Ritratto di alessandra.morano@uniroma1.it

Venerdì ore 15-16

Work experience

February 2019 Present
Neurologist responsible for Rehab Programme at ANFFAS Roma Onlus (Rehabilitation centre for people with intellectual disability), Rome, Italy

September 2018 - Present
Neuroscience and Psychiatry PhD student, Department of Human Neurosciences, Sapienza University of Rome, Rome, Italy

September 2018 Present
Neurologist at the Neurology and Epilepsy outpatient clinics, Department of Neurosciences/Mental Health, Policlinico Umberto I , Rome, Italy

August 2013 September 2018
Special registrat within the residency program in Neurology, Sapienza University of Rome, Rome, Italy

September 2011 August 2013
Attendance as a medical student at the Neurology and Epilepsy outpatient clinics, Department of Neurosciences/Mental Health, Policlinico Umberto I , Rome, Italy

Education and training
01.12.2021 present
Assistant Professor in Neurology, Department of Human Neurosciences, Sapienza University of
Rome, Rome, Italy

September 2018 present
Neuroscience and Psychiatry PhD programme, Department of Human Neurosciences, Sapienza University of Rome, Rome, Italy (ongoing) PhD Project Electro-clinical characterization of Autoimmune Encephalitis

24.11.18
High-level training course on Clinical Electromyography, Sapienza University of Rome, Rome, Italy

12.09.2018
Graduation in Neurology, Sapienza University of Rome, Rome, Italy
Thesis: Periventricular nodular heterotopia: electro-clinical and neuroimaging findings
Final Grade: 70/70 cum laude

29.02.2012
Enrollment to Albo dei Medici-Chirurghi of Matera (Medical license)

28.07.2011
Graduation in Medicine and Surgery, Sapienza University of Rome, Rome, Italy
Thesis: Novel therapeutic strategies for Status Epilepticus
Final grade: 110/110 cum laude

July 2005
High school graduation, Liceo Scientifico Enrico Fermi , Policoro (MT), Italy
Final grade: 100/100

Personal skills and competences

Mother tongue(s) Italian

Other language(s)
Self-assessment Understanding Speaking Writing
European level (*) Listening Reading Spoken interaction Spoken production
English Excellent Excellent Excellent Excellent Excellent

(*) Common European Framework of Reference for Languages

Social skills and competences Hardworking, outgoing person, with good attitude towards teamwork.
Remarkable empathy.

Organisational skills and competences

Technical skills and competences Trained in interpretation and referral of EEG/video-EEG/24-H Ambulatory EEG

Computer skills and competences Good knowledge of common computer programmes (Microsoft Office)

Publications
Generalized Fast Discharges Along the Genetic Generalized Epilepsy Spectrum: Clinical and Prognostic Significance . Cerulli Irelli E, Barone FA, Mari L, Morano A, Orlando B, Salamone EM, Marchi A, Fanella M, Fattouch J, Placidi F, Giallonardo AT, Izzi F, Di Bonaventura C. Front Neurol. 2022 Mar 10;13:844674. doi: 10.3389/fneur.2022.844674

Adjunctive Brivaracetam in Older Patients with Focal Seizures: Evidence from the BRIVAracetam add on First Italian netwoRk Study (BRIVAFIRST) . Lattanzi S, Canafoglia L, Canevini MP, Casciato S, Cerulli Irelli E, Chiesa V, Dainese F, De Maria G, Didato G, Falcicchio G, Fanella M, Ferlazzo E, Gangitano M, Giorgi FS, La Neve A, Mecarelli O, Montalenti E, Morano A, Piazza F, Pulitano P, Quarato PP, Ranzato F, Rosati E, Tassi L, Di Bonaventura C; BRIVAFIRST Group Membership. Drugs Aging. 2022 Mar 28. doi: 10.1007/s40266-022-00931-

Knowledge and attitudes of neurologists toward epilepsy surgery: an Italian survey . Casciato S*, Morano A*, Ricci L*, Asioli S, Barba C, Caulo M, Colicchio G, Cossu M, Consales A, de Palma L, Villani F, Zamponi N, Tassi L, Di Gennaro G, Beghi E, Marras CE. Neurol Sci. 2022 Mar 21:1-9.

