Medical Biotechnology

Educational objectives

Module of Biochemistry and Structural Biology:

Learning the usage of the major protein-related methodologies aimed at the analysis of proteins’ structure.
Learning main tools of proteomics analysis and recognizing available data, with special attention to their limitations.
Being able to 1) measure the thermodynamic stability , 2) define the mechanism of folding of small proteins, 3) measure binding affinity. Describing mechanisms of intermolecular recognition. Describing mechanisms of aggregation and fibrillogenesis. Knowing the principles of de novo protein design.
Acquiring capacity of critical reading of scientific papers.

Module of Bioinformatics and proteine engineering:

Learning bioinformatics data and tools, with special attention to their limitations
Being able to correctly use bioinformatics tools, with special attention to proteomic studies
To learn the general principles of the design, production and mutagenesis of proteins
Acquiring capacity of critical reading of scientific papers.

Educational objectives

Module of Biochemistry and Structural Biology:

Learning the usage of the major protein-related methodologies aimed at the analysis of proteins’ structure.
Learning main tools of proteomics analysis and recognizing available data, with special attention to their limitations.
Being able to 1) measure the thermodynamic stability , 2) define the mechanism of folding of small proteins, 3) measure binding affinity. Describing mechanisms of intermolecular recognition. Describing mechanisms of aggregation and fibrillogenesis. Knowing the principles of de novo protein design.
Acquiring capacity of critical reading of scientific papers.

Module of Bioinformatics and proteine engineering:

Learning bioinformatics data and tools, with special attention to their limitations
Being able to correctly use bioinformatics tools, with special attention to proteomic studies
To learn the general principles of the design, production and mutagenesis of proteins
Acquiring capacity of critical reading of scientific papers.

Educational objectives

Module of Biochemistry and Structural Biology:

Learning the usage of the major protein-related methodologies aimed at the analysis of proteins’ structure.
Learning main tools of proteomics analysis and recognizing available data, with special attention to their limitations.
Being able to 1) measure the thermodynamic stability , 2) define the mechanism of folding of small proteins, 3) measure binding affinity. Describing mechanisms of intermolecular recognition. Describing mechanisms of aggregation and fibrillogenesis. Knowing the principles of de novo protein design.
Acquiring capacity of critical reading of scientific papers.

Module of Bioinformatics and proteine engineering:

Learning bioinformatics data and tools, with special attention to their limitations
Being able to correctly use bioinformatics tools, with special attention to proteomic studies
To learn the general principles of the design, production and mutagenesis of proteins
Acquiring capacity of critical reading of scientific papers.

Educational objectives

Module of Biochemistry and Structural Biology:

Learning the usage of the major protein-related methodologies aimed at the analysis of proteins’ structure.
Learning main tools of proteomics analysis and recognizing available data, with special attention to their limitations.
Being able to 1) measure the thermodynamic stability , 2) define the mechanism of folding of small proteins, 3) measure binding affinity. Describing mechanisms of intermolecular recognition. Describing mechanisms of aggregation and fibrillogenesis. Knowing the principles of de novo protein design.
Acquiring capacity of critical reading of scientific papers.

Module of Bioinformatics and proteine engineering:

Learning bioinformatics data and tools, with special attention to their limitations
Being able to correctly use bioinformatics tools, with special attention to proteomic studies
To learn the general principles of the design, production and mutagenesis of proteins
Acquiring capacity of critical reading of scientific papers.

Educational objectives

The course aims to provide knowledge of i) the molecular mechanisms controlling physiological cellular functions (e.g., cell proliferation, death, senescence, differentiation), ii) how the cell regulates these functions in response to stimuli from the tissue microenvironment, iii) how it integrates these signals in order to contribute to the tissue homeostasis, iv) the alterations found in different physio-pathological conditions. The neoplastic transformation will be used as a paradigm of deregulations involving multi-level cellular function, and the liver as example of organ for physio-pathological studies. The student, once acquired knowledge of the mechanisms that regulate cell functions, will acquire skills to propose experimental approaches for the analysis of these functions both in vitro and in vivo.
These skills will be developed through simulations of scientific problems in interactive lessons, where students will develop critical skills, will apply the acquired knowledge and will discuss collectively the possible experimental approaches for their solving.

Educational objectives

The course aims to provide knowledge of i) the molecular mechanisms controlling physiological cellular functions (e.g., cell proliferation, death, senescence, differentiation), ii) how the cell regulates these functions in response to stimuli from the tissue microenvironment, iii) how it integrates these signals in order to contribute to the tissue homeostasis, iv) the alterations found in different physio-pathological conditions. The neoplastic transformation will be used as a paradigm of deregulations involving multi-level cellular function, and the liver as example of organ for physio-pathological studies. The student, once acquired knowledge of the mechanisms that regulate cell functions, will acquire skills to propose experimental approaches for the analysis of these functions both in vitro and in vivo.
These skills will be developed through simulations of scientific problems in interactive lessons, where students will develop critical skills, will apply the acquired knowledge and will discuss collectively the possible experimental approaches for their solving.

