delle molecole d'interesse biologico

SSD

BIO/10

Year

N/D

Semester

N/D

CFU

1

Hours distribution

10 classroom hours

Lecturers

MARIO FONTANA

Upon completion of the course, the student must acquire knowledge relating to the structure and function of the most common molecules of biochemical interest and the biochemical mechanisms of metabolic activities and their regulation.

Upon completion of the course, the student must acquire knowledge relating to the main qualitative and quantitative laboratory methods of relevance in medicine.

Upon completion of the course, the student must acquire knowledge relating to the structure and function of nucleic acids and the biochemical and molecular mechanisms of nucleic acid replication and transcription.

Module: BIOCHEMISTRY IS
N/D
Module: MOLECULAR BIOLOGY IS
N/D
Module: MOLECULAR BIOLOGY IIS
It is expected that the student has acquired a sufficient knowledge of the topics of structural biochemistry, a basic knowledge of the topics of metabolic biochemistry and that he is able to recognize and describe the molecular structure of the main biomolecules.


Module: CLINICAL BIOCEMISTRU AND CLINICAL MOLECULAR BIOLOGY IS
It is expected that the student has acquired a sufficient knowledge of the topics of structural biochemistry, a basic knowledge of the topics of metabolic biochemistry and that he is able to recognize and describe the molecular structure of the main biomolecules.


Module: CLINICAL BIOCHEMISTRU AND CLINICAL MOLECULAR BIOLOGY IIS
N/D
Module: BIOCHEMISTRY IIS
N/D

Module: BIOCHEMISTRY IS
N/D
Module: MOLECULAR BIOLOGY IS
N/D
Module: MOLECULAR BIOLOGY IIS
Knowledge acquired by attending the Course of Medical Chemistry, scheduled during the first year of the Course of Studies in Dental School and attending Biochemistry and Molecular Biology during the I semester of the second year


Module: CLINICAL BIOCEMISTRU AND CLINICAL MOLECULAR BIOLOGY IS
Knowledge acquired by attending the Course of Medical Chemistry, scheduled during the first year of the Course of Studies in Dentistry and Dental Prosthetics


Module: CLINICAL BIOCHEMISTRU AND CLINICAL MOLECULAR BIOLOGY IIS
N/D
Module: BIOCHEMISTRY IIS
N/D

Module: BIOCHEMISTRY IS
N/D
Module: MOLECULAR BIOLOGY IS
N/D
Module: MOLECULAR BIOLOGY IIS
HORMONES: Chemistry, properties and mechanism of action. Receptors. Signal transduction and second messengers. Hormonal regulation of glycaemia. Hormonal regulation of mineral metabolism (calcium and phosphorus).
TOPICS OF HUMAN BIOCHEMISTRY: Blood clotting. Metabolism of xenobiotics and cytochrome P450. Energy and nutritional needs.
BIOCHEMICAL METHODS: Chromatography. Electrophoresis. Spectrometry. Fluorometry. Recombinant DNA techniques.



Module: CLINICAL BIOCEMISTRU AND CLINICAL MOLECULAR BIOLOGY IS
METABOLISM OF LIPIDS: Digestion and absorption. Catabolism of fatty acids. Metabolism of propionylCoA. Formation of ketone bodies and ketone bodies. Biosynthesis of fatty acids, triacylglycerols and phospholipids. Biosynthesis and catabolism of cholesterol. Lipoproteins and lipid transport.
METABOLISM OF PROTEINS: Digestion and absorption. Proteolytic enzymes. Intracellular degradation of proteins: proteasome. Post-translational modifications of proteins. Metabolism of amino acids: transamination, deamination, and decarboxylation reactions. Biogenic amines. Metabolism of phenylalanine, tryptophan and methionine. Urea cycle. Biosynthesis and catabolism of heme: bilirubin.
METABOLISM OF NUCLEOTIDES: Catabolism of purine bases: uric acid.



