Environment and Workplace Prevention Techniques

THE MOLECULAR DESIGN OF LIFE Chemical properties of water. Chemical bonds, functional groups and key organic molecules in biochemistry PROTEINS - Amino acids: classification, isomerism, zwitterions, standard and non-standard aminoacids, peptide bond formation. Proteins: Functions, primary structure, secondary structure (alpha helix and beta sheet, collagen), tertiary structure, denaturation and denaturing agents, quaternary structure. Myoglobin and hemoglobin: transport and storage of oxygen, heme and protein structure, functional aspects, oxygen dissociation curves for myoglobin and hemoglobin, allosteric properties of hemoglobins, action of carbon monoxide. Heme catabolism and bilirubin formation. Biomedical importance and implications. Enzymes: classification by reaction type and mechanism, prosthetic groups, cofactors and coenzymes, catalysis, transition state, activation energy, the kinetics of enzymatic catalysis, Competetive and noncompetetive inhibition. Plasma proteins and enzymes of clinical interest. Protein turnover and amino acid catabolism . CARBOHYDRATES - classification, monosaccharides, disaccharides and polysaccharides. Glucose: metabolism and regulation: glycolysis and the oxidation of pyruvate,,the citric acid cycle, oxidative phosphorylation, pentose phosphate pathway, glycogen and glycogen metabolism. Regulation of blood glucose: insulin and glucagon LIPIDS - classification, saturated and unsaturated fatty acids, triglycerides, phospholipids, steroids. Fatty acids metabolism, plasma lipids of clinical interest. Lipoprotein: formation and metabolism. OVERVIEW OF METABOLISM Basic concepts and design: anabolism and catabolism. Pathways that process the major products of digestion, the flux of metabolites in metabolic pathways. Regulation strategies. VITAMINES - classification and biomedical importance. Lipid-soluble vitamins (A, E, D, K) and water-soluble vitamins (B group, C). HORMONES - classification, hormone receptors and signal transduction mechanisms.

General chemistry and preparatory biochemistry knowledge

Chimica e Biochimica per le lauree triennali dell'area biomedica, M. Samaja, R.Paroni- Piccin Le basi della biochimica, D.R. Ferrier - Zanichelli Conoscere la Biochimica, Terry Brown - Zanichelli Chimica,Biochimica e Biologia Applicata, M. Stefani - Zanichelli Appunti di biochimica per le lauree triennali- M.V. Catani - Piccin

the exam will focus on an oral interview on the topics listed in the program

mandatory

The exam includes a single oral test relating to the 3 teaching modules of the integrated course. It has the objective of ascertaining: a) the degree of knowledge and understanding; b) the ability to apply the acquired skills; c) the quality of the presentation (clarity, coherence, scientific rigor, completeness, synthesis capacity). it will last about 45 min and includes a variable number of questions relating to the topics of the integrated course.

the exam will focus on an oral interview on the topics listed in the program