Educational objectives

The course aims to provide knowledge of i) the molecular mechanisms controlling physiological cellular functions (e.g., cell proliferation, death, senescence, differentiation), ii) how the cell regulates these functions in response to stimuli from the tissue microenvironment, iii) how it integrates these signals in order to contribute to the tissue homeostasis, iv) the alterations found in different physio-pathological conditions. The neoplastic transformation will be used as a paradigm of deregulations involving multi-level cellular function, and the liver as example of organ for physio-pathological studies. The student, once acquired knowledge of the mechanisms that regulate cell functions, will acquire skills to propose experimental approaches for the analysis of these functions both in vitro and in vivo.
These skills will be developed through simulations of scientific problems in interactive lessons, where students will develop critical skills, will apply the acquired knowledge and will discuss collectively the possible experimental approaches for their solving.

Educational objectives

Module of Biochemistry and Structural Biology:

Learning the usage of the major protein-related methodologies aimed at the analysis of proteins’ structure.
Learning main tools of proteomics analysis and recognizing available data, with special attention to their limitations.
Being able to 1) measure the thermodynamic stability , 2) define the mechanism of folding of small proteins, 3) measure binding affinity. Describing mechanisms of intermolecular recognition. Describing mechanisms of aggregation and fibrillogenesis. Knowing the principles of de novo protein design.
Acquiring capacity of critical reading of scientific papers.

Module of Bioinformatics and proteine engineering:

Learning bioinformatics data and tools, with special attention to their limitations
Being able to correctly use bioinformatics tools, with special attention to proteomic studies
To learn the general principles of the design, production and mutagenesis of proteins
Acquiring capacity of critical reading of scientific papers.

Educational objectives

Module of Biochemistry and Structural Biology:

Learning the usage of the major protein-related methodologies aimed at the analysis of proteins’ structure.
Learning main tools of proteomics analysis and recognizing available data, with special attention to their limitations.
Being able to 1) measure the thermodynamic stability , 2) define the mechanism of folding of small proteins, 3) measure binding affinity. Describing mechanisms of intermolecular recognition. Describing mechanisms of aggregation and fibrillogenesis. Knowing the principles of de novo protein design.
Acquiring capacity of critical reading of scientific papers.

Module of Bioinformatics and proteine engineering:

Learning bioinformatics data and tools, with special attention to their limitations
Being able to correctly use bioinformatics tools, with special attention to proteomic studies
To learn the general principles of the design, production and mutagenesis of proteins
Acquiring capacity of critical reading of scientific papers.

Educational objectives

Module of Biochemistry and Structural Biology:

Learning the usage of the major protein-related methodologies aimed at the analysis of proteins’ structure.
Learning main tools of proteomics analysis and recognizing available data, with special attention to their limitations.
Being able to 1) measure the thermodynamic stability , 2) define the mechanism of folding of small proteins, 3) measure binding affinity. Describing mechanisms of intermolecular recognition. Describing mechanisms of aggregation and fibrillogenesis. Knowing the principles of de novo protein design.
Acquiring capacity of critical reading of scientific papers.

Module of Bioinformatics and proteine engineering:

Learning bioinformatics data and tools, with special attention to their limitations
Being able to correctly use bioinformatics tools, with special attention to proteomic studies
To learn the general principles of the design, production and mutagenesis of proteins
Acquiring capacity of critical reading of scientific papers.

Educational objectives

Module of Biochemistry and Structural Biology:

Learning the usage of the major protein-related methodologies aimed at the analysis of proteins’ structure.
Learning main tools of proteomics analysis and recognizing available data, with special attention to their limitations.
Being able to 1) measure the thermodynamic stability , 2) define the mechanism of folding of small proteins, 3) measure binding affinity. Describing mechanisms of intermolecular recognition. Describing mechanisms of aggregation and fibrillogenesis. Knowing the principles of de novo protein design.
Acquiring capacity of critical reading of scientific papers.

Module of Bioinformatics and proteine engineering:

Learning bioinformatics data and tools, with special attention to their limitations
Being able to correctly use bioinformatics tools, with special attention to proteomic studies
To learn the general principles of the design, production and mutagenesis of proteins
Acquiring capacity of critical reading of scientific papers.

