MARGHERITA EUFEMI

INIZIO LEZIONI BIOCHIMA (A-L) e (M-Z)

INIZIO LEZIONI DEL CORSO DI BIOCHIMICA (A-L), cod: 1008176, II anno C.T.F a.a 2020/2021.

LE LEZIONI DEL CORSO DI BIOCHIMICA A-L, INIZIERANNO MERCOLEDI’ 03 MARZO 2021 DALLE ORE 11.00 ALLE ORE 14.00 E PROSEGUIRANNO CON IL SEGUENTE ORARIO:

MARTEDI’                13.00-15.00

MERCOLEDI’           11.00-14.00

GIOVEDI’                 11.00-13.00

IN AULA B (AULETTE BLU PREFABBRICATE) EDIFICIO CU10, LIMITAMENTE AGLI STUDENTI PRENOTATI MEDIANTE LA PIATTAFORMA PRODIGIT.

GLI STUDENTI CHE SEGUONO DA REMOTO POSSONO COLLEGARSI MEDIANTE LA PIATTAFORMA MEET AL SEGUENTE LINK: https://meet.google.com/gfn-mrnd-ist

QUESTO LINK SARA’ VALIDO PER TUTTE LE LEZIONE E SI CONSIGLIA DI USARE COME BROWSER GOOGLE CHROME

INIZIO LEZIONI DEL CORSO DI BIOCHIMICA (M-Z) II anno C.T.F, cod: 1008176, a.a 2020/2021

LE LEZIONI DEL CORSO DI BIOCHIMICA M-Z, INIZIERANNO MERCOLEDI’ 03 MARZO 2021 DALLE ORE 15.00 ALLE ORE 17.00 E PROSEGUIRANNO CON IL SEGUENTE ORARIO:

MARTEDI’                11.00-13.00

MERCOLEDI’          15.00-17.00

GIOVEDI’                 13.00-16.00

IN AULA B (AULETTE BLU PREFABBRICATE) EDIFICIO CU10, LIMITAMENTE AGLI STUDENTI PRENOTATI MEDIANTE LA PIATTAFORMA PRODIGIT.

GLI STUDENTI CHE SEGUONO DA REMOTO POSSONO COLLEGARSI MEDIANTE LA PIATTAFORMA MEET AL SEGUENTE LINK: https://meet.google.com/rte-ogqn-phq

 QUESTO LINK SARA’ VALIDO PER TUTTE LE LEZIONE E SI CONSIGLIA DI USARE COME BROWSER GOOGLE CHROME.

PROF.SSA MARGHERITA EUFEMI

             RICEVIMENTO DEGLI STUDENTI E IL TUTORAGGIO A DISTANZA

PER AMBEDUE I CORSI (A-L) (M-Z) IL RICEVIMENTO DEGLI STUDENTI E IL TUTORAGGIO A DISTANZA SARÀ SVOLTO ATTRAVERSO, VIDEOCONFERENZA (GOOGLE MEET O SKYPE), PREVIO APPUNTAMENTO MEDIANTE MAIL.