Electroclinical Features and Long-term Seizure Outcome in Patients With Eyelid Myoclonia With Absences . Cerulli Irelli E, Cocchi E, Ramantani G, Caraballo RH, Giuliano L, Yilmaz T, Morano A, Panagiotakaki E, Operto FF, Giraldez BG, Silvennoinen K, Casciato S, Comajuan M, Balestrini S, Fortunato F, Coppola A, Di Gennaro G, Labate A, Sofia V, Kluger GJ, Kasteleijn-Nolst Trenité DGA, Gambardella A, Baykan B, Sisodiya SM, Arzimanoglou A, Striano P, Di Bonaventura C; EMA study group. Neurology. 2022 Mar 15:10.1212/WNL.0000000000200165.

Sustained seizure freedom with adjunctive brivaracetam in patients with focal onset seizures . Lattanzi S, Ascoli M, Canafoglia L, Paola Canevini M, Casciato S, Cerulli Irelli E, Chiesa V, Dainese F, De Maria G, Didato G, Di Gennaro G, Falcicchio G, Fanella M, Gangitano M, La Neve A, Mecarelli O, Montalenti E, Morano A, Piazza F, Pizzanelli C, Pulitano P, Ranzato F, Rosati E, Tassi L, Di Bonaventura C; BRIVAFIRST Group.

Olfactory impairment in autoimmune encephalitis: another piece of the puzzle . Morano A, Cerulli Irelli E, Fanella M, Orlando B, Salamone EM, Tinelli E, Ruffolo G, Zuliani L, Fattouch J, Manfredi M, Giallonardo AT, Di Bonaventura C. J Neurol. 2022 Jan 10:1-7. doi: 10.1007/s00415-022-10959-6

High rates of early remission pattern in adult-onset compared with earlier-onset idiopathic generalized epilepsy: A long-term follow-up study . Cerulli Irelli E, Orlando B, Salamone EM, Fisco G, Barone FA, Morano A, Fanella M, Fattouch J, Manfredi M, Giallonardo AT, Di Bonaventura C. Seizure. 2022 Jan;94:52-56. doi: 10.1016/j.seizure.2021.11.019.

Seizure outcome trajectories in a well-defined cohort of newly diagnosed juvenile myoclonic epilepsy patients . Cerulli Irelli E, Morano A, Orlando B, Salamone EM, Fanella M, Fattouch J, Manfredi M, Giallonardo AT, Di Bonaventura C. Acta Neurol Scand. 2021 Nov 17. doi: 10.1111/ane.13556

The grey zone between autoimmune encephalitis and autoimmune-associated epilepsy . Morano A, Cerulli Irelli E, Fanella M, Zuliani L, Giallonardo AT, Di Bonaventura C. Epilepsia Open. 2021 Nov 15. doi: 10.1002/epi4.12558

Camillo Negro (1861-1927) and Antonio Carle (1854-1927): Pioneers of non-resective surgical approach to epilepsy treatment . Brigo F, Di Gennaro G, Morano A, Sironi VA, Lorusso L; Study Group on the History of Neurology and of the Study Group on Epilepsy of the Italian Neurological Society. Epilepsy Behav. 2021 Oct 29;125:108360

Functional Gastrointestinal Disorders in Patients With Epilepsy: Reciprocal Influence and Impact on Seizure Occurrence . Avorio F, Cerulli Irelli E, Morano A, Fanella M, Orlando B, Albini M, Basili LM, Ruffolo G, Fattouch J, Manfredi M, Russo E, Striano P, Carabotti M, Giallonardo AT, Severi C, Di Bonaventura C. Front Neurol. 2021 Aug 6;12:705126

Reconsidering the role of selective sodium channel blockers in genetic generalized epilepsy . Cerulli Irelli E, Morano A, Fanella M, Orlando B, Salamone EM, Giallonardo AT, Di Bonaventura C. Acta Neurol Scand. 2021 Dec;144(6):647-65

Letter to the editor: focal non-convulsive status epilepticus manifesting as utilization behavior. Cerulli Irelli E, Fisco G, Morano A, Giallonardo AT, Di Bonaventura C. Neurol Sci. 2021 Sep;42(9):3885-3887. doi: 10.1007/s10072-021-05334-8.

