LUCIANO SASO

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Prof. Luciano Saso’s CV
(as of September 2025)

PERSONAL INFORMATION Date of birth: 10-2-1964
Nationality: Italian
E-mail:luciano.Saso@uniroma1.it

CURRENT POSITION Full professor of Pharmacology at Sapienza University of Rome, Italy
(www.uniroma1.it)
Highly Cited Researcher 2022 and 2024 (https://clarivate.com/highly-cited-researchers/)

SCIENTIFIC PROFILE H-index (Google Scholar) 77
No. publications (Pubmed) 445
No. citations (Google Scholar) >25,000
EDUCATION PhD in Pharmaceutical Sciences from Sapienza University of Rome (1992)
RESEARCH AREAS AND SCIENTIFIC INTERESTS https://www.researchgate.net/profile/Luciano-Saso
https://scholar.google.com/citations?user=W7-l9IsAAAAJ&hl=en
https://orcid.org/0000-0003-4530-8706 https://loop.frontiersin.org/people/613175/overview

 
Scientific Articles (last 5 years, PubMed)

Year N° articles
(PubMed)
2025 22
2024 38
2023 40
2022 54
2021 53
2020 30

1: Matlin SA, Claron IMM, Merone J, Netto G, Takian A, Zaman MH, Saso L.
Artificial Intelligence in migrant health: a critical perspective on
opportunities and risks. Lancet Reg Health Eur. 2025 Aug 8;57:101421. doi:
10.1016/j.lanepe.2025.101421. PMID: 40823188; PMCID: PMC12356465.

2: Perendija S, Dimić D, Eichhorn T, Rakić A, Saso L, Nakarada Đ, Đikić D,
Dragojević T, Dimitrić Marković J, Kaluđerović GN. Synthesis, Characterization,
HSA/DNA Binding, and Cytotoxic Activity of
[RuCl₂(η⁶-p-cymene)(bph-κN)] Complex.
Molecules. 2025 Jul 23;30(15):3088. doi: 10.3390/molecules30153088. PMID:
40807263; PMCID: PMC12348660.

3: Saha S, Capozzi A, Profumo E, Alessandri C, Sorice M, Saso L, Buttari B.
Lupeol Attenuates Oxysterol-Induced Dendritic Cell Activation Through
NRF2-Mediated Antioxidant and Anti-Inflammatory Effects. Int J Mol Sci. 2025 Jul
25;26(15):7179. doi: 10.3390/ijms26157179. PMID: 40806311; PMCID: PMC12346829.

4: Maftei D, Di Certo MG, Maurizi R, Veltri F, Rosina M, Bissacco J, Mascioli D,
Bovenzi R, Simonetta C, Mancini M, Buttarazzi V, Viola S, Gravina A, Maglie MG,
Rinaldi AM, Gabanella F, Saso L, Stefani A, Passali FM, Di Girolamo S,
Pierantozzi M, Valle C, Ferri A, Mercuri NB, Lattanzi R, Severini C, Schirinzi
T. α-Synuclein-Related Mitochondria-Nrf2 Dysfunction in Parkinson's Disease
Olfactory Mucosa. Ann Neurol. 2025 Jun 12. doi: 10.1002/ana.27292. Epub ahead of
print. PMID: 40503742.

5: Temaj G, Saha S, Chichiarelli S, Telkoparan-Akillilar P, Nuhii N,
Hadziselimovic R, Saso L. Polyploid giant cancer cells: Underlying mechanisms,
signaling pathways, and therapeutic strategies. Crit Rev Oncol Hematol. 2025
Sep;213:104802. doi: 10.1016/j.critrevonc.2025.104802. Epub 2025 Jun 6. PMID:
40484156.

6: Simeonova L, Leseva M, Stoyanov K, Mai A, Saso L, Dimitrova P. Neutrophils
shape the therapeutic efficacy of sirtuin 1 activity modulators in murine
influenza virus infection. Biochim Biophys Acta Mol Basis Dis. 2025
Oct;1871(7):167915. doi: 10.1016/j.bbadis.2025.167915. Epub 2025 May 24. PMID:
40419167.

7: Davinelli S, Medoro A, Siracusano M, Savino R, Saso L, Scapagnini G, Mazzone
L. Oxidative stress response and NRF2 signaling pathway in autism spectrum
disorder. Redox Biol. 2025 Jun;83:103661. doi: 10.1016/j.redox.2025.103661. Epub
2025 May 2. PMID: 40324316; PMCID: PMC12099462.

8: Ardekani OS, Letafati A, Dehkordi SE, Farahani AV, Bahari M, Mahdavi B,
Ariamand N, Taghvaei M, Kohkalani M, Pirkooh AA, Jazayeri SM, Saso L. From
infection to infertility: a review of the role of human papillomavirus-induced
oxidative stress on reproductive health and infertility. Eur J Med Res. 2025 Apr
28;30(1):339. doi: 10.1186/s40001-025-02605-4. PMID: 40296084; PMCID:
PMC12036311.

9: Telkoparan-Akillilar P, Chichiarelli S, Tucci P, Saso L. Integration of
MicroRNAs with nanomedicine: tumor targeting and therapeutic approaches. Front
Cell Dev Biol. 2025 Apr 7;13:1569101. doi: 10.3389/fcell.2025.1569101. PMID:
40260417; PMCID: PMC12009947.

10: De Battistis F, Djordjevic AB, Saso L, Mantovani A. Constitutive androstane
receptor, liver pathophysiology and chemical contaminants: current evidence and
perspectives. Front Endocrinol (Lausanne). 2025 Apr 4;16:1472563. doi:
10.3389/fendo.2025.1472563. PMID: 40255499; PMCID: PMC12005993.

11: Miceli V, Lo Gerfo E, Russelli G, Bulati M, Iannolo G, Tinnirello R, Cimino
M, Saso L, Avorio F, Lo Re V. Circulating Biomarkers to Predict Post-Operative
Cognitive Decline in Patients Undergoing Coronary Artery Bypass Grafting. Cell
Mol Neurobiol. 2025 Apr 21;45(1):37. doi: 10.1007/s10571-025-01553-1. PMID:
40254644; PMCID: PMC12009791.

12: Divvela SSK, Gallorini M, Gellisch M, Patel GD, Saso L, Brand-Saberi B.
Navigating redox imbalance: the role of oxidative stress in embryonic
development and long-term health outcomes. Front Cell Dev Biol. 2025 Mar
26;13:1521336. doi: 10.3389/fcell.2025.1521336. PMID: 40206404; PMCID:
PMC11979171.

13: Ebrahimi R, Mohammadpour A, Medoro A, Davinelli S, Saso L, Miroliaei M.
Exploring the links between polyphenols, Nrf2, and diabetes: A review. Biomed
Pharmacother. 2025 May;186:118020. doi: 10.1016/j.biopha.2025.118020. Epub 2025
Mar 31. PMID: 40168723.

14: Moosavi F, Divar M, Khabnadideh S, Tavakkoli M, Mohabbati M, Saso L,
Poustforoosh A, Firuzi O. Spiroindoline quinazolinedione derivatives as
inhibitors of P-glycoprotein: potential agents for overcoming multidrug
resistance in cancer therapy. Mol Divers. 2025 Mar 19. doi:
10.1007/s11030-025-11150-5. Epub ahead of print. PMID: 40106127.

15: Nazari S, Mosaffa F, Poustforoosh A, Saso L, Firuzi O, Moosavi F. c-MET
tyrosine kinase inhibitors reverse multidrug resistance in breast cancer cells
by targeting ABCG2 transporter. J Pharm Pharmacol. 2025 May 2;77(5):685-697.
doi: 10.1093/jpp/rgaf008. PMID: 40053482.