Curriculum Vitae
Personal Information
Name and Surname: Margherita Eufemi
Department: Department of Biochemical Sciences
Address: P.le A. Moro 5 – 00185 Rome, Italy
Phone (Office/Lab/Mobile): +39 06 4991 0598
Email: margherita.eufemi@uniroma1.it
Scientific-Disciplinary Sector: BIOS-07A - Biochemistry
Current Position
Associate Professor- Department of Biochemical Sciences, Faculty of Pharmacy and Medicine -Sapienza University, Rome – Italy
Education and Academic Career
27/03/1985: Degree in Pharmacy – Sapienza University of Rome
19/05/1991: PhD in Biochemistry – Sapienza University of Rome
12/02/1992 - 31/12/2004: University Researcher – Sapienza University of Rome
From 01/01/2005: Associate Professor – Sapienza University of Rome
Teaching Activities
1. 1999–2001: Biochemistry (M–Z), 8 ECTS, Degree Course in Pharmacy – Sapienza University of Rome
2. 2002–2013: Biochemistry, 10 ECTS, Degree Course in Drug Information Science – Sapienza University of Rome
3. 2002–2003: Industrial Biochemistry (4 ECTS), Enzymology (4 ECTS), MSc in Pharmaceutical Biotechnology – Sapienza University of Rome
4. 2006–2007: Enzymology, 8 ECTS, Degree Course in Chemistry and Pharmaceutical Technology (CTF) – Sapienza University of Rome
5. 2007–2011: Biochemistry, 8 ECTS, Degree Course in CTF – Sapienza University of Rome
6. 2009–2013: Applied Biochemistry, 8 ECTS, Degree Course in CTF – Sapienza University of Rome
7. 2012–2013: Biochemical and Biotechnological Applications, Degree Course in CTF – Sapienza University of Rome
8. 2013–2018: Cellular and Functional Biochemistry, 3 ECTS, Degree Course in Pharmaceutical Biotechnology – Sapienza University of Rome
9. 2019: Cellular and Functional Biochemistry, 6 ECTS, Degree Course in Pharmaceutical Biotechnology – Sapienza University of Rome
10. 2020–2025: Cellular and Functional Biochemistry, 3 ECTS, Degree Course in Pharmaceutical Biotechnology – Sapienza University of Rome
11. 2011–2025: Biochemistry, 10 ECTS (A–L) (M–Z), Degree Course in CTF – Sapienza University of Rome
Research Activity
Cellular studies on the carcinogenic effects of environmental pollutants, particularly organochlorines, in both normal and tumor cells. Identification of natural compounds (e.g., lycopene, tyrosol, silybin, apigenin) as protective agents against pollutant-induced carcinogenesis, with potential applications in green therapy for populations living in polluted areas. Research activities also involve collaborations with various research groups, primarily focusing on the functional analysis of the STAT3 protein, its post-translational modifications (PTMs), and molecular interactors, in response to different signaling pathways and cancer-related processes. Studies include signal transduction pathways mediated by STAT3 in tumor cells, the role of STAT3 PTMs in carcinogenesis, and their involvement in key phenotypes and histological types of prostate and breast cancer. Characterization of STAT3–ERp57 specific macromolecular complexes. In vitro and in vivo analysis of protein–protein and protein–DNA interactions.

Participation in national and international conferences.
Personal Skills And Competences:
Biochemistry techniques: eukaryotic cell cultures, proteins extraction, purification and characterization and electrophoretic analysis of protein. Immunological techniques (Western Blot, immunoprecipitation, immunofluorescence). Cellular assays: cell clonogenic, wound healing and migration, comet, apoptosis and cell cycle analysis by flow cytometry.
Molecular biology techniques: DNA purification and electrophoretic analysis- PCR and real time techniques – Luciferase assay.

Awards and Recognitions
• 1987: Cenci Bolognetti – Pasteur Institute Foundation Award
• 1995: Young Researcher Award
• 2017: Rocca D’Oro Award
• 2019: Luisa Minazzi 'Environmental Activist of the Year' Award

Professional Memberships And Other Activities
• Membership: SIB
• Editor: Biomedicine MPDI
Bibliometric Data (March 2025)