Educational objectives

At the end of the course students should:

- be able to identify and discuss ethical issues in life sciences and to provide argumentations in ethical decision-making,
- have acquired knowledge in biolaw and soft law.
- know the basic elements of the operating characteristics of a company, of the techniques to build a business plan and of the characteristics of innovative companies with high technological content
- know the legislation on health and safety at work in the biotechnology sector.
- know the ISO Standards on Quality Systems (ISO 9001, Standard Certification, ISO 17025 Standard Accreditation test laboratories)
- to know structured and reproducible methods for the acquisition of scientific evidence and the quality evaluation of studies.

Educational objectives

At the end of the course students should:

- be able to identify and discuss ethical issues in life sciences and to provide argumentations in ethical decision-making,
- have acquired knowledge in biolaw and soft law.
- know the basic elements of the operating characteristics of a company, of the techniques to build a business plan and of the characteristics of innovative companies with high technological content
- know the legislation on health and safety at work in the biotechnology sector.
- know the ISO Standards on Quality Systems (ISO 9001, Standard Certification, ISO 17025 Standard Accreditation test laboratories)
- to know structured and reproducible methods for the acquisition of scientific evidence and the quality evaluation of studies.

Educational objectives

At the end of the course students should:

- be able to identify and discuss ethical issues in life sciences and to provide argumentations in ethical decision-making,
- have acquired knowledge in biolaw and soft law.
- know the basic elements of the operating characteristics of a company, of the techniques to build a business plan and of the characteristics of innovative companies with high technological content
- know the legislation on health and safety at work in the biotechnology sector.
- know the ISO Standards on Quality Systems (ISO 9001, Standard Certification, ISO 17025 Standard Accreditation test laboratories)
- to know structured and reproducible methods for the acquisition of scientific evidence and the quality evaluation of studies.

Educational objectives

At the end of the course students should:

- be able to identify and discuss ethical issues in life sciences and to provide argumentations in ethical decision-making,
- have acquired knowledge in biolaw and soft law.
- know the basic elements of the operating characteristics of a company, of the techniques to build a business plan and of the characteristics of innovative companies with high technological content
- know the legislation on health and safety at work in the biotechnology sector.
- know the ISO Standards on Quality Systems (ISO 9001, Standard Certification, ISO 17025 Standard Accreditation test laboratories)
- to know structured and reproducible methods for the acquisition of scientific evidence and the quality evaluation of studies.

Educational objectives

The aim of the Course of Biotechnology of human reproduction is to provide a specific training in the field of gametology and fertility.
In this course of study we will discuss the main aspects of the organization and regulation of the human genome, mutation, cytogenetics. The molecular aspects will be developed for monogenic and complex diseases, and basic information about the instability of the human genome. Human genetics and its practical applications will also be described (genetic counseling, prenatal diagnosis, genetic screening). It will also address the question concerning the causes of mutations as responsible for hereditary diseases.

Provide the basis for the analysis of the molecular mechanisms underlying genetic diseases, pathophysiological and molecular mechanisms leading to the onset of the diseases. Integrate the programs of the other courses and modules that refer to the scientific-disciplinary sector General Pathology (MED / 04). Acquire the ability to connect the molecular alterations with the pathogenesis of diseases at higher integration levels (cells, tissues, organs, body). Provide the conceptual basis for the design of personalized and gene therapy approaches.

Educational objectives

The aim of the Course of Biotechnology of human reproduction is to provide a specific training in the field of gametology and fertility.
In this course of study we will discuss the main aspects of the organization and regulation of the human genome, mutation, cytogenetics. The molecular aspects will be developed for monogenic and complex diseases, and basic information about the instability of the human genome. Human genetics and its practical applications will also be described (genetic counseling, prenatal diagnosis, genetic screening). It will also address the question concerning the causes of mutations as responsible for hereditary diseases.

Provide the basis for the analysis of the molecular mechanisms underlying genetic diseases, pathophysiological and molecular mechanisms leading to the onset of the diseases. Integrate the programs of the other courses and modules that refer to the scientific-disciplinary sector General Pathology (MED / 04). Acquire the ability to connect the molecular alterations with the pathogenesis of diseases at higher integration levels (cells, tissues, organs, body). Provide the conceptual basis for the design of personalized and gene therapy approaches.

Educational objectives

The aim of the Course of Biotechnology of human reproduction is to provide a specific training in the field of gametology and fertility.
In this course of study we will discuss the main aspects of the organization and regulation of the human genome, mutation, cytogenetics. The molecular aspects will be developed for monogenic and complex diseases, and basic information about the instability of the human genome. Human genetics and its practical applications will also be described (genetic counseling, prenatal diagnosis, genetic screening). It will also address the question concerning the causes of mutations as responsible for hereditary diseases.

