NANOBIOTECHNOLOGY

Course objectives

Aim of this course is getting to know the technologies to produce biocompatible nanomentric particles by using highly sustainable and maximally green processes which mainly resort to using naturally-sourced biological matrices. The student will learn: 1. The main classes of biological substances, 2. The methodologies for obtaining these substances from natural biomass, 3. the methodologies for producing functional nanoparticulate from each of these classes of substances, 5. The main processes and equipment that implement these production processes. The student will also learn the main problems of biomedical and cosmetic use of nanotechnologies. The student who will exhibit a regular attendance of the course will be able to participate in group work intended to develop and strengthen soft skills such as: the ability to work in a group, the ability to dialogue with colleagues from different backgrounds,the ability to write a scientific/technical report and the ability to present one's work.

Channel 1
MARCO BRAVI Lecturers' profile

Program - Frequency - Exams

Course program
Biological substances and microorganisms as biocatalysts and raw materials feedstock for the formation of nanoparticles (fundamentals, biological fractions of nanotechnology relevance, production of biological fractions of nanotechnology relevance). Nucleation and crystallisation of proteins (fundamentals, characterisation, process screening and identification, production). Formation and use of nanoparticles by biotechnological techniques (microorganisms, culture media, extracts, switchable solvents). Applications of nanoparticles in the bio-related fields (food, pharma, cosmetic, agriculture).
Prerequisites
General and organic chemistry
Books
ALL information relating to the teaching activity of prof. Marco Bravi (lesson times and any exceptions; methods of conducting lessons and tools used; student reception hours; exams; available project works), updated in real time, can be found by consulting the URL: https://sites.google.com/site/marcobravi/ Study materials (generally scientific review articles) will be shared to the attending students during the semester the course is being taught. Students will receive a Google Drive share by being included in the Google Classroom of the course itself. Topic 1: Course introductory material (slide nbt-lecture-0.1-course_introductory_material) Topic 2: Basics of biological entities spencer2xxxsnk.pdf jurtshuk1996bme.pdf xxxxx2xxxntp.pdf Topic 3: Relevant biologic substances ranaudo2006ccp.pdf divya2018cnp.pdf alcazaralay2015ppm.pdf gupta2019uoc.pdf rehman2019ppw.pdf hekmat2015lsc.pdf huang2019scl baiwa2019crc Topic 4: Biotechnology galanakis2018srr-sustainable_recovery_reutilization_cereal_processing_products.pdf cruzsolis2023aei.pdf ikegwu2022pot.pdf tamayotenorio2018udp.pdf xu2014pmb.pdf kumar2018tan.pdf abranches2022tvd.pdf jessop2012cts.pdf cicci2018cei.pdf Topic 5: Naturally Occurring Nanostructures in food axelos2017naf-nanotechnology_agriculture_food_science.pdf lima2015mns.pdf Topic 6: Production of lipid and surfactant based nanostructures axelos2017naf-nanotechnology_agriculture_food_science.pdf tadros2009est-emulsion_science_technology.pdf salvi2019nlc.pdf khorasani2018ntf.pdf boxall2012dss.pdf chafidz2018ffp.pdf patil2019sln.pdf Topic 7: Production of poly-saccharide based nanostructures axelos2017naf-nanotechnology_agriculture_food_science.pdf kang2015cnb.pdf divya2018cnp.pdf quinones2018cbs.pdf george2015cns.pdf Topic 8: Production of protein based nanostructures axelos2017naf-nanotechnology_agriculture_food_science.pdf davidovpardo2015fgp.pdf diaz2018bsp.pdf tarhini2017pbn.pdf Topic 9: Microbial production of inorganic nanoparticles rai2011mnm-metal_nanoparticles_microbiology.pdf pathak2019rdg.pdf pasula2017ens.pdf li2011bnm.pdf Topic 10: Biological production of inorganic nanoparticles rai2011mnm-metal_nanoparticles_microbiology.pdf pathak2019rdg.pdf pasula2017ens.pdf li2011bnm.pdf Topic 11: Switchable solvents-mediated nanoparticle production joye2013pna.pdf ethier2014ris.pdf su2017pal.pdf Topic 12: Protein crystallisation processes myerson2002hic-handbook_industrial_crystallization.pdf hekmat2015lsc.pdf
Teaching mode
Teaching will only be carried out in presence in the assigned classroom. All lectures will be taught in English.
Frequency
Attendance is facultative. However, only regularly attending students will have their "small groupwork projects" evaluated for the final mark (together with the compulsory written test).
Exam mode
The written exam includes 10 multiple choice questions, plus an open-ended question (to be provided by the student). The oral exam is optional. If it is not carried out, it will be counted as passed with the vote of 18/30. The final mark will be assigned as the average of the marks obtained in the two tests. Only those admitted to the "evaluated groupwork" can replace the oral test with the presentation of their groupwork.
Lesson mode
Teaching will only be carried out in presence in the assigned classroom. All lectures will be taught in English.
MARCO BRAVI Lecturers' profile