ORCID ID: 0000-0001-9153-972X

(SCOPUS database)
Pubblicazioni totali: 68
Citazioni totali: 1543
H-index:23

Publications
1. Thiol proteins in chromatin. A.Ferraro, A.Giartosio, M.Eufemi, D.Barra, F.Altieri, C.Turano. Bioscience Reportes 6, 257-263 (1986).
2. Non-histone proteins in trascriptionally active chromatin. M.Eufemi, A.Ferraro, F.Altieri, G.Spoto, C.Turano. Bas. Appl. Histochem. 31, 239- 246 (1987).
3. Calorimetric analysis of sodium dodecylsulfate-chromatin interaction. A.Giartosio, A.Ferraro, F.Altieri, M.Eufemi, C.Turano. Physiol. Chem. Physics and Med. NMR 20, 55-60 (1988).
4. Non-histone chromatin proteins from mammalian tissues. F.Altieri, A.Ferraro, M.Eufemi, G.Spoto, C.Turano. in "Macromolecules in the functioning cell", (5th Sov. Ital. symp. A.Castellani, C. Balduini, P.Volpe eds., CNR) pp. 125-130 (1988).
5. Glycoproteins distribution in non-histone chromatin proteins from pig liver. A.Ferraro, L.Antonilli, M.D'Erme, M.Eufemi, M.A.Rosei, G. Spoto. Ital. J. Biochem. 37, 213-218 (1988).
6. Tissue specificity of chromatin glycoproteins recognized by Concanavalin A. A.Ferraro, M.Eufemi, F.Altieri, C.Turano. Biochem. International 18, 405-414 (1989).
7. Interaction of chromatin glycoproteins with DNA. M.Eufemi, A.Ferraro, L.Cervoni, C.Turano. Ital. J. Biochem. 38, 281-283 (1989).
8. Glycosylated forms of nuclear lamins. A.Ferraro, M.Eufemi, L.Cervoni, C.Turano. FEBS Letters 257, 241-246 (1989).
9. 3'-5' cAMP phosphodiesterase in pig liver nuclei. G.Lupidi, M.Eufemi, S.Luciani, A.Ferraro, F.Riva. Ital. J. Biochem. 39, 30-37 (1990).
10. Fucose-carryng nuclear glycoproteins: distribution and tissue specificity. L.Cervoni, A.Ferraro, M.Eufemi, C.Turano. Ital. J. Biochem. 39, 368-374 (1990).
11. Glycoproteins from mammalian chromatin. A.Ferraro, M.Eufemi, L Cervoni, C.Turano. in " Macromolecules in the functioning cell ", (6th Sov. Ital. symp. A.Castellani, C.Balduini and P.Volpe eds. CNR),pp 91-105 (1991).
12. Nuclear glycoproteins in higher vertebrates. M.Eufemi, F.Altieri, L.Cervoni, G.Spoto, A.Ferraro. Biochem. International 23, 35-42 (1991).
13. The presence of N-glycosylated proteins in cell nuclei. A.Ferraro, P.Grandi, M.Eufemi, F.Altieri, L.Cervoni, C.Turano. Biochem. Biophys. Res. Comm. 178, 1365-1370, (1991).
14. Differential scanning calorometry of chicken erytrocyte nuclei. A.Giartosio, C.Wang, S.D'Alessio, A.Ferraro, F.Altieri, M.Eufemi, C.Turano. Eur. J. Biochem. 208, 17-22, (1992).
15. Macromolecular interactions in the nuclear scaffold. F.Altieri, P.Grandi, V.Di Cioccio, M.Eufemi, A.Ferraro, C.Turano. Italian Journal of Biochemistry 41, 132-133, (1992).
16. Crosslinking of nuclear proteins to DNA by cis-diamminedichloroplatinum in intact cells. A.Ferraro, P.Grandi, M.Eufemi, F.Altieri, C.Turano. FEBS Letters 307, 383-385, (1992).
17. Isolation of a novel nuclear glycoprotein from pig kidney. M.Eufemi, B.Maras, S.Valiante, F.Altieri, G.Spoto, C.Turano, A.Ferraro. Biochemistry International 27, 1001-1009,(1992).
18. N-glycosylated nuclear glycoproteins. A.Ferraro, F.Altieri, L.Cervoni, M.Eufemi, P.Grandi, G.Spoto, C.Turano. in "Macromolecules in the functioning cell" (P. Volpe, A. Cambria and S. Macaione eds.) pp 35-43, Pacini Editore, Pisa,(1993).
