Ritratto di paola.bezzi@uniroma1.it
Insegnamento Codice Anno Corso - Frequentare Bacheca
FISIOLOGIA UMANA 10595547 2023/2024
FISIOLOGIA UMANA 1035576 2023/2024
FISIOLOGIA UMANA 1030629 2023/2024
FISIOLOGIA UMANA 10595547 2022/2023
FISIOLOGIA UMANA 1030629 2022/2023
FISIOLOGIA UMANA 1035576 2022/2023
FISIOLOGIA UMANA 10595547 2021/2022
FISIOLOGIA UMANA 1035576 2021/2022
FISIOLOGIA UMANA 1030629 2021/2022
FISIOLOGIA UMANA 1030629 2020/2021
FISIOLOGIA UMANA 1035576 2020/2021
FISIOLOGIA UMANA 1030629 2020/2021
FISIOLOGIA UMANA 1035576 2020/2021
FISIOLOGIA UMANA 1035576 2019/2020

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CURRENT POSITION Associate Professor, Department of Physiology and Pharmacology Vittorio Erspamer , La Sapienza University


1988 Maturité B, Bac Gymnase, Vigevano
1993 M. Sc. Biology, University of Pavia (Italy)
1998 Ph. D. Pharmacology, University of Milan (Italy)


1989-93 Biology, University of Pavia (Italy)
1993-98 PhD Pharmacology, University of Milan (Italy)

2004 « Imaging structure and function in the nervous system » (organized by: Karel Svoboda, Janelia Farm, USA and Frijtof Helmchen, ETH Zurich, Switzerland), Cold Spring Harbour Lab, NY, USA

1998-2001 Postgraduate Research Neuroscientist, Department Pharmacological Sciences, University of Milan, Italy
2001-2005 Postgraduate Research Neuroscientist, Department of Cell Biology and Morphology, University of Lausanne, Switzerland
2005- Junior Group Leader, Department of Cell Biology and Morphology, University of Lausanne, Switzerland
2009- Maitre d Enseignement et de Recherche 1 (PI/Senior Researcher), Department of Fundamental Neurosciences, University of Lausanne
2019- Associate Professor, La Sapienza University, Rome, Italy


1994-1998 Dean s Fellowship for PhD students, University of Milan
1998 Best presentation price, Italian Society of Neuroscience
2014 Best teacher first year of Medicine (LMT awards; FBM, UNIL)

Original reports last 5 years

1. Mitochondrial biogenesis in developing astrocytes regulates astrocyte maturation and synapse formation.
T Zehnder, F Petrelli, J Romanos, ECDO Figueiredo, TL Lewis Jr, N Déglon, F Polleux, M Santello, P Bezzi
Cell Reports, 2021

2. Tau accumulation in astrocytes of the dentate gyrus induces neuronal dysfunction and memory deficits in Alzheimer's disease.
Richetin K, Steullet P, Pachoud M, Perbet R, Parietti E, Maheswaran M, Eddarkaoui S, Bégard S, Pythoud C, Rey M, Caillierez R, Q Do K, Halliez S, Bezzi P, Buée L, Leuba G, Colin M, Toni N, Déglon N.
Nature Neurosci., 2020

3. Insights into the release mechanism of astrocytic glutamate evoking in neurons NMDA receptor-mediated slow depolarizing inward currents.
Gómez-Gonzalo M, Zehnder T, Requie LM, Bezzi P, Carmignoto G.
Glia, 2018

4. Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments.
Petrelli F, Dallérac G, Pucci L, Calì C, Zehnder T, Sultan S, Lecca S, Chicca A, Ivanov A, Asensio CS, Gundersen V, Toni N, Knott GW, Magara F, Gertsch J, Kirchhoff F, Déglon N, Giros B, Edwards RH, Mothet JP, Bezzi P.
Mol Psychiatry., 2020 (Cover)

5. SHANK3 controls maturation of social reward circuits in the VTA.
Bariselli S, Tzanoulinou S, Glangetas C, Prévost-Solié C, Pucci L, Viguié J, Bezzi P, O'Connor EC, Georges F, Lüscher C, Bellone C.
Nature Neurosci., 2016

6. Homer1 Scaffold Proteins Govern Ca2+ Dynamics in Normal and Reactive Astrocytes.
Buscemi L, Ginet V, Lopatar J, Montana V, Pucci L, Spagnuolo P, Zehnder T, Grubi i V, Truttman A, Sala C, Hirt L, Parpura V, Puyal J, Bezzi P.
Cereb Cortex, 2017

7. Synaptic Integration of Adult-Born Hippocampal Neurons Is Locally Controlled by Astrocytes.
Sultan S, Li L, Moss J, Petrelli F, Cassé F, Gebara E, Lopatar J, Pfrieger FW, Bezzi P, Bischofberger J, Toni N.
Neuron, 2016

8. G-protein coupled receptor-evoked glutamate exocytosis from astrocytes: role of prostaglandins.
Cali C, Lopatar J, Petrelli F, Pucci L, Bezzi P.
Neural Plast., 2014

1. Reviews last 5 years

1. mGlu5-mediated signalling in developing astrocyte and the pathogenesis of autism spectrum disorders.
Petrelli F, Bezzi P.
Curr Opin Neurobiol., 2018

2. Astrocytes and Microglia and Their Potential Link with Autism Spectrum Disorders.
Petrelli F, Pucci L, Bezzi P.
Front Cell Neurosci., 2016

3. Novel insights into gliotransmitters.
Petrelli F, Bezzi P.
Curr Opin Pharmacol., 2016

4. Understanding the multifaceted role of inflammatory mediators in ischemic stroke
Amantea D, Tassorelli C, Petrelli F, Certo M, Bezzi P, Micieli G, Corasaniti MT, Bagetta G. Curr Med Chem., 2013