16: Mohammadi S, Mortazavi M, Poustforoosh A, Moosavi F, Saso L, Edraki N,
Firuzi O. Novel spiroisatin-pyranopyrazole hybrids as anticancer agents with
TrkC inhibitory potential. J Biomol Struct Dyn. 2025 Mar 2:1-14. doi:
10.1080/07391102.2025.2472404. Epub ahead of print. PMID: 40025803.

17: Phogat P, Bansal A, Nain N, Khan S, Saso L, Kukreti S. Quest for space:
Tenacity of DNA, Protein, and Lipid macromolecules in intracellular crowded
environment. Biomol Concepts. 2025 Mar 1;16(1). doi: 10.1515/bmc-2025-0053.
PMID: 40022308.

18: Mardaneh P, Pirhadi S, Mohabbati M, Khoshneviszadeh M, Rezaei Z, Saso L,
Edraki N, Firuzi O. Design, synthesis and pharmacological evaluation of
1,4-naphthoquinone- 1,2,3-triazole hybrids as new anticancer agents with multi-
kinase inhibitory activity. Sci Rep. 2025 Feb 24;15(1):6639. doi:
10.1038/s41598-025-87483-w. PMID: 39994286; PMCID: PMC11850817.

19: Matlin SA, Hanefeld J, Corte-Real A, da Cunha PR, de Gruchy T, Manji KN,
Netto G, Nunes T, Şanlıer İ, Takian A, Zaman MH, Saso L. Digital solutions for
migrant and refugee health: a framework for analysis and action. Lancet Reg
Health Eur. 2024 Dec 26;50:101190. doi: 10.1016/j.lanepe.2024.101190. PMID:
39816782; PMCID: PMC11732709.

20: Egbujor MC, Tucci P, Saso L. Bioactive Sulfonamides Derived from Amino
Acids: Their Synthesis and Pharmacological Activities. Mini Rev Med Chem. 2025
Jan 13. doi: 10.2174/0113895575353663241129064820. Epub ahead of print. PMID:
39812049.

21: Medoro A, Scapagnini G, Brogi S, Jafar TH, Trung TT, Saso L, Davinelli S.
Carotenoid Interactions with PCSK9: Exploring Novel Cholesterol-Lowering
Strategies. Pharmaceuticals (Basel). 2024 Nov 27;17(12):1597. doi:
10.3390/ph17121597. PMID: 39770439; PMCID: PMC11676125.

22: Kanojia N, Guin D, Machahary N, Thakran S, Kukal S, Thakur J, Panda B, Singh
P, Srivastava A, Singh P, Grover S, Singh A, Sardana V, Saso L, Kukreti S,
Kukreti R. Effect of antiepileptic drug monotherapy on endogenous sex hormonal
profile in men and women with epilepsy. Epilepsy Behav. 2025 Feb;163:110220.
doi: 10.1016/j.yebeh.2024.110220. Epub 2024 Dec 17. PMID: 39693860.

23: Nazari S, Poustforoosh A, Paul PR, Kukreti R, Tavakkoli M, Saso L, Firuzi O,
Moosavi F. c-MET tyrosine kinase inhibitors reverse drug resistance mediated by
the ATP-binding cassette transporter B1 (ABCB1) in cancer cells. 3 Biotech. 2025
Jan;15(1):2. doi: 10.1007/s13205-024-04162-9. Epub 2024 Dec 4. PMID: 39650809;
PMCID: PMC11618280.

24: Temaj G, Chichiarelli S, Saha S, Telkoparan-Akillilar P, Nuhii N,
Hadziselimovic R, Saso L. Alternative Splicing: A Potential Therapeutic Target
in Hematological Malignancies. Hematol Rep. 2024 Oct 29;16(4):682-697. doi:
10.3390/hematolrep16040066. PMID: 39584923; PMCID: PMC11587037.

25: Medoro A, Jafar TH, Sallustio F, Scapagnini G, Saso L, Davinelli S.
Computational Assessment of Carotenoids as Keap1-Nrf2 Protein-Protein
Interaction Inhibitors: Implications for Antioxidant Strategies. Biochemistry
(Mosc). 2024 Oct;89(10):1681-1691. doi: 10.1134/S0006297924100031. PMID:
39523109.

26: Saha S, Buttari B, Saso L. Editorial: Modulation of oxidative stress and
inflammation via the NRF2 signaling pathway. Front Pharmacol. 2024 Sep
17;15:1483289. doi: 10.3389/fphar.2024.1483289. PMID: 39359243; PMCID:
PMC11445792.

27: Moosavi F, Hassani B, Nazari S, Saso L, Firuzi O. Targeting DNA damage
response in pancreatic ductal adenocarcinoma: A review of preclinical and
clinical evidence. Biochim Biophys Acta Rev Cancer. 2024 Nov;1879(6):189185.
doi: 10.1016/j.bbcan.2024.189185. Epub 2024 Sep 24. PMID: 39326802.

28: Petrikonis K, Bernatoniene J, Kopustinskiene DM, Casale R, Davinelli S, Saso
L. The Antinociceptive Role of Nrf2 in Neuropathic Pain: From Mechanisms to
Clinical Perspectives. Pharmaceutics. 2024 Aug 15;16(8):1068. doi:
10.3390/pharmaceutics16081068. PMID: 39204413; PMCID: PMC11358986.

29: Letafati A, Taghiabadi Z, Ardekani OS, Abbasi S, Najafabadi AQ, Jazi NN,
Soheili R, Rodrigo R, Yavarian J, Saso L. Unveiling the intersection:
ferroptosis in influenza virus infection. Virol J. 2024 Aug 12;21(1):185. doi:
10.1186/s12985-024-02462-3. PMID: 39135112; PMCID: PMC11321227.

30: Sever B, Saso L, Tzoneva R, Onnis V, Ciftci H. Editorial: Multi-targeted
tyrosine kinase inhibitors in the treatment of cancer and neurodegenerative
disorders. Front Chem. 2024 Jul 26;12:1460347. doi: 10.3389/fchem.2024.1460347.
PMID: 39130801; PMCID: PMC11310111.

31: Bagheri S, Saboury AA, Saso L. Sequence of Molecular Events in the
Development of Alzheimer's Disease: Cascade Interactions from Beta-Amyloid to
Other Involved Proteins. Cells. 2024 Jul 31;13(15):1293. doi:
10.3390/cells13151293. PMID: 39120323; PMCID: PMC11312137.

32: Di Veroli B, Bentanachs R, Roglans N, Alegret M, Giona L, Profumo E, Berry
A, Saso L, Laguna JC, Buttari B. Sex Differences Affect the NRF2 Signaling
Pathway in the Early Phase of Liver Steatosis: A High-Fat-Diet-Fed Rat Model
Supplemented with Liquid Fructose. Cells. 2024 Jul 24;13(15):1247. doi:
10.3390/cells13151247. PMID: 39120278; PMCID: PMC11312139.

33: Marini P, Maccarrone M, Saso L, Tucci P. The Effect of Phytocannabinoids and
Endocannabinoids on Nrf2 Activity in the Central Nervous System and Periphery.
Neurol Int. 2024 Jul 18;16(4):776-789. doi: 10.3390/neurolint16040057. PMID:
39051218; PMCID: PMC11270200.

34: Pinilla-González V, Rojas-Solé C, Gómez-Hevia F, González-Fernández T,
Cereceda-Cornejo A, Chichiarelli S, Saso L, Rodrigo R. Tapping into Nature's
Arsenal: Harnessing the Potential of Natural Antioxidants for Human Health and
Disease Prevention. Foods. 2024 Jun 25;13(13):1999. doi: 10.3390/foods13131999.
PMID: 38998505; PMCID: PMC11241326.

