Biomedical Engineering

1. Anatomy and physiology of the urinary system 2. Renal diseases and acute and chronic renal failure 3. Conservative and replacement therapy of renal disease 4. Dialysis techniques and possible application incidents 5. Organ preservation techniques: cold storage and perfusion machine 6. Anatomy and physiology of the liver 7. Hepatic diseases and acute and chronic liver failure 8. Conservative therapy and support devices 9. MARS (Molecular Adsorbent Recirculating System) 10. Liver transplant 11. Treatment of sepsis with devices 12. Anatomy and physiology of the pancreas 13. Diabetes mellitus 14. Devices for the control and treatment of diabetes 15. Pancreas transplant 16. Anatomy and physiology of the respiratory system 17. Respiratory failure 18. Device for the treatment of respiratory failure respiratory 19. Lung transplant 20. Application of wearable technologies in various areas of the medical sector. In-depth analysis of Extended Reality technology, its potential and its limitations. Creation of a Mixed Reality experience on the Unity Engine platform (C# language) for a holographic viewer capable of real-time representation of data acquired from a sensorised bracelet for monitoring vital parameters. o State of the art in the use of wearable and extended reality technologies in healthcare o Operation of the MAXREFDES104 sensorised bracelet for the acquisition of vital signs (ECG, PPG and temperature) and acquisition in the classroom of data from a subject to be used for the implementation of the project o Introduction to the use of the Unity platform (steps for installing the software and drivers required for mixed reality, starting a project, basic features for project implementation) and the properties of 3D models (mesh and texture). Classroom exercise. o Introduction to the C# language (Visual Studio platform, language properties), examples of simple C# code and classroom development of the code needed for the project (code for reading and graphically representing the vital signs acquired). Classroom exercise. o Completion of the final Unity project in the classroom, consisting of a mixed reality scene that graphically displays the vital signs previously acquired by the sensorised bracelet at an appropriate frequency in a holographic visualisation (determining the frequency of data representation based on the sampling frequency and the computational capacity of the computer, determining the need for any data processing prior to representation). o Discussion on the limitations and potential of the technology presented and the project implemented in relation to its application in a clinical context.

Notions of normal human anatomy and physiology, biochemistry and physics. Knowledge of computer science (ability to understand a code), signal processing (sampling frequency, Nyquist frequency) and biomedical signals (ECG and PPG).

- Fisiologia medica. Guyton e Hall. Edizioni Edra 2021. - Handbook of Dialysis. Daurgirdas M.D, Blake P. Fifth Edition. Lippincott Williams & Wilkins 2014. - Hepatology: A clinical textbook. Mauss - Berg - Rockstroh - Sarrazin – Wedemeyer. Flying Publisher 2008. - Trapianti di organi e tessuti. Venuta F. Rossi M. Editore SEU 2009. - Kidney transplantation: Principles and practice. Peter Morris, Stuart J. Knechtle - Elsevier Health Sciences, 30 giu 2008. Teaching material provided by the teacher, slides, bibliographic references for articles: summary of the steps for the creation of the Unity project (software installation, C# code and creation of a holographic scene on Unity). Technical data sheet of the sensorized bracelet. References cited. Useful links to online manuals and guides for using the software

Regular attendance is strongly recommended.

Oral interview and project presentation

group exercises and frontal lessons