Industrial Chemistry

A good knowledge of organic chemistry and biochemistry.

Dewick “Chimica, biosintesi e bioattività delle sostanze naturali” PICCIN Giovanni Greco – Farmacocinetica e Farmacodinamica su Basi Chimico-Fisiche, Edizioni Loghia Goodman & Gilman’s – The Pharmacological Basis of Therapeutics, McGraw Hill Lecture notes and handouts available during the course

optional, recommended

The oral exam will allow to evaluate how knowledge and understanding of the main classes of bioactive natural products and of pharmacologically active compounds have been developed; how the fundamentals of metabolic pathways leading to natural products and of structure activity relationships have been understood. The oral exam will also allow to evaluate if reasoning and critical thinking in the field of modern synthetic methodologies applied to natural products have been developed, and if communication skills fit the educational level of Laurea Magistrale.

The course is articulated in 48 h of lectures. Class will be based on slides illustrating the contents of each lesson. A copy of the slides is available at the beginning of the course, together with the detailed programme. Lessons follow a weekly articulation which is approved in advance by the Industrial Chemistry "Consiglio di Area Didattica" (CAD).

II module: Pharmacologically active substances. The path from "active ingredient" to "drug." Methods for identifying active ingredients. Pharmacodynamics and pharmacokinetics. Structure-activity relationships. Overview of cellular physiology. Mechanisms of action of anti-infective, anti-inflammatory (corticosteroids and NSAIDs), and anticholinesterase drugs.

A good understanding of organic chemistry and biochemistry.

Dewick "Chimica, biosintesi e bioattività delle sostanze naturali" PICCIN Giovanni Greco - Farmacocinetica e Farmacodinamica su Basi Chimico-Fisiche, Edizioni Loghia Goodman & Gilman's - The Pharmacological Basis of Therapeutics, McGraw Hill Lecture notes and handouts available during the course.

Optional, recommended.

The orai exam will allow to evaluate how knowledge and understandmg of the main classes of bioactive naturai Products and of pharmacologically active compounds have been developed, how the fundamentals of metabolic pathways leading to naturai products and of structure activity relatronships have been understood. The orai exam will also allow to evaluate if reasoning and criticai thinking in the field of modern synthetic methodologies applied to naturai products have been developed, and if communication skills fit the educational level of Laurea Magistrale.

The course is articulated in 48 h of lectures. Class will be based on slides illustrating the contents of each lesson. A copy of the slides is available at the beginning of the course, together with the detailed programme. Lessons follow a weekly articulation which is approved in advance by the Industriai Chemistry "Consiglio di Area Didattica" (CAD).