Catalogo dei Corsi di studio

WORK EXPERIENCE

03/01/2021-Now RTDA
Professor Gian Gaetano Tartaglia s research group
Department of Biology and Biotechnology Charles Darwin
Sapienza University of Rome
Teacher of the Computational Methods in Biology course
Teacher @ Corso di Alta Formazione in Bioinformatica

01/04/2020-31/12/2021
Post-Doc
Professor Gian Gaetano Tartaglia s RNA Systems Biology research group
Center for Life Nano- & Neuro-Science
Istituto Italiano di Tecnologia

01/12/2014-31/03/2020
Post-Doc
Professor Irene Bozzoni s research group.
Department of Biology and Biotechnology Charles Darwin
Sapienza University of Rome

2020/2021 Academic Year
Contract Professor
Genetics and Molecular Biology master degree course
Department of Biology and Biotechnology Charles Darwin
Sapienza University of Rome
Teacher of the Computational Methods in Biology course

EDUCATION AND TRAINING

2011/2015
PhD in Cellular and Molecular Biology (Bioinformatics Curriculum)
Tor Vergata University of Rome

2009/2011
Master Degree in Bioinformatics 110/110 cum Laude
Tor Vergata University of Rome

2006/2009
Bachelor degree in Cellular and Molecular Biology 110/110 cum Laude
Tor Vergata University of Rome

WORK ACTIVITIES:

Editorial activity:
Associate and Review Editor @ Frontiers in Molecular Biosciences

Conferences/Workshops/Practical Courses:
05/2012 University of Catania
Annual meeting of the Bioinformatics Italian Society
Oral Talk entitled "Alternative splicing as regulator of protein-protein interactions".
07/2013 Berlin ISMB/ECCB
Presentiation of a poster entitled "Global characterization of alternative splicing events in long non coding RNAs"
02/2014 La Sapienza University of Rome
Annual meeting of the Bioinformatics Italian Society
Presentiation of a poster entitled "Global characterization of alternative splicing events in long non coding RNAs"
11/2019 EMBL Heidelberg
EMBO Practical Course: "Methods for Analysis of Circular RNAs: No Tautology"
Participation as a trainer in the Data Analysis section
04/2022 EMBL Heidelberg
EMBO Practical Course: "Methods for analysis of circRNAs: From discovery to function"
Participation as a trainer in the Data Analysis section
11/2022 EMBL Heidelberg
EMBO Workshop: "From functional genomics to systems biology"
Presentation of a poster entitled Multi-omics analysis reveals a crucial role for Retinoic Acid in promoting epigenetic and transcriptional competence of an in vitro model of human Pharyngeal Endoderm
05/2023 Collegium Iuridicum Novum, Poznan
EMBO Workshop: Non-coding RNA medicine
Oral presentation entitled FUS Alters circRNA Metabolism in Human Motor Neurons Carrying the ALS-Linked P525L Mutation .

FIELDS OF INTEREST:
Bioinformatics and Computational Biology; Genomics and Transcriptomics; Interaction between RNA and other biomolecules.

PUBLICATIONS (Source: SCOPUS):

Benedetti M.C., D'andrea T., Colantoni A., Silachev D., de Turris V., Boussadia Z., Babenko V.A., Volovikov E.A., Belikova L., Bogomazova A.N., Pepponi R., Whye D., Buttermore E.D., Tartaglia G.G., Lagarkova M.A., Katanaev V.L., Musayev I., Martinelli S., Fucile S., Rosa A.
Cortical neurons obtained from patient-derived iPSCs with GNAO1 p.G203R variant show altered differentiation and functional properties
(2024) Heliyon, 10 (5), art. no. e26656
DOI: 10.1016/j.heliyon.2024.e26656

Centrón-Broco A., Rossi F., Grelloni C., Garraffo R., Dattilo D., Giuliani A., Di Timoteo G., Colantoni A., Bozzoni I., Beltran Nebot M.
CircAFF1 Is a Circular RNA with a Role in Alveolar Rhabdomyosarcoma Cell Migration
(2023) Biomedicines, 11 (7), art. no. 1893
DOI: 10.3390/biomedicines11071893