19. Purification of a 57kDa nuclear matrix protein associated with thiol: protein-disulfide oxidoreductase and phospholipase C activities. F.Altieri, B.Maras, M.Eufemi, A.Ferraro, C.Turano. Biochem. Biophys. Res. Commun. 178, 992-1000, (1993).
20. Glycoproteins of the nuclear matrix from chicken liver cells. A.Ferraro, M.Eufemi, F.Altieri, L.Cervoni, C.Turano. Cell Biology International 18, 655-661, (1994).
21. Specific nuclear protein-carbohydrate interaction in chicken hepatocytes. M.Eufemi, A.Mazzon, C.Turano, A.Ferraro. Ital. J. Biochem. 43,93A-95A, (1994).
22. Specific recognition sites for oligosaccharides in avian liver nuclei. M.Eufemi, C.Turano, F.Altieri, A.Ferraro. Biochem. Molecular Biol. Internat. 34, 475-481, (1994).
23. Glycosylated Subunits in Wheat Germ RNA Polymerase II. L.Cervoni, M.Eufemi, L.Capponi, A.Ferraro, C.Turano, A.Giartosio. in "Wheat Kernel Proteins" (Università degli Studi della Tuscia-CNR eds) pp. 335-337, (1994).
24. DNA-nuclear matrix interactions analyzed by cross-linking reactions in intact nuclei from avian liver. A.Ferraro, M.Eufemi, L.Cervoni, F.Altieri, C.Turano. Acta Biochimica Polonica 42, 145-152 (1995).
25. Protein-DNA interactions at the nuclear scaffold attachment regions of DNA loops. A.Ferraro, M.Eufemi, L.Cervoni, F.Altieri, C.Turano. Physiological Chemestry and Physics and Medical NMR 27, 313-320, (1995).
26. A comparison of DNA-protein interactions in intact nuclei from avian and erythrocytes: a cross-linking study. A.Ferraro, L.Cervoni, M.Eufemi, F.Altieri, C. Turano. Journal of Cellular Biochemistry 61, 1-11, (1996).
27. The influence of the carbohydrate moiety on the stability of glycoproteins. C.Q.Wang, M.Eufemi, C.Turano, A.Giartosio. Biochemestry 35, 7299-7307, (1996).
28. Glycosylation of RNA polymerase II from wheat germ. L.Cervoni, C.Turano, A.Ferraro, P.Ciavatta, F.Marmocchi, M.Eufemi. FEBS Letters 417, 227-230, (1997).
29. Nuclear matrix localization of chicken hsp 108. F.Altieri, M.Eufemi, B.Maras, C.Turano. Cellular and Molecular Biology Letters 2, 439-448, (1997).
30. Differentiation-specific nuclear matrix proteins cross-linked to DNA by cis-diammine dichloroplatinum. E.Mattia, M.Eufemi, S.Chichiarelli, M.Ceridono, A.,Ferraro. Exp. Cell Res. 238, 216-219, (1998).
31. Binding of the protein disulfide isomerase isoform Erp60 to the nuclear matrix-associated regions of DNA. A. Ferraro, F.Altieri, S. Coppari, M. Eufemi, S. Chicchiarelli, C.Turano. Journal of Cellular Biochemestry 72, 528-539, (1999).
32. Cross-linked telomere-protein complexes from chicken erythrocyte nuclei: isolation by a new procedure. L. Cervoni, A. Ferraro, M. Eufemi, F. Altieri, S. Chichiarelli, C. Turano. Biochem. Biophys. Res. Commun. 254, 517-521, (1999).
33. DNA-Protein cross-linking in nuclei of immature and mature chicken erythrocytes. M. Eufemi, A. Ferraro, F. Altieri, L. Cervoni, C. Turano. Molecular Biology Reports 27, 181-189, (2000).
34. Immunoprecipitation of DNA-protein complexes cross-linked by cis-diamminedichloroplatinum. Chichiarelli S, Coppari S, Turano C, Eufemi M, Altieri A, Ferraro A. Anal Biochem. 302, 224-9, (2002).
