Curriculum
PERSONAL INFORMATION
Name LIBONATI Laura
Address Department of Neurological Sciences, University of Rome “Sapienza”
Viale dell’Università 30, 00185 Rome, Italy
Telephone
E-mail laura.libonati@uniroma1.it
Nationality Italian
WORK EXPERIENCE
• Dates (from – to) From 01 Feb 2016 – to 31 Jul 2016
• Name and address of employer Department of Neurological Sciences, University of Rome “Sapienza”, Italy
• Type of business or sector
• Occupation or position held Winner of scholarship "Acquisition of epidemiological data and analysis of electrophysiological signals in patients suffering from amyotrophic lateral sclerosis"
• Dates (from – to) Aug 2016-Oct 2016
• Name and address of employer ASP AZIENDA SANITARIA LOCALE, Potenza
• Type of business or sector
• Occupation or position held
Emergency medical service
• Dates (from – to) From 01 Feb 2021 to 31 Jan 2023
• Name and address of employer Department of Neurological Sciences, University of Rome “Sapienza”
• Type of business or sector
• Occupation or position held Temporary research fellow
• Dates (from – to) From 01 Oct 2024 to nowadays
• Name and address of employer Department of Neurological Sciences, University of Rome “Sapienza”
• Type of business or sector
• Occupation or position held Researcher with a fixed-term contract of type A
• Main activities and responsibilities Clinical and research activity focused on Neuromuscular Rare Diseases
EDUCATION AND TRAINING
Dates (from-to) 2004-2009
• Name and type of organization providing education and training Liceo Scientifico Statale G. Galilei, Potenza
• Title of qualification awarded High school degree with a final judgment of 100/100 and praise
Dates (from-to) 2009-2015
• Name and type of organization providing education and training Faculty of Medicine and Dentistry, University of Rome La Sapienza
• Title of qualification awarded Degree in Medicine and Surgery with a final judgment of 100/100 and praise. Thesis title: “Dysphagia in ALS: neurological, biopsy and instrumental clinical study”.
Dates (from-to) 2013-2015
• Name and type of organisation providing education and training Course of excellence, Sapienza University of Rome, Faculty of Medicine and Dentistry,
• Title of qualification awarded Degree of course of excellence, Sapienza University of Rome
Dates (from-to) March - November 2018
• Name and type of organization providing education and training Advanced training course "Clinical electromyography", Sapienza University of Rome
• Principal subjects/occupational skills covered Electromyography and other methods of neurophysiology
• Title of qualification awarded Degree
Dates (from-to) From November 2016 to November 2020
• Name and type of organization providing education and training Residency in neurology, Department of Neurological Sciences, University of Rome “Sapienza”, Italy
• Principal subjects/occupational
•Title of qualification awarded
Neurology
Neurologist
Dates (from-to) From 12 Oct 2021 to 19 Jan 2021
• Name and type of organization providing education and training Advanced training course "EEG and evoked potentials", Sapienza University of Rome
• Principal subjects/occupational EEG and Evoked Potentials
Dates (from-to) From November 2020 to 09 Feb 2024
• Name and type of organization providing education and training
•Title of qualification awarded PhD student in Morphogenesis and tissue engineering, University of Rome “Sapienza”, Italy
PhD
MOTHER TONGUE ITALIAN
OTHER LANGUAGES
English
• Reading skills Good
• Writing skills Good
• Verbal skills Good
TECHNICAL SKILLS
AND COMPETENCES
With computers, specific kinds of equipment, machinery, etc. "I demonstrate good interpersonal skills with various healthcare professionals, ensuring effective collaboration and communication. My excellent organizational skills in both ward and outpatient activities reflect my commitment to coordinating resources and maintaining high service standards. Additionally, I possess advanced computer and software skills, which I successfully apply in managing and organizing research projects. These abilities enable me to produce high-quality scientific articles, integrating my experience in research project management and coordination."
ADDITIONAL INFORMATION Participation in clinical trials as Sub-Investigator:
- Study: Effects of Oral Levosimendan (ODM-109) on Respiratory Function in Patients With ALS
- Efficacy and Safety of Pozelimab and Cemdisiran Combination Therapy in Patients with Symptomatic Generalized Myasthenia Gravis. NIMBLE / R3918-MG-2018 Regeneron
- A phase 2, randomized, double-blind, placebo controlled, Parallel study to assess the efficacy,
Safety, tolerability, pk, and biomarker effects of PTC857 in adult subjects with amyotrophic lateral Sclerosis (CARDINALS)
08/06/2016 Winner of the PriSLA competition, for the awarding of Degree Prizes for thesis on the Amyotrophic lateral sclerosis.
