Corso di fisica II per Ingegneria Clinica:
Il corso iniziera' Lunedi' 27 Settembre. L'orario si puo'consulare all'URL :
Potranno essere in presenza solo gli studenti che si sono registati su ProDigit.
Le lezioni saranno visibili in remoto tramite piattaforma ZOOM, collegandosi con la stanza ZOOM relativa all'aula 14 e 16 di via scarpa
Ho aperto una classe di Classrom relativa a questo corso, raggiungibile tramite il seguente link di Classrom:
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Education Academic Achievements
2018 Full Professor at University of Roma La Sapienza
2018 Appointed with the Italian ASN National scientific qualification for FIS/07- 01/D1 scientific sector (Applied physics)
2014 Appointed with the Italian ASN National scientific qualification for FIS/01- 01/A2 scientific sector (Particle Physics)
2010-2018 Associate Professor at Base and Applied Science for Engineering Department of Rome University La Sapienza
1999-2010 Associate Professor at Energetics Department of Rome University La Sapienza
1992-1999 Permanent Researcher at Energetics Department of Rome University "La Sapienza
1992 Visiting Researcher at California Institute of Technology.
1990-1992 Permanent Researcher at Istituto Nazionale di Fisica Nucleare (INFN) at Frascati National Laboratory (LNF)
1988-1989 Research grant of INFN at Frascati National Laboratory
1987 Degree in Elementary Particle Physics: 110/110 cum laude at Rome University "La Sapienza
2019-now Spokeperson of the International Biophysics Collaboration (more than 200 researchers from 20 Countries)
2019-now Deputy Director of the Specialty School of Medical Physics at the University of Rome La Sapienza
2018-now PI of the Flagship Project (Progetto Premiale) of the MIUR (Italian Ministry of Education, University and Research) for the Centro Fermi Research Institute: SPARE: Space Radiation Shielding
2016-now Spokesperson of the FOOT (FragmentatiOn Of Target) international collaboration (France, Germany, Italy, Japan)
2016-now Coordinator of the Working Package 5 Charged detector for Imaging in Particle Therapy of the European Nuclear Science and Applications Research (ENSAR-2) -MediNet project.
2014-2016 Principal Investigator (PI) of the NCS@HIT experiment at Heidelberg Ion-Beam Therapy Center (HIT) funded by the Union of Light Ion Centers in Europe (ULICE) Program for the study of the beam fragmentation in Particle Therapy
2012-2015 PI of the Flagship Project (Progetto Premiale) of the MIUR (Italian Ministry of Education, University and Research) for the Centro Fermi Research Institute: Multiple source, real-time Imaging for Hadrontherapy
2012-2015 PI at La Sapienza University of Rome of the PRIN project (Research Project of National Relevance) INSIDE: Innovative Solution of Imaging and Dosimetry in Hadrontherapy
2012-2016 PI of the INFN experiment RDH (R&D in Hadrontherapy) at Roma1 section
2012-now PI of the project of the Centro Fermi Research Institute: Innovative non invasive imaging of dose release in hadrontherapy
2010-2015 Spokesperson of the FIRST-S361 (Fragmentation of Ions Relevant for Space and Therapy) international collaboration at GSI laboratory (Darmstadt, Germany)
2009-2012 PI of the INFN project TPS (Treatment Planning System for hadrontherapy) at Frascati National Laboratory of INFN
2006-2009 PI at La Sapienza University of Rome of the PRIN project on Read-out optimization and DAQ electronics development of a scintillating fiber tracking calorimeter
2019- Chair of the BIO-PAC selection panel at GSI
2019- Chair of the User selection Panel of the Beam Test Facility (BTF) of Laboratori Nazionali di Frascati (LNF)
2018- Users selection Panel of the Beam Test Facility (BTF) of Laboratori Nazionali di Frascati (LNF)
2017 Committee for the assignment of the INFN post-doc fellowships for foreigners
2016-2019 Committee for the assignment of the INFN post-doc fellowships at Roma 1 section.
2013-now Ph.D. School in Accelerator Physics at Rome University La Sapienza
2015-now Specialization School in Medical Physics at Rome University La Sapienza
2012-2014 Users Committee of Laboratori Nazionali del Sud (LNS)
2010-2014 Scientific Committee of FLUKA international collaboration
2008-now Policy Board of KLOE-2 (K Long Experiment) experiment at LNF
2006-2009 Panel for TARI (Transnational Access to Research Infrastracture) funds assignment of the European Network of Underground Laboratories
2004-2018 Jury for PhD thesis examination at University of Rome La Sapienza , University of Rome Tor Vergata , University of Rome Tre , University of Milano, University of Napoli and University of Torino
2004-2007 Committee for permanent researcher positions in experimental physics (FIS/01) at Perugia and Lecce Universities
2003-2009 Panel for TARI funds assignment of Laboratori Nazionali del Gran Sasso (LNGS) of INFN
2002-2005 Executive Committee of the Energetics Department of Rome University La Sapienza .