35. Nuclear localization and DNA interaction of protein disulfide isomerase ERp57 in mammalian cells. Coppari S, Altieri A, Ferraro A, Chicchiarelli S, Eufemi M, Turano C.. Journal of Cellular Biochemestry.. 85, 325-33, (2002)
36. Chromosome-protein interactions in polyomavirus virions. Carbone M, Ascione G, Chichiarelli S, Garcia MI, Eufemi M, Amati P. J Virol. 78, 513-9, (2004)
37. ERp57 is present in STAT3-DNA complexes. Eufemi M, Coppari S, Altieri F, Grillo C, Ferraro A, Turano. Biochem Biophys Res Commun. 323, 1306-12 (2004)
38. DNA sequences acting as binding sites for NM23/NDPK proteins in melanoma M14 cells. Cervoni L, Egistelli L, Eufemi M, d'Abusco AS, Altieri F, Lascu I, Turano C, Giartosio A. J Cell Biochem. 98, 421-8, (2006).
39. Effect of infliximab on the glycosylation of IgG of patients with rheumatoid arthritis. Croce A, Firuzi O, Altieri F, Eufemi M, Agostino R, Priori R, Bombardieri M, Alessandri C, Valesini G, Saso L. J Clin Lab Anal. 21, 303-14, (2007)
40. The stress protein ERp57/GRP58 binds specific DNA sequences in HeLa cells. Chichiarelli S, Ferraro A, Altieri F, Eufemi M, Coppari S, Grillo C, Arcangeli V, Turano C. J Cell Physiol. 210, 343-51, (2007)
41. DNA-binding activity of the ERp57 C-terminal domain is related to a redox-dependent conformational change. Grillo C, D'Ambrosio C, Consalvi V, Chiaraluce R, Scaloni A, Maceroni M, Eufemi M, Altieri F. J Biol Chem. 282, 10299-310, (2007)
42. The binding of antibiotics to ERp57/GRP58. Gaucci E, Chichiarelli S, Grillo C, Vecchio ED, Eufemi M, Turano C. J Antibiot (Tokyo). 2008 Jun;61(6):400-2.
43. IFI16 and NM23 bind to a common DNA fragment both in the P53 and the cMYC gene promoters. Egistelli L, Chichiarelli S, Gaucci E, Eufemi M, Schininà ME, Giorgi A, Lascu I, Turano C, Giartosio A, Cervoni L. J Cell Biochem. 2009 Mar 1;106(4):666-72.
44. Role of ERp57 in the signaling and transcriptional activity of STAT3 in a melanoma cell line. Chichiarelli S, Gaucci E, Ferraro A, Grillo C, Altieri F, Cocchiola R, Arcangeli V, Turano C, Eufemi M. Arch Biochem Biophys. 2010 Feb15;494(2):178-83.
45. ERp57/PDIA3 binds specific DNA fragments in a melanoma cell line. Aureli C, Gaucci E, Arcangeli V, Grillo C, Eufemi M, Chichiarelli S. Gene. 2013 Jul 25;524(2):390-5.
46. Upregulation of TPX2 by STAT3: identification of a novel STAT3 binding site. Cocchiola R, Grillo C, Altieri F, Chichiarelli S, Turano C, Eufemi M. PLoS One. 2014 Nov 17;9(11):e113096
47. Acetylation and phosphorylation of STAT3 are involved in the responsiveness of microglia to beta amyloid. Eufemi M, Cocchiola R, Romaniello D, Correani V, Di Francesco L, Fabrizi C, Maras B, Schininà ME. Neurochem Int. 2015 Feb;81:48-56
48. Analysis of the interaction of calcitriol with the disulfide isomerase ERp57.Gaucci E, Raimondo D, Grillo C, Cervoni L, Altieri F, Nittari G, Eufemi M, Chichiarelli S. Sci Rep. 2016 Nov 29;6:37957
49. Comparative Analysis of the Interaction between Different Flavonoids and PDIA3.Giamogante F, Marrocco I, Romaniello D, Eufemi M, Chichiarelli S, Altieri F.Oxid Med Cell Longev. 2016;2016:4518281
