Nursing REPLICA CELIO

Introduction to immunology. Organs and tissues of the immune system. The cellular and molecular components of the immune system. Innate immunity: anatomical and physiological barriers; phagocytosis, professional phagocytes and their receptors; the complement system; cytokines; natural killer (NK) cells. Macrophages M1 and M2. Specific immunity: characteristics and functions. B lymphocytes and their antigen receptor: characteristics of B lymphocytes; secreted antibodies: structure, functions, classification. T lymphocytes: characteristics of helper (CD4 +) and cytotoxic (CD8 +) T lymphocytes. MHC molecules and their role. The cells that present the antigen and their role. The generation of the receptor repertoire and clonal selection. Tolerance: recognition and distinction between self and non-self; self tolerance. The immune response against pathogens. Vaccines, vaccination strategies, types of vaccines. Immunopathology: the alterations of the immune response; classification of immunopathologies; type I hypersensitivity: allergies; hypersensitivity of type II, III and IV; disruption of tolerance and autoimmunity; congenital and acquired immunodeficiencies. Transplant immunology: classification of transplants; types of transplant rejection; GVHD.

In order to understand the teaching content and to achieve the learning objectives, at the beginning of the didactic activities foreseen by the didactic module the student must possess basic knowledge of hystology and anatomy.

j.R. Regueiro Gonzalez-C.Lopez Larrea Immunologia: biologia e patologia del sistema immunitario Casa editrice Piccin The slides presented in class will also be provided.

The teacher delivers the lectures with traditional methods, with audiovisual aids and with scheduling of the lessons as reported on the GOMP and published on the CdS website. The e-learning platform will be used as a teaching support

The student is required to attend educational activities, formal, non-formal, vocational. The frequency is checked by the teachers through signature / updated lists provided by the Academic Office, as established by CCL. The certificate of mandatory attendance to the teaching course is required to the student to be admitted at the final test.

At the end of the course, the student should be able to demonstrate: to know the fundamentals of immune responses , as well as of the defense mechanisms against infections, the main alterations of these mechanisms and the related consequences as well. To pass the exam the student needs to achieve a grade of not less than 18/30.

The teacher delivers lectures with traditional methods (face-to-face), with power point presentation and audiovisual aids, scheduling of lessons as reported on GOMP Aure/Orari system, published on the website of CdS. The e-learning platform will be used as a teaching support The slides presented in class will also be provided.