2001-2007 Scientific Committee of LNGS of INFN
Referee for DFG (German Research Foundation), KWF (Dutch Cancer Society)
Referee for MIUR (Italian Ministry of Education, University and Research): VQR (Research Evaluation) 2004-2010, VQR 2011-2014, PRIN and FIRB (Futuro In Ricerca) research project, CIVR (Comitato di Indirizzo per la Valutazione della Ricerca), FARE (Framework per l Attrazione e il Rafforzamento della Ricerca) research projects of MIUR.
Reviewer of International Scientific Journals : Scientific Reports, Physics in Medicine and Biology, Physica Medica, Medical Physics, Journal of Radiation Research, Nuclear Instruments and Methods, Translational Cancer Research, Frontiers in Oncology, Journal of Radiation Oncology, Advances in Physics, Transaction of Nuclear Science, IEEE Transactions on Radiation and Plasma Medical Sciences
Editor of the Special Issue of Frontiers in Physics (2020) : Applied Nuclear Physics at Accelerators
Teaching and Training activities
Teaching activity took place within the Faculty of Engineering of the University of Rome Sapienza since 1995 until 2020. V.P. was the professor of courses of General Physics II (Electromagnetism), General Physics I (Mechanics and Thermodynamics), Laboratory of Physics, Modern Physics, Radioprotection, Radiation Physics applied to Medicine.
Supervisor of more 34 thesis in the faculty of Engineering and of Mathematical, Physical and Natural Science of the Rome University "Sapienza".
Supervisor of 9 Ph.D. thesis of University of Rome "Sapienza", of University of Rome "Tor Vergata" and University "ROMA 3".
Supervisor of post-doc contracts funded by University "Sapienza", by INFN, by Centro Fermi Research Institute and by Istituto Italiano di Tecnologia (IIT)
Seminars and Conference Talks in the last five years
Invited talk: Nuclear Physics Application in cancer therapy with light ion beams , Israel-Italy Scientific Workshop in particle accelerator: development and Uses in Medical Application, 2019 Tel Aviv
Seminar: Measuring the fragmentation cross section with the FOOT experiment , CCAP Seminar, Imperial College, 2019 London
Invited talk: FOOT: a nuclear physics experiment focused on Particle therapy and Radioprotection in Space , 3rd Jagellonian Symposium on Fundamental and Applied Subatomic Physics, Krakow, 2019
Invited talk Nuclear fragmentation and Particle Therapy , SPES Workshop , Ferrara, 2019
Seminar: Nuclear Interaction and Particle Therapy , Trento University, Trento, 2018
Invited talk Vision for: beam tracking with prompt secondary ions , 3rd Heidelberg Symposium on Novel Techniques in Ion Beam Radiotherapy, Heidelberg, 2018
Seminar: The FOOT (FragmentatiOn Of Target) experiement , GSI Biophysics seminar Darmstadt, 2018
Invited talk: FOOT FragmentatiOn Of Target experiment at PRESS: PRoton thErapy research SeminarS, Krakow, 2017
Talk: Foot, an experiment for the measurement of the nuclear fragmentation in Particle Therapy , International Nuclear Physics Conference Adelaide, 2016
Invited talk: Novel developments in imaging and dosimetry for Hadrontherapy , 54th Int. Winter Meeting on Nuclear Physics Bormio, 2016
Seminar: Nuclear aspects in hadrontherapy at Universisty of Tor Vergata, Rome, 2015
Invited talk: What are the new challenges in Particle Therapy? , IFD2015 workshop, Torino, 2015
Invited talk: Nuclear Fragmentation and Particle therapy , 101 Congress of Italian Physics Society, Rome, 2015
GSI Kolloquium: Nuclear aspects in hadrontherapy at GSI, Darmstdt, 2015
Publication Summary: 356 Papers, 7910 Citations, 47 H index (Source Scopus)
Summary of Research Activities
a) 2008-2020: Physics applied to particle therapy and to medical imaging
In 2009 V.P. promoted the birth, and since then coordinates, a group aiming at developing cutting-edge applications of nuclear and particle physics in the field of medical diagnostics and therapy.
This group includes members from "La Sapienza" University of Rome and from Centro Fermi Research Institute, and is collaborating with the GSI Laboratory (Darmstadt, Germany), the HIT Therapy Center (Heidelberg, Germany), the CNAO Centro Nazionale di Adroterapia Oncologica (Pavia, Italy), the IFJ PAN Proton Therapy Center (Krakow, Poland) and with the APSS Proton Therapy Center (Trento, Italy). The group has very close collaborations with several sections of INFN (Bo, LNS, LNF, Mi, Na, Pi, RM2, TIFPA, To).