35: Letafati A, Taghiabadi Z, Zafarian N, Tajdini R, Mondeali M, Aboofazeli A,
Chichiarelli S, Saso L, Jazayeri SM. Emerging paradigms: unmasking the role of
oxidative stress in HPV-induced carcinogenesis. Infect Agent Cancer. 2024 Jul
2;19(1):30. doi: 10.1186/s13027-024-00581-8. PMID: 38956668; PMCID: PMC11218399.

36: Temaj G, Chichiarelli S, Telkoparan-Akillilar P, Saha S, Nuhii N,
Hadziselimovic R, Saso L. P53: A key player in diverse cellular processes
including nuclear stress and ribosome biogenesis, highlighting potential
therapeutic compounds. Biochem Pharmacol. 2024 Aug;226:116332. doi:
10.1016/j.bcp.2024.116332. Epub 2024 Jun 1. PMID: 38830426.

37: Subošić B, Zdravković V, Ješić M, Munjas J, Kovačević S, Guzonjić A,
Mitrović J, Saso L, Đuričić I, Kotur-Stevuljević J. Childhood obesity
accelerates biological ageing: is oxidative stress a link? Br J Nutr. 2024 Jul
28;132(2):227-235. doi: 10.1017/S0007114524000898. Epub 2024 May 13. PMID:
38736405.

38: Temaj G, Chichiarelli S, Telkoparan-Akillilar P, Saha S, Nuhii N,
Hadziselimovic R, Saso L. Advances in molecular function of UPF1 in Cancer. Arch
Biochem Biophys. 2024 Jun;756:109989. doi: 10.1016/j.abb.2024.109989. Epub 2024
Apr 14. PMID: 38621446.

39: Maccari S, Profumo E, Saso L, Marano G, Buttari B. Propranolol Promotes
Monocyte-to-Macrophage Differentiation and Enhances Macrophage Anti-Inflammatory
and Antioxidant Activities by NRF2 Activation. Int J Mol Sci. 2024 Mar
26;25(7):3683. doi: 10.3390/ijms25073683. PMID: 38612493; PMCID: PMC11011821.

40: Pinilla-González V, Montecinos-Barrientos B, Martin-Kommer C, Chichiarelli
S, Saso L, Rodrigo R. Exploring antioxidant strategies in the pathogenesis of
ALS. Open Life Sci. 2024 Mar 28;19(1):20220842. doi: 10.1515/biol-2022-0842.
PMID: 38585631; PMCID: PMC10997151.

41: Ganguly U, Singh S, Bir A, Ghosh A, Chakrabarti SS, Saini RV, Saso L,
Bisaglia M, Chakrabarti S. Alpha-synuclein interaction with mitochondria is the
final mechanism of ferroptotic death induced by erastin in SH-SY5Y cells. Free
Radic Res. 2024 Mar;58(3):217-228. doi: 10.1080/10715762.2024.2336563. Epub 2024
Apr 5. PMID: 38572725.

42: Culletta G, Buttari B, Arese M, Brogi S, Almerico AM, Saso L, Tutone M.
Natural products as non-covalent and covalent modulators of the KEAP1/NRF2
pathway exerting antioxidant effects. Eur J Med Chem. 2024 Apr 15;270:116355.
doi: 10.1016/j.ejmech.2024.116355. Epub 2024 Mar 26. PMID: 38555855.

43: Briones-Valdivieso C, Briones F, Orellana-Urzúa S, Chichiarelli S, Saso L,
Rodrigo R. Novel Multi-Antioxidant Approach for Ischemic Stroke Therapy
Targeting the Role of Oxidative Stress. Biomedicines. 2024 Feb 23;12(3):501.
doi: 10.3390/biomedicines12030501. PMID: 38540114; PMCID: PMC10968576.

44: El Kebbaj R, Bouchab H, Tahri-Joutey M, Rabbaa S, Limami Y, Nasser B,
Egbujor MC, Tucci P, Andreoletti P, Saso L, Cherkaoui-Malki M. The Potential
Role of Major Argan Oil Compounds as Nrf2 Regulators and Their Antioxidant
Effects. Antioxidants (Basel). 2024 Mar 13;13(3):344. doi:
10.3390/antiox13030344. PMID: 38539877; PMCID: PMC10967919.

45: Egbujor MC, Olaniyan OT, Emeruwa CN, Saha S, Saso L, Tucci P. An insight
into role of amino acids as antioxidants via NRF2 activation. Amino Acids. 2024
Mar 20;56(1):23. doi: 10.1007/s00726-024-03384-8. PMID: 38506925; PMCID:
PMC10954862.

46: Yaylim İ, Aru M, Farooqi AA, Hakan MT, Buttari B, Arese M, Saso L.
Regulation of Nrf2/Keap1 signaling pathway in cancer drug resistance by
galectin-1: cellular and molecular implications. Cancer Drug Resist. 2024 Feb
29;7:8. doi: 10.20517/cdr.2023.79. PMID: 38434765; PMCID: PMC10905161.

47: Mendonça ELSS, Xavier JA, Fragoso MBT, Silva MO, Escodro PB, Oliveira ACM,
Tucci P, Saso L, Goulart MOF. E-Stilbenes: General Chemical and
Biological Aspects, Potential Pharmacological Activity Based on the Nrf2
Pathway. Pharmaceuticals (Basel). 2024 Feb 9;17(2):232. doi: 10.3390/ph17020232.
PMID: 38399446; PMCID: PMC10891666.

48: Signorini C, Saso L, Ghareghomi S, Telkoparan-Akillilar P, Collodel G,
Moretti E. Redox Homeostasis and Nrf2-Regulated Mechanisms Are Relevant to Male
Infertility. Antioxidants (Basel). 2024 Feb 3;13(2):193. doi:
10.3390/antiox13020193. PMID: 38397791; PMCID: PMC10886271.

49: Egbujor MC, Tucci P, Buttari B, Nwobodo DC, Marini P, Saso L.
Phenothiazines: Nrf2 activation and antioxidant effects. J Biochem Mol Toxicol.
2024 Mar;38(3):e23661. doi: 10.1002/jbt.23661. PMID: 38369721.

50: Nazari S, Mosaffa F, Poustforoosh A, Mortazavi M, Saso L, Firuzi O, Moosavi
F. Foretinib, a c-MET receptor tyrosine kinase inhibitor, tackles multidrug
resistance in cancer cells by inhibiting ABCB1 and ABCG2 transporters. Toxicol
Appl Pharmacol. 2024 Mar;484:116866. doi: 10.1016/j.taap.2024.116866. Epub 2024
Feb 15. PMID: 38367674.

51: Rahban M, Joushi S, Bashiri H, Saso L, Sheibani V. Characterization of
prevalent tyrosine kinase inhibitors and their challenges in glioblastoma
treatment. Front Chem. 2024 Jan 8;11:1325214. doi: 10.3389/fchem.2023.1325214.
PMID: 38264122; PMCID: PMC10804459.

52: Rojas-Solé C, Pinilla-González V, Lillo-Moya J, González-Fernández T, Saso
L, Rodrigo R. Integrated approach to reducing polypharmacy in older people:
exploring the role of oxidative stress and antioxidant potential therapy. Redox
Rep. 2024 Dec;29(1):2289740. doi: 10.1080/13510002.2023.2289740. Epub 2023 Dec
18. PMID: 38108325; PMCID: PMC10732214.

53: Rahban M, Ahmad F, Piatyszek MA, Haertlé T, Saso L, Saboury AA.
Stabilization challenges and aggregation in protein-based therapeutics in the
pharmaceutical industry. RSC Adv. 2023 Dec 11;13(51):35947-35963. doi:
10.1039/d3ra06476j. PMID: 38090079; PMCID: PMC10711991.

54: Ates I, Yılmaz AD, Buttari B, Arese M, Saso L, Suzen S. A Review of the
Potential of Nuclear Factor [Erythroid-Derived 2]-like 2 Activation in
Autoimmune Diseases. Brain Sci. 2023 Oct 30;13(11):1532. doi:
10.3390/brainsci13111532. PMID: 38002492; PMCID: PMC10669303.