Colantoni, A., Capauto, D., Alfano, V., D Ambra, E., D Uva, S., Tartaglia, G.G., Morlando, M.
FUS Alters circRNA Metabolism in Human Motor Neurons Carrying the ALS-Linked P525L Mutation
(2023) International Journal of Molecular Sciences, 24 (4), art. no. 3181, .
DOI: 10.3390/ijms24043181

Vandelli, A., Arnal Segura, M., Monti, M., Fiorentino, J., Broglia, L., Colantoni, A., Sanchez de Groot, N., Torrent Burgas, M., Armaos, A., Tartaglia, G.G.
The PRALINE database: protein and Rna humAn singLe nucleotIde variaNts in condEnsates
(2023) Bioinformatics (Oxford, England), 39 (1), .
DOI: 10.1093/bioinformatics/btac847

Fiorillo, C., Yen, P.-S., Colantoni, A., Mariconti, M., Azevedo, N., Lombardo, F., Failloux, A.-B., Arcà, B.
MicroRNAs and other small RNAs in Aedes aegypti saliva and salivary glands following chikungunya virus infection
(2022) Scientific Reports, 12 (1), art. no. 9536, . Cited 1 time.
DOI: 10.1038/s41598-022-13780-3

Chen, L., Roake, C.M., Maccallini, P., Bavasso, F., Dehghannasiri, R., Santonicola, P., Mendoza-Ferreira, N., Scatolini, L., Rizzuti, L., Esposito, A., Gallotta, I., Francia, S., Cacchione, S., Galati, A., Palumbo, V., Kobin, M.A., Tartaglia, G.G., Colantoni, A., Proietti, G., Wu, Y., Hammerschmidt, M., De Pittà, C., Sales, G., Salzman, J., Pellizzoni, L., Wirth, B., Di Schiavi, E., Gatti, M., Artandi, S.E., Raffa, G.D.
TGS1 impacts snRNA 3'-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration
(2022) Nucleic Acids Research, 50 (21), pp. 12400-12424.
DOI: 10.1093/nar/gkac659

Carvelli, A., Setti, A., Desideri, F., Galfrè, S.G., Biscarini, S., Santini, T., Colantoni, A., Peruzzi, G., Marzi, M.J., Capauto, D., Di Angelantonio, S., Ballarino, M., Nicassio, F., Laneve, P., Bozzoni, I.
A multifunctional locus controls motor neuron differentiation through short and long noncoding RNAs
(2022) EMBO Journal, 41 (13), art. no. e108918, . Cited 2 times.
DOI: 10.15252/embj.2021108918

Scalzitti, S., Mariani, D., Setti, A., Colantoni, A., Lisi, M., Bozzoni, I., Martone, J.
Lnc-SMaRT Translational Regulation of Spire1, A New Player in Muscle Differentiation
(2022) Journal of Molecular Biology, 434 (2), art. no. 167384, .
DOI: 10.1016/j.jmb.2021.167384

Rossi, F., Beltran, M., Damizia, M., Grelloni, C., Colantoni, A., Setti, A., Di Timoteo, G., Dattilo, D., Centrón-Broco, A., Nicoletti, C., Fanciulli, M., Lavia, P., Bozzoni, I.
Circular RNA ZNF609/CKAP5 mRNA interaction regulates microtubule dynamics and tumorigenicity
(2022) Molecular Cell, 82 (1), pp. 75-89.e9. Cited 15 times.
DOI: 10.1016/j.molcel.2021.11.032

Armaos, A., Colantoni, A., Proietti, G., Rupert, J., Tartaglia, G.G.
CatRAPID omics v2.0: Going deeper and wider in the prediction of protein-RNA interactions
(2021) Nucleic Acids Research, 49 (1), pp. W72-W79. Cited 21 times.
DOI: 10.1093/nar/gkab393

Rossi, F., Centrón-Broco, A., Dattilo, D., Di Timoteo, G., Guarnacci, M., Colantoni, A., Nebot, M.B., Bozzoni, I.
CircVAMP3: A circRNA with a role in alveolar rhabdomyosarcoma cell cycle progression
(2021) Genes, 12 (7), art. no. 985, . Cited 4 times.
DOI: 10.3390/genes12070985