The group focused on nuclear techniques related with the use of proton and carbon beams for tumor treatment:
Evaluation of the effects of the ion beam fragmentation in the patient, both in carbon treatment (projectile fragmentation) and proton treatment (target fragmentation). V.P. has been the spokesperson of two international collaborations addressing this issue: S371-FIRST (Fragmentation of Ions Relevant for Space and Therapy; Germany, France, Italy), which took data at GSI in 2011-2012, and the FOOT (FragmentatiOn Of Target) (Germany, France, Japan and Italy), which at present is in construction. The FOOT experiment has been included in the NUPEC 2017 roadmap and has been included in the European Space Agency research program for radioprotection on space
Imaging optimization of the dose release in particle therapy treatment. Beam range monitoring during the treatment is one of the major improvement of the quality assurance of the treatment. It can be achieved exploiting the neutral and charged secondary flux produced by the interaction of the beam with the patient tissue. Due the absence of data about the secondary production V.P. had been the PI of the design, construction, data taking, data analysis, and simulation of several measurement campaigns at LNS, GSI, HIT, CNAO and TIFPA.
The study of the secondary emission provided the V.P. group with the knowledge necessary for the design of an on-line beam range monitor device, to be used at CNAO. This device is made of a compact tracker to detect charged secondary emission allowing on-line monitoring of carbon beam range. The group led by V.P. designed and built the detector, the front-end electronics, the data acquisition and an innovative on-line reconstruction technique. This activity has been carried out initially within the INSIDE PRIN project and then within the Centro Fermi Project dedicated to the Particle Therapy technology development, in both cases with V.P. as PI.
V.P. has been deeply involved in Monte Carlo software development applied to medical physics and radioprotection, notably to its use in developing the Treatment Planning System in particle therapy. Such an activity has been carried out within the INFN-CERN FLUKA collaboration (V.P. is a contributing author of the FLUKA code) and within the INFN-TPS collaboration, which produced a commercial Treatment Planning System for carbon and proton. V.P. is coordinating the development of the FRED (Fast paRticle thErapy Dose evaluator) Monte Carlo software that computes on GPU the dose released to the patient by a proton beam reducing the CPU time of two orders of magnitude. That software is under test at CNAO center and routinely used at IFJ PAN (Krakow) and MAASTRO (Maastricht) proton therapy centers.
A parallel research stream has been focused on the development of an innovative intraoperative probe for brain surgery in oncology. Such an intraoperative tool, which effectively detects tumor margins in real time, could be a useful surgical adjunct for brain tumor resection. That work provided V.P. of a patent about Intraoperative detection of tumor residues using - radiation and corresponding probes, N.PCT/IT2014/000025
b) 1993-today. Study of fundamental discrete symmetries of sub-nuclear interaction and of the quark mixing matrix unitarity.
This research took place within the international KLOE collaboration, that designed and built an apparatus optimized for the study of discrete symmetries (parity inversion, time inversion and charge conjugation) in the quantum system of charged and neutral kaon pairs generated in the decay at rest of phi mesons, and of the unitarity test of the quark mixing matrix (CKM). The KLOE data taking at the DAPHNE electron-positron collider of the Frascati National Laboratory of INFN ended in april 2006.
The contribution of the candidate to the detector was first focused in the design of the charged particle trigger system and in the development of the simulation and reconstruction software of the drift chamber. V.P. was also the coordinator of the analysis group that studied the charged kaon physics. This activity updated all the charged kaon branching ration in literature and led to an updated determination of the Vus element of the CKM quark mixing matrix.
In 2008 V.P. has become a member of Policy Board of the KLOE2 collaboration that extended the KLOE physics program at the renewed DAPHNE machine with an upgraded detector.
c) 1987-2004 Study of high energy penetrating cosmic rays
The main effort in this field was carried out within the MACRO experiment, hosted in Hall B of the underground laboratories of Gran Sasso (INFN) and conducted by an Italy-US collaboration. The aims of this experiment were the study of the penetrating cosmic radiation, the search for neutrinos from stellar collapses inside our galaxy, and the possible detection of magnetic monopoles of cosmological origin.
