Catalogo dei Corsi di studio

Giampiero Ferraguti
Dipartimento di Medicina Sperimentale, Sapienza Università di Roma
V.le Regina Elena, 324 - 00161 Roma, Italia.
Ufficio: +390649973882
Fax: +390649970458
giampiero.ferraguti@uniroma1.it; G.Ferraguti@policlinicoumberto1.it

Dirigente Medico I livello presso la UOS Laboratorio Centrale SSDC02S1(UOC Patologia Clinica SSDC02).
AOU Policlinico Umberto I
Ricercatore confermato in Biochimica Clinica e Biologia Molecolare Clinica S.S.D. BIO12, Facoltà di Medicina e Odontoiatria - Sapienza Università di Roma.
Professore aggregato di Biochimica Clinica e Biologia Molecolare Clinica.

Insegnamenti:
1) Corso di Laurea Magistrale in Medicina e Chirurgia C
- Medicina di Laboratorio I
- Medicina di Laboratorio II
2) Corso di Laurea Magistrale in Medicina e Chirurgia D
- Medicina di Laboratorio I
- Medicina di Laboratorio II
3) Corso di Laurea Magistrale in Medicina e Chirurgia E
- Medicina di Laboratorio I
4) Scuola di Specializzazione in Microbiologia
- Biochimica Clinica e Biologia Molecolare Clinica
5) Scuola di Specializzazione in Patologia Clinica e Biochimica Clinica
- Biochimica Clinica e Biologia Molecolare Clinica
6) Scuola di Specializzazione in Geriatria
- Biochimica Clinica e Biologia Molecolare Clinica

Istruzione e formazione:
Dottore in Ricerca in Fisiopatologia Chirurgica e gastroenterologia
Sapienza Università di Roma, Italia.
Specialista in Patologia Clinica
Sapienza Università di Roma, Italia.
Laurea in Medicina e Chirurgia
Sapienza Università di Roma, Italia.

Finanziamenti:
Sapienza Università di Roma. Bando per le Medie Attrezzature e per le Grandi Attrezzature di Ateneo 2019
Medie Attrezzature Scientifiche - Medie Attrezzature classe 3
Meccanismi molecolari della regolazione trascrizionale del trasportatore della serotonina e loro impatto sulla dipendenza da alcol.
Importo finanziato 75.000

Pubblicazioni su riviste internazionali:
1. D'Angelo A, Ferraguti G, Petrella C, Greco A, Ralli M, Vitali M, Framarino Dei Malatesta M, Fiore M, Ceccanti M, Messina MP.(2021) Challenges for Midwives' Healthcare Practice in the Next Decade: COVID-19 - Global Climate Changes - Aging and Pregnancy - Gestational Alcohol Abuse. Clin Ter. Jan-Feb;171(1):e30-e36. doi: 10.7417/CT.2021.2277.
2. Ceci FM, Ferraguti G, Petrella C, Greco A, Ralli M, Iannitelli A, Carito V, Tirassa P, Chaldakov GN, Messina MP, Ceccanti M, Fiore M. (2021) Nerve Growth Factor in Alcohol Use Disorders. Curr Neuropharmacol.19(1):45-60. doi: 10.2174/1570159X18666200429003239. PMID: 32348226
3. Martellucci S, Ralli M, Attanasio G, Russo FY, Marcelli V, Greco A, Gallo A, Fiore M, Petrella C, Ferraguti G, Ceccanti M, de Vincentiis M. (2021) Alcohol binge-drinking damage on the vestibulo-oculomotor reflex. Eur Arch Otorhinolaryngol. Jan;278(1):41-48. doi: 10.1007/s00405-020-06052-1. Epub 2020 May 24. PMID: 32449024
4. Petrella C, Ferraguti G, Tarani L, Chaldakov G N, Ceccanti M, Greco A, Ralli M, Fiore M. (2021) Olive polyphenols and chronic alcohol protection. Olives and Olive Oil in Health and Disease Prevention. DOI: https://doi.org/10.1016/B978-0-12-819528-4.00003-1 Chapter 39 - © 2021 Elsevier Inc. All rights reserved.