"Dissecting the Molecular Determinants of GABAA Receptors Current Rundown, a Hallmark of Refractory Human pilepsy . Cifelli P, Di Angelantonio S, Alfano V, Morano A, De Felice E, Aronica E, Ruffolo G, Palma E.Brain Sci. 2021 Mar 30;11(4):441. doi: 10.3390/brainsci11040441

The surgical treatment of epilepsy . Consales A, Casciato S, Asioli S, Barba C, Caulo M, Colicchio G, Cossu M, de Palma L, Morano A, Vatti G, Villani F, Zamponi N, Tassi L, Di Gennaro G, Marras CE. Neurol Sci. 2021 Apr 2. doi: 10.1007/s10072-021-05198-y. Online ahead of print

Unilateral catalepsy in Nonconvulsive Status Epilepticus . Orlando B, Morano A, Cerulli Irelli E, Fanella M, Giallonardo AT, Di Bonaventura C. Epileptic Disord. 2021 Oct 1;23(5):760-764

Musicogenic epilepsy in paraneoplastic limbic encephalitis: a video-EEG case report . Morano A, Orlando B, Fanella M, Cerulli Irelli E, Colonnese C, Quarato P, Giallonardo AT, Di Bonaventura C. Epileptic Disord. 2021 Oct 1;23(5):754-759

Results from an Italian Expanded Access Program on Cannabidiol Treatment in Highly Refractory Dravet Syndrome and Lennox-Gastaut Syndrome . Iannone LF, Arena G, Battaglia D, Bisulli F, Bonanni P, Boni A, Canevini MP, Cantalupo G, Cesaroni E, Contin M, Coppola A, Cordelli DM, Cricchiuti G, De Giorgis V, De Leva MF, De Rinaldis M, D'Orsi G, Elia M, Galimberti CA, Morano A, Granata T, Guerrini
R, Lodi MAM, La Neve A, Marchese F, Masnada S, Michelucci R, Nosadini M, Pilolli N, Pruna D, Ragona F, Rosati A, Santucci M, Spalice A, Pietrafusa N, Striano P, Tartara E, Tassi L, Papa A, Zucca C, Russo E, Mecarelli O. Front Neurol 2021. Accepted for publication

Acute-onset binocular diplopia in neurological unit: Aetiological factors and diagnostic assessment . Cerulli Irelli E, Di Pietro G, Fisco G, Orlando B, Asci F, Salamone EM, Morano A, Di Bonaventura C. Acta Neurol Scand. 2021 Mar 31. doi: 10.1111/ane.13425. Online ahead of print

Water drinking behavior: a clinical clue for the diagnosis of limbic encephalitis in an elderly patient . Cerulli Irelli E, Di Pietro G, Asci F, Morano A, Di Bonaventura C. Acta Neurol Belg. 2021 Mar 8. doi: 10.1007/s13760-021-01633-1. Online ahead of print.

Clinical utility of home videos for diagnosing epileptic seizures: a systematic review and practical recommendations for optimal and safe recording . Ricci L, Boscarino M, Assenza G, Tombini M, Lanzone J, Di Lazzaro V, Casciato S, D'Aniello A, Morano A, Di Gennaro G; Epilepsy Study Group of the Italian Neurological Society. Neurol Sci. 2021 Apr;42(4):1301-1309. doi: 10.1007/s10072-021-05040-5

Persistent treatment resistance in genetic generalized epilepsy: A long term outcome study in a tertiary epilepsy center . Cerulli Irelli E, Morano A, Barone FA, Fisco G, Fanella M, Orlando B, Fattouch J, Manfredi M, Giallonardo AT, Di Bonaventura C. Epilepsia 2020. https://doi.org/10.1111/epi.16708

Seizures in autoimmune encephalitis: findings from an EEG pooled analysis . Morano A, Cerulli Irelli E, Barone FA, Fisco G, Orlando B, Fanella M, Albini M, Fattouch J, Manfredi M, Casciato S, Di Gennaro G, Giallonardo AT, Di Bonaventura C. Seizure. 2020;83:160-168.

Reduction in nosocomial infections during the COVID-19 era: a lesson to be learned . Cerulli Irelli E, Morano A, Di Bonaventura C.Updates Surg. 2020 Nov 19:1-2. doi: 10.1007/s13304-020-00925-0

Pharmacokinetic considerations about antiseizure medications in the elderly . Roberti R, Palleria C, Nesci V, Tallarico M, Di Bonaventura C, Cerulli Irelli E, Morano A, De Sarro G, Russo E, Citraro R. Expert Opin Drug Metab Toxicol. 2020 Sep 25:1-13. doi: 10.1080/17425255.2020.1806236.