50. Analysis of STAT3 post-translational modifications (PTMs) in human prostate cancer with different Gleason Score. Cocchiola R, Romaniello D, Grillo C, Altieri F, Liberti M, Magliocca FM, Chichiarelli S, Marrocco I, Borgoni G, Perugia G, Eufemi M. Oncotarget. 2017 Jun 27;8(26):42560-42570.
51. Caryophyllane sesquiterpenes inhibit DNA-damage by tobacco smoke in bacterial and mammalian cells. Di Giacomo S, Abete L, Cocchiola R, Mazzanti G, Eufemi M, Di Sotto A. Food Chem Toxicol. 2018 Jan;111:393-404
52. Punicalagin, an active pomegranate component, is a new inhibitor of PDIA3 reductase activity. Giamogante F, Marrocco I, Cervoni L, Eufemi M, Chichiarelli S, Altieri F. Biochimie. 2018 Apr;147:122-129.
53. STAT3, a Hub Protein of Cellular Signaling Pathways, Is Triggered by β-Hexaclorocyclohexane. Rubini E, Altieri F, Chichiarelli S, Giamogante F, Carissimi S, Paglia G, Macone A, Eufemi M. Int J Mol Sci. 2018 Jul 20;19(7). pii: E2108.
54. The induction of Maspin expression by a glucosamine-derivative has an antiproliferative activity in prostate cancer cell lines. Cocchiola R, Lopreiato M, Guazzo R, de Santi MM, Eufemi M, Scandurra R, Scotto d'Abusco A. Chem Biol Interact. 2019 Feb 25;300:63-72.
55. STAT3 Post-Translational Modifications Drive Cellular Signaling Pathways in Prostate Cancer Cells. Cocchiola R, Rubini E, Altieri F, Chichiarelli S, Paglia G, Romaniello D, Carissimi S, Giorgi A, Giamogante F, Macone A, Perugia G, Gurtner A, Eufemi M. Int J Mol Sci. 2019 Apr 12;20(8). pii: E1815.
56. Hypoglycemic, Antiglycation, and Cytoprotective Properties of a Phenol-Rich Extract From Waste Peel of Punica granatum L. var. Dente di Cavallo DC2. Di Sotto A, Locatelli M, Macone A, Toniolo C, Cesa S, Carradori S, Eufemi M, Mazzanti G, Di Giacomo S. Molecules. 2019 Aug 27;24(17):3103
57. Shmt2: A Stat3 Signaling New Player in Prostate Cancer Energy Metabolism.Marrocco I, Altieri F, Rubini E, Paglia G, Chichiarelli S, Giamogante F, Macone A, Perugia G, Magliocca FM, Gurtner A, Maras B, Ragno R, Patsilinakos A, Manganaro R, Eufemi M. Cells. 2019 Sep 6;8(9):1048
58. Potentiation of Low-Dose Doxorubicin Cytotoxicity by Affecting P-Glycoprotein through Caryophyllane Sesquiterpenes in HepG2 Cells: an in Vitro and in Silico Study.Di Sotto A, Irannejad H, Eufemi M, Mancinelli R, Abete L, Mammola CL, Altieri F, Mazzanti G, Di Giacomo S. Int J Mol Sci. 2020 Jan 17;21(2):633.
59. Modulation of STAT3 Signaling, Cell Redox Defenses and Cell Cycle Checkpoints by β-Caryophyllene in Cholangiocarcinoma Cells: Possible Mechanisms Accounting for Doxorubicin Chemosensitization and Chemoprevention. Di Sotto A, Di Giacomo S, Rubini E, Macone A, Gulli M, Mammola CL, Eufemi M, Mancinelli R, Mazzanti G. Cells. 2020 Apr 2;9(4):858.
60. Chemopreventive Potential of Caryophyllane Sesquiterpenes: An Overview of Preliminary Evidence.Di Sotto A, Mancinelli R, Gullì M, Eufemi M, Mammola CL, Mazzanti G, Di Giacomo S. Cancers (Basel). 2020 Oct 18;12(10):3034.
61. β-Hexachlorocyclohexane: A Small Molecule with a Big Impact on Human Cellular Biochemistry.Rubini E, Paglia G, Cannella D, Macone A, Di Sotto A, Gullì M, Altieri F, Eufemi M, Biomedicines. 2020 Nov 16;8(11):505.
