ALESSIA DI COSTANZO

Informazioni personali
Nome DI COSTANZO Alessia
E-mail : alessia.dicostanzo@uniroma1.com
Cittadinanza : ITA
Data di nascita : 30/06/1983
Titoli di studio
17/12/2014 - Dottore di ricerca in TECNOLOGIE BIOMEDICHE IN MEDICINA CLINICA
Università degli Studi di ROMA "La Sapienza"
18/10/2011 - Classe di laurea 9/S Classe delle lauree specialistiche in biotecnologie mediche, veterinarie e farmaceutiche, Università degli Studi di ROMA "La Sapienza"
Esperienze
1. 22/12/2021 - oggi - Ricercatore universitario a t.d.
Ricercatore a t.d. - t.defin. (art. 24 c.3-a L. 240/10)
Università degli Studi di ROMA "La Sapienza" - Dip. L.240/2010 Medicina Traslazionale e di Precisione
2. 01/03/2020 - 20/11/2021 - Assegnista di ricerca
Università degli Studi di ROMA "La Sapienza"
Dip. L.240/2010 Medicina Traslazionale e di Precisione
3. 01/11/2018 - 31/10/2019 - Assegnista di ricerca
Università degli Studi di ROMA "La Sapienza"
Dip. L.240/2010 Medicina interna e specialità mediche
4. 01/07/2017 - 30/06/2018 - Assegnista di ricerca
Università degli Studi di ROMA "La Sapienza"
Dip. L.240/2010 Medicina interna e specialità mediche
5. 01/07/2016 - 30/06/2017 - Assegnista di ricerca
Università degli Studi di ROMA "La Sapienza"
Dip. L.240/2010 Medicina interna e specialità mediche
6. 03/06/2015 - 02/06/2016 - Assegnista di ricerca
Università degli Studi di ROMA "La Sapienza"
Dip. L.240/2010 Medicina interna e specialità mediche
Indicatori Bibliometrici
H-INDEX: 21 (Banca Dati Scopus)
Numero Pubblicazioni: 52
Numero Citazioni Totali: 1269
Elenco dei prodotti della ricerca
1: Tramontano D, Bini S, Maiorca C, Di Costanzo A, Carosi M, Castellese J, Arizaj I, Commodari D, Covino S, Sansone G, Minicocci I, Arca M, D'Erasmo L. Renal Safety Assessment of Lipid-Lowering Drugs: Between Old Certainties and New Questions. Drugs. 2025 Mar 19. doi: 10.1007/s40265-025-02158-0. Epub ahead of print. PMID: 40106181.
2: Tramontano D, D'Erasmo L, Larouche M, Brisson D, Lauzière A, Di Costanzo A, Bini S, Minicocci I, Covino S, Baratta F, Pasquali M, Cerbelli B, Gaudet D, Arca M. The vicious circle of chronic kidney disease and hypertriglyceridemia: What is first, the hen or the egg? Atherosclerosis. 2025 Apr;403:119146. doi: 10.1016/j.atherosclerosis.2025.119146. Epub 2025 Feb 24. PMID: 40056689.
3: Pavanello C, Suppressa P, Castiglione S, Di Costanzo A, Tramontano D, Rizzi L, Steward K, Calabresi L, Arca M, Roeters van Lennep J, D'Erasmo L; Italian and European Working Group on Lomitapide in HoFH. Sex-related differences in response to lomitapide in HoFH: A subanalysis of the Pan-European Lomitapide retrospective observational study. Atherosclerosis. 2025 Feb;401:119089. doi: 10.1016/j.atherosclerosis.2024.119089. Epub 2024 Dec 13. PMID: 39708636.
4: Bini S, Covino S, Minicocci I, D'Erasmo L, Tramontano D, Di Costanzo A, Arca M, Pecce V. Protocol for oil red O staining of low-density lipoproteins for in vivo cell treatment. STAR Protoc. 2024 Dec 20;5(4):103376. doi: 10.1016/j.xpro.2024.103376. Epub 2024 Oct 18. PMID: 39425932; PMCID: PMC11513536.