5. Ferraguti G, Codazzo C, Petrella C, Coccurello R, Ceccanti M, Fiore M. (2020) Brainstem expression of SLC6A4, HTR2C, NGF, BDNF, TRKA NGF, TRKB BDNF and P75 NTR following paternal alcohol exposure in the male mouse. Biomedical Reviews 2020; 31: 75-89
6. D'Angelo A, Ceccanti M, Fiore M, Petrella C, Greco A, Porrari R, Gencarelli S, Ralli M, Vitali M, Ferraguti G, Galeoto G, Valente D, Framarino Dei Malatesta M, Messina MP. (2020) Pregnancy in women with physical and intellectual disability: psychiatric implications. Riv Psichiatr. Nov-Dec;55(6):331-336. doi: 10.1708/3503.34890. PMID: 33349725
7. Ciafrè S, Ferraguti G, Greco A, Polimeni A, Ralli M, Ceci FM, Ceccanti M, Fiore M. (2020) Alcohol as an early life stressor: Epigenetics, metabolic, neuroendocrine and neurobehavioral implications. Neurosci Biobehav Rev. Nov;118:654-668. doi: 10.1016/j.neubiorev.2020.08.018. Epub 2020 Sep 22. PMID: 32976915
8. Ceci FM, Ferraguti G, Petrella C, Greco A, Tirassa P, Iannitelli A, Ralli M, Vitali M, Ceccanti M, Chaldakov GN, Versacci P, Fiore M. (2020) Nerve Growth Factor, Stress and Diseases. Curr Med Chem. Aug 18. doi: 10.2174/0929867327999200818111654. Online ahead of print. PMID: 32811396
9. Anastasi E, Ialongo C, Labriola R, Ferraguti G, Lucarelli M, Angeloni A. (2020) Vitamin K deficiency and covid-19. Scand J Clin Lab Invest. Nov;80(7):525-527. doi: 10.1080/00365513.2020.1805122. Epub 2020 Aug 11. PMID: 32779537
10. Tarani L, Carito V, Ferraguti G, Petrella C, Greco A, Ralli M, Messina MP, Rasio D, De Luca E, Putotto C, Versacci P, Ceccanti M, Fiore M. (2020) Neuroinflammatory Markers in the Serum of Prepubertal Children with Down Syndrome. J Immunol Res. Mar 23;2020:6937154. doi: 10.1155/2020/6937154. eCollection 2020. PMID: 32280719
11. Petrella C, Carito V, Carere C, Ferraguti G, Ciafrè S, Natella F, Bello C, Greco A, Ralli M, Mancinelli R, Messina MP, Fiore M, Ceccanti M. (2020) Oxidative stress inhibition by resveratrol in alcohol-dependent mice. Nutrition. Nov-Dec;79-80:110783. doi: 10.1016/j.nut.2020.110783. Epub 2020 Mar 2. PMID: 32569950
12. Messina MP, D'Angelo A, Battagliese G, Coriale G, Tarani L, Pichini S, Rasio D, Parlapiano G, Fiore M, Petrella C, Vitali M, Ferraguti G, Ceccanti M; FASD Study Group. (2020) Fetal alcohol spectrum disorders awareness in health professionals: implications for psychiatry. Riv Psichiatr. Mar-Apr;55(2):79-89. doi: 10.1708/3333.33022. PMID: 32202545
