METODOLOGIE DIAGNOSTICHE DI ANATOMIA PATOLOGICA Canale unico

Docente coordinatore e verbalizzante: MANILA ANTONELLI

Modulo 1: ISTITUZIONI DI ANATOMIA PATOLOGICA

Tipologia
Scienze e tecniche di laboratorio biomedico
SSD
MED/08
Anno
2º anno
Semestre
1º semestre
CFU
2
Distribuzione delle ore
20 classroom hours
Docenti
FRANCESCA GIANNO

Modulo 2: CITOPATOLOGIA

Tipologia
Scienze e tecniche di laboratorio biomedico
SSD
MED/08
Anno
2º anno
Semestre
1º semestre
CFU
1
Distribuzione delle ore
10 classroom hours
Docenti
MANILA ANTONELLI

Modulo 3: TECNICHE DI MEDICINA DI LABORATORIO

Tipologia
Scienze e tecniche di laboratorio biomedico
SSD
MED/46
Anno
2º anno
Semestre
1º semestre
CFU
1
Distribuzione delle ore
10 classroom hours
Docenti
ANTONIO FRANCESCO CAMPESE

Modulo 4: TECNICHE DI ANATOMIA PATOLOGICA

Tipologia
Scienze e tecniche di laboratorio biomedico
SSD
MED/08
Anno
2º anno
Semestre
1º semestre
CFU
1
Distribuzione delle ore
10 classroom hours
Docenti
MANILA ANTONELLI

Modulo 5: TECNICHE ULTRASTRUTTURALI

Tipologia
Scienze e tecniche di laboratorio biomedico
SSD
MED/46
Anno
2º anno
Semestre
1º semestre
CFU
1
Distribuzione delle ore
10 classroom hours
Docenti
antonietta arcella

Obiettivi formativi

Lo studente acquisisce conosce relative a: 1) problematiche di diagnostica
isto-citopatologica utili ad una corretta scelta ed applicazione
delle metodologie di preparazione dei campioni biologici; 2) rilevanza
diagnostica della corretta applicazione dei protocolli base; 3)quadri
essenziali di patologia ultrastrutturale utili ad una corretta scelta di applicazione
delle metodologie di preparazione dei campioni biologici
in patologia diagnostica; 4) i protocolli base utilizzati in diagnostica
per l’allestimento dei preparati ultrastrutturali; 5)corretta applicazione
delle tecniche speciali alle specifiche problematiche di istopatologia
strutturale e ultrastrutturale. Lo studente deve sape valutare i risultati
ottenuti in termini di qualità e significatività dei preparati, saper costruire,
in singoli casi paradigmatici, il corretto iter di preparazione dei
campioni scegliendo le metodiche più utili alla risoluzione del quesito
istopatologico, conoscere le tecniche d’esame da cadavere utili ad una
corretta collaborazione con il patologo nell’effettuazione del riscontro
autopico.

Risultati di apprendimento attesi

Lo studente dovrà acquisire le conoscenze di base del flusso di lavoro in un laboratorio di anatomia patologica e di alcuni tipi di metodologie di lavorazione applicata alla diagnostica.

Prerequisiti

Nozioni di istologia

Programma dell’insegnamento

Modulo: ISTITUZIONI DI ANATOMIA PATOLOGICA
N/D
Modulo: CITOPATOLOGIA
N/D
Modulo: TECNICHE DI MEDICINA DI LABORATORIO
N/D
Modulo: TECNICHE DI ANATOMIA PATOLOGICA
- Il flusso di lavoro nel laboratorio di diagnostica molecolare.
- Fase preanalitica e fase analitica
- Caratterizzazione molecolare dei tumori solidi: GIST, carcinoma della mammella, carcinoma del colon, carcinoma del polmone, immuno-oncologia
- FISH e campi di applicazioni nei tumori della mammella e del sistema nervoso centrale
- Biopsia liquida



Modulo: TECNICHE ULTRASTRUTTURALI
N/D

Testi di riferimento

Modulo: ISTITUZIONI DI ANATOMIA PATOLOGICA
N/D
Modulo: CITOPATOLOGIA
N/D
Modulo: TECNICHE DI MEDICINA DI LABORATORIO
L . Ruco- A. Scarpa
Anatomia Patologica
Le basi
UTET