55: Vukelić D, Baralić K, Marić Đ, Đukic-Ćosić D, Bulat Z, Panieri E, Saso L,
Djordjevic AB. Hepato-renal toxicity of low dose metal(oid)s mixture in real-
life risk simulation in rats: Effects on Nrf2/HO-1 signalling and redox status.
Sci Total Environ. 2024 Jan 15;908:168352. doi: 10.1016/j.scitotenv.2023.168352.
Epub 2023 Nov 10. PMID: 37952665.

56: Medoro A, Saso L, Scapagnini G, Davinelli S. NRF2 signaling pathway and
telomere length in aging and age-related diseases. Mol Cell Biochem. 2024
Oct;479(10):2597-2613. doi: 10.1007/s11010-023-04878-x. Epub 2023 Nov 2. PMID:
37917279; PMCID: PMC11455797.

57: Saha S, Saso L. Pharmacological Modulation of Oxidative Stress. Int J Mol
Sci. 2023 Sep 22;24(19):14455. doi: 10.3390/ijms241914455. PMID: 37833901;
PMCID: PMC10572500.

58: Temaj G, Chichiarelli S, Saha S, Telkoparan-Akillilar P, Nuhii N,
Hadziselimovic R, Saso L. An intricate rewiring of cancer metabolism via
alternative splicing. Biochem Pharmacol. 2023 Nov;217:115848. doi:
10.1016/j.bcp.2023.115848. Epub 2023 Oct 7. PMID: 37813165.

59: Kaftan G, Erdoğan MA, El-Shazly M, Lu MC, Shih SP, Lin HY, Saso L, Armagan
G. Heteronemin promotes iron-dependent cell death in pancreatic cancer. Naunyn
Schmiedebergs Arch Pharmacol. 2024 Mar;397(3):1865-1874. doi:
10.1007/s00210-023-02736-7. Epub 2023 Sep 29. PMID: 37773525.

60: Orellana-Urzúa S, Briones-Valdivieso C, Chichiarelli S, Saso L, Rodrigo R.
Potential Role of Natural Antioxidants in Countering Reperfusion Injury in Acute
Myocardial Infarction and Ischemic Stroke. Antioxidants (Basel). 2023 Sep
13;12(9):1760. doi: 10.3390/antiox12091760. PMID: 37760064; PMCID: PMC10525378.

61: Bresciani G, Manai F, Davinelli S, Tucci P, Saso L, Amadio M. Novel
potential pharmacological applications of dimethyl fumarate-an overview and
update. Front Pharmacol. 2023 Sep 7;14:1264842. doi: 10.3389/fphar.2023.1264842.
PMID: 37745068; PMCID: PMC10512734.

62: Mortazavi M, Eskandari M, Moosavi F, Damghani T, Khoshneviszadeh M, Pirhadi
S, Saso L, Edraki N, Firuzi O. Novel quinazoline-1,2,3-triazole hybrids with
anticancer and MET kinase targeting properties. Sci Rep. 2023 Sep 6;13(1):14685.
doi: 10.1038/s41598-023-41283-2. PMID: 37673888; PMCID: PMC10482942.

63: Sorice M, Profumo E, Capozzi A, Recalchi S, Riitano G, Di Veroli B, Saso L,
Buttari B. Oxidative Stress as a Regulatory Checkpoint in the Production of
Antiphospholipid Autoantibodies: The Protective Role of NRF2 Pathway.
Biomolecules. 2023 Aug 5;13(8):1221. doi: 10.3390/biom13081221. PMID: 37627286;
PMCID: PMC10452087.

64: Leseva MN, Buttari B, Saso L, Dimitrova PA. Infection Meets Inflammation:
N6-Methyladenosine, an Internal Messenger RNA Modification as a Tool for
Pharmacological Regulation of Host-Pathogen Interactions. Biomolecules. 2023 Jun
29;13(7):1060. doi: 10.3390/biom13071060. PMID: 37509095; PMCID: PMC10377384.

65: Gallorini M, Carradori S, Panieri E, Sova M, Saso L. Modulation of NRF2:
Biological Dualism in Cancer, Targets and Possible Therapeutic Applications.
Antioxid Redox Signal. 2024 Apr;40(10-12):636-662. doi: 10.1089/ars.2022.0213.
Epub 2023 Sep 6. PMID: 37470218.

66: Suzen S, Saso L. Melatonin as mitochondria-targeted drug. Adv Protein Chem
Struct Biol. 2023;136:249-276. doi: 10.1016/bs.apcsb.2023.03.006. Epub 2023 Apr
22. PMID: 37437980.

67: Gjorgieva Ackova D, Maksimova V, Smilkov K, Buttari B, Arese M, Saso L.
Alkaloids as Natural NRF2 Inhibitors: Chemoprevention and Cytotoxic Action in
Cancer. Pharmaceuticals (Basel). 2023 Jun 7;16(6):850. doi: 10.3390/ph16060850.
PMID: 37375797; PMCID: PMC10300961.

68: Włodarczyk L, Cichoń N, Karbownik MS, Saso L, Saluk J, Miller E. Circulating
Serum VEGF, IGF-1 and MMP-9 and Expression of Their Genes as Potential
Prognostic Markers of Recovery in Post-Stroke Rehabilitation-A Prospective
Observational Study. Brain Sci. 2023 May 23;13(6):846. doi:
10.3390/brainsci13060846. PMID: 37371326; PMCID: PMC10296181.

69: Divar M, Edraki N, Damghani T, Moosavi F, Mohabbati M, Alipour A, Pirhadi S,
Saso L, Khabnadideh S, Firuzi O. Novel spiroindoline quinazolinedione
derivatives as anticancer agents and potential FLT3 kinase inhibitors. Bioorg
Med Chem. 2023 Jul 15;90:117367. doi: 10.1016/j.bmc.2023.117367. Epub 2023 Jun
10. PMID: 37348260.

70: Saha S, Saso L, Armagan G. Cancer Prevention and Therapy by Targeting
Oxidative Stress Pathways. Molecules. 2023 May 24;28(11):4293. doi:
10.3390/molecules28114293. PMID: 37298769; PMCID: PMC10254771.

71: Todorov L, Saso L, Kostova I. Antioxidant Activity of Coumarins and Their
Metal Complexes. Pharmaceuticals (Basel). 2023 Apr 26;16(5):651. doi:
10.3390/ph16050651. PMID: 37242434; PMCID: PMC10220850.

72: Saha S, Saso L, Trofimov AV, Yablonskaya OI. Chemical, Biological and
Biomedical Aspects of Bioantioxidants. Biomedicines. 2023 May 6;11(5):1377. doi:
10.3390/biomedicines11051377. PMID: 37239048; PMCID: PMC10216159.

73: Ahmed S, Alam W, Aschner M, Filosa R, Cheang WS, Jeandet P, Saso L, Khan H.
Marine Cyanobacterial Peptides in Neuroblastoma: Search for Better Therapeutic
Options. Cancers (Basel). 2023 Apr 27;15(9):2515. doi: 10.3390/cancers15092515.
PMID: 37173981; PMCID: PMC10177606.

74: Carvalho AN, Branco V, van Horssen J, Saso L. Editorial: Redox-signaling in
neurodegenerative diseases: biomarkers, targets, and therapies. Front Cell
Neurosci. 2023 Apr 20;17:1198669. doi: 10.3389/fncel.2023.1198669. PMID:
37153636; PMCID: PMC10158492.

75: Singh A, Kukal S, Kanojia N, Singh M, Saso L, Kukreti S, Kukreti R. Lipid
mediated brain disorders: A perspective. Prostaglandins Other Lipid Mediat. 2023
Aug;167:106737. doi: 10.1016/j.prostaglandins.2023.106737. Epub 2023 Apr 20.
PMID: 37086954.