5: Di Costanzo A, Pirona I, Buonaiuto S, D'Erasmo L, Bini S, Tramontano D, Covino S, Maiorca C, Minicocci I, Sponziello M, Baratta F, Commodari D, Colonna V, Via A, Arca M. Effect of Cholesterol-Lowering Variants in ANGPTL3 and APOB Genes on Liver Disease. J Am Coll Cardiol. 2024 Oct 29;84(18):1767-1770. doi: 10.1016/j.jacc.2024.08.013. Epub 2024 Oct 2. PMID: 39365223.
6: D'Erasmo L, Bini S, Casula M, Gazzotti M, Bertolini S, Calandra S, Tarugi P, Averna M, Iannuzzo G, Fortunato G, Catapano AL, Arca M; LIPIGEN HoFH group. Contemporary lipid-lowering management and risk of cardiovascular events in homozygous familial hypercholesterolaemia: insights from the Italian LIPIGEN Registry. Eur J Prev Cardiol. 2024 Jun 3;31(8):1038-1047. doi: 10.1093/eurjpc/zwae036. PMID: 38374534.
7: Mulder JWCM, Tromp TR, Al-Khnifsawi M, Blom DJ, Chlebus K, Cuchel M, D'Erasmo L, Gallo A, Hovingh GK, Kim NT, Long J, Raal FJ, Schonck WAM, Soran H, Truong TH, Boersma E, Roeters van Lennep JE; Homozygous Familial Hypercholesterolemia International Clinical Collaborators. Sex Differences in Diagnosis, Treatment, and Cardiovascular Outcomes in Homozygous Familial Hypercholesterolemia. JAMA Cardiol. 2024 Apr 1;9(4):313-322. doi: 10.1001/jamacardio.2023.5597. PMID: 38353972; PMCID: PMC10867777.
8: Alieva A, Di Costanzo A, Gazzotti M, Reutova O, Usova E, Bakaleiko V, Arca M, D'Erasmo L, Pellegatta F, Galimberti F, Olmastroni E, Catapano AL, Casula M. Genetic heterogeneity of familial hypercholesterolaemia in two populations from two different countries. Eur J Intern Med. 2024 May;123:65-71. doi: 10.1016/j.ejim.2024.01.010. Epub 2024 Jan 20. PMID: 38245461.
9: D'Erasmo L, Di Martino M, Neufeld T, Fraum TJ, Kang CJ, Burks KH, Di Costanzo A, Minicocci I, Bini S, Maranghi M, Pigna G, Labbadia G, Zheng J, Fierro D, Montali A, Ceci F, Catalano C, Davidson NO, Lucisano G, Nicolucci A, Arca M, Stitziel NO. ANGPTL3 Deficiency and Risk of Hepatic Steatosis. Circulation. 2023 Nov 7;148(19):1479-1489. doi: 10.1161/CIRCULATIONAHA.123.065866. Epub 2023 Sep 15. PMID: 37712257; PMCID: PMC10805521.
10: Bonacina F, Di Costanzo A, Genkel V, Kong XY, Kroon J, Stimjanin E, Tsiantoulas D, Grootaert MO. The heterogeneous cellular landscape of atherosclerosis: Implications for future research and therapies. A collaborative review from the EAS young fellows. Atherosclerosis. 2023 May;372:48-56. doi: 10.1016/j.atherosclerosis.2023.03.021. Epub 2023 Apr 1. PMID: 37030081.
11: Catapano F, Galea N, Pambianchi G, D'Erasmo L, Borrazzo C, Cundari G, Marchitelli L, Maranghi M, Minicocci I, Di Costanzo A, Carbone I, Francone M, Arca M, Catalano C. Effectiveness of clinical scores in predicting coronary artery disease in familial hypercholesterolemia: a coronary computed tomography angiography study. Radiol Med. 2023 Apr;128(4):445-455. doi: 10.1007/s11547-023-01610-z. Epub 2023 Mar 6. PMID: 36877423; PMCID: PMC10119045.