Provide the basis for the analysis of the molecular mechanisms underlying genetic diseases, pathophysiological and molecular mechanisms leading to the onset of the diseases. Integrate the programs of the other courses and modules that refer to the scientific-disciplinary sector General Pathology (MED / 04). Acquire the ability to connect the molecular alterations with the pathogenesis of diseases at higher integration levels (cells, tissues, organs, body). Provide the conceptual basis for the design of personalized and gene therapy approaches.

Educational objectives

The aim of the Course of Biotechnology of human reproduction is to provide a specific training in the field of gametology and fertility.
In this course of study we will discuss the main aspects of the organization and regulation of the human genome, mutation, cytogenetics. The molecular aspects will be developed for monogenic and complex diseases, and basic information about the instability of the human genome. Human genetics and its practical applications will also be described (genetic counseling, prenatal diagnosis, genetic screening). It will also address the question concerning the causes of mutations as responsible for hereditary diseases.

Provide the basis for the analysis of the molecular mechanisms underlying genetic diseases, pathophysiological and molecular mechanisms leading to the onset of the diseases. Integrate the programs of the other courses and modules that refer to the scientific-disciplinary sector General Pathology (MED / 04). Acquire the ability to connect the molecular alterations with the pathogenesis of diseases at higher integration levels (cells, tissues, organs, body). Provide the conceptual basis for the design of personalized and gene therapy approaches.

Educational objectives

To understand the principles of pharmacokinetics, their relevance in drug research and development, and importance in patient care.
To learn the main post-marketing drug monitoring activities.

Educational objectives

To understand the principles of pharmacokinetics, their relevance in drug research and development, and importance in patient care.
To learn the main post-marketing drug monitoring activities.

Educational objectives

To understand the principles of pharmacokinetics, their relevance in drug research and development, and importance in patient care.
To learn the main post-marketing drug monitoring activities.

Educational objectives

Laboratory and molecular diagnostics
Providing the foundation of knowledge of the general principles and techniques most commonly used in molecular diagnosis of human diseases.
Learning the principles and purposes of laboratory and molecular diagnostics in biotechnology applied to medical diagnostics. Understanding of the potential and limitations of the biomolecular approach, both qualitative and quantitative. Understanding of the purpose, potential, and limitations of high-throughput automated approaches. Practical application to specific genetic diseases.

Molecular diagnostics and imaging
Acquisition of the methodologies to choose the best and safest molecular diagnostic techniques for tissue application for the purpose of personalized cancer treatments.
The field of interest of “Pathology”
Distinction between “clinical” and “pathological diagnosis”
Awareness of the techniques commonly used for a histological diagnosis
Learning of basic notions on radioisotopes, radiopharmaceuticals and instrumentation for in vivo molecular imaging with radiolabelled or fluorescent probes.

Educational objectives

Laboratory and molecular diagnostics
Providing the foundation of knowledge of the general principles and techniques most commonly used in molecular diagnosis of human diseases.
Learning the principles and purposes of laboratory and molecular diagnostics in biotechnology applied to medical diagnostics. Understanding of the potential and limitations of the biomolecular approach, both qualitative and quantitative. Understanding of the purpose, potential, and limitations of high-throughput automated approaches. Practical application to specific genetic diseases.

Molecular diagnostics and imaging
Acquisition of the methodologies to choose the best and safest molecular diagnostic techniques for tissue application for the purpose of personalized cancer treatments.
The field of interest of “Pathology”
Distinction between “clinical” and “pathological diagnosis”
Awareness of the techniques commonly used for a histological diagnosis
Learning of basic notions on radioisotopes, radiopharmaceuticals and instrumentation for in vivo molecular imaging with radiolabelled or fluorescent probes.

Educational objectives

Laboratory and molecular diagnostics
To provide the basis of knowledge a) of the general principles and of the most commonly used techniques in the molecular diagnosis of human pathologies and b) of the role of the Human Papilloma Virus in the human pathology.
Leaning of principles and aims of laboratory and molecular diagnostics in the biotechnologies applied to medical diagnostics. Comprehension of potential and limits of the biomolecular approach, both qualitative and quantitative. Comprehension of aims, potential and limits of the high-throughput automated approaches. Practical application to specific genetic diseases.

Laboratory and molecular diagnostics
Providing the foundation of knowledge of the general principles and techniques most commonly used in molecular diagnosis of human diseases.
Learning the principles and purposes of laboratory and molecular diagnostics in biotechnology applied to medical diagnostics. Understanding of the potential and limitations of the biomolecular approach, both qualitative and quantitative. Understanding of the purpose, potential, and limitations of high-throughput automated approaches. Practical application to specific genetic diseases.