76: Iranpanah A, Kooshki L, Moradi SZ, Saso L, Fakhri S, Khan H. The Exosome-
Mediated PI3K/Akt/mTOR Signaling Pathway in Neurological Diseases.
Pharmaceutics. 2023 Mar 21;15(3):1006. doi: 10.3390/pharmaceutics15031006. PMID:
36986865; PMCID: PMC10057486.

77: Egbujor MC, Tucci P, Onyeije UC, Emeruwa CN, Saso L. NRF2 Activation by
Nitrogen Heterocycles: A Review. Molecules. 2023 Mar 18;28(6):2751. doi:
10.3390/molecules28062751. PMID: 36985723; PMCID: PMC10058096.

78: Kostić K, Brborić J, Delogu G, Simić MR, Samardžić S, Maksimović Z, Dettori
MA, Fabbri D, Kotur-Stevuljević J, Saso L. Antioxidant Activity of Natural
Phenols and Derived Hydroxylated Biphenyls. Molecules. 2023 Mar 14;28(6):2646.
doi: 10.3390/molecules28062646. PMID: 36985617; PMCID: PMC10053952.

79: Méndez-Valdés G, Gómez-Hevia F, Lillo-Moya J, González-Fernández T, Abelli
J, Cereceda-Cornejo A, Bragato MC, Saso L, Rodrigo R. Endostatin and Cancer
Therapy: A Novel Potential Alternative to Anti-VEGF Monoclonal Antibodies.
Biomedicines. 2023 Feb 27;11(3):718. doi: 10.3390/biomedicines11030718. PMID:
36979697; PMCID: PMC10045088.

80: Temaj G, Telkoparan-Akillilar P, Nuhii N, Chichiarelli S, Saha S, Saso L.
Recoding of Nonsense Mutation as a Pharmacological Strategy. Biomedicines. 2023
Feb 22;11(3):659. doi: 10.3390/biomedicines11030659. PMID: 36979640; PMCID:
PMC10044939.

81: Ghareghomi S, Moosavi-Movahedi F, Saso L, Habibi-Rezaei M, Khatibi A, Hong
J, Moosavi-Movahedi AA. Modulation of Nrf2/HO-1 by Natural Compounds in Lung
Cancer. Antioxidants (Basel). 2023 Mar 16;12(3):735. doi:
10.3390/antiox12030735. PMID: 36978983; PMCID: PMC10044870.

82: Ahmed S, Alam W, Alsharif KF, Aschner M, Alzahrani FM, Saso L, Khan H.
Therapeutic potential of marine peptides in malignant melanoma. Environ Res.
2023 Jun 15;227:115771. doi: 10.1016/j.envres.2023.115771. Epub 2023 Mar 24.
PMID: 36967001.

83: Mazurakova A, Koklesova L, Csizmár SH, Samec M, Brockmueller A, Šudomová M,
Biringer K, Kudela E, Pec M, Samuel SM, Kassayova M, Hassan STS, Smejkal K,
Shakibaei M, Büsselberg D, Saso L, Kubatka P, Golubnitschaja O. Significance of
flavonoids targeting PI3K/Akt/HIF-1α signaling pathway in therapy-resistant
cancer cells - A potential contribution to the predictive, preventive, and
personalized medicine. J Adv Res. 2024 Jan;55:103-118. doi:
10.1016/j.jare.2023.02.015. Epub 2023 Mar 4. PMID: 36871616; PMCID: PMC10770105.

84: Méndez-Valdés G, Gómez-Hevia F, Bragato MC, Lillo-Moya J, Rojas-Solé C, Saso
L, Rodrigo R. Antioxidant Protection against Trastuzumab Cardiotoxicity in
Breast Cancer Therapy. Antioxidants (Basel). 2023 Feb 10;12(2):457. doi:
10.3390/antiox12020457. PMID: 36830015; PMCID: PMC9952697.

85: Zhang J, Semlali A, Maycotte P, Saso L. Editorial: Targeting redox
regulation and autophagy systems for cancer therapy. Front Oncol. 2023 Jan
31;13:1146670. doi: 10.3389/fonc.2023.1146670. PMID: 36798822; PMCID:
PMC9927638.

86: Jacques MT, Saso L, Farina M. LPS-Activated Microglial Cell-Derived
Conditioned Medium Protects HT22 Neuronal Cells against Glutamate-Induced
Ferroptosis. Int J Mol Sci. 2023 Feb 2;24(3):2910. doi: 10.3390/ijms24032910.
PMID: 36769233; PMCID: PMC9917809.

87: Shahcheraghi SH, Salemi F, Small S, Syed S, Salari F, Alam W, Cheang WS,
Saso L, Khan H. Resveratrol regulates inflammation and improves oxidative stress
via Nrf2 signaling pathway: Therapeutic and biotechnological prospects.
Phytother Res. 2023 Apr;37(4):1590-1605. doi: 10.1002/ptr.7754. Epub 2023 Feb 8.
PMID: 36752350.

88: Méndez-Valdés G, Pérez-Carreño V, Bragato MC, Hundahl M, Chichiarelli S,
Saso L, Rodrigo R. Cardioprotective Mechanisms against Reperfusion Injury in
Acute Myocardial Infarction: Targeting Angiotensin II Receptors. Biomedicines.
2022 Dec 22;11(1):17. doi: 10.3390/biomedicines11010017. PMID: 36672525; PMCID:
PMC9856001.

89: Hekmat A, Saso L, Lather V, Pandita D, Kostova I, Saboury AA. Recent
Advances in Nanomaterials of Group XIV Elements of Periodic Table in Breast
Cancer Treatment. Pharmaceutics. 2022 Nov 29;14(12):2640. doi:
10.3390/pharmaceutics14122640. PMID: 36559135; PMCID: PMC9781757.

90: Hussain Y, Abdullah, Khan F, Alsharif KF, Alzahrani KJ, Saso L, Khan H.
Regulatory Effects of Curcumin on Platelets: An Update and Future Directions.
Biomedicines. 2022 Dec 8;10(12):3180. doi: 10.3390/biomedicines10123180. PMID:
36551934; PMCID: PMC9775400.

91: Abelli J, Méndez-Valdés G, Gómez-Hevia F, Bragato MC, Chichiarelli S, Saso
L, Rodrigo R. Potential Antioxidant Multitherapy against Complications Occurring
in Sepsis. Biomedicines. 2022 Dec 1;10(12):3088. doi:
10.3390/biomedicines10123088. PMID: 36551843; PMCID: PMC9775396.

92: Ávila C, Vinay JI, Arese M, Saso L, Rodrigo R. Antioxidant Intervention
against Male Infertility: Time to Design Novel Strategies. Biomedicines. 2022
Nov 28;10(12):3058. doi: 10.3390/biomedicines10123058. PMID: 36551814; PMCID:
PMC9775742.

93: Tucci P, Lattanzi R, Severini C, Saso L. Nrf2 Pathway in Huntington's
Disease (HD): What Is Its Role? Int J Mol Sci. 2022 Dec 3;23(23):15272. doi:
10.3390/ijms232315272. PMID: 36499596; PMCID: PMC9739588.

94: Mortazavi M, Divar M, Damghani T, Moosavi F, Saso L, Pirhadi S,
Khoshneviszadeh M, Edraki N, Firuzi O. Study of the anticancer effect of new
quinazolinone hydrazine derivatives as receptor tyrosine kinase inhibitors.
Front Chem. 2022 Nov 17;10:969559. doi: 10.3389/fchem.2022.969559. PMID:
36465863; PMCID: PMC9713320.