12: Bini S, Tramontano D, Minicocci I, Di Costanzo A, Tambaro F, D'Erasmo L, Arca M. How ANGPTL3 Inhibition Will Help Our Clinical Practice? Curr Atheroscler Rep. 2023 Jan;25(1):19-29. doi: 10.1007/s11883-022-01076-w. Epub 2023 Jan 6. PMID: 36607583.
13: Ossoli A, Minicocci I, Turri M, Di Costanzo A, D'Erasmo L, Bini S, Montavoci L, Veglia F, Calabresi L, Arca M. Genetically determined deficiency of ANGPTL3 does not alter HDL ability to preserve endothelial homeostasis. Biochim Biophys Acta Mol Cell Biol Lipids. 2023 Mar;1868(3):159263. doi: 10.1016/j.bbalip.2022.159263. Epub 2022 Dec 12. PMID: 36521735.
14: Larrey D, D'Erasmo L, O'Brien S, Arca M; Italian Working Group on Lomitapide. Long-term hepatic safety of lomitapide in homozygous familial hypercholesterolaemia. Liver Int. 2023 Feb;43(2):413-423. doi: 10.1111/liv.15497. Epub 2022 Dec 30. PMID: 36520008; PMCID: PMC10107656.
15: Pinzon Grimaldos A, Pacella I, Bini S, Tucci G, Cammarata I, Di Costanzo A, Minicocci I, D'Erasmo L, Arca M, Piconese S. ANGPTL3 deficiency associates with the expansion of regulatory T cells with reduced lipid content. Atherosclerosis. 2022 Dec;362:38-46. doi: 10.1016/j.atherosclerosis.2022.09.014. Epub 2022 Oct 7. PMID: 36253169.
16: Bini S, D'Erasmo L, Astiarraga B, Minicocci I, Palumbo M, Pecce V, Polito L, Di Costanzo A, Haeusler RA, Arca M, Ferrannini E, Camastra S. Differential effects of bariatric surgery on plasma levels of ANGPTL3 and ANGPTL4. Nutr Metab Cardiovasc Dis. 2022 Nov;32(11):2647-2654. doi: 10.1016/j.numecd.2022.08.019. Epub 2022 Sep 1. PMID: 36163215; PMCID: PMC10018753.
17: D'Erasmo L, Giammanco A, Suppressa P, Pavanello C, Iannuzzo G, Di Costanzo A, Tramontano D, Minicocci I, Bini S, Vogt A, Stewards K, Roeters Van Lennep J, Bertolini S, Arca M; Italian and European Working Group on Lomitapide in HoFH. Efficacy of Long-Term Treatment of Autosomal Recessive Hypercholesterolemia With Lomitapide: A Subanalysis of the Pan-European Lomitapide Study. Front Genet. 2022 Aug 22;13:937750. doi: 10.3389/fgene.2022.937750. PMID: 36072671; PMCID: PMC9442671.
18: Baratta F, D'Erasmo L, Bini S, Pastori D, Angelico F, Del Ben M, Arca M, Di Costanzo A. Heterogeneity of non-alcoholic fatty liver disease (NAFLD): Implication for cardiovascular risk stratification. Atherosclerosis. 2022 Sep;357:51-59. doi: 10.1016/j.atherosclerosis.2022.08.011. Epub 2022 Aug 20. PMID: 36058083.
19: Bini S, Pecce V, Di Costanzo A, Polito L, Ghadiri A, Minicocci I, Tambaro F, Covino S, Arca M, D'Erasmo L. The Fibrinogen-like Domain of ANGPTL3 Facilitates Lipolysis in 3T3-L1 Cells by Activating the Intracellular Erk Pathway. Biomolecules. 2022 Apr 16;12(4):585. doi: 10.3390/biom12040585. PMID: 35454174; PMCID: PMC9028860.