Molecular diagnostics and imaging
Acquisition of the methodologies to choose the best and safest molecular diagnostic techniques for tissue application for the purpose of personalized cancer treatments.
The field of interest of “Pathology”
Distinction between “clinical” and “pathological diagnosis”
Awareness of the techniques commonly used for a histological diagnosis
Learning of basic notions on radioisotopes, radiopharmaceuticals and instrumentation for in vivo molecular imaging with radiolabelled or fluorescent probes.

Educational objectives

Laboratory and molecular diagnostics
To provide the basis of knowledge a) of the general principles and of the most commonly used techniques in the molecular diagnosis of human pathologies and b) of the role of the Human Papilloma Virus in the human pathology.
Leaning of principles and aims of laboratory and molecular diagnostics in the biotechnologies applied to medical diagnostics. Comprehension of potential and limits of the biomolecular approach, both qualitative and quantitative. Comprehension of aims, potential and limits of the high-throughput automated approaches. Practical application to specific genetic diseases.

Molecular diagnostics and imaging
Acquisition of the methodologies to choose the best and safest molecular diagnostic techniques for tissue application for the purpose of personalized cancer treatments.
The field of interest of “Pathology”
Distinction between “clinical” and “pathological diagnosis”
Awareness of the techniques commonly used for a histological diagnosis
Learning of basic notions on radioisotopes, radiopharmaceuticals and instrumentation for in vivo molecular imaging with radiolabelled or fluorescent probes.

Educational objectives

Laboratory and molecular diagnostics
Providing the foundation of knowledge of the general principles and techniques most commonly used in molecular diagnosis of human diseases.
Learning the principles and purposes of laboratory and molecular diagnostics in biotechnology applied to medical diagnostics. Understanding of the potential and limitations of the biomolecular approach, both qualitative and quantitative. Understanding of the purpose, potential, and limitations of high-throughput automated approaches. Practical application to specific genetic diseases.

Molecular diagnostics and imaging
Acquisition of the methodologies to choose the best and safest molecular diagnostic techniques for tissue application for the purpose of personalized cancer treatments.
The field of interest of “Pathology”
Distinction between “clinical” and “pathological diagnosis”
Awareness of the techniques commonly used for a histological diagnosis
Learning of basic notions on radioisotopes, radiopharmaceuticals and instrumentation for in vivo molecular imaging with radiolabelled or fluorescent probes.

Educational objectives

The course aims to provide knowledge of i) the molecular mechanisms controlling physiological cellular functions (e.g., cell proliferation, death, senescence, differentiation), ii) how the cell regulates these functions in response to stimuli from the tissue microenvironment, iii) how it integrates these signals in order to contribute to the tissue homeostasis, iv) the alterations found in different physio-pathological conditions. The neoplastic transformation will be used as a paradigm of deregulations involving multi-level cellular function, and the liver as example of organ for physio-pathological studies. The student, once acquired knowledge of the mechanisms that regulate cell functions, will acquire skills to propose experimental approaches for the analysis of these functions both in vitro and in vivo.
These skills will be developed through simulations of scientific problems in interactive lessons, where students will develop critical skills, will apply the acquired knowledge and will discuss collectively the possible experimental approaches for their solving.

Educational objectives

The course aims to provide knowledge of i) the molecular mechanisms controlling physiological cellular functions (e.g., cell proliferation, death, senescence, differentiation), ii) how the cell regulates these functions in response to stimuli from the tissue microenvironment, iii) how it integrates these signals in order to contribute to the tissue homeostasis, iv) the alterations found in different physio-pathological conditions. The neoplastic transformation will be used as a paradigm of deregulations involving multi-level cellular function, and the liver as example of organ for physio-pathological studies. The student, once acquired knowledge of the mechanisms that regulate cell functions, will acquire skills to propose experimental approaches for the analysis of these functions both in vitro and in vivo.
These skills will be developed through simulations of scientific problems in interactive lessons, where students will develop critical skills, will apply the acquired knowledge and will discuss collectively the possible experimental approaches for their solving.

Educational objectives

The course aims to provide knowledge of i) the molecular mechanisms controlling physiological cellular functions (e.g., cell proliferation, death, senescence, differentiation), ii) how the cell regulates these functions in response to stimuli from the tissue microenvironment, iii) how it integrates these signals in order to contribute to the tissue homeostasis, iv) the alterations found in different physio-pathological conditions. The neoplastic transformation will be used as a paradigm of deregulations involving multi-level cellular function, and the liver as example of organ for physio-pathological studies. The student, once acquired knowledge of the mechanisms that regulate cell functions, will acquire skills to propose experimental approaches for the analysis of these functions both in vitro and in vivo.
These skills will be developed through simulations of scientific problems in interactive lessons, where students will develop critical skills, will apply the acquired knowledge and will discuss collectively the possible experimental approaches for their solving.

