1049267 - MODELLING AND SIMULATION OF BIOMOLECULAR DYNAMICAL SYSTEMS |
This course aims to provide students with a practical and hands-on experience with common modeling and simulation tools in molecular biology. It would be expected that after completing this course a student would be able to model and simulate using Matlab a biomolecular systems like, for example, a gene regulatory network using the appropriate methodology. Further, students will understand the basic theory behind these modeling tecniques and critically analyze the results of their analysis. |
Terzo anno |
Primo semestre |
6 |
ING-INF/06 |
|
1049268 - SIGNAL PROCESSING AND INFORMATION THEORY |
|
Terzo anno |
Primo semestre |
6 |
ING-INF/03 |
|
1049269 - ALGORITHMS |
this course is an introduction to algorithms with special emphasis given to those algorithmic problems and techniques that have the greatest impact for bioinformatics. |
Terzo anno |
Primo semestre |
6 |
INF/01 |
|
1049270 - COMPLEX BIOMOLECULAR NETWORKS |
The course aims to provide basics concepts and tools for complex networks analysis. The attendee will be able to apply complex networks concepts to biological networks and explore the underlying process and molecular related issues. |
Terzo anno |
Primo semestre |
6 |
ING-INF/05 |
|
1049271 - PLANT FUNCTIONAL GENOMICS |
The aim of the course is to provide a theoretical knowledge of plant genomes, and practical explanation of the techniques used in plant functional genomics, i.e. a large-scale analysis of the function of the different gene products to understand how the genome generates the phenotype of the plant. Insights will be given into the new information that will be generated from whole genome-/proteome-/metabolome analysis. The course will cover the following concepts: array and sequencing based methods; reverse and forward genetics; comparison of plant genomes; epigenomics; proteomics and metabolomics. Also covered are robotization, miniaturization (single-cell studies) and high-throughput-screenings. Finally, the course will introduce methods for visualization and analysis of high-density data. |
Terzo anno |
Primo semestre |
6 |
BIO/04 |
|
1049272 - PRINCIPLES OF GENERAL PATHOLOGY |
|
Terzo anno |
Primo semestre |
6 |
MED/46 |
|
1049273 - OPTIMIZATION METHODS FOR COMPUTATIONAL BIOLOGY |
We aim to introduce students to the analysis of decision problems that arise in bioinformatics and health management. Students would be able to: model as mathematical programming problem to be used as a support to the decision maker, use algorithm suitable to each model for the solution, make post-optimality analysis. |
Terzo anno |
Primo semestre |
6 |
MAT/09 |
|
1049285 - BIOINFORMATICS IN PLANT PATHOLOGY |
Recent advances in -omics technology, namely genomics, proteomics and metabolomics allow to go deeper into the understanding of the subtle mechanism underlying host-pathogen interactions. This is made possible by next generation sequencers that uncover entire genome or exome of host and pathogens while interacting, skipping complicate procedures for separating the two challengers. Moreover, we are moving faster in re-shaping plant pathology from the one disease-one pathogen dogma, as embodied in Koch's postulate, to the pathobiome concept. Meta-omic tools shed light on the inter-reign network originating the disease of the host in its complexity. The analysis and understanding of the huge amount of data generated by a single experiment represents currently the classical bottleneck. In relation to this, bioinformatics plays a crucial role in data capture, analysis and integration. Plant pathologists have to answer to very concrete and problematic question, today, more, and more in the next future: food security, food safety and food quality. Actually, plant disease burden current food production, accounting for more than 40% of food losses. Climate change and globalization enhance pathogens ability and mobility worldwide. Nevertheless, for environmental as well as political reasons, pathogens cannot be controlled anymore by using pesticides and/or GMO plants. A more sustainable, "green" and integrated pest management is needed. A modern plant pathologist has to face this complex reality, plan experiments at real scale, "sucks the marrow out of -omics" (par. Walt Whitman) by using bioinformatics tools, individuate biocontrol agents and stimulate plant self-defences. In relation to this, the main aim of this course is forming young scientists in managing plant diseases tout court by the mean of the -omics plus bioinformatics tools. |
Terzo anno |
Primo semestre |
6 |
AGR/12 |
|
