Nursing REPLICA F-ASL ROMA 4 - CIVITAVECCHIA

Microbiology: The microbial world. The microbial cell. Microorganisms and their natural environments. The impact of microorganisms on humans. General characteristics of infectious agents. Prions. Viruses: classification; structure; replication; viral genetics. Bacteria: classification; structure; replication; nutrition and growth, growth factors; physical and environmental conditions affecting bacterial growth; growth curve; bacterial spores. Fungi: classification; structure; replication. Hints of Parasitology. Protozoa: classification, structure, replication. Relationship of infectious agents to humans. Definitions; Microbiota and Microbiome; role of microbiota in human health; dysbiosis and disease. Pathogen transmission, colonization, invasiveness, disease. Microbial biofilms. Virulence factors. Exotoxins. Endotoxins. Mycotoxins. Intoxication and toxins. Mechanisms of evasion from antimicrobial defenses. Antigenic variability of microorganisms. Microbiological diagnostics. Methods of collection and transport of biological specimens; direct diagnosis; culture examination; microscopic examination; biochemical techniques; molecular techniques. Indirect diagnosis. Antimicrobial and antiviral drugs. Definitions; main mechanisms of action. mechanisms of resistance. Prebiotics and probiotics. Efficacy testing of antimicrobial drugs: diffusion and dilution methods, antibiogram, MIC. Vaccines and serums Definitions; Characteristics of vaccines; types of vaccines. serums. Sterilization and disinfection and storage. Definitions. Antiseptic disinfectants and preservatives and factors affecting their activity. Sterilization. Main methods of sterilization. Deterioration and preservation of pharmaceuticals. Biological and occupational hazards. Resident Population and Disease-Causing Microorganisms in the Following Systems: Respiratory Tract, Genitourinary System, Gastrointestinal Tract, Skin, and Skin Appendages.

Principi di Microbiologia Clinica per le scienze infermieristiche. Piccin Microbiologia Clinica, V ed. CEA Microbiologia e Microbiologia Clinica, II ed. Pearson.