20: Baratta F, D'Erasmo L, Di Costanzo A, Umbro I, Pastori D, Angelico F, Del Ben M. Metabolic Syndrome but Not Fatty Liver-Associated Genetic Variants Correlates with Glomerular Renal Function Decline in Patients with Non-Alcoholic Fatty Liver Disease. Biomedicines. 2022 Mar 19;10(3):720. doi: 10.3390/biomedicines10030720. PMID: 35327522; PMCID: PMC8944982.
21: Olmastroni E, Gazzotti M, Arca M, Averna M, Pirillo A, Catapano AL, Casula M; LIPIGEN Study Group†. Twelve Variants Polygenic Score for Low-Density Lipoprotein Cholesterol Distribution in a Large Cohort of Patients With Clinically Diagnosed Familial Hypercholesterolemia With or Without Causative Mutations. J Am Heart Assoc. 2022 Apr 5;11(7):e023668. doi: 10.1161/JAHA.121.023668. Epub 2022 Mar 24. PMID: 35322671; PMCID: PMC9075429.
22: Bailetti D, Sentinelli F, Prudente S, Cimini FA, Barchetta I, Totaro M, Di Costanzo A, Barbonetti A, Leonetti F, Cavallo MG, Baroni MG. Deep Resequencing of 9 Candidate Genes Identifies a Role for ARAP1 and IGF2BP2 in Modulating Insulin Secretion Adjusted for Insulin Resistance in Obese Southern Europeans. Int J Mol Sci. 2022 Jan 22;23(3):1221. doi: 10.3390/ijms23031221. PMID: 35163144; PMCID: PMC8835579.
23: Tromp TR, Hartgers ML, Hovingh GK, Vallejo-Vaz AJ, Ray KK, Soran H, Freiberger T, Bertolini S, Harada-Shiba M, Blom DJ, Raal FJ, Cuchel M; Homozygous Familial Hypercholesterolaemia International Clinical Collaborators. Worldwide experience of homozygous familial hypercholesterolaemia: retrospective cohort study. Lancet. 2022 Feb 19;399(10326):719-728. doi: 10.1016/S0140-6736(21)02001-8. Epub 2022 Jan 28. PMID: 35101175; PMCID: PMC10544712.
24: Pinzon Grimaldos A, Bini S, Pacella I, Rossi A, Di Costanzo A, Minicocci I, D'Erasmo L, Arca M, Piconese S. The role of lipid metabolism in shaping the expansion and the function of regulatory T cells. Clin Exp Immunol. 2022 Jun 11;208(2):181-192. doi: 10.1093/cei/uxab033. PMID: 35020862; PMCID: PMC9188345.
25: D'Erasmo L, Steward K, Cefalù AB, Di Costanzo A, Boersma E, Bini S, Arca M, van Lennep JR; Italian and European Working Group on Lomitapide in HoFH. Efficacy and safety of lomitapide in homozygous familial hypercholesterolaemia: the pan-European retrospective observational study. Eur J Prev Cardiol. 2022 May 5;29(5):832-841. doi: 10.1093/eurjpc/zwab229. Erratum in: Eur J Prev Cardiol. 2022 Oct 18;29(13):1812. doi: 10.1093/eurjpc/zwac062. PMID: 34971394.
26: Di Costanzo A, Minicocci I, D'Erasmo L, Commodari D, Covino S, Bini S, Ghadiri A, Ceci F, Maranghi M, Catapano AL, Gazzotti M, Casula M, Montali A, Arca M. Refinement of pathogenicity classification of variants associated with familial hypercholesterolemia: Implications for clinical diagnosis. J Clin Lipidol. 2021 Nov-Dec;15(6):822-831. doi: 10.1016/j.jacl.2021.10.001. Epub 2021 Oct 11. PMID: 34756585.