13. Coriale G, Gencarelli S, Battagliese G, Delfino D, Fiorentino D, Petrella C, Greco A, Ralli M, Attilia ML, Messina MP, Ferraguti G, Fiore M, Ceccanti M, Messina MP. (2020) Physiological Responses to Induced Stress in Individuals Affected by Alcohol Use Disorder with Dual Diagnosis and Alexithymia. Clin Ter. Mar-Apr;171(2):e120-e129. doi: 10.7417/CT.2020.2201. PMID: 32141483
14. D'Angelo A, Ceccanti M, Petrella C, Greco A, Tirassa P, Rosso P, Ralli M, Ferraguti G, Fiore M, Messina MP. (2020) Role of neurotrophins in pregnancy, delivery and postpartum. Eur J Obstet Gynecol Reprod Biol. Apr; 247:32-41. doi: 10.1016/j.ejogrb.2020.01.046. Epub 2020 Jan 30. PMID: 32058187
15. Ciafrè S, Ferraguti G, Tirassa P, Iannitelli A, Ralli M, Greco A, Chaldakov GN, Rosso P, Fico E, Messina MP, Carito V, Tarani L, Ceccanti M, Fiore M. (2020) Nerve growth factor in the psychiatric brain. Riv Psichiatr. Jan-Feb;55(1):4-15. doi: 10.1708/3301.32713. PMID: 32051620
16. Lucarelli M, Ferraguti G, Fuso A. (2019) Active Demethylation of Non-CpG Moieties in Animals: A Neglected Research Area. Int J Mol Sci. Dec 12;20(24):6272. doi: 10.3390/ijms20246272. PMID: 31842376
17. Ferraguti G, Merlino L, Battagliese G, Piccioni MG, Barbaro G, Carito V, Messina MP, Scalese B, Coriale G, Fiore M, Ceccanti M. (2020) Fetus morphology changes by second-trimester ultrasound in pregnant women drinking alcohol. Addict Biol. May;25(3):e12724. doi: 10.1111/adb.12724. Epub 2019 Feb 27. PMID: 30811093
18. Carito V, Ceccanti M, Ferraguti G, Coccurello R, Ciafrè S, Tirassa P, Fiore M. (2019) NGF and BDNF Alterations by Prenatal Alcohol Exposure Curr Neuropharmacol. 17(4):308-317. doi: 10.2174/1570159X15666170825101308. PMID: 28847297
19. Ciafre' S, Carito V, Ferraguti G, Greco A, Chaldakov GN, Fiore M, Ceccanti M. (2019) How Alcohol Drinking Affects our Genes: An Epigenetic Point of View. Biochem Cell Biol. Aug;97(4):345-356. doi: 10.1139/bcb-2018-0248. Epub 2018 Nov 9. PMID: 30412425
20. Carito V, Parlapiano G, Rasio D, Paparella R, Paolucci V, Ferraguti G, Greco A, Ralli M, Pichini S, Fiore M, Coriale G, Ceccanti M, Tarani L. (2018) Fetal alcohol spectrum disorders in pediatrics FASD and the pediatrician. Biomed Rev; 29: 27-35.
21. Ciafrè S, Carito V, Ferraguti G, Greco A, Ralli M, Tirassa P, Chaldakov GN, Messina MP, Attilia ML, Ciccarelli R, Tarani L, Ceccanti M, Fiore M. (2018) Nerve growth factor in brain diseases. Biomed Rev; 29: 1-16.