The MACRO detector was optimized for the detection of magnetic monopoles. V.P. carried out the computation of the interaction probability (and the tracking efficiency) of the slow monopoles in the MACRO tracking system, providing an important contribution to the monopole flux limit determination.
|Insegnamento||Codice||Anno||Corso - Frequentare|
|FISICA II||1015381||2021/2022||Ingegneria Clinica|
|FISICA DELLE RADIAZIONI APPLICATA ALLA MEDICINA||1044765||2021/2022||Ingegneria Biomedica|
|FISICA II||1015381||2020/2021||Ingegneria Meccanica|
|FISICA II||1015381||2020/2021||Ingegneria Clinica|
|FISICA DELLE RADIAZIONI APPLICATA ALLA MEDICINA||1044765||2020/2021||Ingegneria Biomedica|
|FISICA II||1015381||2019/2020||Ingegneria Meccanica|
|FISICA II||1015381||2019/2020||Ingegneria Clinica|
|FISICA DELLE RADIAZIONI APPLICATA ALLA MEDICINA||1044765||2019/2020||Ingegneria Biomedica|
|FISICA II||1015381||2018/2019||Ingegneria Meccanica|
|FISICA II||1015381||2018/2019||Ingegneria Clinica|
|FISICA DELLE RADIAZIONI APPLICATA ALLA MEDICINA||1044765||2018/2019||Ingegneria Biomedica|
|FISICA DELLE RADIAZIONI APPLICATA ALLA MEDICINA||1044765||2017/2018||Ingegneria Biomedica|
|FISICA II||1015381||2017/2018||Ingegneria Clinica|
|FISICA II||1015381||2017/2018||Ingegneria Meccanica|
|FISICA DELLE RADIAZIONI APPLICATA ALLA MEDICINA||1044765||2016/2017||Ingegneria Biomedica|
|FISICA II||1015381||2016/2017||Ingegneria Meccanica|
|FISICA II||1015381||2016/2017||Ingegneria Clinica|
|The drift chamber detector of the FOOT experiment: Performance analysis and external calibration||NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH. SECTION A, ACCELERATORS, SPECTROMETERS, DETECTORS AND ASSOCIATED EQUIPMENT||2021|
|Compact S-band linear accelerator system for ultrafast, ultrahigh dose-rate radiotherapy||PHYSICAL REVIEW. ACCELERATORS AND BEAMS||2021|
|Charge identification of nuclear fragments with the FOOT Time-Of-Flight system||NUCLEAR INSTRUMENTS AND METHODS IN PHYSICS RESEARCH. SECTION A, ACCELERATORS, SPECTROMETERS, DETECTORS AND ASSOCIATED EQUIPMENT||2021|
|PAPRICA: The Pair Production Imaging Chamber—Proof of Principle||FRONTIERS IN PHYSICS||2021|
|Measuring the Impact of Nuclear Interaction in Particle Therapy and in Radio Protection in Space: the FOOT Experiment||FRONTIERS IN PHYSICS||2021|
|Measurement of the branching fraction for the decay KS → πμν with the KLOE detector||PHYSICS LETTERS. SECTION B||2020|
|Development of a novel neutron tracker for the characterisation of secondary neutrons emitted in Particle Therapy||NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH. SECTION A, ACCELERATORS, SPECTROMETERS, DETECTORS AND ASSOCIATED EQUIPMENT||2020|
|TOPS project: Development of new fast timing plastic scintillators.||IL NUOVO CIMENTO C||2020|
|Upper limit on the η → π + π − branching fraction with the KLOE experiment||JOURNAL OF HIGH ENERGY PHYSICS||2020|
|The MONDO tracker: characterisation and study of secondary ultrafast neutrons production in carbon ion radiotherapy||FRONTIERS IN PHYSICS||2020|
|Inter-fractional monitoring of 12 C ions treatments: results from a clinical trial at the CNAO facility||SCIENTIFIC REPORTS||2020|
|FRED: A fast Monte Carlo code on GPU for quality control in particle therapy||JOURNAL OF PHYSICS. CONFERENCE SERIES||2020|
|Performance of the ToF detectors in the foot experiment||IL NUOVO CIMENTO C||2020|
|Recent Advances in Detector Technologies for Particle Therapy Beam Monitoring and Dosimetry||IEEE TRANSACTIONS ON RADIATION AND PLASMA MEDICAL SCIENCES||2020|
|Review and performance of the Dose Profiler, a particle therapy treatments online monitor||PHYSICA MEDICA||2019|
|Secondary radiation measurements for particle therapy applications: Charged secondaries produced by 16O ion beams in a PMMA target at large angles||PHYSICA MEDICA||2019|
|Development and characterization of a ΔE-TOF detector prototype for the FOOT experiment||NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH. SECTION A, ACCELERATORS, SPECTROMETERS, DETECTORS AND ASSOCIATED EQUIPMENT||2019|
|Ion charge separation with new generation of nuclear emulsion films||OPEN PHYSICS||2019|
|A 16 × 8 Digital-SiPM Array with Distributed Trigger Generator for Low SNR Particle Tracking||2019|
|The MONDO detector prototype development and test: steps towards a SPAD-CMOS based integrated readout (SBAM sensor)||IEEE TRANSACTIONS ON NUCLEAR SCIENCE||2018|