62. Tomato and Olive Bioactive Compounds: A Natural Shield against the Cellular Effects Induced by β-Hexachlorocyclohexane-Activated Signaling Pathways. Rubini E, Minacori M, Paglia G, Macone A, Chichiarelli S, Altieri F, Eufemi M.Molecules. 2021 Nov 25;26(23):7135. doi:10.3390/molecules26237135.
63. β-Hexachlorocyclohexane Drives Carcinogenesis in the Human Normal Bronchial Epithelium Cell Line BEAS-2B.Rubini E, Minacori M, Paglia G, Altieri F, Chichiarelli S, Romaniello D, Eufemi M. Int J Mol Sci. 2021 May 29;22(11):5834.
64. Improving Whole Tomato Transformation for Prostate Health: Benign Prostate Hypertrophy as an Exploratory Model. Natali PG, Piantelli M, Minacori M, Eufemi M, Imberti L.Int J Mol Sci. 2023 Mar 17;24(6):5795. doi: 10.3390/ijms24065795
65. β-Caryophyllene Counteracts Chemoresistance Induced by Cigarette Smoke in Triple-Negative Breast Cancer MDA-MB-468 Cells. Di Sotto A, Gullì M, Minacori M, Mancinelli R, Garzoli S, Percaccio E, Incocciati A, Romaniello D, Mazzanti G, Eufemi M, Di Giacomo S.Biomedicines. 2022 Sep 12;10(9):2257. doi: 10.3390/biomedicines10092257
66. Ribosome-Directed Therapies in Cancer. Temaj G, Chichiarelli S, Eufemi M, Altieri F, Hadziselimovic R, Farooqi AA, Yaylim I, Saso L.Biomedicines. 2022 Aug 26;10(9):2088. doi: 10.3390/biomedicines10092088
67. Sorafenib Chemosensitization by Caryophyllane Sesquiterpenes in Liver, Biliary, and Pancreatic Cancer Cells: The Role of STAT3/ABC Transporter Axis. Di Giacomo S, Gullì M, Facchinetti R, Minacori M, Mancinelli R, Percaccio E, Scuderi C, Eufemi M, Di Sotto A.Pharmaceutics. 2022 Jun 14;14(6):1264. doi: 10.3390/pharmaceutics14061264.
68. Ascorbate as a Bioactive Compound in Cancer Therapy: The Old Classic Strikes Back. González-Montero J, Chichiarelli S, Eufemi M, Altieri F, Saso L, Rodrigo R.Molecules. 2022 Jun 14;27(12):3818 doi: 10.3390/molecules27123818.
69. ERp57/PDIA3: new insight. Chichiarelli S, Altieri F, Paglia G, Rubini E, Minacori M, Eufemi M.Cell Mol Biol Lett. 2022 Feb 2;27(1):12. doi: 10.1186/s11658-022-00315-x.
70. Protein Disulfide Isomerase A3 (PDIA3): A Pharmacological Target in Glioblastoma?Paglia G, Minacori M, Meschiari G, Fiorini S, Chichiarelli S, Eufemi M, Altieri F. Int J Mol Sci. 2023 Aug 26;24(17):13279. doi: 10.3390/ijms241713279.
71. STAT3 Pathways Contribute to β-HCH Interference with Anticancer Tyrosine Kinase Inhibitors.Fiorini S, Rubini E, Perugini M, Altieri F, Chichiarelli S, Meschiari G, Arrighetti G, Vijgen J, Natali PG, Minacori M, Eufemi M. Int J Mol Sci. 2024 Jun 4;25(11):6181. doi: 10.3390/ijms25116181.
72. Analysis of Punicalin and Punicalagin Interaction with PDIA3 and PDIA1.Meschiari G, Minacori M, Fiorini S, Tedesco M,Eufemi M, Altieri F. Int J Mol Sci. 2024 Sep 30;25(19):10531. doi: 10.3390/ijms251910531.
73. A step forward in enhancing the health-promoting properties of whole tomato as a functional food to lower the impact of non-communicable diseases.Natali PG, Piantelli M, Sottini A, Eufemi M, Banfi C, Imberti L..Front Nutr. 2025 Feb 5;12:1519905. doi: 10.3389/fnut.2025.1519905. eCollection 2025.
74. AhR and STAT3: A Dangerous Duo in Chemical Carcinogenesis Minacori M, Fiorini S, Perugini M, Iannetta A, Meschiari G, Chichiarelli S, Altieri F, Natali PG, Eufemi M. Int J Mol Sci. 2025 Mar 18;26(6):2744. doi: 10.3390/ijms26062744.