Nursing - Course J - ASL Roma 1/Ospedale Santo Spirito

Activity type

Scienze propedeutiche

SSD

PHYS-06/A

Year

1st year

Semester

1st semester

CFU

1

Hours distribution

12 classroom hours

Lecturers

Rita Consorti

Activity type

Scienze biomediche

SSD

BIOS-07/A

Year

1st year

Semester

1st semester

CFU

2

Hours distribution

24 classroom hours

Lecturers

FABIO DI DOMENICO

Activity type

Scienze biomediche

SSD

BIOS-10/A

Year

1st year

Semester

1st semester

CFU

2

Hours distribution

24 classroom hours

Lecturers

ALESSANDRO ROSA

Activity type

Scienze biomediche

SSD

MEDS-01/A

Year

1st year

Semester

1st semester

CFU

1

Hours distribution

12 classroom hours

Lecturers

IRENE BOTTILLO

By the end of the course, students will be able to:

* describe the structure and main functions of cells;
* explain the structure and biological role of the major classes of biomolecules;
* understand the fundamental processes of cellular metabolism and energy production;
* describe the main mechanisms of DNA replication, gene expression, and cell communication;
* relate molecular and cellular processes to the functioning of the human body;
* recognize the consequences of major molecular and cellular alterations in pathological conditions;
* use basic biological and biochemical terminology correctly;
* integrate the acquired knowledge with subsequent biomedical and nursing disciplines.

Knowedge of basic chemistry

Module:
N/D
Module:
Amino acids: classification, acid-base properties, amino acid precursors of biogenic amines. Peptides. Peptide bond, oligopeptides and polypeptides.
Protein: structural organization of proteins: primary, secondary, tertiary and quaternary. Globular proteins and fibrous. Hemoglobin and transport oxygen and carbon dioxide.
Carbohydrates: definition and meaning. Monosaccharides: glyceraldehyde, glucose, fructose, ribose and deoxyribose. Disaccharides: maltose, lactose and sucrose. Polysaccharides: glycogen, starch and cellulose.
Lipids: definition and meaning. Saturated and unsaturated fatty acids, triglycerides, phospholipids and steroids (cholesterol). chemical structure of biological membranes.
Enzymes: mechanism of action. Enzyme kinetics. enzymatic regulation. Classification.
Metabolism: general concepts, meaning theAmino ATP, direct and oxidative phosphorylation.


Module:
Introduction to biology and the general properties of living matter

Cellular organization of living matter: structure and functions of the cell
• Prokaryotic cell, eukaryotic cell
• The plasma membrane: structure, function, membrane transport, vesicular transport (exocytosis and endocytosis)
• The cell nucleus, the cytoplasm
• Cellular compartments: smooth and rough endoplasmic reticulum, Golgi apparatus and protein transport, protein targeting and modification
• Biogenesis and function of organelles and cellular structures: ribosomes, mitochondria, lysosomes, peroxisomes, membrane-less organelles (biomolecular condensates)
• The cytoskeleton, cell junctions, the extracellular matrix
• Interaction and communication between cells
• Cell duplication: cell cycle, mitosis, and meiosis

Cellular mechanisms of transmission and control of genetic and epigenetic information
• Nucleic acids: DNA and RNA — composition, structure, functions
• DNA replication, transcription, genetic code, translation
• Gene and genome: gene structure; complexity of eukaryotic genes
• Control and regulation of gene expression (overview)
• Overview of non-coding RNAs and their biological function
• Chromatin and chromosomes



Module:
N/D

Module:
N/D
Module:
Samaja – Paroni: Chimica e biochimica
Michele Samaja : corso di Biochimica per le lauree sanitarie- Piccin
Massimo Stefani, Niccolò Taddei : Chimica, Biochimica e Biologia Applicata – Zanichelli
A.L. Lehninger, D. L. Nelson, M.M. Cox - INTRODUZIONE ALLA BIOCHIMICA (terza edizione) - Zanichelli


Module:
N/D
Module:
N/D

Module:
N/D
Module:
N/D
Module:
N/D
Module:
N/D

In presence lessons

Mandatory frequence

Written test and oral test if needed

Describe the structure of sugars
Describe the structure of lipids
Highlight the levels of protein structure
Describe the structure and function of hemoglobin
Describe the role of enzymes in enzyme catalysis

Module:
N/D
Module:

• Atomic Structure, Chemical Bonds


• Acids and bases


• Carbon Chemistry, Structure of Sugars


• Structure of lipids


• Protein structure


• Hemoglobin and Myoglobin,


• Enzymes


• Bioenergetics, Basic Concepts of Metabolism

• Lessons 1-2: Introduction to biology and the general properties of living matter
  • Books: Biologia. Come funziona la vita. Cellula - Genetica. James R. Morris, Daniel L. Hartl, Andrew H. Knoll, Robert A Lue, Melissa Michael, ZANICHELLI


• Lessons 3-7: Cellular organization of living matter: structure and functions of the cell
  • Books: Biologia. Come funziona la vita. Cellula - Genetica. James R. Morris, Daniel L. Hartl, Andrew H. Knoll, Robert A Lue, Melissa Michael, ZANICHELLI


• Lessons 8-12: Cellular mechanisms of transmission and control of genetic and epigenetic information
  • Books: Biologia. Come funziona la vita. Cellula - Genetica. James R. Morris, Daniel L. Hartl, Andrew H. Knoll, Robert A Lue, Melissa Michael, ZANICHELLI