Orari di ricevimento
lun 14-16
Curriculum
Personal information
First name(s) / Surname(s)
Marzia Perluigi
Address(es)
Department of Biochemical Sciences “A. Rossi Fanelli”
Sapienza University of Rome, P.le Aldo Moro, 5 00185 Rome (IT)
Telephone(s)
+39 0649910885
Fax(es)
+39 064440062
E-mail
Marzia.perluigi@uniroma1.it; www.lrbn.it
Occupational field
2012- to date: Associate Professor of Biochemistry E1/05 (BIO10)
2013: qualified to Full professor
Work experience
Research interests:
i) molecular mechanisms of neurodegeneration (oxidative stress, autophagy, proteasome system, apoptosis) in mild cognitive impairment and Alzheimer disease, Down Syndrome. Human post-mortem brain samples, cell cultures and animal models of the diseases.
ii) molecular and cellular mechanisms of HPV cell transformation and role of oxidative stress in neoplastic progression of HPV transformed cells. Role of UV irradiation in carcinogenesis
Collaborators:
Prof. DA Butterfield and Prof. Elizabeth Head, University of Kentucky (USA)
Prof. J Vina, University of Valencia (ES)
Prof. A Aronica, University of Amsterdam (NL)
Education and training
November 2006: Research associate in Biochemistry, faculty Pharmacy and Medicine, Sapienza University of Rome
2004-2005: Post-doc fellowship at the Laboratory of Neurochemistry, University of kentucky, Lexington (USA)
2002-2004: post-doc fellowship at the Dep. of Biochemical Sciences Sapienza University of Rome in collaboration with “Regina Elena Institute for Cancer Research” (Agreement)
date
2002: Research Doctorate (PhD) in BIOCHEMISTRY, University of Rome La Sapienza.
1999: Pharmaceutical Chemistry Doctor. 110/110 Magna cum Laude Sapienza University of Rome
Additional information
Teaching activity:
2007- present Sapienza University of Rome, Faculty of Pharmacy and Medicine Biochemistry/Degree Courses Class for Nursing School; Practical Courses on Biochemsitry
2012-present Sapienza University of Rome, Faculty of Pharmacy and Medicine Biochemistry/ International School of Medicine (Ccl F)
2013-present Sapienza University of Rome, Faculty of Pharmacy and Medicine, Chemistry Courses for Biomedical Laboratory Technicians and Radiologist
Society Membership:
SFRR Europe, Trisomy21 Society, Italian Society of Biochemistry
Fundings (last five years)
2012 PI “Impairment of proteostasis network in Down Syndrome brain”, Sapienza University
2013 co-PI “Cognitive decline and neuropsychiatric symptoms in Alzheimer’s disease: can endocannabinoids help?” Sapienza University
2014 PI, Marie Curie Action- BVRISULIN AD
2015 co-PI, SIR Scientific Independence Project, Italian Ministry of University, Research and Education
2016 PI, Intranasal rapamycin for the treatment of Alzheimer-like dementia in Down Syndrome
Jerome Lejeune Foundation (France)
2016 participant-COST-Action OC-2015-1-19651 "Between atom and cell: integrating molecular biophysics approaches for biology and healthcare"
2016 participant- FILASRU-2014-1020 Regione Lazio
Annexes
Scientific Publication
Number of publications =110, http://www.ncbi.nlm.nih.gov/pubmed/?term=perluigi+m
IF tot = 450
h-index = 42
total citations = 4700 (scopus)
Personal information
First name(s) / Surname(s)
Marzia Perluigi
Address(es)
Department of Biochemical Sciences “A. Rossi Fanelli”
Sapienza University of Rome, P.le Aldo Moro, 5 00185 Rome (IT)
Telephone(s)
+39 0649910885
Fax(es)
+39 064440062
E-mail
Marzia.perluigi@uniroma1.it; www.lrbn.it
Occupational field
2012- to date: Associate Professor of Biochemistry E1/05 (BIO10)
2013: qualified to Full professor
Work experience
Research interests:
i) molecular mechanisms of neurodegeneration (oxidative stress, autophagy, proteasome system, apoptosis) in mild cognitive impairment and Alzheimer disease, Down Syndrome. Human post-mortem brain samples, cell cultures and animal models of the diseases.
ii) molecular and cellular mechanisms of HPV cell transformation and role of oxidative stress in neoplastic progression of HPV transformed cells. Role of UV irradiation in carcinogenesis
Collaborators:
Prof. DA Butterfield and Prof. Elizabeth Head, University of Kentucky (USA)
Prof. J Vina, University of Valencia (ES)
Prof. A Aronica, University of Amsterdam (NL)
Education and training
November 2006: Research associate in Biochemistry, faculty Pharmacy and Medicine, Sapienza University of Rome
2004-2005: Post-doc fellowship at the Laboratory of Neurochemistry, University of kentucky, Lexington (USA)
2002-2004: post-doc fellowship at the Dep. of Biochemical Sciences Sapienza University of Rome in collaboration with “Regina Elena Institute for Cancer Research” (Agreement)
date
2002: Research Doctorate (PhD) in BIOCHEMISTRY, University of Rome La Sapienza.
1999: Pharmaceutical Chemistry Doctor. 110/110 Magna cum Laude Sapienza University of Rome
Additional information
Teaching activity:
2007- present Sapienza University of Rome, Faculty of Pharmacy and Medicine Biochemistry/Degree Courses Class for Nursing School; Practical Courses on Biochemsitry
2012-present Sapienza University of Rome, Faculty of Pharmacy and Medicine Biochemistry/ International School of Medicine (Ccl F)
2013-present Sapienza University of Rome, Faculty of Pharmacy and Medicine, Chemistry Courses for Biomedical Laboratory Technicians and Radiologist
Society Membership:
SFRR Europe, Trisomy21 Society, Italian Society of Biochemistry
Fundings (last five years)
2012 PI “Impairment of proteostasis network in Down Syndrome brain”, Sapienza University
2013 co-PI “Cognitive decline and neuropsychiatric symptoms in Alzheimer’s disease: can endocannabinoids help?” Sapienza University
2014 PI, Marie Curie Action- BVRISULIN AD
2015 co-PI, SIR Scientific Independence Project, Italian Ministry of University, Research and Education
2016 PI, Intranasal rapamycin for the treatment of Alzheimer-like dementia in Down Syndrome
Jerome Lejeune Foundation (France)
2016 participant-COST-Action OC-2015-1-19651 "Between atom and cell: integrating molecular biophysics approaches for biology and healthcare"
2016 participant- FILASRU-2014-1020 Regione Lazio
Annexes
Scientific Publication
Number of publications =98, http://www.ncbi.nlm.nih.gov/pubmed/?term=perluigi+m
IF tot = 400
h-index = 36
total citations = 3500 (scopus)