Modulo: TECNICHE DI ANATOMIA PATOLOGICA
L . Ruco- A. Scarpa
Anatomia Patologica
Le basi
UTET



Modulo: TECNICHE ULTRASTRUTTURALI
N/D

Bibliografia

Modulo: ISTITUZIONI DI ANATOMIA PATOLOGICA
N/D
Modulo: CITOPATOLOGIA
N/D
Modulo: TECNICHE DI MEDICINA DI LABORATORIO
L . Ruco- A. Scarpa
Anatomia Patologica
Le basi
UTET



Modulo: TECNICHE DI ANATOMIA PATOLOGICA
L . Ruco- A. Scarpa
Anatomia Patologica
Le basi
UTET



Modulo: TECNICHE ULTRASTRUTTURALI
N/D

Modalità di svolgimento

Esame orale

Frequenza

Modulo: ISTITUZIONI DI ANATOMIA PATOLOGICA
N/D
Modulo: CITOPATOLOGIA
N/D
Modulo: TECNICHE DI MEDICINA DI LABORATORIO
N/D
Modulo: TECNICHE DI ANATOMIA PATOLOGICA
N/D
Modulo: TECNICHE ULTRASTRUTTURALI
N/D

Modalità di esame

Prova orale

Esempi di domande

L'indagine immunoistochimica applicata ai tumori

Programmazione delle attività didattiche

Modulo: ISTITUZIONI DI ANATOMIA PATOLOGICA

  • Definizione anatomia patologica, materiali da sottoporre a esame bioptico e metodiche di base - 2 ore
    • Testi di riferimento: Slides

  • INFIAMMAZIONE - 2 ore

  • DISTURBI DELLA PROLIFERAZIONE E DEL DIFFERENZIAMENTO CELLULARE - 2 ore

  • NEOPLASIE e CLASSIFICAZIONE TNM2 - 1 ora  

  • PATOLOGIA CARDIOVASCOLARE - 2 ore

  • PATOLOGIA TIROIDEA - 2 ore

  • PATOLOGIA POLMONARE - 2 ore 

  • PATOLOGIA DELLA MAMMELLA - 2 ore

  • PATOLOGIA GASTRO-INTESTINALE - 2 ore

  • PATOLOGIA CUTANEA. - 1 ora

  •  PATOLOGIA GINECOLOGICA  - 2 ore



Modulo: CITOPATOLOGIA
N/D
Modulo: TECNICHE DI MEDICINA DI LABORATORIO
  • La citofluorimetria: Principi di base

  • La citofluorimetria: applicazioni in anatomia patologica

  • Metodiche per la generazione di modelli murini di patologie umane ‘convenzionali' come 'strumenti' diagnostici: topi transgenici

  • Metodiche per la generazione di modelli murini di patologie umane ‘convenzionali' come 'strumenti' diagnostici: topi knock-out, mantenimento colonie

  • Etica e legislazione della sperimentazione animale: il principio delle 3R



Modulo: TECNICHE DI ANATOMIA PATOLOGICA

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    -       Fase preanalitica e fase analitica


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    -       Caratterizzazione molecolare dei tumori solidi: GIST, carcinoma della mammella,  carcinoma del colon, carcinoma del polmone, immuno-oncologia


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    -       FISH e campi di applicazioni nei tumori della mammella e del sistema nervoso centrale


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    -->
    -       Biopsia liquida



Modulo: TECNICHE ULTRASTRUTTURALI
N/D

Obiettivi per lo sviluppo sostenibile - Agenda ONU 2030

  • Goal4
  • Anno accademico2026/2027
  • Corso di studio a cui afferisce l’insegnamentoTecniche di laboratorio biomedico (abilitante alla professione sanitaria di Tecnico di laboratorio biomedico) - Corso di laurea E - Regione Molise – IRCCS Neuromed Pozzilli
  • Linguaita
  • CFU6 CFU distribuiti in 5 moduli didattici integrati
  • Durata complessiva60 ore