Ritratto di gianluca.canettieri@uniroma1.it

Nato a Viterbo, Gianluca Canettieri si è laureato in Medicina e Chirurgia nel 1995 presso l’Università “La Sapienza” di Roma, dove ha poi svolto il dottorato di ricerca in Endocrinologia e Malattie metaboliche.

 

È stato visiting fellow presso la Johns Hopkins University di Baltimora (1996) e, successivamente, post doctoral fellow presso il Salk Institute for Biological Studies di San Diego (2000-2005), acquisendo competenze nell’ambito delle alterazioni trascrizionali ed epigenetiche legate allo sviluppo di malattie metaboliche, tumorali e genetiche.

 

È tornato in Italia nel 2005 grazie al programma ministeriale “Rientro dei Cervelli”, entrando nel 2008 nel ruolo universitario di professore associato.

Dal 2019 è professore ordinario di patologia generale presso l’Università “La Sapienza” di Roma.

E' membro del Collegio dei Docenti del Dottorato in Medicina Molecolare.

Dirige l’Unità di Epigenetica, Metabolismo e Cancro del Dipartimento di Medicina Molecolare.

Fa parte del Comitato Tecnico-Scientifico AIRC.

È tesoriere della Società Italiana di Patologia e Medicina Traslazionale (SIPMeT).

È Vicepresidente del collegio dei professori ordinari del SSD Med/04.

È stato Chair delle Gordon Research Conferences (GRC) on Polyamines, Waterville Valley NH, USA nel 2023.

 


Oltre agli interessi in ambito oncologico, i suoi studi sono focalizzati su patologie genetiche e dismetaboliche.

Insegnamento Codice Anno Corso - Frequentare Bacheca
PATHOLOGY AND PATHOPHYSIOLOGY 1048214 2023/2024
BASI FISIOPATOLOGICHE DELLE MALATTIE 10589388 2023/2024
PATOLOGIA GENETICA E GENETICA UMANA - BIOTECNOLOGIE DELLA RIPRODUZIONE UMANA 10596058 2023/2024
PATOLOGIA GENETICA E GENETICA UMANA - BIOTECNOLOGIE DELLA RIPRODUZIONE UMANA 10596058 2022/2023
BASI FISIOPATOLOGICHE DELLE MALATTIE 10589388 2022/2023
PATHOLOGY AND PATHOPHYSIOLOGY 1048214 2022/2023
BASI FISIOPATOLOGICHE DELLE MALATTIE 10589388 2021/2022
PATHOLOGY AND PATHOPHYSIOLOGY 1048214 2021/2022
PATOLOGIA GENETICA E GENETICA UMANA - BIOTECNOLOGIE DELLA RIPRODUZIONE UMANA 10596058 2021/2022
BASI FISIOPATOLOGICHE DELLE MALATTIE 10589388 2021/2022
PATHOLOGY AND PATHOPHYSIOLOGY 1048214 2021/2022
BASI FISIOPATOLOGICHE DELLE MALATTIE 10589388 2020/2021
PATOLOGIA GENETICA E GENETICA UMANA - BIOTECNOLOGIE DELLA RIPRODUZIONE UMANA 1044567 2020/2021
PATHOLOGY AND PATHOPHYSIOLOGY 1048214 2020/2021
PATHOLOGY AND PATHOPHYSIOLOGY 1048214 2020/2021
BASI FISIOPATOLOGICHE DELLE MALATTIE 10589388 2019/2020
PATHOLOGY AND PATHOPHYSIOLOGY 1048214 2019/2020
PATOLOGIA GENETICA E GENETICA UMANA - BIOTECNOLOGIE DELLA RIPRODUZIONE UMANA 1044567 2019/2020
BASI FISIOPATOLOGICHE DELLE MALATTIE 10589388 2018/2019
PATOLOGIA GENETICA E GENETICA UMANA - BIOTECNOLOGIE DELLA RIPRODUZIONE UMANA 1044567 2018/2019
PATHOLOGY AND PATHOPHYSIOLOGY 1048214 2018/2019
BASI FISIOPATOLOGICHE DELLE MALATTIE 1045141 2017/2018
PATOLOGIA GENETICA E GENETICA UMANA - BIOTECNOLOGIE DELLA RIPRODUZIONE UMANA 1044567 2017/2018
PATHOLOGY AND PATHOPHYSIOLOGY 1048214 2017/2018
PER LA CONOSCENZA DI ALMENO UNA LINGUA STRANIERA AAF1186 2016/2017
BASI FISIOPATOLOGICHE DELLE MALATTIE 1045141 2016/2017
PATHOLOGY AND PHYSIOPATHOLOGY 1038247 2016/2017
PATOLOGIA GENETICA E GENETICA UMANA - BIOTECNOLOGIE DELLA RIPRODUZIONE UMANA 1044567 2016/2017