Module: CLINICAL BIOCHEMISTRU AND CLINICAL MOLECULAR BIOLOGY IIS
INORGANIC COMPONENTS: water, bioelements (bulk and trace elements), biological buffers.
AMINO ACID AND PEPTIDES: Amino acids: classification, acid-base properties. Peptides: peptide bond, oligopeptides and polypeptides, glutathione.
PROTEINS: Protein structure: primary, secondary, tertiary and quaternary structure, protein denaturation. Globular and fibrous proteins. Hemoprotein: haemoglobin and transport of oxygen and carbon dioxide. Myoglobin. Collagen. Blood plasma proteins: electrophoresis analysis. Immunoglobulins. Enzymes: general characteristics, classification, enzyme kinetics, catalytic mechanisms and regulation of enzymatic activity. Inhibitors. Coenzymes. Isoenzymes.
CARBOHYDRATES: Definition and biochemical role. Monosaccharides. Disaccharides: sucrose, maltose, lactose. Polysaccharides: glycogen, starch, cellulose. Mucopolysaccharides. Glycoproteins and proteoglycans.
LIPIDS: Definition and biochemical role. Fatty acids: saturated and unsaturated fatty acids. Arachidonic acids and its derivatives. Triacylglycerols. Phospholipids. Cholesterol and its derivatives (steroids hormones, vitamin D, bile salts). Lipoproteins. Biological membranes.
NUCLEOTIDES AND NUCLEIC ACIDS: Components: pentoses, heterocyclic nitrogenous bases, nucleotides. DNA and RNA: structure and functions of the informational macromolecules. DNA replication. RNA synthesis, processing, and regulation. Gene expression in eukaryotes. RNA processing in eukaryotes. Mechanism of protein synthesis.
VITAMINS: Structure and functions, water-soluble vitamins, fat-soluble vitamins. Nutritional needs. Hypovitaminosis and hypervitaminosis. Free radicals and antioxidants.
BIOENERGETICS: ATP and other high-energy compounds. Respiratory chain and oxidative phosphorylation. Inhibitors and uncoupling agents of cellular respiration. Biological oxidation-reduction reactions.
METABOLISM OF CARBOHYDRATES: Digestion and absorption. Anaerobic and aerobic glycolysis. Oxidation of pyruvate. Krebs citric acid cycle. Glycogenolysis and glycogen synthesis. Gluconeogenesis. Pentose phosphate pathway. Anaplerotic reactions.
METABOLISM OF LIPIDS: Digestion and absorption. Catabolism of fatty acids. Metabolism of propionylCoA. Formation of ketone bodies and ketone bodies. Biosynthesis of fatty acids, triacylglycerols and phospholipids. Biosynthesis and catabolism of cholesterol. Lipoproteins and lipid transport.
METABOLISM OF PROTEINS: Digestion and absorption. Proteolytic enzymes. Intracellular degradation of proteins: proteasome. Post-translational modifications of proteins. Metabolism of amino acids: transamination, deamination, and decarboxylation reactions. Biogenic amines. Metabolism of phenylalanine, tryptophan and methionine. Urea cycle. Biosynthesis and catabolism of heme: bilirubin.
METABOLISM OF NUCLEOTIDES: Catabolism of purine bases: uric acid.
HORMONES: Chemistry, properties and mechanism of action. Receptors. Signal transduction and second messengers. Hormonal regulation of glycaemia. Hormonal regulation of mineral metabolism (calcium and phosphorus).
TOPICS OF HUMAN BIOCHEMISTRY: Blood clotting. Metabolism of xenobiotics and cytochrome P450. Energy and nutritional needs.
BIOCHEMICAL METHODS: Chromatography. Electrophoresis. Spectrometry. Fluorometry. Recombinant DNA techniques.