PUBLICATIONS: 1. Vitamin D in amyotrophic lateral sclerosis. Libonati L, Onesti E, Gori MC, Ceccanti M, Cambieri C, Fabbri A, Frasca V, Inghilleri M. Funct Neurol. 2017 Jan/Mar;32(1):35-40.
2. Chronic inflammatory demyelinating polyneuropathy: evaluation of the vestibular system with cervical and ocular vestibular evoked myogenic potentials.Magliulo G, Iannella G, Manno A, Libonati L, Onesti E, Vestri A, Fegatelli DA, Angeletti D, Pace A, Gulotta G, Gagliardi S, Inghilleri M. Eur Arch Otorhinolaryngol. 2018 Jun;275(6):1507-1512.
3. Repetitive transcranial magnetic stimulation for chronic neuropathic pain in patients with bladder pain syndrome/interstitial cystitis. Cervigni M, Onesti E, Ceccanti M, Gori MC, Tartaglia G, Campagna G, Panico G, Vacca L, Cambieri C, Libonati L, Inghilleri M. Neurourol Urodyn. 2018 May 24. doi: 10.1002/nau.23718.
4. Short-Term Ultramicronized Palmitoylethanolamide Therapy in Patients with Myasthenia Gravis: a Pilot Study to Possible Future Implications of Treatment. Onesti E, Frasca V, Ceccanti M, Tartaglia G, Gori MC, Cambieri C, Libonati L, Palma E, Inghilleri M. CNS Neurol Disord Drug Targets. 2019 Jan 31. doi: 10.2174/1871527318666190131121827.
5. Heteronymous H reflex in temporal muscle as sign of hyperexcitability in ALS patients. Libonati L, Barone TF, Ceccanti M, Cambieri C, Tartaglia G, Onesti E, Petrucci A, Frasca V, Inghilleri M. Clin Neurophysiol. 2019 Aug;130(8):1455-1459. doi: 10.1016/j.clinph.2019.05.010. Epub 2019 May 22
6. A case of motor neuron involvement in Gaucher disease. Pozzilli V, Giona F, Ceccanti M, Cambieri C, Frasca V, Onesti E, Libonati L, Di Bari S, Fiorini I, Cardarelli L, Santopietro M, Inghilleri M. Mol Genet Metab Rep. 2019 Nov 12;21:100540. doi: 10.1016/j.ymgmr.2019.100540. eCollection 2019 Dec..
7. Creatine Kinase and Progression Rate in Amyotrophic Lateral Sclerosis. Ceccanti M, Pozzilli V, Cambieri C, Libonati L, Onesti E, Frasca V, Fiorini I, Petrucci A, Garibaldi M, Palma E, Bendotti C, Fabbrizio P, Trolese MC, Nardo G, Inghilleri M. Cells. 2020;9(5):E1174. Published 2020 May 8. doi:10.3390/cells9051174
8. A case of acute motor and sensory axonal neuropathy mimicking brain death. Libonati L, Fiorini I, Cambieri C, Ceccanti M, Inghilleri M. Neurol Sci. 2021 Jan 18. doi: 10.1007/s10072-021-05051-2. Epub ahead of print. PMID: 33459892.
9. Prevalence of amyotrophic lateral sclerosis in Latium region, Italy Puopolo M, Bacigalupo I, Piscopo P, Lacorte E, Di Pucchio A, Santarelli M, Inghilleri M, Petrucci A, Sabatelli M; Latium Registry Group; Vanacore N.. Brain Behav. 2021 Dec;11(12):e2378. doi: 10.1002/brb3.2378. Epub 2021 Oct 30. PMID: 34716673; PMCID: PMC8671775.
10. A novel homozygous mutation in TBK1 gene causing ALS-FTD. Neurol Sci. 2022 Jan 14. doi: 10.1007/s10072-021-05820-z. Epub ahead of print. PMID: 35028775.Libonati L, Ceccanti M, Cambieri C, Colavito D, Moret F, Fiorini I, Inghilleri M.