The potential impact of enhanced hygienic measures during the COVID-19 outbreak on hospital-acquired infections: A pragmatic study in neurological units . Cerulli Irelli E, Orlando B, Cocchi E, Morano A, Fattapposta F, Di Piero V, Toni D, Ciardi MR, Giallonardo AT, Fabbrini G, Berardelli A, Di Bonaventura C. J Neurol Sci. 2020 Aug 29;418:117111. doi: 10.1016/j.jns.2020.117111.

Valproate impact and sex-dependent seizure remission in patients with idiopathic generalized epilepsy . Cerulli Irelli E, Cocchi E, Morano A, Casciato S, Fanella M, Albini M, Fisco G, Barone FA, Orlando B, Mascia A, Manfredi M, Fattouch J, Giallonardo AT, Di Gennaro G, Di Bonaventura C. J Neurol Sci. 2020 Aug 15;415:116940. doi: 10.1016/j.jns.2020.116940.

Post-Traumatic Meningitis Is a Diagnostic Challenging Time: A Systematic Review Focusing on Clinical and Pathological Features . La Russa R, Maiese A, Di Fazio N, Morano A, Di Bonaventura C, De Matteis A, Fazio V, Frati P, Fineschi V. Int J Mol Sci. 2020 Jun 10;21(11):4148. doi: 10.3390/ijms21114148.

Cannabinoids in the Treatment of Epilepsy: Current Status and Future Prospects . Morano A, Fanella M, Albini M, Cifelli P, Palma E, Giallonardo AT, Di Bonaventura C. Neuropsychiatr Dis Treat. 2020
Feb 7;16:381-396. doi: 10.2147/NDT.S203782.

Anxiety as the only manifestation of focal non-convulsive status epilepticus: case report and review of the literature . Albini M, Morano A, Fattouch J, Fanella M, Avorio F, Basili LM, Cerulli Irelli E, Manfredi M, Giallonardo AT, Di Bonaventura C. Neurocase. 2020 Apr;26(2):98-102. doi: 10.1080/13554794.2020.1741647.

An uncommon case of thunderclap headache in a patient with Marfan syndrome . Cerulli Irelli E, Morano A, Fanella M, Giallonardo AT, Di Bonaventura C. Acta Neurol Belg. 2020 May 4. doi: 10.1007/s13760-020-01364-9

Faciobrachial dystonic seizures: the borderland between epilepsy and movement disorders . Morano A, Fanella M, Giallonardo AT, Di Bonaventura C. Movement Disorders Clinical Practice. Accepted for publication. https://doi.org/10.1002/mdc3.12884

Doing without valproate in women of childbearing potential with idiopathic generalized epilepsy: Implications on seizure outcome . Cerulli Irelli E, Morano A, Cocchi E, Casciato S, Fanella M, Albini M, Avorio F, Basili LM, Fisco G, Barone FA, Mascia A, D'Aniello A, Manfredi M, Fattouch J, Quarato P, Giallonardo AT, Di Gennaro G, Di Bonaventura C. Epilepsia. 2019 Dec 11. doi: 10.1111/epi.16407.

Encephalopathy in a patient with loiasis treated with albendazole: A case report . Volpicelli L, De Angelis M, Morano A, Biliotti E, Franchi C, Gabrielli S, Mattiucci S, Di Bonaventura C, Taliani G. Parasitol Int. 2019 Oct 30;75:102006. doi: 10.1016/j.parint.2019.102006

Immediate and controlled-release pregabalin for the treatment of epilepsy . Morano A, Palleria C, Citraro R, Nesci V, De Caro C, Giallonardo AT, De Sarro G, Russo E, Di Bonaventura C. Expert Rev Neurother. 2019 Dec;19(12):1167-1177. doi: 10.1080/14737175.2019.1681265

The Evolution of Movement Disorders in N-Methyl-D-Aspartate Receptor Encephalitis-A Video Log . Morano A, Basili LM, Fanella M, Giallonardo AT, Di Bonaventura C. Mov Disord Clin Pract. 2019 Aug 16;6(7):610-611. doi: 10.1002/mdc3