22. Vitali M, Mistretta M, Alessandrini G, Coriale G, Romeo M, Attilia F, Rotondo C, Sorbo F, Pisciotta F, Attilia ML, Ceccanti M. (2018) Interdisciplinary Study Group CRARL - SITAC - SIPaD - SITD - SIPDip. Pharmacological treatment for dual diagnosis: a literature update and a proposal of intervention. Riv Psichiatr. May-Jun;53(3):160-169. doi: 10.1708/2925.29419. PMID: 29912219
23. Vitali M, Sorbo F, Mistretta M, Scalese B, Porrari R, Galli D, Coriale G, Rotondo C, Solombrino S, Attilia ML. (2018) Interdisciplinary Study Group CRARL - SITAC - SIPaD - SITD - SIPDip. Dual diagnosis: an intriguing and actual nosographic issue too long neglected. Riv Psichiatr. May-Jun;53(3):154-159. doi: 10.1708/2925.29418. PMID: 29912218
24. Vitali M, Sorbo F, Mistretta M, Coriale G, Messina MP, Alessandrini G, Attilia F, Rotondo C, Gencarelli S, Ledda R, Galli D, Ceccanti M. (2018) Interdisciplinary Study Group CRARL - SITAC - SIPaD - SITD - SIPDip. Drafting a dual diagnosis program: a tailored intervention for patients with complex clinical needs. Riv Psichiatr. May-Jun;53(3):149-153. doi: 10.1708/2925.29417. PMID: 29912217
25. Coriale G, Fiorentino D, De Rosa F, Solombrino S, Scalese B, Ciccarelli R, Attilia F, Vitali M, Musetti A, Fiore M, Ceccanti M. (2018) Interdisciplinary Study Group CRARL - SITAC - SIPaD - SITD - SIPDip. Treatment of alcohol use disorder from a psychological point of view. Riv Psichiatr. May-Jun;53(3):141-148. doi: 10.1708/2925.29416. PMID: 29912216
26. Coriale G, Fiorentino D, Porrari R, Battagliese G, Capriglione I, Cereatti F, Iannuzzi S, Mauri B, Galli D, Fiore M, Attilia ML, Ceccanti M. (2018) Interdisciplinary Study Group CRARL - SITAC - SIPaD - SITD - SIPDip. Diagnosis of alcohol use disorder from a psychological point of view. Riv Psichiatr. May-Jun;53(3):128-140. doi: 10.1708/2925.29415. PMID: 29912215
27. Attilia F, Perciballi R, Rotondo C, Capriglione I, Iannuzzi S, Attilia ML, Vitali M, Alessandrini G, Scamporrino MCM, Fiore M, Ceccanti M. (2018) Interdisciplinary Study Group CRARL - SITAC - SIPaD - SITD - SIPDip. Pharmacological treatment of alcohol use disorder. Scientific evidence. Riv Psichiatr. May-Jun;53(3):123-127. doi: 10.1708/2925.29414. PMID: 29912214
28. Attilia F, Perciballi R, Rotondo C, Capriglione I, Iannuzzi S, Attilia ML, Coriale G, Vitali M, Cereatti F, Fiore M, Ceccanti M. (2018) Interdisciplinary Study Group CRARL - SITAC - SIPaD - SITD - SIPDip. Alcohol withdrawal syndrome: diagnostic and therapeutic methods. Riv Psichiatr. May-Jun;53(3):118-122. doi: 10.1708/2925.29413. PMID: 29912213
29. Alessandrini G, Ciccarelli R, Battagliese G, Lombardo G, De Rosa F, Messina MP, Vitali M, Pisciotta F, Nanut M, Attilia ML, Ceccanti M. (2018) Interdisciplinary Study Group CRARL - SITAC - SIPaD - SITD - SIPDip. Treatment of alcohol dependence. Alcohol and the young: social point of view. Riv Psichiatr. May-Jun;53(3):113-117. doi: 10.1708/2925.29412. PMID: 29912212