1049267 - MODELLING AND SIMULATION OF BIOMOLECULAR DYNAMICAL SYSTEMS |
This course aims to provide students with a practical and hands-on experience with common modeling and simulation tools in molecular biology. It would be expected that after completing this course a student would be able to model and simulate using Matlab a biomolecular systems like, for example, a gene regulatory network using the appropriate methodology. Further, students will understand the basic theory behind these modeling tecniques and critically analyze the results of their analysis. |
Terzo anno |
Secondo semestre |
6 |
ING-INF/06 |
|
1049268 - SIGNAL PROCESSING AND INFORMATION THEORY |
|
Terzo anno |
Secondo semestre |
6 |
ING-INF/03 |
|
1049269 - ALGORITHMS |
this course is an introduction to algorithms with special emphasis given to those algorithmic problems and techniques that have the greatest impact for bioinformatics. |
Terzo anno |
Secondo semestre |
6 |
INF/01 |
|
1049270 - COMPLEX BIOMOLECULAR NETWORKS |
The course aims to provide basics concepts and tools for complex networks analysis. The attendee will be able to apply complex networks concepts to biological networks and explore the underlying process and molecular related issues. |
Terzo anno |
Secondo semestre |
6 |
ING-INF/05 |
|
1049271 - PLANT FUNCTIONAL GENOMICS |
The aim of the course is to provide a theoretical knowledge of plant genomes, and practical explanation of the techniques used in plant functional genomics, i.e. a large-scale analysis of the function of the different gene products to understand how the genome generates the phenotype of the plant. Insights will be given into the new information that will be generated from whole genome-/proteome-/metabolome analysis. The course will cover the following concepts: array and sequencing based methods; reverse and forward genetics; comparison of plant genomes; epigenomics; proteomics and metabolomics. Also covered are robotization, miniaturization (single-cell studies) and high-throughput-screenings. Finally, the course will introduce methods for visualization and analysis of high-density data. |
Terzo anno |
Secondo semestre |
6 |
BIO/04 |
|
1049272 - PRINCIPLES OF GENERAL PATHOLOGY |
|
Terzo anno |
Secondo semestre |
6 |
MED/46 |
|
1049273 - OPTIMIZATION METHODS FOR COMPUTATIONAL BIOLOGY |
We aim to introduce students to the analysis of decision problems that arise in bioinformatics and health management. Students would be able to: model as mathematical programming problem to be used as a support to the decision maker, use algorithm suitable to each model for the solution, make post-optimality analysis. |
Terzo anno |
Secondo semestre |
6 |
MAT/09 |
|
1049285 - BIOINFORMATICS IN PLANT PATHOLOGY |
Recent advances in -omics technology, namely genomics, proteomics and metabolomics allow to go deeper into the understanding of the subtle mechanism underlying host-pathogen interactions. This is made possible by next generation sequencers that uncover entire genome or exome of host and pathogens while interacting, skipping complicate procedures for separating the two challengers. Moreover, we are moving faster in re-shaping plant pathology from the one disease-one pathogen dogma, as embodied in Koch's postulate, to the pathobiome concept. Meta-omic tools shed light on the inter-reign network originating the disease of the host in its complexity. The analysis and understanding of the huge amount of data generated by a single experiment represents currently the classical bottleneck. In relation to this, bioinformatics plays a crucial role in data capture, analysis and integration. Plant pathologists have to answer to very concrete and problematic question, today, more, and more in the next future: food security, food safety and food quality. Actually, plant disease burden current food production, accounting for more than 40% of food losses. Climate change and globalization enhance pathogens ability and mobility worldwide. Nevertheless, for environmental as well as political reasons, pathogens cannot be controlled anymore by using pesticides and/or GMO plants. A more sustainable, "green" and integrated pest management is needed. A modern plant pathologist has to face this complex reality, plan experiments at real scale, "sucks the marrow out of -omics" (par. Walt Whitman) by using bioinformatics tools, individuate biocontrol agents and stimulate plant self-defences. In relation to this, the main aim of this course is forming young scientists in managing plant diseases tout court by the mean of the -omics plus bioinformatics tools. |
Terzo anno |
Secondo semestre |
6 |
AGR/12 |
|