Myoclonic epilepsy, parkinsonism, schizophrenia and left-handedness as common neuropsychiatric features in 22q11.2 deletion syndrome . Fanella M, Frascarelli M, Lambiase C, Morano A, Unolt M, Liberati N, Fattouch J, Buzzanca A, Accinni T, Ceccanti M, Viganò A, Biondi M, Colonnese C, Giallonardo AT, Di Fabio F, Pizzuti A, Di Bonaventura C, Berardelli A. J Med Genet. 2019 Sep 10. pii: jmedgenet-2019-106223. doi: 10.1136/jmedgenet-2019-106223

A Case of Ictal Epileptic Headache in Non Convulsive Status Epilepticus: Not Always, Not Only, a Matter of Pain . Fanella M, Morano A, Fattouch J, Albini M, Basili LM, Avorio F, Cerulli Irelli E, Manfredi M, Giallonardo AT, Di Bonaventura C. Headache. 2019 Jul;59(7):1090-1092. doi: 10.1111/head.13581.

Ictal atrial fibrillation during focal seizures: a case report and literature review . Basili LM, Morano A, Fattouch J, Fanella M, Albini M, Avorio F, Cerulli Irelli E, Manfredi M, Urani C, Strano S, Giallonardo AT, Di Bonaventura C. Epileptic Disord. 2019 Jun 1;21(3):295-301. doi: 10.1684/epd.2019.1070.

"Olfactory stimulus-induced temporal lobe seizures in limbic encephalitis . Avorio F, Morano A, Fanella M, Fattouch J, Albini M, Basili LM, Cerulli Irelli E, Fisco G, Manfredi M, Giallonardo AT, Di Bonaventura C. Seizure. 2019 Jul;69:204-206. doi: 10.1016/j.seizure.2019.05.005.

Pharmacology of new and developing intravenous therapies for the management of seizures and epilepsy . Morano A, Iannone L, Palleria C, Fanella M, Giallonardo AT, De Sarro G, Russo E, Di Bonaventura C. Expert Opin Pharmacother. 2018 Nov 7:1-15.

Perampanel as adjunctive therapy in highly refractory epilepsies: Real-world data from an Italian tertiary care epilepsy centre . Morano A, Fattouch J, Albini M, Casciato S, Fanella M, Basili LM, Viganò A, Manfredi M, Giallonardo AT, Di Bonaventura C. J Neurol Sci. 2018 Jul 15;390:67-74

A novel action of lacosamide on GABAA currents sets the ground for a synergic interaction with levetiracetam in treatment of epilepsy . Ruffolo G, Di Bonaventura C, Cifelli P, Roseti C, Fattouch J, Morano A, Limatola C, Aronica E, Palma E, Giallonardo AT. Neurobiol Dis. 2018 Jul;115:59-68.

Switch From Originator to Equivalent Drug in the Era of Generic Antiepileptic Drugs: Study of Keppra Versus Epitiram Clinical Equivalence . Fanella M, Morano A, Fattouch J, Albini M, Basili LM, Casciato S, Manfredi M, Giallonardo AT, Di Bonaventura C. Clin Neuropharmacol. 2017 Nov/Dec;40(6):239-242.

Factors underlying the development of chronic temporal lobe epilepsy in autoimmune encephalitis . Casciato S, Morano A, Fattouch J, Fanella M, Avorio F, Albini M, Basili LM, Cerulli Irelli E, Viganò A, DeRisi M, Grammaldo LG, D'Aniello A, Mascia A, Manfredi M, Quarato P, Giallonardo AT, Di Gennaro G, Di Bonaventura C. J Neurol Sci. 2018 Oct 30;396:102-107

Epileptic seizures heralding a relapse in high grade gliomas . Di Bonaventura C, Albini M, D'Elia A, Fattouch J, Fanella M, Morano A, Lucignani G, Manfredi M, Colonnese C, Salvati M, Vanacore N, Berardelli A, Giallonardo AT. Seizure. 2017 Oct;51:157-162.

Ictal pain in focal non-convulsive status epilepticus . Casciato S, Morano A, Fattouch J, Fanella M, Albini M, Giallonardo AT, Di Bonaventura C. Pract Neurol. 2017 Oct;17(5):400-402.