11. DYALS Study Group. Validation of the DYALS (dysphagia in amyotrophic lateral sclerosis) questionnaire for the evaluation of dysphagia in ALS patients. Diamanti L, Borrelli P, Dubbioso R, Capasso M, Morelli C, Lunetta C, Petrucci A, Mora G, Volanti P, Inghilleri M, Tremolizzo L, Mandrioli J, Mazzini L, Vedovello M, Siciliano G, Filosto M, Matà S, Montomoli C; Neurol Sci. 2022 May;43(5):3195-3200. doi: 10.1007/s10072-021-05775-1. Epub 2021 Dec 1. PMID: 34853898
12. Effects of Skin Stimulation on Sensory-Motor Networks Excitability: Possible Implications for Physical Training in Amyotrophic Lateral Sclerosis. Ceccanti M, Cambieri C, Libonati L, Tartaglia G, Moret F, Garibaldi M, Inghilleri M. Front Neurol. 2022 May 25;13:868792. doi: 10.3389/fneur.2022.868792. PMID: 35693021; PMCID: PMC9174685
13. Classical and Unexpected Effects of Ultra-Micronized PEA in Neuromuscular Function. Cifelli P, Ruffolo G, Ceccanti M, Cambieri C, Libonati L, Palma E, Inghilleri M. Biomolecules. 2022 May 29;12(6):758. doi: 10.3390/biom12060758. PMID: 35740883; PMCID: PMC9221058.
14. Effects of 3,4-diaminopyridine on myasthenia gravis: Preliminary results of an open-label study. Ceccanti M, Libonati L, Ruffolo G, Cifelli P, Moret F, Frasca V, Palma E, Inghilleri M, Cambieri Front Pharmacol. 2022 Aug 16;13:982434. doi: 10.3389/fphar.2022.982434. PMID: 36052140; PMCID: PMC9424766.
15. The Silent Period for Small Fiber Sensory Neuropathy Assessment in a Mixed Cohort of Transthyretin-Mediated Amyloidosis Cambieri C, Libonati L, Moret F, Tartaglia G, Garibaldi M, Chimenti C, Inghilleri M, Ceccanti M.. Biomedicines. 2022 Aug 24;10(9):2073. doi: 10.3390/biomedicines10092073. PMID: 36140174; PMCID: PMC9495326.
16. Effect of RNS60 in amyotrophic lateral sclerosis: a phase II multicentre, randomized, double-blind, placebo-controlled trial. Beghi E, Pupillo E, Bianchi E, Bonetto V, Luotti S, Pasetto L, Bendotti C, Tortarolo M, Sironi F, Camporeale L, Sherman AV, Paganoni S, Scognamiglio A, De Marchi F, Bongioanni P, Del Carratore R, Caponnetto C, Diamanti L, Martinelli D, Calvo A, Filosto M, Padovani A, Piccinelli SC, Ricci C, Dalla Giacoma S, De Angelis N, Inghilleri M, Spataro R, La Bella V, Logroscino G, Lunetta C, Tarlarini C, Mandrioli J, Martinelli I, Simonini C, Zucchi E, Monsurrò MR, Ricciardi D, Trojsi F, Riva N, Filippi M, Simone IL, Sorarù G, Spera C, Florio L, Messina S, Russo M, Siciliano G, Conte A, Saddi MV, Carboni N, Mazzini L; RNS60-ALS Study Group. Eur J Neurol. 2023 Jan;30(1):69-86. doi: 10.1111/ene.15573. Epub 2022 Oct 7. PMID: 36148821.
17. Does Patisiran Reduce Ocular Transthyretin Synthesis? A Pilot Study of Two Cases. Cambieri C, Marenco M, Colasanti T, Mancone C, Corsi A, Riminucci M, Libonati L, Moret F, Chimenti C, Lambiase A, Conti F, Garibaldi M, Inghilleri M, Ceccanti M. Curr Neuropharmacol. 2023 Jun 23. doi: 10.2174/1570159X21666230623094710. Epub ahead of print. PMID: 37357518.