95: Davinelli S, Medoro A, Intrieri M, Saso L, Scapagnini G, Kang JX. Targeting
NRF2-KEAP1 axis by Omega-3 fatty acids and their derivatives: Emerging
opportunities against aging and diseases. Free Radic Biol Med. 2022 Nov
20;193(Pt 2):736-750. doi: 10.1016/j.freeradbiomed.2022.11.017. Epub 2022 Nov
17. PMID: 36402440.

96: Gallorini M, Carradori S, Resende DISP, Saso L, Ricci A, Palmeira A, Cataldi
A, Pinto M, Sousa E. Natural and Synthetic Xanthone Derivatives Counteract
Oxidative Stress via Nrf2 Modulation in Inflamed Human Macrophages. Int J Mol
Sci. 2022 Nov 1;23(21):13319. doi: 10.3390/ijms232113319. PMID: 36362104; PMCID:
PMC9659273.

97: Profumo E, Maggi E, Arese M, Di Cristofano C, Salvati B, Saso L, Businaro R,
Buttari B. Neuropeptide Y Promotes Human M2 Macrophage Polarization and Enhances
p62/SQSTM1-Dependent Autophagy and NRF2 Activation. Int J Mol Sci. 2022 Oct
27;23(21):13009. doi: 10.3390/ijms232113009. PMID: 36361795; PMCID: PMC9653849.

98: Sharifi S, Dalir Abdolahinia E, Ghavimi MA, Dizaj SM, Aschner M, Saso L,
Khan H. Effect of Curcumin-Loaded Mesoporous Silica Nanoparticles on the Head
and Neck Cancer Cell Line, HN5. Curr Issues Mol Biol. 2022 Oct
27;44(11):5247-5259. doi: 10.3390/cimb44110357. PMID: 36354669; PMCID:
PMC9688994.

99: Magnifico MC, Xhani M, Sprovera B, Buttari B, Abballe G, Desideri F, Panieri
E, Saso L, Arese M. Nitro-Oxidative Stress and Mitochondrial Dysfunction in
Human Cell Lines Exposed to the Environmental Contaminants PFOA and BPA. Front
Biosci (Landmark Ed). 2022 Oct 27;27(10):292. doi: 10.31083/j.fbl2710292. PMID:
36336871.

100: Panieri E, Telkoparan-Akillilar P, Saso L. NRF2, a crucial modulator of
skin cells protection against vitiligo, psoriasis, and cancer. Biofactors. 2023
Mar;49(2):228-250. doi: 10.1002/biof.1912. Epub 2022 Oct 30. PMID: 36310374.

101: Ghareghomi S, Habibi-Rezaei M, Arese M, Saso L, Moosavi-Movahedi AA. Nrf2
Modulation in Breast Cancer. Biomedicines. 2022 Oct 21;10(10):2668. doi:
10.3390/biomedicines10102668. PMID: 36289931; PMCID: PMC9599257.

102: Ahmed S, Alam W, Aschner M, Alsharif KF, Albrakati A, Saso L, Khan H.
Natural products targeting the ATR-CHK1 signaling pathway in cancer therapy.
Biomed Pharmacother. 2022 Nov;155:113797. doi: 10.1016/j.biopha.2022.113797.
Epub 2022 Oct 8. PMID: 36271573; PMCID: PMC9590097.

103: Buttari B, Arese M, Oberley-Deegan RE, Saso L, Chatterjee A. NRF2: A
crucial regulator for mitochondrial metabolic shift and prostate cancer
progression. Front Physiol. 2022 Sep 23;13:989793. doi:
10.3389/fphys.2022.989793. PMID: 36213236; PMCID: PMC9540504.

104: Roy A, Bera S, Saso L, Dwarakanath BS. Role of autophagy in tumor response
to radiation: Implications for improving radiotherapy. Front Oncol. 2022 Sep
12;12:957373. doi: 10.3389/fonc.2022.957373. PMID: 36172166; PMCID: PMC9510974.

105: Temaj G, Chichiarelli S, Eufemi M, Altieri F, Hadziselimovic R, Farooqi AA,
Yaylim I, Saso L. Ribosome-Directed Therapies in Cancer. Biomedicines. 2022 Aug
26;10(9):2088. doi: 10.3390/biomedicines10092088. PMID: 36140189; PMCID:
PMC9495564.

106: Ourhzif EM, Ricelli A, Stagni V, Cirigliano A, Rinaldi T, Bouissane L, Saso
L, Chalard P, Troin Y, Khouili M, Akssira M. Antifungal and Cytotoxic Activity
of Diterpenes and Bisnorsesquiterpenoides from the Latex of Euphorbia
resinifera Berg. Molecules. 2022 Aug 16;27(16):5234. doi:
10.3390/molecules27165234. PMID: 36014466; PMCID: PMC9413093.

107: Matlin SA, Smith AC, Merone J, LeVoy M, Shah J, Vanbiervliet F,
Vandentorren S, Vearey J, Saso L. The Challenge of Reaching Undocumented
Migrants with COVID-19 Vaccination. Int J Environ Res Public Health. 2022 Aug
12;19(16):9973. doi: 10.3390/ijerph19169973. PMID: 36011606; PMCID: PMC9408401.

108: Gray NE, Farina M, Tucci P, Saso L. The Role of the NRF2 Pathway in
Maintaining and Improving Cognitive Function. Biomedicines. 2022 Aug
21;10(8):2043. doi: 10.3390/biomedicines10082043. PMID: 36009590; PMCID:
PMC9405981.

109: Egbujor MC, Buttari B, Profumo E, Telkoparan-Akillilar P, Saso L. An
Overview of NRF2-Activating Compounds Bearing α,β-Unsaturated Moiety and Their
Antioxidant Effects. Int J Mol Sci. 2022 Jul 30;23(15):8466. doi:
10.3390/ijms23158466. PMID: 35955599; PMCID: PMC9369284.

110: Panieri E, Pinho SA, Afonso GJM, Oliveira PJ, Cunha-Oliveira T, Saso L.
NRF2 and Mitochondrial Function in Cancer and Cancer Stem Cells. Cells. 2022 Aug
4;11(15):2401. doi: 10.3390/cells11152401. PMID: 35954245; PMCID: PMC9367715.

111: Šola KF, Vladimir-Knežević S, Hrabač P, Mucalo I, Saso L, Verbanac D. The
effect of multistrain probiotics on functional constipation in the elderly: a
randomized controlled trial. Eur J Clin Nutr. 2022 Dec;76(12):1675-1681. doi:
10.1038/s41430-022-01189-0. Epub 2022 Aug 4. PMID: 35927504; PMCID: PMC9708599.

112: Ahmed S, Alam W, Jeandet P, Aschner M, Alsharif KF, Saso L, Khan H.
Therapeutic Potential of Marine Peptides in Prostate Cancer: Mechanistic
Insights. Mar Drugs. 2022 Jul 22;20(8):466. doi: 10.3390/md20080466. PMID:
35892934; PMCID: PMC9330892.

113: Egbujor MC, Petrosino M, Zuhra K, Saso L. The Role of Organosulfur
Compounds as Nrf2 Activators and Their Antioxidant Effects. Antioxidants
(Basel). 2022 Jun 26;11(7):1255. doi: 10.3390/antiox11071255. PMID: 35883746;
PMCID: PMC9311638.

114: Hussain Y, Khan H, Alsharif KF, Hayat Khan A, Aschner M, Saso L. The
Therapeutic Potential of Kaemferol and Other Naturally Occurring Polyphenols
Might Be Modulated by Nrf2-ARE Signaling Pathway: Current Status and Future
Direction. Molecules. 2022 Jun 28;27(13):4145. doi: 10.3390/molecules27134145.
PMID: 35807387; PMCID: PMC9268049.

115: Hussain Y, Khan H, Alotaibi G, Khan F, Alam W, Aschner M, Jeandet P, Saso
L. How Curcumin Targets Inflammatory Mediators in Diabetes: Therapeutic Insights
and Possible Solutions. Molecules. 2022 Jun 24;27(13):4058. doi:
10.3390/molecules27134058. PMID: 35807304; PMCID: PMC9268477.