30. Alessandrini G, Ciccarelli R, Battagliese G, Cereatti F, Gencarelli S, Messina MP, Vitali M, De Rosa F, Ledda R, Mancini S, Attilia ML. Interdisciplinary Study Group CRARL - SITAC - SIPaD - SITD - SIPDip. (2018) Treatment of alcohol dependence. Alcohol and homelessness: social point of view Riv Psichiatr. May-Jun;53(3):107-112. doi: 10.1708/2925.29411. PMID: 29912211
31. Ciafrè S, Carito V, Tirassa P, Ferraguti G, Attilia ML, Ciolli P, Messina MP, Ceccanti M, Fiore M. (2017) Ethanol Consumption and Innate Neuroimmunity. Biomedical Reviews. 28: 53-65
32. Ferraguti, G; Ciolli, P; Carito, V; Battagliese, G; Mancinelli, R; Ciafrè, S; Tirassa, P; Ciccarelli, R; Cipriani, A; Messina, M P; Fiore, M; Ceccanti, M. (2017). Ethylglucuronide in the urine as a marker of alcohol consumption during pregnancy: Comparison with four alcohol screening questionnaires. Toxicology Letters, Elsevier Science Ireland Limited, 2017, Vol. 275, p. 49-56, ISSN: 0378-4274, ISBN: 0378-4274, doi: 10.1016/j.toxlet.2017.04.016. PMID: 28455000
33. Pascale E., di Battista M. E., Rubino A., Purcaro C., Valente M., Fattapposta F., Ferraguti G., Meco G. (2016). Genetic architecture of MAPT gene region in parkinson disease subtypes. FRONTIERS IN CELLULAR NEUROSCIENCE, vol. 10, ISSN: 1662-5102, doi: 10.3389/fncel.2016.00096 PMID: 27147968
34. Fiore M., Ceccanti M., Carito V., Tarani L., Ferraguti G., Chaldakov G. N. (2016). Neurotrophins' Modulation by Olive Polyphenols. CURRENT MEDICINAL CHEMISTRY, ISSN: 1875-533X PMID: 27356540
35. Ceccanti M., Coccurello R., Carito V., Ciafrè S., Ferraguti G., Giacovazzo G., Mancinelli R., Tirassa P., Chaldakov G. N., Pascale E., Ceccanti M., Codazzo C., Fiore M. (2016). Paternal alcohol exposure in mice alters brain NGF and BDNF and increases ethanol-elicited preference in male offspring. ADDICTION BIOLOGY, vol. 1, p. 776-787, ISSN: 1355-6215, doi: 10.1111/adb.12255 PMID: 25940002
36. Lucarelli M., Bruno S. M., Pierandrei S., Ferraguti G., Testino G., Truglio G., Strom R., Quattrucci S. (2016). The Impact on Genetic Testing of Mutational Patterns of CFTR Gene in Different Clinical Macrocategories of Cystic Fibrosis. JOURNAL OF MOLECULAR DIAGNOSTICS, vol. 18, p. 554-565, ISSN: 1525-1578, doi: 10.1016/j.jmoldx.2016.02.007 PMID: 27157324
37. Lucarelli M., Bruno S. M., Pierandrei S., Ferraguti G., Stamato A., Narzi F., Amato A., Cimino G., Bertasi S., Quattrucci S., Strom R. (2015). A Genotypic-oriented View of CFTR Genetics Highlights Specific Mutational Patterns Underlying Clinical Macro-categories of Cystic Fibrosis. MOLECULAR MEDICINE, vol. 21, p. 257-275, ISSN: 1076-1551, doi: 10.2119/molmed.2014.00229 PMID: 25910067
38. Ferraguti G., Pascale E., Codazzo C., Passarelli F., Mancinelli R., Bonvicini C., Bruno S.M., Lucarelli M., Ceccanti M. (2015). Alcohol Dependence and Serotonin Transporter Functional Polymorphisms 5-HTTLPR and rs25531 in an Italian Population. ALCOHOL AND ALCOHOLISM, vol. 50, p. 259-265, ISSN: 0735-0414, doi: 10.1093/alcalc/agv014 PMID: 25770138
39. Ferraguti G., Pascale E., Lucarelli M. (2015). Alcohol addiction: a molecular biology perspective. CURRENT MEDICINAL CHEMISTRY, vol. 22, p. 670-684, ISSN: 0929-8673, doi: 10.2174/0929867321666141229103158 PMID: 25544474
