LAURA STRONATI

GENERAL INFORMATION
Full Name: LAURA STRONATI
Citizenship: ITALIAN

PRESENT POSITION
01/11/2023 - today, Full Professor (BIO/13), Sapienza University of Rome, Department of Molecular Medicine
01/11/2019- Today, Coordinator of PhD in Human Biology and Medical Genetics, Sapienza University of Rome, Department of Molecular Medicine
09/03/2023- Today, Member of the Departmental Commission “Terza Missione”, Sapienza University of Rome, Department of Molecular Medicine

ACADEMIC APPOINTMENTS
30/10/2015 -30/10/2023, Associate Professor (BIO/13), Sapienza University of Rome, Department of Cellular Biotechnology and Haematology

OTHER APPOINTMENTS
2011-2015, Senior Researcher, ENEA (Italian Agency for New Technology, Energy and Sustainable Economic Development)
1990-2011, Researcher, ENEA
1989-1990, Consultant, ENEA

EDUCATION AND TRAINING
University graduation: 1986, Sapienza University of Rome, Biological Sciences, full marks and honors.
Post-graduate studies: 1986-89, Post-graduate guest, ENEA
National qualification: 2012, Italian Ministry of Education, Qualification University and Research (MIUR) - ANVUR, Abilitazione Scientifica Nazionale professore di II FASCIA 05/F1;
2012, Italian Ministry of Education, Qualification University and Research (MIUR) - ANVUR, Abilitazione Scientifica Nazionale professore di II FASCIA 05/E2;
2013, Italian Ministry of Education, Qualification University and Research (MIUR) - ANVUR, Abilitazione Scientifica Nazionale professore di II FASCIA 06/N1;
2016, Italian Ministry of Education, Qualification University and Research (MIUR) - ANVUR, Abilitazione Scientifica Nazionale professore di I FASCIA 05/F1.

TEACHING
2023-today, Sapienza University of Rome, Cell biology in the graduate program of Medicine High Technology (Coordinator)
2020-2023, Sapienza University of Rome, Genetics in the graduate program of Medicine High Technology
2020-today, Sapienza University of Rome, Applied Biology in the graduate program of Dietetics
2021-today, Sapienza University of Rome, Molecular Biology at Master of II level in Gastrointestinal imaging
2022-today, Sapienza University of Rome, Molecular Biology at Master of II level in Colon-protctology
2016-today, Sapienza University of Rome, Cell biology in the graduate program of Biotechnology (Coordinator 1 semester)
2016-today, Sapienza University of Rome, Applied biology in the graduate program of Biomedical Laboratory Techniques

MENTORING EXPERIENCE
-Supervisor of Bachelor and Master’s degree students in Biology and Biotechnology.
-Supervisor of PhD students.
-Supervisor of Master II Level students.

EDITORIAL ACTIVITY
2022-to present, Associate Editor of Frontiers in Immunology
2018-to present, Associate Editor of Digestive and Liver Disease (Elsevier)

FUNDING (last 5 years)
2022-24, “Creazione di un’infrastruttura di innovazione, servizio, formazione, terza missione e ricerca aperta e distribuita sul territorio, finalizzata a supportare la creazione e sviluppo di dispositivi medici”, (Role: I), Rome Technopole - Progetto Flagship 4 (Prot. RT422184581348BF), (1.416.250,00 euro);
2023-25, "Integrated phenotyping of the Gut-platelet-Liver AXIS in the progression of chronic liver disease. (iGAL-AXIS), (Role: I), PRIN: PROGETTI DI RICERCA DI RILEVANTE INTERESSE NAZIONALE – Bando 2022 Prot. 2022C7ZR3W (258,041 euro);
2020-22, ”Immunosensori modificati con materiale nanostrutturato per la rilevazione di biomarcatori fecali di infiammazione e permeabilità intestinale: un importante progresso nella gestione di malattie ad alta prevalenza” PaGIMeter, (Role: I), Progetto Strategico della Regione Lazio prot. n. A320-2019-28176 del 29/07/2019 (252,172,69 euro);
2022, “Multiomics and machine learning to predict response to drug therapies in pediatric Eosinophilic Esophagitis”, (Role: PI), Progetto Ateneo Grande Prot. RG1221816730E1E0 (73.890,08 euro);
2021, "Examining intestinal fibrosis in patients with Crohn's disease using organoid models", (Role: PI), Progetto Ateneo medio Prot. RM12117A757B9F08 (10.000,00 euro);
2021, “Studio in vitro degli effetti di Scutellaria Baicalensis Georgi e Boswellia serrata sulla fibrosi intestinale”, (Role: PI), Progetto finanziato da Cadigroup Farmaceutici Srl (15.000,00 euro);
2020, “Characterization of the esophageal tissue by single cell RNA sequencing in pediatric patients with oesinophilic esophagitis and identification of novel biomarkers to predict the early-relapse to the disease”, (Role: PI), Progetto Ateneo medio Prot. RM120172B43331E2 (10.000,00 euro);

RESEARCH ACTIVITIES
Keywords: Immunopathogenesis, chronic inflammatory disorders, inflammation, fibrosis, GI tract.
- Immunopathogenesis of inflammatory bowel diseases (IBD) and eosinophilic esophagitis (EoE)
- Genetics of inflammatory bowel diseases
- Mechanisms of interaction between commensal microbiota and innate immune system
- Non-pharmacological therapies for the cure of inflammatory immune-mediated diseases
- Inflammatory processes in gut-liver and gut-brain axis

SCIENTIFIC ACHIEVEMENTS
Papers: 97 (https://pubmed.ncbi.nlm.nih.gov/)
Hirsch (H) index (https://www.scopus.com/): 40
Normalized H index* (https://www.scopus.com/): 1,4

*H index divided by the academic seniority

BOOKS
Cucchiara S and Stronati L. Crohn’s disease in children: a multidisciplinary approach. Eds Roberto Tersigni and Cosimo Prantera, Springer 2009, Vol. unico, chp 15, 169-186. ISBN: 8847014719 |

PATENT
2014, Titolo: “Uso di HMGB1 come marcatore biologico di infiammazione”, Numero di pubblicazione: WO 2014/017466 A1, N. rilascio:1406051, Data di rilascio: 06.02.2014.
2019, Titolo: “Uso della proteina inibitore 2 della dissociazione di RHO GDP come marcatore diagnostico e prognostico delle malattie infiammatorie intestinali” Numero di pubblicazione: WO 2019/016719 A, N. rilascio: 102017000083055, Data di rilascio: 08.10.2019