27: D'Erasmo L, Gallo A, Cefalù AB, Di Costanzo A, Saheb S, Giammanco A, Averna M, Buonaiuto A, Iannuzzo G, Fortunato G, Puja A, Montalcini T, Pavanello C, Calabresi L, Vigna GB, Bucci M, Bonomo K, Nota F, Sampietro T, Sbrana F, Suppressa P, Sabbà C, Fimiani F, Cesaro A, Calabrò P, Palmisano S, D'Addato S, Pisciotta L, Bertolini S, Bittar R, Kalmykova O, Béliard S, Carrié A, Arca M, Bruckert E. Long-term efficacy of lipoprotein apheresis and lomitapide in the treatment of homozygous familial hypercholesterolemia (HoFH): a cross-national retrospective survey. Orphanet J Rare Dis. 2021 Sep 8;16(1):381. doi: 10.1186/s13023-021-01999-8. PMID: 34496902; PMCID: PMC8427960.
28: D'Erasmo L, Minicocci I, Di Costanzo A, Pigna G, Commodari D, Ceci F, Montali A, Brancato F, Stanca I, Nicolucci A, Ascione A, Galea N, Carbone I, Francone M, Maranghi M, Arca M. Clinical Implications of Monogenic Versus Polygenic Hypercholesterolemia: Long-Term Response to Treatment, Coronary Atherosclerosis Burden, and Cardiovascular Events. J Am Heart Assoc. 2021 May 4;10(9):e018932. doi: 10.1161/JAHA.120.018932. Epub 2021 Apr 23. PMID: 33890476; PMCID: PMC8200757.
29: Di Costanzo A, Perla FM, D'Erasmo L, Arca M, Chiesa C, Pacifico L. Elevated Serum Concentrations of Remnant Cholesterol Associate with Increased Carotid Intima-Media Thickness in Children and Adolescents. J Pediatr. 2021 May;232:133-139.e1. doi: 10.1016/j.jpeds.2021.01.019. Epub 2021 Jan 19. PMID: 33476608.
30: Bini S, D'Erasmo L, Di Costanzo A, Minicocci I, Pecce V, Arca M. The Interplay between Angiopoietin-Like Proteins and Adipose Tissue: Another Piece of the Relationship between Adiposopathy and Cardiometabolic Diseases? Int J Mol Sci. 2021 Jan 13;22(2):742. doi: 10.3390/ijms22020742. PMID: 33451033; PMCID: PMC7828552.
31: Di Costanzo A, Ronca A, D'Erasmo L, Manfredini M, Baratta F, Pastori D, Di Martino M, Ceci F, Angelico F, Del Ben M, Pavanello C, Turri M, Calabresi L, Favari E, Arca M. HDL-Mediated Cholesterol Efflux and Plasma Loading Capacities Are Altered in Subjects with Metabolically- but Not Genetically Driven Non- Alcoholic Fatty Liver Disease (NAFLD). Biomedicines. 2020 Dec 18;8(12):625. doi: 10.3390/biomedicines8120625. PMID: 33352841; PMCID: PMC7766839.
32: D'Erasmo L, Di Costanzo A, Gallo A, Bruckert E, Arca M. ApoCIII: A multifaceted protein in cardiometabolic disease. Metabolism. 2020 Dec;113:154395. doi: 10.1016/j.metabol.2020.154395. Epub 2020 Oct 12. PMID: 33058850.
33: D'Erasmo L, Commodari D, Di Costanzo A, Minicocci I, Polito L, Ceci F, Montali A, Maranghi M, Arca M. Evolving trend in the management of heterozygous familial hypercholesterolemia in Italy: A retrospective, single center, observational study. Nutr Metab Cardiovasc Dis. 2020 Oct 30;30(11):2027-2035. doi: 10.1016/j.numecd.2020.06.028. Epub 2020 Jul 2. PMID: 32830020.
34: D'Erasmo L, Gallo A, Di Costanzo A, Bruckert E, Arca M. Evaluation of efficacy and safety of antisense inhibition of apolipoprotein C-III with volanesorsen in patients with severe hypertriglyceridemia. Expert Opin Pharmacother. 2020 Oct;21(14):1675-1684. doi: 10.1080/14656566.2020.1787380. Epub 2020 Jul 10. PMID: 32646313.