Dobrowolny, G., Martone, J., Lepore, E., Casola, I., Petrucci, A., Inghilleri, M., Morlando, M., Colantoni, A., Scicchitano, B.M., Calvo, A., Bisogni, G., Chiò, A., Sabatelli, M., Bozzoni, I., Musarò, A.
A longitudinal study defined circulating microRNAs as reliable biomarkers for disease prognosis and progression in ALS human patients
(2021) Cell Death Discovery, 7 (1), art. no. 4, . Cited 20 times.
DOI: 10.1038/s41420-020-00397-6

Cipriano, A., Macino, M., Buonaiuto, G., Santini, T., Biferali, B., Peruzzi, G., Colantoni, A., Mozzetta, C., Ballarino, M.
Epigenetic regulation of wnt7b expression by the cis-acting long noncoding rna lnc-rewind in muscle stem cells
(2021) eLife, 10, art. no. e54782, pp. 1-25. Cited 15 times.
DOI: 10.7554/ELIFE.54782

Desideri, F., Cipriano, A., Petrezselyova, S., Buonaiuto, G., Santini, T., Kasparek, P., Prochazka, J., Janson, G., Paiardini, A., Calicchio, A., Colantoni, A., Sedlacek, R., Bozzoni, I., Ballarino, M.
Intronic Determinants Coordinate Charme lncRNA Nuclear Activity through the Interaction with MATR3 and PTBP1
(2020) Cell Reports, 33 (12), art. no. 108548, . Cited 14 times.
DOI: 10.1016/j.celrep.2020.108548

Garone, M.G., Alfano, V., Salvatori, B., Braccia, C., Peruzzi, G., Colantoni, A., Bozzoni, I., Armirotti, A., Rosa, A.
Proteomics analysis of FUS mutant human motoneurons reveals altered regulation of cytoskeleton and other ALS-linked proteins via 3 UTR binding
(2020) Scientific Reports, 10 (1), art. no. 11827, . Cited 10 times.
DOI: 10.1038/s41598-020-68794-6

Martone, J., Lisi, M., Castagnetti, F., Rosa, A., Di Carlo, V., Blanco, E., Setti, A., Mariani, D., Colantoni, A., Santini, T., Perone, L., Di Croce, L., Bozzoni, I.
Trans-generational epigenetic regulation associated with the amelioration of Duchenne Muscular Dystrophy
(2020) EMBO Molecular Medicine, 12 (8), art. no. e12063, . Cited 7 times.
DOI: 10.15252/emmm.202012063

Colantoni, A., Rupert, J., Vandelli, A., Tartaglia, G.G., Zacco, E.
Zooming in on protein RNA interactions: a multilevel workflow to identify interaction partners
(2020) Biochemical Society Transactions, 48 (4), pp. 1529-1543. Cited 6 times.
DOI: 10.1042/BST20191059

Martone, J., Mariani, D., Santini, T., Setti, A., Shamloo, S., Colantoni, A., Capparelli, F., Paiardini, A., Dimartino, D., Morlando, M., Bozzoni, I.
SMaRT lncRNA controls translation of a G-quadruplex-containing mRNA antagonizing the DHX36 helicase
(2020) EMBO Reports, 21 (6), art. no. e49942, . Cited 16 times.
DOI: 10.15252/embr.201949942

Di Timoteo, G., Dattilo, D., Centrón-Broco, A., Colantoni, A., Guarnacci, M., Rossi, F., Incarnato, D., Oliviero, S., Fatica, A., Morlando, M., Bozzoni, I.
Modulation of circRNA Metabolism by m6A Modification
(2020) Cell Reports, 31 (6), art. no. 107641, . Cited 135 times.
DOI: 10.1016/j.celrep.2020.107641

Arcà, B., Colantoni, A., Fiorillo, C., Severini, F., Benes, V., Di Luca, M., Calogero, R.A., Lombardo, F.
MicroRNAs from saliva of anopheline mosquitoes mimic human endogenous miRNAs and may contribute to vector-host-pathogen interactions
(2019) Scientific Reports, 9 (1), art. no. 2955, . Cited 17 times.
DOI: 10.1038/s41598-019-39880-1

De Santis, R., Alfano, V., de Turris, V., Colantoni, A., Santini, L., Garone, M.G., Antonacci, G., Peruzzi, G., Sudria-Lopez, E., Wyler, E., Anink, J.J., Aronica, E., Landthaler, M., Pasterkamp, R.J., Bozzoni, I., Rosa, A.
Mutant FUS and ELAVL4 (HuD) Aberrant Crosstalk in Amyotrophic Lateral Sclerosis
(2019) Cell Reports, 27 (13), pp. 3818-3831.e5. Cited 33 times.
DOI: 10.1016/j.celrep.2019.05.085