116: Hussain Y, Khan H, Alam W, Aschner M, Abdullah, Alsharif KF, Saso L.
Flavonoids Targeting the mTOR Signaling Cascades in Cancer: A Potential
Crosstalk in Anti-Breast Cancer Therapy. Oxid Med Cell Longev. 2022 Jun
27;2022:4831833. doi: 10.1155/2022/4831833. PMID: 35795855; PMCID: PMC9252758.

117: Temaj G, Saha S, Dragusha S, Ejupi V, Buttari B, Profumo E, Beqa L, Saso L.
Ribosomopathies and cancer: pharmacological implications. Expert Rev Clin
Pharmacol. 2022 Jun;15(6):729-746. doi: 10.1080/17512433.2022.2098110. Epub 2022
Jul 15. PMID: 35787725.

118: Suzen S, Tucci P, Profumo E, Buttari B, Saso L. A Pivotal Role of Nrf2 in
Neurodegenerative Disorders: A New Way for Therapeutic Strategies.
Pharmaceuticals (Basel). 2022 May 31;15(6):692. doi: 10.3390/ph15060692. PMID:
35745610; PMCID: PMC9227112.

119: González-Montero J, Chichiarelli S, Eufemi M, Altieri F, Saso L, Rodrigo R.
Ascorbate as a Bioactive Compound in Cancer Therapy: The Old Classic Strikes
Back. Molecules. 2022 Jun 14;27(12):3818. doi: 10.3390/molecules27123818. PMID:
35744943; PMCID: PMC9229419.

120: Yaylım İ, Farooqi AA, Telkoparan-Akillilar P, Saso L. Interplay between
Non-Coding RNAs and NRF2 in Different Cancers: Spotlight on MicroRNAs and Long
Non-Coding RNAs. J Pharmacol Exp Ther. 2023 Jan;384(1):28-34. doi:
10.1124/jpet.121.000921. Epub 2022 Jun 6. PMID: 35667688.

121: Deus CM, Teixeira J, Raimundo N, Tucci P, Borges F, Saso L, Oliveira PJ.
Modulation of cellular redox environment as a novel therapeutic strategy for
Parkinson's disease. Eur J Clin Invest. 2022 Oct;52(10):e13820. doi:
10.1111/eci.13820. Epub 2022 Jun 13. PMID: 35638352.

122: Saso L, Reza A, Ng E, Nguyen K, Lin S, Zhang P, Fantozzi PJ, Armagan G,
Romeo U, Cirillo N. A Comprehensive Analysis of the Role of Oxidative Stress in
the Pathogenesis and Chemoprevention of Oral Submucous Fibrosis. Antioxidants
(Basel). 2022 Apr 28;11(5):868. doi: 10.3390/antiox11050868. PMID: 35624733;
PMCID: PMC9137539.

123: Janoušek J, Pilařová V, Macáková K, Nomura A, Veiga-Matos J, Silva DDD,
Remião F, Saso L, Malá-Ládová K, Malý J, Nováková L, Mladěnka P. Vitamin D:
sources, physiological role, biokinetics, deficiency, therapeutic use, toxicity,
and overview of analytical methods for detection of vitamin D and its
metabolites. Crit Rev Clin Lab Sci. 2022 Dec;59(8):517-554. doi:
10.1080/10408363.2022.2070595. Epub 2022 May 16. PMID: 35575431.

124: Shahcheraghi SH, Salemi F, Alam W, Ashworth H, Saso L, Khan H, Lotfi M. The
Role of NRF2/KEAP1 Pathway in Glioblastoma: Pharmacological Implications. Med
Oncol. 2022 May 15;39(5):91. doi: 10.1007/s12032-022-01693-0. PMID: 35568790.

125: Hussain Y, Abdullah, Alsharif KF, Aschner M, Theyab A, Khan F, Saso L, Khan
H. Therapeutic Role of Carotenoids in Blood Cancer: Mechanistic Insights and
Therapeutic Potential. Nutrients. 2022 May 6;14(9):1949. doi:
10.3390/nu14091949. PMID: 35565917; PMCID: PMC9104383.

126: Guin D, Yadav S, Singh P, Singh P, Thakran S, Kukal S, Kanojia N, Paul PR,
Pattnaik B, Sardana V, Grover S, Hasija Y, Saso L, Agrawal A, Kukreti R. Human
genetic factors associated with pneumonia risk, a cue for COVID-19
susceptibility. Infect Genet Evol. 2022 Aug;102:105299. doi:
10.1016/j.meegid.2022.105299. Epub 2022 May 8. PMID: 35545162; PMCID:
PMC9080029.

127: Rodrigo R, Retamal C, Schupper D, Vergara-Hernández D, Saha S, Profumo E,
Buttari B, Saso L. Antioxidant Cardioprotection against Reperfusion Injury:
Potential Therapeutic Roles of Resveratrol and Quercetin. Molecules. 2022 Apr
15;27(8):2564. doi: 10.3390/molecules27082564. PMID: 35458766; PMCID:
PMC9027566.

128: Mohi-Ud-Din R, Mir RH, Wani TU, Alsharif KF, Alam W, Albrakati A, Saso L,
Khan H. The Regulation of Endoplasmic Reticulum Stress in Cancer: Special
Focuses on Luteolin Patents. Molecules. 2022 Apr 12;27(8):2471. doi:
10.3390/molecules27082471. PMID: 35458669; PMCID: PMC9031790.

129: Zaki M, Loubidi M, Bilgiç T, Birim D, Akssira M, Dagcı T, Berteina-Raboin
S, Saso L, Khouili M, Armagan G. Design, Synthesis, and Biological Evaluation of
Novel Tomentosin Derivatives in NMDA-Induced Excitotoxicity. Pharmaceuticals
(Basel). 2022 Mar 30;15(4):421. doi: 10.3390/ph15040421. PMID: 35455419; PMCID:
PMC9027110.

130: Gall Trošelj K, Tomljanović M, Jaganjac M, Matijević Glavan T, Čipak
Gašparović A, Milković L, Borović Šunjić S, Buttari B, Profumo E, Saha S, Saso
L, Žarković N. Oxidative Stress and Cancer Heterogeneity Orchestrate NRF2 Roles
Relevant for Therapy Response. Molecules. 2022 Feb 22;27(5):1468. doi:
10.3390/molecules27051468. PMID: 35268568; PMCID: PMC8912061.

131: Panieri E, Baralic K, Djukic-Cosic D, Buha Djordjevic A, Saso L. PFAS
Molecules: A Major Concern for the Human Health and the Environment. Toxics.
2022 Jan 18;10(2):44. doi: 10.3390/toxics10020044. PMID: 35202231; PMCID:
PMC8878656.

132: Ahmed NS, Samec M, Liskova A, Kubatka P, Saso L. Tamoxifen and oxidative
stress: an overlooked connection. Discov Oncol. 2021 May 27;12(1):17. doi:
10.1007/s12672-021-00411-y. PMID: 35201439; PMCID: PMC8777555.

133: Singh A, Kukreti R, Saso L, Kukreti S. Mechanistic Insight into Oxidative
Stress-Triggered Signaling Pathways and Type 2 Diabetes. Molecules. 2022 Jan
30;27(3):950. doi: 10.3390/molecules27030950. PMID: 35164215; PMCID: PMC8840622.

134: Khan H, Alam W, Alsharif KF, Aschner M, Pervez S, Saso L. Alkaloids and
Colon Cancer: Molecular Mechanisms and Therapeutic Implications for Cell Cycle
Arrest. Molecules. 2022 Jan 28;27(3):920. doi: 10.3390/molecules27030920. PMID:
35164185; PMCID: PMC8838632.