35: Ruhanen H, Haridas PAN, Minicocci I, Taskinen JH, Palmas F, di Costanzo A, D'Erasmo L, Metso J, Partanen J, Dalli J, Zhou Y, Arca M, Jauhiainen M, Käkelä R, Olkkonen VM. ANGPTL3 deficiency alters the lipid profile and metabolism of cultured hepatocytes and human lipoproteins. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Jul;1865(7):158679. doi: 10.1016/j.bbalip.2020.158679. Epub 2020 Mar 6. PMID: 32151767.
36: D'Erasmo L, Di Costanzo A, Arca M. Autosomal recessive hypercholesterolemia: update for 2020. Curr Opin Lipidol. 2020 Apr;31(2):56-61. doi: 10.1097/MOL.0000000000000664. PMID: 32011344.
37: D'Erasmo L, Di Costanzo A, Cassandra F, Minicocci I, Polito L, Montali A, Ceci F, Arca M. Spectrum of Mutations and Long-Term Clinical Outcomes in Genetic Chylomicronemia Syndromes. Arterioscler Thromb Vasc Biol. 2019 Dec;39(12):2531-2541. doi: 10.1161/ATVBAHA.119.313401. Epub 2019 Oct 17. PMID: 31619059.
38: Di Costanzo A, Pacifico L, D'Erasmo L, Polito L, Martino MD, Perla FM, Iezzi L, Chiesa C, Arca M. Nonalcoholic Fatty Liver Disease (NAFLD), But not Its Susceptibility Gene Variants, Influences the Decrease of Kidney Function in Overweight/Obese Children. Int J Mol Sci. 2019 Sep 9;20(18):4444. doi: 10.3390/ijms20184444. PMID: 31505904; PMCID: PMC6769859.
39: Baratta F, Pastori D, Tozzi G, D'Erasmo L, Di Costanzo A, Arca M, Ettorre E, Ginanni Corradini S, Violi F, Angelico F, Del Ben M. Lysosomal acid lipase activity and liver fibrosis in the clinical continuum of non-alcoholic fatty liver disease. Liver Int. 2019 Dec;39(12):2301-2308. doi: 10.1111/liv.14206. Epub 2019 Aug 21. PMID: 31392821.
40: Tikkanen E, Minicocci I, Hällfors J, Di Costanzo A, D'Erasmo L, Poggiogalle E, Donini LM, Würtz P, Jauhiainen M, Olkkonen VM, Arca M. Metabolomic Signature of Angiopoietin-Like Protein 3 Deficiency in Fasting and Postprandial State. Arterioscler Thromb Vasc Biol. 2019 Apr;39(4):665-674. doi: 10.1161/ATVBAHA.118.312021. PMID: 30816800.
41: Di Costanzo A, Pacifico L, Chiesa C, Perla FM, Ceci F, Angeloni A, D'Erasmo L, Di Martino M, Arca M. Genetic and metabolic predictors of hepatic fat content in a cohort of Italian children with obesity. Pediatr Res. 2019 Apr;85(5):671-677. doi: 10.1038/s41390-019-0303-1. Epub 2019 Jan 23. PMID: 30710115; PMCID: PMC6760560.
42: Moulin P, Dufour R, Averna M, Arca M, Cefalù AB, Noto D, D'Erasmo L, Di Costanzo A, Marçais C, Walther LAA, Banach M, Borén J, Cramb R, Gouni-Berthold I, Hughes E, Johnson C, Pintó X, Reiner Ž, van Lennep JR, Soran H, Stefanutti C, Stroes E, Bruckert E. Characterisation of patients with familial chylomicronaemia syndrome (FCS) and multifactorial chylomicronaemia syndrome (MCS): Establishment of an FCS clinical diagnostic score. Data Brief. 2018 Oct 27;21:1334-1336. doi: 10.1016/j.dib.2018.10.125. PMID: 30456254; PMCID: PMC6231039.