Educational objectives

Module of Biochemistry and Structural Biology:

Learning the usage of the major protein-related methodologies aimed at the analysis of proteins’ structure.
Learning main tools of proteomics analysis and recognizing available data, with special attention to their limitations.
Being able to 1) measure the thermodynamic stability , 2) define the mechanism of folding of small proteins, 3) measure binding affinity. Describing mechanisms of intermolecular recognition. Describing mechanisms of aggregation and fibrillogenesis. Knowing the principles of de novo protein design.
Acquiring capacity of critical reading of scientific papers.

Module of Bioinformatics and proteine engineering:

Learning bioinformatics data and tools, with special attention to their limitations
Being able to correctly use bioinformatics tools, with special attention to proteomic studies
To learn the general principles of the design, production and mutagenesis of proteins
Acquiring capacity of critical reading of scientific papers.

Educational objectives

Module of Biochemistry and Structural Biology:

Learning the usage of the major protein-related methodologies aimed at the analysis of proteins’ structure.
Learning main tools of proteomics analysis and recognizing available data, with special attention to their limitations.
Being able to 1) measure the thermodynamic stability , 2) define the mechanism of folding of small proteins, 3) measure binding affinity. Describing mechanisms of intermolecular recognition. Describing mechanisms of aggregation and fibrillogenesis. Knowing the principles of de novo protein design.
Acquiring capacity of critical reading of scientific papers.

Module of Bioinformatics and proteine engineering:

Learning bioinformatics data and tools, with special attention to their limitations
Being able to correctly use bioinformatics tools, with special attention to proteomic studies
To learn the general principles of the design, production and mutagenesis of proteins
Acquiring capacity of critical reading of scientific papers.

Educational objectives

Module of Biochemistry and Structural Biology:

Learning the usage of the major protein-related methodologies aimed at the analysis of proteins’ structure.
Learning main tools of proteomics analysis and recognizing available data, with special attention to their limitations.
Being able to 1) measure the thermodynamic stability , 2) define the mechanism of folding of small proteins, 3) measure binding affinity. Describing mechanisms of intermolecular recognition. Describing mechanisms of aggregation and fibrillogenesis. Knowing the principles of de novo protein design.
Acquiring capacity of critical reading of scientific papers.

Module of Bioinformatics and proteine engineering:

Learning bioinformatics data and tools, with special attention to their limitations
Being able to correctly use bioinformatics tools, with special attention to proteomic studies
To learn the general principles of the design, production and mutagenesis of proteins
Acquiring capacity of critical reading of scientific papers.

Educational objectives

Module of Biochemistry and Structural Biology:

Learning the usage of the major protein-related methodologies aimed at the analysis of proteins’ structure.
Learning main tools of proteomics analysis and recognizing available data, with special attention to their limitations.
Being able to 1) measure the thermodynamic stability , 2) define the mechanism of folding of small proteins, 3) measure binding affinity. Describing mechanisms of intermolecular recognition. Describing mechanisms of aggregation and fibrillogenesis. Knowing the principles of de novo protein design.
Acquiring capacity of critical reading of scientific papers.

Module of Bioinformatics and proteine engineering:

Learning bioinformatics data and tools, with special attention to their limitations
Being able to correctly use bioinformatics tools, with special attention to proteomic studies
To learn the general principles of the design, production and mutagenesis of proteins
Acquiring capacity of critical reading of scientific papers.

Educational objectives

Module of Biochemistry and Structural Biology:

Learning the usage of the major protein-related methodologies aimed at the analysis of proteins’ structure.
Learning main tools of proteomics analysis and recognizing available data, with special attention to their limitations.
Being able to 1) measure the thermodynamic stability , 2) define the mechanism of folding of small proteins, 3) measure binding affinity. Describing mechanisms of intermolecular recognition. Describing mechanisms of aggregation and fibrillogenesis. Knowing the principles of de novo protein design.
Acquiring capacity of critical reading of scientific papers.

Module of Bioinformatics and proteine engineering:

Learning bioinformatics data and tools, with special attention to their limitations
Being able to correctly use bioinformatics tools, with special attention to proteomic studies
To learn the general principles of the design, production and mutagenesis of proteins
Acquiring capacity of critical reading of scientific papers.

Educational objectives

Module of Biochemistry and Structural Biology:

Learning the usage of the major protein-related methodologies aimed at the analysis of proteins’ structure.
Learning main tools of proteomics analysis and recognizing available data, with special attention to their limitations.
Being able to 1) measure the thermodynamic stability , 2) define the mechanism of folding of small proteins, 3) measure binding affinity. Describing mechanisms of intermolecular recognition. Describing mechanisms of aggregation and fibrillogenesis. Knowing the principles of de novo protein design.
Acquiring capacity of critical reading of scientific papers.