135: Saso L, Chakrabarti S, Miller E. Pharmaceutical and Pharmacological Aspects
of Modulation of Oxidative Stress 2020. Oxid Med Cell Longev. 2022 Jan
27;2022:9842198. doi: 10.1155/2022/9842198. PMID: 35154577; PMCID: PMC8825295.

136: Brizzolari A, Foti MC, Saso L, Ciuffreda P, Lazarević J, Santaniello E.
Evaluation of the radical scavenging activity of some representative isoprenoid
and aromatic cytokinin ribosides (N⁶-substituted adenosines) by
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137: Saha S, Buttari B, Profumo E, Tucci P, Saso L. A Perspective on Nrf2
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138: Davinelli S, Saso L, D'Angeli F, Calabrese V, Intrieri M, Scapagnini G.
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139: Dimić DS, Kaluđerović GN, Avdović EH, Milenković DA, Živanović MN, Potočňák
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140: Shahcheraghi SH, Salemi F, Peirovi N, Ayatollahi J, Alam W, Khan H, Saso L.
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141: Mishra MK, Kukal S, Paul PR, Bora S, Singh A, Kukreti S, Saso L, Muthusamy
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142: Talwar P, Kushwaha S, Rawat C, Kaur H, Srivastava A, Agarwal R, Chandna P,
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143: Seminotti B, Grings M, Tucci P, Leipnitz G, Saso L. Nuclear Factor
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144: Ghareghomi S, Rahban M, Moosavi-Movahedi Z, Habibi-Rezaei M, Saso L,
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145: Costa M, Sezgin-Bayindir Z, Losada-Barreiro S, Paiva-Martins F, Saso L,
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146: Banerjee A, Kanwar M, Das Mohapatra PK, Saso L, Nicoletti M, Maiti S.
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147: Matlin SA, Karadag O, Brando CR, Góis P, Karabey S, Khan MMH, Saleh S,
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148: Rahman N, Khan H, Zia A, Khan A, Fakhri S, Aschner M, Gul K, Saso L. Bcl-2
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149: Bisenieks E, Vigante B, Petrovska R, Turovska B, Muhamadejev R, Soloduns V,
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150: Kukal S, Guin D, Rawat C, Bora S, Mishra MK, Sharma P, Paul PR, Kanojia N,
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151: Marjanovic A, Djedjibegovic J, Lugusic A, Sober M, Saso L. Multivariate
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152: Rodrigo R, Prieto JC, Aguayo R, Ramos C, Puentes Á, Gajardo A, Panieri E,
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153: Pierzynowska K, Gaffke L, Cyske Z, Węgrzyn G, Buttari B, Profumo E, Saso L.
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154: Tber Z, Loubidi M, Jouha J, Hdoufane I, Erdogan MA, Saso L, Armagan G,
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155: Koklesova L, Liskova A, Samec M, Zhai K, Al-Ishaq RK, Bugos O, Šudomová M,
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156: Farina M, Vieira LE, Buttari B, Profumo E, Saso L. The Nrf2 Pathway in
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157: Kumar A, Kaushik P, Incerpi S, Pedersen JZ, Goel S, Prasad AK, Rohil V,
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158: Szczuko M, Kikut J, Szczuko U, Szydłowska I, Nawrocka-Rutkowska J, Ziętek
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159: Todorov L, Saso L, Benarous K, Traykova M, Linani A, Kostova I. Synthesis,
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160: Matlin SA, Orcutt M, Bojorquez I, Caman OK, Severoni S, Spiegel P, Veizis
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161: Verma S, Singh P, Khurana S, Ganguly NK, Kukreti R, Saso L, Rana DS, Taneja
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162: Ucar BI, Ucar G, Saha S, Buttari B, Profumo E, Saso L. Pharmacological
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163: Avdović EH, Petrović IP, Stevanović MJ, Saso L, Dimitrić Marković JM,
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164: Ganguly U, Kaur U, Chakrabarti SS, Sharma P, Agrawal BK, Saso L,
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165: Sezgin-Bayindir Z, Losada-Barreiro S, Bravo-Díaz C, Sova M, Kristl J, Saso
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166: Lillo-Moya J, Rojas-Solé C, Muñoz-Salamanca D, Panieri E, Saso L, Rodrigo
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167: Kancheva VD, Dettori MA, Fabbri D, Alov P, Angelova SE, Slavova-Kazakova
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168: Aleksic M, Kalezic A, Saso L, Jankovic A, Korac B, Korac A. The Unity of
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169: Süntar I, Çetinkaya S, Panieri E, Saha S, Buttari B, Profumo E, Saso L.
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170: Verbanac D, Čeri A, Hlapčić I, Shakibaei M, Brockmueller A, Krušlin B,
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171: Buha A, Baralić K, Djukic-Cosic D, Bulat Z, Tinkov A, Panieri E, Saso L.
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172: Brboric J, Klisic A, Kotur-Stevuljevic J, Delogu G, Gjorgieva Ackova D,
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173: Telkoparan-Akillilar P, Panieri E, Cevik D, Suzen S, Saso L. Therapeutic
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174: Tascioglu Aliyev A, Panieri E, Stepanić V, Gurer-Orhan H, Saso L.
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175: Ulker OC, Panieri E, Suzen S, Jaganjac M, Zarkovic N, Saso L. Short
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176: Banerjee A, Ganguly U, Saha S, Chakrabarti S, Saini RV, Rawal RK, Saso L,
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177: Lattanzi R, Severini C, Maftei D, Saso L, Badiani A. The Role of
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178: Egbujor MC, Saha S, Buttari B, Profumo E, Saso L. Activation of Nrf2
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179: Damghani T, Moosavi F, Khoshneviszadeh M, Mortazavi M, Pirhadi S, Kayani Z,
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180: Urrutia I, Martín-Nieto A, Martínez R, Casanovas-Marsal JO, Aguayo A, Del
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181: García-Castaño A, Madariaga L, Gómez-Conde S, Cordo CLR, López-Iglesias M,
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182: Maslovarić I, Ilić V, Drvenica I, Stančić A, Mojsilović S, Kukolj T,
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183: Zaiter J, Hibot A, Hafid A, Khouili M, Neves CMB, Simões MMQ, Neves MGPMS,
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184: Panieri E, Saso L. Inhibition of the NRF2/KEAP1 Axis: A Promising
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185: Tancheva L, Lazarova M, Saso L, Kalfin R, Stefanova M, Uzunova D, Atanasov
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186: Samec M, Liskova A, Koklesova L, Mersakova S, Strnadel J, Kajo K, Pec M,
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187: Viayna E, Coquelle N, Cieslikiewicz-Bouet M, Cisternas P, Oliva CA,
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188: Guin D, Rani J, Singh P, Grover S, Bora S, Talwar P, Karthikeyan M,
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189: Ricelli A, Gionfra F, Percario Z, De Angelis M, Primitivo L, Bonfantini V,
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190: Rahban M, Habibi-Rezaei M, Mazaheri M, Saso L, Moosavi-Movahedi AA. Anti-
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191: Cunha-Oliveira T, Montezinho L, Mendes C, Firuzi O, Saso L, Oliveira PJ,
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192: Todorov L, Traykova M, Saso L, Kostova I. In Vitro Interaction of
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193: Saha S, Buttari B, Panieri E, Profumo E, Saso L. An Overview of Nrf2
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194: Nabavi SM, Devi KP, Sathya S, Sanches-Silva A, Joanna L, Talarek S, Xu S,
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195: Benarous K, Bou-Salah L, Linani A, Yousfi M, Kostova I, Saso L. Lanthanide
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196: Thakran S, Guin D, Singh P, Singh P, Kukal S, Rawat C, Yadav S, Kushwaha
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197: Saha S, Profumo E, Togna AR, Riganò R, Saso L, Buttari B. Lupeol
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