Module: BIOCHEMISTRY IIS
INORGANIC COMPONENTS: water, bioelements (bulk and trace elements), biological buffers.
AMINO ACID AND PEPTIDES: Amino acids: classification, acid-base properties. Peptides: peptide bond, oligopeptides and polypeptides, glutathione.
PROTEINS: Protein structure: primary, secondary, tertiary and quaternary structure, protein denaturation. Globular and fibrous proteins. Hemoprotein: haemoglobin and transport of oxygen and carbon dioxide. Myoglobin. Collagen. Blood plasma proteins: electrophoresis analysis. Immunoglobulins. Enzymes: general characteristics, classification, enzyme kinetics, catalytic mechanisms and regulation of enzymatic activity. Inhibitors. Coenzymes. Isoenzymes.
CARBOHYDRATES: Definition and biochemical role. Monosaccharides. Disaccharides: sucrose, maltose, lactose. Polysaccharides: glycogen, starch, cellulose. Mucopolysaccharides. Glycoproteins and proteoglycans.
LIPIDS: Definition and biochemical role. Fatty acids: saturated and unsaturated fatty acids. Arachidonic acids and its derivatives. Triacylglycerols. Phospholipids. Cholesterol and its derivatives (steroids hormones, vitamin D, bile salts). Lipoproteins. Biological membranes.
NUCLEOTIDES AND NUCLEIC ACIDS: Components: pentoses, heterocyclic nitrogenous bases, nucleotides. DNA and RNA: structure and functions of the informational macromolecules. DNA replication. RNA synthesis, processing, and regulation. Gene expression in eukaryotes. RNA processing in eukaryotes. Mechanism of protein synthesis.
VITAMINS: Structure and functions, water-soluble vitamins, fat-soluble vitamins. Nutritional needs. Hypovitaminosis and hypervitaminosis. Free radicals and antioxidants.
BIOENERGETICS: ATP and other high-energy compounds. Respiratory chain and oxidative phosphorylation. Inhibitors and uncoupling agents of cellular respiration. Biological oxidation-reduction reactions.
METABOLISM OF CARBOHYDRATES: Digestion and absorption. Anaerobic and aerobic glycolysis. Oxidation of pyruvate. Krebs citric acid cycle. Glycogenolysis and glycogen synthesis. Gluconeogenesis. Pentose phosphate pathway. Anaplerotic reactions.
METABOLISM OF LIPIDS: Digestion and absorption. Catabolism of fatty acids. Metabolism of propionylCoA. Formation of ketone bodies and ketone bodies. Biosynthesis of fatty acids, triacylglycerols and phospholipids. Biosynthesis and catabolism of cholesterol. Lipoproteins and lipid transport.
METABOLISM OF PROTEINS: Digestion and absorption. Proteolytic enzymes. Intracellular degradation of proteins: proteasome. Post-translational modifications of proteins. Metabolism of amino acids: transamination, deamination, and decarboxylation reactions. Biogenic amines. Metabolism of phenylalanine, tryptophan and methionine. Urea cycle. Biosynthesis and catabolism of heme: bilirubin.
METABOLISM OF NUCLEOTIDES: Catabolism of purine bases: uric acid.
HORMONES: Chemistry, properties and mechanism of action. Receptors. Signal transduction and second messengers. Hormonal regulation of glycaemia. Hormonal regulation of mineral metabolism (calcium and phosphorus).
TOPICS OF HUMAN BIOCHEMISTRY: Blood clotting. Metabolism of xenobiotics and cytochrome P450. Energy and nutritional needs.
BIOCHEMICAL METHODS: Chromatography. Electrophoresis. Spectrometry. Fluorometry. Recombinant DNA techniques.

Module: BIOCHEMISTRY IS
N/D
Module: MOLECULAR BIOLOGY IS
N/D
Module: MOLECULAR BIOLOGY IIS
Nelson, Cox I PRINCIPI DI BIOCHIMICA DI LEHNINGER. Zanichelli ISBN 9788808261489
Siliprandi e Tettamanti BIOCHIMICA MEDICA Piccin ISBN 9788829917501
Tymoczko, Berg Stryer PRINICIPI DI BIOCHIMICA. Zanichelli ISBN 9788808062536
Lieberman, Marks MARKS BIOCHIMICA MEDICA. Casa Editrice Ambrosiana ISBN 9788808182173didactic sections are evaluated by each type of test.



Module: CLINICAL BIOCEMISTRU AND CLINICAL MOLECULAR BIOLOGY IS
Nelson, Cox I PRINCIPI DI BIOCHIMICA DI LEHNINGER. Zanichelli ISBN 9788808261489
Siliprandi e Tettamanti BIOCHIMICA MEDICA Piccin ISBN 9788829917501
Tymoczko, Berg Stryer PRINICIPI DI BIOCHIMICA. Zanichelli ISBN 9788808062536
Lieberman, Marks MARKS BIOCHIMICA MEDICA. Casa Editrice Ambrosiana ISBN 9788808182173




Module: CLINICAL BIOCHEMISTRU AND CLINICAL MOLECULAR BIOLOGY IIS
N/D
Module: BIOCHEMISTRY IIS
N/D

Module: BIOCHEMISTRY IS
N/D
Module: MOLECULAR BIOLOGY IS
N/D
Module: MOLECULAR BIOLOGY IIS
N/D
Module: CLINICAL BIOCEMISTRU AND CLINICAL MOLECULAR BIOLOGY IS
N/D
Module: CLINICAL BIOCHEMISTRU AND CLINICAL MOLECULAR BIOLOGY IIS
N/D
Module: BIOCHEMISTRY IIS
N/D

Module: BIOCHEMISTRY IS
N/D
Module: MOLECULAR BIOLOGY IS
N/D
Module: MOLECULAR BIOLOGY IIS
The teacher delivers lectures with traditional methods with audiovisual aids and scheduling of lessons as reported on GOMP Aure/Orari system, published on the website of the Dental School.


Module: CLINICAL BIOCEMISTRU AND CLINICAL MOLECULAR BIOLOGY IS
The teacher delivers lectures with traditional methods with audiovisual aids and scheduling of lessons as reported on GOMP Aure/Orari system, published on the website of the Dental School.