Ictal EEG/fMRI study of epileptic vertigo . Morano A, Carnì M, Casciato S, Vaudano AE, Fattouch J, Fanella M, Albini M, Basili LM, Scapeccia M, Lucignani G, Tomassi R, Di Castro E, Colonnese C, Giallonardo AT, Di Bonaventura C. Epilepsy Behav, 2017; Mar;68:51-56

Ictal Epileptic Headache in Occipital Symptomatic Epilepsy: Not Only a Matter of Cortex . Fanella M, Morano A, Fattouch J, Albini M, Basili LM, Casciato S, Manfredi M, Giallonardo AT, Di Bonaventura C. Headache. 2016 Dec 28. doi: 10.1111/head.13014.

Cannabis in epilepsy: From clinical practice to basic research focusing on the possible role of cannabidivarin . Morano A, Cifelli P, Nencini P, Antonilli L, Fattouch J, Ruffolo G, Roseti C, Aronica E, Limatola C, Di Bonaventura C, Palma E, Giallonardo AT. Epilepsia Open 2016, 1(3-4):145 151.

Behavioral and Movement Disorders due to Long-Lasting Myoclonic Status Epilepticus Misdiagnosed as ADHD in a Patient With Juvenile Myoclonic Epilepsy: Electroclinical Findings and Related Hemodynamic Changes . Fanella M, Carnì M, Morano A, Albini M, Lapenta L, Casciato S, Fattouch J, Di Castro E, Colonnese C, Vaudano AE, Giallonardo AT, Di Bonaventura C. Clin EEG Neurosci. 2016 Jan;47 (1):56-60.

Effectiveness of Rufinamide in the Treatment of Idiopathic Generalized Epilepsy With Atypical Evolution: Case Report and Review of the Literature . Albini M, Morano A, Fanella M, Lapenta L, Casciato S, Fattouch J, Manfredi M, Giallonardo AT, Di Bonaventura C. Clin EEG Neurosci. 2016 Apr;47(2):162-6.

Ictal epileptic headache in adult life: Electroclinical patterns and spectrum of related syndromes . Fanella M, Morano A, Fattouch J, Albini M, Manfredi M, Giallonardo AT, Di Bonaventura C. Epilepsy Behav. 2015 Dec;53:161-5.

Ictal epileptic headache revealing non convulsive status epilepticus in a case of eyelid myoclonia with absences . Fanella M, Morano A, Fattouch J, Albini M, Casciato S, Manfredi M, Giallonardo AT, Di Bonaventura C. J Headache Pain. 2015;16:105.

Cryptogenic focal epilepsy and "hidden" celiac disease in adulthood: a causal or accidental link? . Casciato S, Morano A, Albini M, Fanella M, Lapenta L, Fattouch J, Carnì M, Colonnese C, Manfredi M, Giallonardo AT, Di Bonaventura C. Int J Neurosci. 2015;125(12):913-7

Ambroxol-induced focal epileptic seizure . Lapenta L, Morano A, Fattouch J, Casciato S, Fanella M, Giallonardo AT, Di Bonaventura C. Clin Neuropharmacol. 2014 May-Jun;37(3):84-7.

Natural evolution from idiopathic photosensitive occipital lobe epilepsy to idiopathic generalized epilepsy in an untreated young patient . Bonini F, Egeo G, Fattouch J, Fanella M, Morano A, Giallonardo AT, di Bonaventura C. Brain Dev. 2014 Apr;36(4):346-50.

Clinical experience with intravenous valproate as first-line treatment of status epilepticus and seizure clusters in selected populations . Lapenta L, Morano A, Casciato S, Fanella M, Fattouch J, Vaudano AE, Gregori B, Vanacore N, Manfredi M, Giallonardo AT, Di Bonaventura C. Int J Neurosci. 2014 Jan;124(1):30-6.

The spectrum of epileptic syndromes with fixation off sensitivity persisting in adult life . Fattouch J, Casciato S, Lapenta L, Morano A, Fanella M, Lombardi L, Manfredi M, Giallonardo AT, Di Bonaventura C. Epilepsia. 2013 Oct;54 Suppl 7:59-65

Rome, 28/12/2019

Additional information
Oxcarbazepine-induced myoclonic status epilepticus in juvenile myoclonic epilepsy . Fanella M, Egeo G, Fattouch J, Casciato S, Lapenta L, Morano A, Giallonardo AT, Di Bonaventura C. Epileptic Disord. 2013 Jun;15(2):181-7.

