Medicine and Surgery

General Objectives The course in Biochemistry and Molecular Biology has two main objectives: 1. to provide to the students the key knowledge to understand the physical, chemical and biological frameworks in which biochemical reactions take place and to explain how these reactions determine physiological or pathological state. The comprehension of the mechanisms of integration and regulation of metabolic pathways is crucial to this aim. 2. To educate the students to the comprehension of the principles and the methodologies applied to realize a Personalized Medicine approach. To meet this target, particular attention is paid to stimulate the interest and the critical approach of the student, by developing the various topics in a logical and consequential manner, highlighting the varied interplay between different biochemical themes and the strategies employed in the “patient-centred” medical strategies. Specific Objectives Knowledge and understanding: At the end of the course, the student must have understood: the structure-function relationsohips of the main biological molecules; the essential biochemical mechanisms underlying a fully functional metabolism; the essential methods and technologies used in biochemistry and molecular biology; the basic principles and methodology applied to realize a Personalized Medicine approach. Ability to apply knowledge and understanding: at the end of the course, the student will acquire the ability to apply the mechanisms of integration and regulation of metabolic pathways, to the molecular causes underlying the pathological processes. The student will have the comprehension of the principles and the methodologies applied to realize a Personalized and precision Medicine approach. Autonomy of judgment: particular attention is paid to stimulate the interest and the critical approach of the student, by developing the various topics in a logical and consequential manner, highlighting the varied interplay between different biochemical themes and the strategies employed in the “patient-centred” medical strategies. Communication skills: the student will acquire the ability to effectively use the communication tools of publications and scientific communications. Learning skills: the student will acquire the transversal learning capacity common to the logic of scientific investigation in the biomedical field.