Program - Frequency - Exams

Course program
Biological substances and microorganisms as biocatalysts and raw materials feedstock for the formation of nanoparticles (fundamentals, biological fractions of nanotechnology relevance, production of biological fractions of nanotechnology relevance). Nucleation and crystallisation of proteins (fundamentals, characterisation, process screening and identification, production). Formation and use of nanoparticles by biotechnological techniques (microorganisms, culture media, extracts, switchable solvents). Applications of nanoparticles in the bio-related fields (food, pharma, cosmetic, agriculture).
Prerequisites
General and organic chemistry
Books
ALL information relating to the teaching activity of prof. Marco Bravi (lesson times and any exceptions; methods of conducting lessons and tools used; student reception hours; exams; available project works), updated in real time, can be found by consulting the URL: https://sites.google.com/site/marcobravi/ Study materials (generally scientific review articles) will be shared to the attending students during the semester the course is being taught. Students will receive a Google Drive share by being included in the Google Classroom of the course itself. Topic 1: Course introductory material (slide nbt-lecture-0.1-course_introductory_material) Topic 2: Basics of biological entities spencer2xxxsnk.pdf jurtshuk1996bme.pdf xxxxx2xxxntp.pdf Topic 3: Relevant biologic substances ranaudo2006ccp.pdf divya2018cnp.pdf alcazaralay2015ppm.pdf gupta2019uoc.pdf rehman2019ppw.pdf hekmat2015lsc.pdf huang2019scl baiwa2019crc Topic 4: Biotechnology galanakis2018srr-sustainable_recovery_reutilization_cereal_processing_products.pdf cruzsolis2023aei.pdf ikegwu2022pot.pdf tamayotenorio2018udp.pdf xu2014pmb.pdf kumar2018tan.pdf abranches2022tvd.pdf jessop2012cts.pdf cicci2018cei.pdf Topic 5: Naturally Occurring Nanostructures in food axelos2017naf-nanotechnology_agriculture_food_science.pdf lima2015mns.pdf Topic 6: Production of lipid and surfactant based nanostructures axelos2017naf-nanotechnology_agriculture_food_science.pdf tadros2009est-emulsion_science_technology.pdf salvi2019nlc.pdf khorasani2018ntf.pdf boxall2012dss.pdf chafidz2018ffp.pdf patil2019sln.pdf Topic 7: Production of poly-saccharide based nanostructures axelos2017naf-nanotechnology_agriculture_food_science.pdf kang2015cnb.pdf divya2018cnp.pdf quinones2018cbs.pdf george2015cns.pdf Topic 8: Production of protein based nanostructures axelos2017naf-nanotechnology_agriculture_food_science.pdf davidovpardo2015fgp.pdf diaz2018bsp.pdf tarhini2017pbn.pdf Topic 9: Microbial production of inorganic nanoparticles rai2011mnm-metal_nanoparticles_microbiology.pdf pathak2019rdg.pdf pasula2017ens.pdf li2011bnm.pdf Topic 10: Biological production of inorganic nanoparticles rai2011mnm-metal_nanoparticles_microbiology.pdf pathak2019rdg.pdf pasula2017ens.pdf li2011bnm.pdf Topic 11: Switchable solvents-mediated nanoparticle production joye2013pna.pdf ethier2014ris.pdf su2017pal.pdf Topic 12: Protein crystallisation processes myerson2002hic-handbook_industrial_crystallization.pdf hekmat2015lsc.pdf
Teaching mode
Teaching will only be carried out in presence in the assigned classroom. All lectures will be taught in English.
Frequency
Attendance is facultative. However, only regularly attending students will have their "small groupwork projects" evaluated for the final mark (together with the compulsory written test).
Exam mode
The written exam includes 10 multiple choice questions, plus an open-ended question (to be provided by the student). The oral exam is optional. If it is not carried out, it will be counted as passed with the vote of 18/30. The final mark will be assigned as the average of the marks obtained in the two tests. Only those admitted to the "evaluated groupwork" can replace the oral test with the presentation of their groupwork.
Lesson mode
Teaching will only be carried out in presence in the assigned classroom. All lectures will be taught in English.
  • Lesson code10592628
  • Academic year2025/2026
  • CourseChemical Engineering
  • CurriculumChemical Engineering for innovative processes and products - in lingua inglese
  • Year2nd year
  • Semester1st semester
  • SSDING-IND/25
  • CFU6