Per appuntamento concordato mediante recapiti istituzionali

PERSONAL INFORMATION

Name Gianluca Canettieri
Address Viale Regina Elena 291, Rome, Italy
Telephone 06-49255130 Mobile
SCOPUS links
Other link https://www.scopus.com/authid/detail.uri?authorId=6603196887
https://web.uniroma1.it/mog/g-canettieri

E-mail Gianluca.canettieri@uniroma1.it

WORK EXPERIENCE

Dates (from - to) 2019 - present
Name and address of the employer Department of Molecular Medicine, La Sapienza University of Rome, Italy;
Type of business or sector Education/scientific Research
Occupation or position held Full Professor of General Pathology, MED/04
Main activities and responsibilities

Dates (from - to) 2012- Present
Name and address of the employer University of Rome La Sapienza, Department of Molecular Medicine
Type of business or sector Scientific Research
Occupation or position held Head of Epigenetic, Metabolism and Cancer Unit

Main activities and responsibilities Direct and coordinates the scientific research of the laboratory

Dates (from - to) 2020-Present
Name and address of the employer University of Rome La Sapienza, Department of Experimental Medicine
Type of business or sector Scientific Research
Occupation or position held Member of the Executive Committee of the Research and Services Centre for Preclinical Experimentation and Animal Welfare (SPBA), Sapienza University of Rome

Main activities and responsibilities

Dates (from - to) 2008- 2019
Name and address of the employer: University of Rome La Sapienza, Department of Molecular Medicine
Type of business or sector: Education/scientific Research
Occupation or position held: Associate Professor of General Pathology; MED/04;
Main activities and responsibilities

Dates (from - to) 2005 - 2008
Name and address of the employer University of Rome La Sapienza, Department of Experimental Medicine
Type of business or sector Scientific Research
Occupation or position held Assistant Professor (Professore a Contratto) of General Pathology MED/04 Programma Rientro dei Cervelli - MIUR - University of Rome La Sapienza

Main activities and responsibilities

Dates (from - to) 2000-2005
Name and address of the employer Salk Institute for Biological Studies, Peptide Biology laboratories, La Jolla, CA, USA
Type of business or sector Scientific Research
Occupation or position held Research Associate/postdoctoral fellow

Dates (from - to) 2006
Name and address of the employer Johns Hopkins University, Baltimore MD USA, Geriatric Division
Type of business or sector Scientific Research
Occupation or position held Visiting fellow

EDUCATION AND TRAINING

Dates (from - to) 2000
Name and type of organisation providing education and training Sapienza University of Rome. PhD program in Endocrinology and Molecular Medicine
Title of qualification awarded PhD degree in Endocrinology and Molecular Medicine

Dates (from - to) 1996
Name and type of organisation providing education and training Sapienza University of Rome
Title of qualification awarded Board certification for medical practice

Dates (from - to) 1995
Name and type of organisation providing education and training Sapienza University of Rome
Title of qualification awarded Medical Doctor degree, Summa cum laude

PERSONAL SKILLS AND COMPETENCES
MOTHER TONGUE Italian
OTHER LANGUAGES ENGLISH

SCIENTIFIC SKILLS AND COMPETENCES
Metabolic reprogramming in tumors sustained by alterations of developmental pathways (Hedgehog, WNT): medulloblastoma, colorectal cancer. Energy and redox balance, bioenergetics, polyamine metabolism, nutrition and cancer. Studies in animal and preclinical models, drug discovery. Transcriptional and translational alterations operating in tumors, metabolic and endocrine disorders.

