Course program
Basic principles
Fundamental interactions between electromagnetic fields and biological systems.
Multiphysics models of the human body.
Methods and tools for the solution of the electromagnetic problem in the human body
Electrochemotherapy
Mechanism of electroporation induction
Standard protocol, device and its fundamental components
The role of Electric field and treatment planning
Cancer pathologies treated
LAB: computational dosimetry for treatment planning
LAB: experience with members of a leading Italian company in the field
Transcranial Magnetic Stimulation
Basic principles
Protocols, devices and coil
Major pathologies treated: depression, stroke, neurodegenerative,
Calculation of Electric field distribution
Neuronavigation
LAB: E field induction by a coil on a simplified head model
LAB: dosimetry of a figure-8 on the brain of virtual human body
Transcranial Direct Current Stimulation
Operating Principles
Pathologies involved
The device and its fundamental components
Computational modeling and dose determination
Safety issues
LAB: computationl dosimetry of an electrode mountage the brain of virtual human body
Prerequisites
Basic knowledge of electromagnetic fields
Books
Selected Chapters from:
1. Handbook of Electroporation, Damijan Miklavcic, Springer
2. Transcranial Magnetic Stimulation, Alexander Rotenberg, Jared Cooney Horvath, Alvaro Pascual-Leone, Humana Press
3. Practical Guide to Transcranial Direct Current Stimulation, Principles, Procedures and Applications, Helena Knotkova, Michael A. Nitsche, Marom Bikson, Adam J. Woods, Springer
Selection of Papers available on the course moodle site
Frequency
Not Mandatory but recommended in particular for the exercises
Exam mode
TWO PARTS contributing equally to the final mark:
1) LOGBOOK of the LAB experiences
2) Two oral questions taken from the whole programme
Overall, the exam test aims to assess the level that the student has achieved in acquiring the skills described in the training objectives, with particular reference to:
a) understanding of the concepts transmitted during the lessons, not only from the theoretical point of view but also in reference to applicative problems;
b) ability to learn and organize concepts;
d) accuracy and precision in exposure.
Lesson mode
Teaching will be carried out by addressing the 4 main topics,
as far as possible each topic covered in theory will be followed by a practical or simulative laboratory exercise.
Students will be provided with the opportunity to install on their Computers a temporary license of Comsol Multiphysics Classkit,
useful for the exercises.
Various digital technologies for teaching will be integrated as far as possible