43: Casula M, Olmastroni E, Pirillo A, Catapano AL; MEMBERS OF THE LIPIGEN STEERING COMMETTEE; PRINCIPAL INVESTIGATORS: Coordinator center; Participant Centers; Participant Laboratories; COLLABORATORS; STUDY CENTRAL LABORATORY AND ANALYSIS GROUP. Evaluation of the performance of Dutch Lipid Clinic Network score in an Italian FH population: The LIPIGEN study. Atherosclerosis. 2018 Oct;277:413-418. doi: 10.1016/j.atherosclerosis.2018.08.013. PMID: 30270079.
44: Moulin P, Dufour R, Averna M, Arca M, Cefalù AB, Noto D, D'Erasmo L, Di Costanzo A, Marçais C, Alvarez-Sala Walther LA, Banach M, Borén J, Cramb R, Gouni-Berthold I, Hughes E, Johnson C, Pintó X, Reiner Ž, van Lennep JR, Soran H, Stefanutti C, Stroes E, Bruckert E. Identification and diagnosis of patients with familial chylomicronaemia syndrome (FCS): Expert panel recommendations and proposal of an "FCS score". Atherosclerosis. 2018 Aug;275:265-272. doi: 10.1016/j.atherosclerosis.2018.06.814. Epub 2018 Jun 18. PMID: 29980054.
45: Di Costanzo A, Belardinilli F, Bailetti D, Sponziello M, D'Erasmo L, Polimeni L, Baratta F, Pastori D, Ceci F, Montali A, Girelli G, De Masi B, Angeloni A, Giannini G, Del Ben M, Angelico F, Arca M. Evaluation of Polygenic Determinants of Non-Alcoholic Fatty Liver Disease (NAFLD) By a Candidate Genes Resequencing Strategy. Sci Rep. 2018 Feb 27;8(1):3702. doi: 10.1038/s41598-018-21939-0. PMID: 29487372; PMCID: PMC5829219.
46: Carpino G, Pastori D, Baratta F, Overi D, Labbadia G, Polimeni L, Di Costanzo A, Pannitteri G, Carnevale R, Del Ben M, Arca M, Violi F, Angelico F, Gaudio E. PNPLA3 variant and portal/periportal histological pattern in patients with biopsy-proven non-alcoholic fatty liver disease: a possible role for oxidative stress. Sci Rep. 2017 Nov 17;7(1):15756. doi: 10.1038/s41598-017-15943-z. PMID: 29150621; PMCID: PMC5693899.
47: Di Costanzo A, Di Leo E, Noto D, Cefalù AB, Minicocci I, Polito L, D'Erasmo L, Cantisani V, Spina R, Tarugi P, Averna M, Arca M. Clinical and biochemical characteristics of individuals with low cholesterol syndromes: A comparison between familial hypobetalipoproteinemia and familial combined hypolipidemia. J Clin Lipidol. 2017 Sep-Oct;11(5):1234-1242. doi: 10.1016/j.jacl.2017.06.013. Epub 2017 Jun 24. PMID: 28733173.
48: Gomaraschi M, Ossoli A, Castelnuovo S, Simonelli S, Pavanello C, Balzarotti G, Arca M, Di Costanzo A, Sampietro T, Vaudo G, Baldassarre D, Veglia F, Franceschini G, Calabresi L. Depletion in LpA-I:A-II particles enhances HDL- mediated endothelial protection in familial LCAT deficiency. J Lipid Res. 2017 May;58(5):994-1001. doi: 10.1194/jlr.P072371. Epub 2017 Mar 28. PMID: 28351888; PMCID: PMC5408617.
49: Minicocci I, Pozzessere S, Prisco C, Montali A, di Costanzo A, Martino E, Martino F, Arca M. Analysis of Children and Adolescents with Familial Hypercholesterolemia. J Pediatr. 2017 Apr;183:100-107.e3. doi: 10.1016/j.jpeds.2016.12.075. Epub 2017 Feb 1. PMID: 28161202.