Progressive myoclonic encephalopathies: From phenomenology to genes and proteins . Morano A, Di Bonaventura C. Basal Ganglia 2012 Dec, 2(4): 249-255.

Epilepsy, unawareness of seizures and driving license: the potential role of 24-hour ambulatory EEG in defining seizure freedom . Fattouch J, Di Bonaventura C, Lapenta L, Casciato S, Fanella M, Morano A, Manfredi M, Giallonardo AT. Epilepsy Behav. 2012 Sep;25(1):32-5.

Ictal epileptic headache as "subtle" symptom in generalized idiopathic epilepsy . Fanella M, Fattouch J, Casciato S, Lapenta L, Morano A, Egeo G, Manfredi M, Prencipe M, Giallonardo AT, Di Bonaventura C. Epilepsia. 2012 Apr;53(4):e67-70.

November 2019 November 2021
Italian Young Representative for European Academy of Neurology (EAN) Epilepsy Panel

2016 PRESENT
Member of Società Italiana di Neurologia (SIN) Epilepsy Study Group

2011 - PRESENT
Member of Lega Italiana Contro l Epilessia (LICE)

GCP certificate , CSSRS certificate, IATA certificate

Sub-investigator in several clinical trials

- Multicenter, post-marketing observational study AMPA. Promoter: EISAI

- Multi-center observational study Promoteo on drug-resistant epilepsy. Promoter: UCB Biopharma

- CRAD001M2X02B: An open-label, multi-center long-term safety roll-over study in patients with tuberous sclerosis complex (TSC) and refractory seizures who are judged by the Investigator to benefit from continued treatment with everolimus after completion of Study CRAD001M2304 (EXIST-3) . Sponsor: Novartis. Start date: 2017. Closed: Enrolled subjects: 1

- EP0091 A randomized, double-blind, placebo-controlled, dose finding study to evaluate the efficacy and safety of padsevonil as adjunctive treatment of focal-onset seizures in adult subjects with drug-resistant epilepsy. Phase II/III. Sponsor: UCB Pharma SA. Start date: 2018. Closed. Enrolled subjects: 6 (top enroller in Italy).

- EP0093 An open-label, multicenter, extension study to evaluate the safety and efficacy of Padsevonil as adjunctive treatment of focal-onset seizures in adult subjects with drug-resistant epilepsy phase 2/3 . Phase II/III. Sponsor: UCB Pharma SA. Start date: 2018. Closed. Enrolled subjects: 6 (top enroller in Italy).

-Open-label trial sponsored by LICE (Italian League Against Epilepsy) on Cannabidiol as off-label treatment in DS and LGS. Start date: 2019. Ongoing. Enrolled subjects: 3 (fixed number per site).

- XPF-008-201 A Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Safety, Tolerability and Efficacy of XEN1101 as Adjunctive Therapy in Focal-onset Epilepsy, with an Open-label Extension . Phase II/III. Sponsor: Xenopharmaceuticals. Start date: 22 Dec 2020. Ongoing. Enrolled subjects: 9 (top enroller in Italy).

-Deprepil: Effects of antidepressant treatment with agomelatine on patients affected by depression and epilepsy. A triple blind randomized study with active control (escitalopram),with parallel groups . Phase: IV. Promoter: Policlinico Tor Vergata , AIFA. Start Date: Sep 2020. Ongoing.

-GWEP20052:Cannabidiol (Epidyolex ®) in the treatment of Dravet- and Lennox Gasteaut
syndrome: A Retrospective chart review to Evaluate Independent effectiveness in clinical practice. Promoter: GW Research Ltd.

-EP0162: A double-blind, randomized, placebo-controlled, multicenter, outpatient, parallel-group study to assess the efficacy and safety of staccato alprazolam in participants 12 years of age and older with stereotypical prolonged seizures Promoter: UCB Biopharma SRL (in preparation)
- EP0165: An open-label multicenter, outpatient, extension study to evaluate the safety and tolerability of staccato alprazolam in participants 12 years of age and older with stereotypical prolonged seizures Promoter: UCB Biopharma SRL (in preparation)

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Rome, 08/04/2022