Rossi, F., Legnini, I., Megiorni, F., Colantoni, A., Santini, T., Morlando, M., Di Timoteo, G., Dattilo, D., Dominici, C., Bozzoni, I.
Circ-ZNF609 regulates G1-S progression in rhabdomyosarcoma
(2019) Oncogene, 38 (20), pp. 3843-3854. Cited 66 times.
DOI: 10.1038/s41388-019-0699-4

Capauto, D., Colantoni, A., Lu, L., Santini, T., Peruzzi, G., Biscarini, S., Morlando, M., Shneider, N.A., Caffarelli, E., Laneve, P., Bozzoni, I.
A Regulatory Circuitry Between Gria2, miR-409, and miR-495 Is Affected by ALS FUS Mutation in ESC-Derived Motor Neurons
(2018) Molecular Neurobiology, 55 (10), pp. 7635-7651. Cited 24 times.
DOI: 10.1007/s12035-018-0884-4

Ballarino, M., Cipriano, A., Tita, R., Santini, T., Desideri, F., Morlando, M., Colantoni, A., Carrieri, C., Nicoletti, C., Musarò, A., Carroll, D.O., Bozzoni, I.
Deficiency in the nuclear long noncoding RNA Charme causes myogenic defects and heart remodeling in mice
(2018) EMBO Journal, 37 (18), art. no. e99697, . Cited 51 times.
DOI: 10.15252/embj.201899697

Dimartino, D., Colantoni, A., Ballarino, M., Martone, J., Mariani, D., Danner, J., Bruckmann, A., Meister, G., Morlando, M., Bozzoni, I.
The Long Non-coding RNA lnc-31 Interacts with Rock1 mRNA and Mediates Its YB-1-Dependent Translation
(2018) Cell Reports, 23 (3), pp. 733-740. Cited 41 times.
DOI: 10.1016/j.celrep.2018.03.101

Biscarini, S., Capauto, D., Peruzzi, G., Lu, L., Colantoni, A., Santini, T., Shneider, N.A., Caffarelli, E., Laneve, P., Bozzoni, I.
Characterization of the lncRNA transcriptome in mESC-derived motor neurons: Implications for FUS-ALS
(2018) Stem Cell Research, 27, pp. 172-179. Cited 22 times.
DOI: 10.1016/j.scr.2018.01.037

De Santis, R., Santini, L., Colantoni, A., Peruzzi, G., de Turris, V., Alfano, V., Bozzoni, I., Rosa, A.
FUS Mutant Human Motoneurons Display Altered Transcriptome and microRNA Pathways with Implications for ALS Pathogenesis
(2017) Stem Cell Reports, 9 (5), pp. 1450-1462. Cited 58 times.
DOI: 10.1016/j.stemcr.2017.09.004

Errichelli, L., Dini Modigliani, S., Laneve, P., Colantoni, A., Legnini, I., Capauto, D., Rosa, A., De Santis, R., Scarfò, R., Peruzzi, G., Lu, L., Caffarelli, E., Shneider, N.A., Morlando, M., Bozzoni, I.
FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons
(2017) Nature Communications, 8, art. no. 14741, . Cited 297 times.
DOI: 10.1038/ncomms14741

Ferrè, F., Colantoni, A., Helmer-Citterich, M.
Revealing protein-lncRNA interaction
(2016) Briefings in Bioinformatics, 17 (1), pp. 106-116. Cited 391 times.
DOI: 10.1093/bib/bbv031

Colantoni, A., Bianchi, V., Gherardini, P.F., Scalia Tomba, G., Ausiello, G., Helmer-Citterich, M., Ferrè, F.
Alternative splicing tends to avoid partial removals of protein-protein interaction sites
(2013) BMC Genomics, 14 (1), art. no. 379, . Cited 3 times.
DOI: 10.1186/1471-2164-14-379

Bianchi, V., Colantoni, A., Calderone, A., Ausiello, G., Ferrè, F., Helmer-Citterich, M.
DBATE: Database of alternative transcripts expression
(2013) Database, 2013, art. no. bat050, . Cited 11 times.
DOI: 10.1093/database/bat050