40. Montali A., Truglio G., Martino F., Ceci F., Ferraguti G., Ciociola E., Maranghi M., Gianfagna F., Iacoviello L., Strom R., Lucarelli M., Arca M. (2015). Atherogenic dyslipidemia in children: evaluation of clinical, biochemical and genetic aspects. PLOS ONE, vol. 10, p. 10(4):e0120099, ISSN: 1932-6203, doi: 10.1371/journal.pone.0120099 PMID: 25897955
41. Fuso A., Ferraguti G., Scarpa S., Ferrer I., Lucarelli M. (2015). Disclosing bias in bisulfite assay: MethPrimers underestimate high DNA methylation. PLOS ONE, vol. 10:e0118318, p. 1-12, ISSN: 1932-6203, doi: 10.1371/journal.pone.0118318 PMID: 25692551
42. Luchetti A., Filareto A., Sanchez M., Ferraguti G., Lucarelli M., Novelli G., Sangiuolo F., Malgieri A. (2012). Small Fragment Homologous Replacement: Evaluation of Factors Influencing Modification Efficiency in an Eukaryotic Assay System. PLOS ONE, vol. 7, p. e30851, ISSN: 1932-6203, doi: 10.1371/journal.pone.0030851 PMID: 22359552
43. Ferraguti G., Pierandrei S., Bruno S. M., Ceci F., Strom R., Lucarelli M. (2011). A template for mutational data analysis of the CFTR gene. CLINICAL CHEMISTRY AND LABORATORY MEDICINE, vol. 49, p. 1447-1451, ISSN: 1434-6621, doi: 10.1515/cclm.2011.604 PMID: 21627495
44. Fuso A., Ferraguti G., Grandoni F., Ruggeri R., Scarpa S., Strom R., Lucarelli M. (2010). Early demethylation of non-CpG, CpC-rich, elements in the myogenin 5 '-flanking region A priming effect on the spreading of active demethylation? CELL CYCLE, vol. 9, p. 3965-3976, ISSN: 1538-4101, doi: 10.4161/cc.9.19.13193 PMID: 20935518
45. Narzi L., Ferraguti G., Stamato A., Narzi F., Valentini S.B., Lelli A., Delaroche I., Lucarelli M., Strom R., Quattrucci S. (2007). Does cystic fibrosis neonatal screening detect atypical CF forms? Extended genetic characterization and 4-year clinical follow-up. CLINICAL GENETICS, vol. 72, p. 39-46, ISSN: 0009-9163, doi: 10.1111/j.1399-0004.2007.00825.x PMID: 17594398
46. Lucarelli M., Narzi L., Piergentili R., Ferraguti G., Grandoni F., Quattrucci S., Strom R. (2006). A 96-well formatted method for exon and exon/intron boundary full sequencing of the CFTR gene. ANALYTICAL BIOCHEMISTRY, vol. 353, p. 226-235, ISSN: 0003-2697, doi: 10.1016/j.ab.2006.03.022 PMID: 16635477
47. Cardelli P., Scarpa S., Ceci F., Lucarelli M., Tabacco F., Ferraguti G., Brisdelli F., Strom R., Bozzi A. (2002). Effects of different oxidizing agents on neutral amino acid transport systems in isolated bovine brain microvessels. NEUROCHEMISTRY INTERNATIONAL, vol. 41, p. 29-36, ISSN: 0197-0186, doi: 10.1016/s0197-0186(01)00139-5 PMID: 11918969
48. Cardelli P., Fiori A., Corleto V.D., Savi M.R., Granata F., Ceci F., Ferraguti G., Potenza R.L., Delle Fave G., Jensen R.T., Strom R. (2001). Inhibitory effect of somatostatin on neutral amino acid transport in isolated brain microvessels. JOURNAL OF NEUROCHEMISTRY, vol. 78, p. 349-357, ISSN: 0022-3042, doi: 10.1046/j.1471-4159.2001.00412.x PMID: 11461970

In fede

Giampiero Ferraguti