18. Withdrawal of mechanical ventilation in amyotrophic lateral sclerosis patients: a multicenter Italian survey. Moglia C, Palumbo F, Veronese S; M. N. D. Italian Study Group; Calvo A. Neurol Sci. 2023 Jul 7. doi: 10.1007/s10072-023-06905-7. Epub ahead of print. PMID: 37418099.
19. Retrospective observational study on the use of acetyl-L-carnitine in ALS Sassi S, Bianchi E, Diamanti L, Tornabene D, Sette E, Medici D, Matà S, Leccese D, Sperti M, Martinelli I, Ghezzi A, Mandrioli J, Iuzzolino VV, Dubbioso R, Trojsi F, Passaniti C, D'Alvano G, Filosto M, Padovani A, Mazzini L, De Marchi F, Zinno L, Nuredini A, Bongioanni P, Dolciotti C, Canali E, Toschi G, Petrucci A, Perna A, Riso V, Inghilleri M, Libonati L, Cambieri C, Pupillo E.. J Neurol. 2023 Jun 28. doi: 10.1007/s00415-023-11844-6. Epub ahead of print. Erratum in: J Neurol. 2023 Sep 8;: PMID: 37378756.
20. Genetics screening in an Italian cohort of patients with Amyotrophic Lateral Sclerosis: the importance of early testing and its implication. Libonati L, Cambieri C, Colavito D, Moret F, D'Andrea E, Del Giudice E, Leon A, Inghilleri M, Ceccanti M. J Neurol. 2023 Dec 19. doi: 10.1007/s00415-023-12142-x. Epub ahead of print. PMID: 38112783.
21. MiR206 and 423-3p Are Differently Modulated in Fast and Slow-Progressing Amyotrophic Lateral Sclerosis Patients .Musarò, A., Dobrowolny, G., Cambieri, C. et al. Neuromol Med 26, 5 (2024). https://doi.org/10.1007/s12017-024-08773-6
22. Chronic inflammatory demyelinating polyneuropathy and HEV antibody status: A case-control study from Lazio, Italy Moret F, Spada E, Ceccanti M, Libonati L, D'Andrea E, Villano U, Madonna E, Chionne P, Carocci A, Pisani G, Fionda L, Antonini G, Petrucci A, Bruni R, Ciccaglione AR, Taliani G, Rivano Capparuccia M, Nobile-Orazio E, Inghilleri M, Cambieri C.. J Neurol Sci. 2024 Mar 12;459:122959. doi: 10.1016/j.jns.2024.122959. Epub ahead of print. PMID: 38490091.
23. Emotion recognition in amyotrophic lateral sclerosis in a dynamic environment. Ceccanti M, Libonati L, Moret F, D'Andrea E, Gori MC, Bersani FS, Inghilleri M, Cambieri C. J Neurol Sci. 2024 May 15;460:123019. doi: 10.1016/j.jns.2024.123019. Epub 2024 Apr 16. PMID: 38640582.
24. Oxidative Stress in Transthyretin-Mediated Amyloidosis: An Exploratory Study. Antioxidants (Basel) Fiore M, Cambieri C, Libonati L, Moret F, D'Andrea E, Di Certo MG, Passananti C, Gabanella F, Corbi N, Garibaldi M, Chimenti C, Alfarano M, Ferraguti G, Francati S, Inghilleri M, Ceccanti M. . 2024 Aug 18;13(8):998. doi: 10.3390/antiox13080998. PMID: 39199243; PMCID: PMC1135123
25. GDF15-GFRAL signaling drives weight loss and lipid metabolism in mouse model of amyotrophic lateral sclerosis Cocozza G, Busdraghi LM, Chece G, Menini A, Ceccanti M, Libonati L, Cambieri C, Fiorentino F, Rotili D, Scavizzi F, Raspa M, Aronica E, Inghilleri M, Garofalo S, Limatola C. Brain Behav Immun. 2024 Dec 11:S0889-1591(24)00739-6. doi: 10.1016/j.bbi.2024.12.010. Epub ahead of print. PMID: 39672239.
26. Assessment of upper GI motor activity and GI symptoms in patients with amyotrophic lateral sclerosis: an observational study Ribichini E, Pallotta N, Badiali D, Carlucci M, Ceccanti M, Cambieri C, Libonati L, Corazziari ES, Ruoppolo G and Inghilleri M (2025). Front. Neurol. 15:1509917. doi: 10.3389/fneur.2024.1509917
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