50: Di Costanzo A, D'Erasmo L, Polimeni L, Baratta F, Coletta P, Di Martino M, Loffredo L, Perri L, Ceci F, Montali A, Girelli G, De Masi B, Angeloni A, Catalano C, Maranghi M, Del Ben M, Angelico F, Arca M. Non-alcoholic fatty liver disease and subclinical atherosclerosis: A comparison of metabolically- versus genetically-driven excess fat hepatic storage. Atherosclerosis. 2017 Feb;257:232-239. doi: 10.1016/j.atherosclerosis.2016.12.018. Epub 2016 Dec 21. PMID: 28027788.
51: Minicocci I, Tikka A, Poggiogalle E, Metso J, Montali A, Ceci F, Labbadia G, Fontana M, Di Costanzo A, Maranghi M, Rosano A, Ehnholm C, Donini LM, Jauhiainen M, Arca M. Effects of angiopoietin-like protein 3 deficiency on postprandial lipid and lipoprotein metabolism. J Lipid Res. 2016 Jun;57(6):1097-107. doi: 10.1194/jlr.P066183. Epub 2016 Apr 3. PMID: 27040449; PMCID: PMC4878193.
52: Minicocci I, Prisco C, Montali A, Di Costanzo A, Ceci F, Pigna G, Arca M. Contribution of mutations in low density lipoprotein receptor (LDLR) and lipoprotein lipase (LPL) genes to familial combined hyperlipidemia (FCHL): a reappraisal by using a resequencing approach. Atherosclerosis. 2015 Oct;242(2):618-24. doi: 10.1016/j.atherosclerosis.2015.06.036. Epub 2015 Jun 18. PMID: 26342331.

Finanziamenti
Bandi Ateneo Grant Sapienza 2020- Progetti Piccoli-Medi (prot. RM120172A3D02CB5)
Ruolo: Co-Investigatore
Bandi Ateneo Grant Sapienza 2017-Progetti Piccoli-Medi (prot.RM11715C683968EE)
Ruolo: Co-Investigatore
Bandi Ateneo Grant Sapienza 2016 Progetti Piccoli-Medi (prot. RM116154CA70843D)
Ruolo: Co-Investigatore
Presentazioni su Invito
2020 - Congresso Regionale SISA Lazio, Roma, Italia
I genotipi della Ipercolesterolemia Familiare: Implicazioni diagnostiche e cliniche .
2020 - Spring Meeting Giovani Ricercatori SIIA-SIMI-SISA 2020 - 2.0 itinerante.
Leggere e interpretare varianti genetiche, dal laboratorio alla clinica attraverso i lavori scientifici .
2019 - Giornata Mondiale sulla NASH. Roma, Italia.
Genetica della NAFLD .
2019 - Congresso Regionale SISA, Regione Lazio, Società Italiana Aterosclerosi.
NAFLD: vi e una predisposizione genetica?
2016 - Congresso Nazionale Di Medicina di Laboratorio (SIBIOC), Torino, Italia
Applicazioni delle Tecniche di Sequenziamento di Nuova Generazione allo studio dei disordini del Metabolismo Lipidico .
Premi e riconoscimenti
2018 - Premio Miglior presentazione poster 32° Congresso Nazionale Società Italiana di Aterosclerosi (SISA) Bologna, Italia
2017 - Premio Miglior comunicazione orale 31° Congresso Nazionale Società Italiana di Aterosclerosi (SISA) Palermo , Italia
Responsabilità scientifiche
2019 - 2021 Young Investigator Fellowship
Società Europea Aterosclerosi EAS
2019 - Certificato do Eccellenza in Lipidologia 2019 EAS Academy
Società Europea Aterosclerosi EAS
2014 - Advanced Course in human genetics of dyslipidemia
Società Europea Aterosclerosi EAS, Svezia
2012 - Advanced Course in Clinical Excellence in Cardiovascular Prevention and Lipidology
Società Europea Aterosclerosi EAS, Milano, Italia