Module of Bioinformatics and proteine engineering:

Learning bioinformatics data and tools, with special attention to their limitations
Being able to correctly use bioinformatics tools, with special attention to proteomic studies
To learn the general principles of the design, production and mutagenesis of proteins
Acquiring capacity of critical reading of scientific papers.

Educational objectives

Module of Biochemistry and Structural Biology:

Learning the usage of the major protein-related methodologies aimed at the analysis of proteins’ structure.
Learning main tools of proteomics analysis and recognizing available data, with special attention to their limitations.
Being able to 1) measure the thermodynamic stability , 2) define the mechanism of folding of small proteins, 3) measure binding affinity. Describing mechanisms of intermolecular recognition. Describing mechanisms of aggregation and fibrillogenesis. Knowing the principles of de novo protein design.
Acquiring capacity of critical reading of scientific papers.

Module of Bioinformatics and proteine engineering:

Learning bioinformatics data and tools, with special attention to their limitations
Being able to correctly use bioinformatics tools, with special attention to proteomic studies
To learn the general principles of the design, production and mutagenesis of proteins
Acquiring capacity of critical reading of scientific papers.

Educational objectives

Module of Biochemistry and Structural Biology:

Learning the usage of the major protein-related methodologies aimed at the analysis of proteins’ structure.
Learning main tools of proteomics analysis and recognizing available data, with special attention to their limitations.
Being able to 1) measure the thermodynamic stability , 2) define the mechanism of folding of small proteins, 3) measure binding affinity. Describing mechanisms of intermolecular recognition. Describing mechanisms of aggregation and fibrillogenesis. Knowing the principles of de novo protein design.
Acquiring capacity of critical reading of scientific papers.

Module of Bioinformatics and proteine engineering:

Learning bioinformatics data and tools, with special attention to their limitations
Being able to correctly use bioinformatics tools, with special attention to proteomic studies
To learn the general principles of the design, production and mutagenesis of proteins
Acquiring capacity of critical reading of scientific papers.

Educational objectives

At the end of the course students should:

- be able to identify and discuss ethical issues in life sciences and to provide argumentations in ethical decision-making,
- have acquired knowledge in biolaw and soft law.
- know the basic elements of the operating characteristics of a company, of the techniques to build a business plan and of the characteristics of innovative companies with high technological content
- know the legislation on health and safety at work in the biotechnology sector.
- know the ISO Standards on Quality Systems (ISO 9001, Standard Certification, ISO 17025 Standard Accreditation test laboratories)
- to know structured and reproducible methods for the acquisition of scientific evidence and the quality evaluation of studies.

Educational objectives

At the end of the course students should:

- be able to identify and discuss ethical issues in life sciences and to provide argumentations in ethical decision-making,
- have acquired knowledge in biolaw and soft law.
- know the basic elements of the operating characteristics of a company, of the techniques to build a business plan and of the characteristics of innovative companies with high technological content
- know the legislation on health and safety at work in the biotechnology sector.
- know the ISO Standards on Quality Systems (ISO 9001, Standard Certification, ISO 17025 Standard Accreditation test laboratories)
- to know structured and reproducible methods for the acquisition of scientific evidence and the quality evaluation of studies.

Educational objectives

At the end of the course students should:

- be able to identify and discuss ethical issues in life sciences and to provide argumentations in ethical decision-making,
- have acquired knowledge in biolaw and soft law.
- know the basic elements of the operating characteristics of a company, of the techniques to build a business plan and of the characteristics of innovative companies with high technological content
- know the legislation on health and safety at work in the biotechnology sector.
- know the ISO Standards on Quality Systems (ISO 9001, Standard Certification, ISO 17025 Standard Accreditation test laboratories)
- to know structured and reproducible methods for the acquisition of scientific evidence and the quality evaluation of studies.

Educational objectives

At the end of the course students should:

- be able to identify and discuss ethical issues in life sciences and to provide argumentations in ethical decision-making,
- have acquired knowledge in biolaw and soft law.
- know the basic elements of the operating characteristics of a company, of the techniques to build a business plan and of the characteristics of innovative companies with high technological content
- know the legislation on health and safety at work in the biotechnology sector.
- know the ISO Standards on Quality Systems (ISO 9001, Standard Certification, ISO 17025 Standard Accreditation test laboratories)
- to know structured and reproducible methods for the acquisition of scientific evidence and the quality evaluation of studies.