Module: CLINICAL BIOCHEMISTRU AND CLINICAL MOLECULAR BIOLOGY IIS
N/D
Module: BIOCHEMISTRY IIS
N/D

Module: BIOCHEMISTRY IS
N/D
Module: MOLECULAR BIOLOGY IS
N/D
Module: MOLECULAR BIOLOGY IIS
Following paragraph 4.5 of the Regulations of the Dental School, the student is required to attend educational activities, formal, non-formal, vocational. The frequency is checked by the teachers through signature / updated lists provided by the Academic Office, as established by CCLMOPD. The certificate of mandatory attendance to the teaching course is required to the student to be admitted at the final test.


Module: CLINICAL BIOCEMISTRU AND CLINICAL MOLECULAR BIOLOGY IS
Following paragraph 4.5 of the Regulations of the Dental School, the student is required to attend educational activities, formal, non-formal, vocational. The frequency is checked by the teachers through signature / updated lists provided by the Academic Office, as established by CCLMOPD. The certificate of mandatory attendance to the teaching course is required to the student to be admitted at the final test.


Module: CLINICAL BIOCHEMISTRU AND CLINICAL MOLECULAR BIOLOGY IIS
N/D
Module: BIOCHEMISTRY IIS
N/D

Module: BIOCHEMISTRY IS
N/D
Module: MOLECULAR BIOLOGY IS
N/D
Module: MOLECULAR BIOLOGY IIS
To pass the exam it is necessary to achieve a grade of not less than 18/30 in each module. The student must demonstrate that he has acquired a sufficient knowledge of the topics of structural biochemistry, a basic knowledge of the topics of metabolic biochemistry and that he is able to recognize and describe the molecular structure of the main biomolecules.


Module: CLINICAL BIOCEMISTRU AND CLINICAL MOLECULAR BIOLOGY IS
To pass the exam it is necessary to achieve a grade of not less than 18/30 in each module. The student must demonstrate that he has acquired a sufficient knowledge of the topics of structural biochemistry, a basic knowledge of the topics of metabolic biochemistry and that he is able to recognize and describe the molecular structure of the main biomolecules.


Module: CLINICAL BIOCHEMISTRU AND CLINICAL MOLECULAR BIOLOGY IIS
N/D
Module: BIOCHEMISTRY IIS
N/D

Module: BIOCHEMISTRY IS
N/D
Module: MOLECULAR BIOLOGY IS
N/D
Module: MOLECULAR BIOLOGY IIS
The description of one or more topics is requested


Module: CLINICAL BIOCEMISTRU AND CLINICAL MOLECULAR BIOLOGY IS
The description of one or more topics is requested


Module: CLINICAL BIOCHEMISTRU AND CLINICAL MOLECULAR BIOLOGY IIS
N/D
Module: BIOCHEMISTRY IIS
N/D

Module: BIOCHEMISTRY IS
N/D
Module: MOLECULAR BIOLOGY IS
N/D
Module: MOLECULAR BIOLOGY IIS

• HORMONES-4 hours Chemistry, properties and mechanism of action. Receptors. Signal transduction and second messengers. Hormonal regulation of glycaemia. Hormonal regulation of mineral metabolism (calcium and phosphorus).
  • Books: Teaching materials provided by the professor (slides) and reference textbooks indicated during the lectures


• TOPICS OF HUMAN BIOCHEMISTRY- 2 hours: Blood clotting. Metabolism of xenobiotics and cytochrome P450. Energy and nutritional needs.
  • Books: Teaching materials provided by the professor (slides) and reference textbooks indicated during the lectures


• BIOCHEMICAL METHODS- 2hours Chromatography. Electrophoresis. Spectrometry. Fluorometry. Recombinant DNA techniques.
  • Books: Teaching materials provided by the professor (slides) and reference textbooks indicated during the lectures

• METABOLISM OF LIPIDS- 4 hours: Digestion and absorption. Catabolism of fatty acids. Metabolism of propionylCoA. Formation of ketone bodies and ketone bodies. Biosynthesis of fatty acids, triacylglycerols and phospholipids. Biosynthesis and catabolism of cholesterol. Lipoproteins and lipid transport.
  • Books: Teaching materials provided by the professor (slides) and reference textbooks indicated during the lectures


• METABOLISM OF PROTEINS-5 hours: Digestion and absorption. Proteolytic enzymes. Intracellular degradation of proteins: proteasome. Post-translational modifications of proteins. Metabolism of amino acids: transamination, deamination, and decarboxylation reactions. Biogenic amines. Metabolism of phenylalanine, tryptophan and methionine. Urea cycle. Biosynthesis and catabolism of heme: bilirubin.
  • Books: Teaching materials provided by the professor (slides) and reference textbooks indicated during the lectures


• METABOLISM OF NUCLEOTIDES- 3 hours: Catabolism of purine bases: uric acid.
  • Books: Teaching materials provided by the professor (slides) and reference textbooks indicated during the lectures