Educational objectives

Lo studente dovrà acquisire la capacità di analizzare criticamente approcci terapeutici biotecnologici, come la messa a punto di modelli di terapie cellulari e tissutali sostitutive, a partire dalla sperimentazione in vitro, fino al modello animale e alla validazione preclinica. Dovrà conoscere e saper applicare metodologie biotecnologiche per l’allestimento di colture cellulari primarie, istotipiche, organotipiche e acquisire familiarità con la messa a punto di protocolli sperimentali con finalità traslazionale-terapeutica.

Educational objectives

Understanding and application of cellular, tissue and organ Bioengineering methods.
Understanding the possibilities of acute and subacute liver failure therapy based on the construction of engineered liver tissue.

Educational objectives

Understanding and application of cellular, tissue and or-gan Bioengineering methods.

Educational objectives

Students must acquire the ability to develop therapeutic strategies based on biotechnological bases (such as the development of cell therapies and tissue replacement models and models of devices supporting the heart function) in pre-clinical and translational field.

Educational objectives

The training objective is to give students the necessary tools to understand the possibilities of acute and subacute liver failure therapy based on the construction of engineered liver tissue.
Acquisition of know how on the mechanisms that regulate the proliferation and cell differentiation, with particular regard to the study of multipotent adult stem cells of epithelial origin. Definition of “identity” and biological “potency” for cell therapies aimed to repair damaged tissues and methods to obtain the results. Contribution of translational research, conveyed with technology transfer from innovative fields such as biotechnology, bioinformatics, nanotechnology, to transfer in to the clinic. Use of new functionalized scaffolds through the insertion of other cell types (eg. fibroblasts, endothelial cells) or growth factors, for the in vitro production of "organoids" tissues. Addressing the skills of clinical application of the cell based therapies to obtain in vitro epithelial layer and mucous to be transfer in to patients with rare diseases with a strong social impact.

Educational objectives

Acquisition of information about the clinical application of biomaterials, in particular those of metal, composites, polymeric and ceramic.
Acquire information on the biocompatibility of biomaterials and pathology.
Learning of elementaly tissue reactions associated with the use of biomaterials. Comprehension of the essential aspects of biomaterial-dependent pathology. Comprehension of the role of experimental models in the development and analysis of biomaterials
Learning the basic principles related to the materials used in medicine and in particular to biomaterials. Knowledge of the main characterization techniques and manufacturing processes of materials.
Understanding of the potential and application limits of biomaterials in medicine.

Educational objectives

Acquisition of information about the clinical application of biomaterials, in particular those of metal, composites, polymeric and ceramic.
Acquire information on the biocompatibility of biomaterials and pathology.
Learning of elementaly tissue reactions associated with the use of biomaterials. Comprehension of the essential aspects of biomaterial-dependent pathology. Comprehension of the role of experimental models in the development and analysis of biomaterials
Learning the basic principles related to the materials used in medicine and in particular to biomaterials. Knowledge of the main characterization techniques and manufacturing processes of materials.
Understanding of the potential and application limits of biomaterials in medicine.

Educational objectives

Acquisition of information about the clinical application of biomaterials, in particular those of metal, composites, polymeric and ceramic.
Acquire information on the biocompatibility of biomaterials and pathology.
Learning of elementaly tissue reactions associated with the use of biomaterials. Comprehension of the essential aspects of biomaterial-dependent pathology. Comprehension of the role of experimental models in the development and analysis of biomaterials
Learning the basic principles related to the materials used in medicine and in particular to biomaterials. Knowledge of the main characterization techniques and manufacturing processes of materials.
Understanding of the potential and application limits of biomaterials in medicine.

Educational objectives

Acquisition of information about the clinical application of biomaterials, in particular those of metal, composites, polymeric and ceramic.
Acquire information on the biocompatibility of biomaterials and pathology.
Learning of elementaly tissue reactions associated with the use of biomaterials. Comprehension of the essential aspects of biomaterial-dependent pathology. Comprehension of the role of experimental models in the development and analysis of biomaterials
Learning the basic principles related to the materials used in medicine and in particular to biomaterials. Knowledge of the main characterization techniques and manufacturing processes of materials.
Understanding of the potential and application limits of biomaterials in medicine.

Educational objectives

Knowledge of the fundamentals of continuum mechanics and of the basic equations of fluid mechanics; their application to emodynamics

Educational objectives

Knowledge of the fundamentals of continuum mechanics and of the basic equations of fluid mechanics; their application to emodynamics

Educational objectives

Knowledge of the fundamentals of continuum mechanics and of the basic equations of fluid mechanics; their application to emodynamics

Educational objectives

Knowledge of the fundamentals of continuum mechanics and of the basic equations of fluid mechanics; their application to emodynamics

Educational objectives

Knowledge of the fundamentals of continuum mechanics and of the basic equations of fluid mechanics; their application to emodynamics