COLLABORATIONS

International:
Salk Institure for Biological Studies, La Jolla, CA; The Burnham Institute, La Jolla, CA; Scripps Research institute, San Diego, CA; The Genomics Institute of the Novartis Research Foundation, San Diego, CA University of Ottawa, Canada; University of Toronto, Canada, University of Florida, FL; Harvard Medical School, Boston, MA, Whitehead Institute for Biomedical Research, Cambridge, MA; University of Illinois College of Medicine, Chicago, IL; Osaka University, Osaka, Japan; Johns Hopkins University, Baltimore, MD, University of Maryland, Baltimore, MD; University of Warzav, Poland; École Polytechnique Fédérale de Lausanne, Switzerland, University of Leeds, UK

National:
Università di Palermo; Università di Bari; Università di Pisa, Università di Messina; Università di Siena, Università di Roma Tor Vergata; Università Cattolica del Sacro Cuore, Roma; Consiglio Nazionale delle Ricerche, Roma e Napoli, Italian Institute of Tecnology, Rome, Consorzio Mario Negri Sud, Santa Maria Imbaro, Chieti, Cancer Genetics Laboratory, IRCCS S. de Bellis, Castellana Grotte; IRBM-Merck Research Laboratories Rome; Ente Per Le Nuove Technologie, l'Energia e l'Ambiente (ENEA), Centro Ricerche Casaccia, Casaccia, Roma; Neuromed Institute Pozzilli, Isernia; Istituto Nazionale della Nutrizione, Roma

RELEVANT ROLES AND COMPETENCES
Coordination and administration of people, projects and budgets. Coordinator/PI and administrator of the following funded projects:

-2005-2008: Grant MIUR progetto Rientro dei Cervelli .
Title: Meccanismi molecolari coinvolti nell oncogenesi molecolare.

-2008: Sapienza University Funding per acquisizione di medie e grandi attrezzature scientifiche .
Title: Applicazioni post-genomiche nella medicina molecolare: studio integrato delle modificazioni genetiche ed epigenetiche nella patogenesi tumorale. Grandi Attrezzature Scientifiche .

-2008: Sapienza University Funding Ateneo Federato di Scienza delle politiche pubbliche e sanitarie SPPS.
Title: Patogenesi molecolare dei tumori cerebellari: identificazione di ZNF9 come nuovo co-repressore della pathway di Hedgehog .

-2009: Sapienza University Funding Ateneo Federato di Scienza delle politiche pubbliche e sanitarie SPPS (Rinnovo).
Title: Patogenesi molecolare dei tumori cerebellari: identificazione di ZNF9 come nuovo co-repressore della pathway di Hedgehog .

-2009-2011: Grant MIUR (PRIN). Responsabile Scientifico di Unità.
Title: Ruolo della famiglia di coattivatori CRTC nella funzione endoteliale e nell'aterosclerosi

-2010-2015: Project Coordinator MIUR FIRB, accordi di programma. micro-RNA: dai meccanismi alle applicazioni diagnostiche e terapeutiche.

-2011: Sapienza University Funding.
Title: Ruolo del controllo traduzionale nello sviluppo e nel differenziamento nervoso regolato dalla via di Hedgehog .

-2011: Sapienza University Funding FARI
Title: Studio della trasformazione metabolica nei tumori del sistema nervoso.

-2014 Sapienza University Funding.
Title: Regolazione del metabolismo delle poliamine da parte della via di Hedgehog: meccanismo molecolare e ruolo nel medulloblastoma

-2015-2017: Sapienza University Funding (Progetti Grandi)
Title: CNBP-cMyc axis in colorectal carcinogenesis

-2016-2020: Grant AIRC: IG # 17575.
Title: Pro-tumorigenic role of the CNBP-cMyc axis in colorectal carcinogenesis

-2018-2020: Pasteur Institute Anna Tramontano Research Grant
Title: Targeting MYC translation in Colorectal Cancer

-2019-2021: Sapienza University Funding. Title: Role of IRES-dependent translation of MYC in Colorectal Cancer

-2020-2022: Sapienza University Funding for Conferences and workshop for Gordon Research Conference (GRC) on Polyamines: Polyamines in Cancer, Medical Genetics, Aging, Microbiome and Plants.

-2022-2026: Grant AIRC IG 25833.
Title: Targeting energy and redox alterations in colorectal cancer.

-2022-2024: Pasteur Institute Anna Tramontano Research Grant
Title: Targeting Redox State in Colorectal Cancer

-2022-2024: Grant University Funding (Progetti Grandi)
Title: Targeting Reductive Stress-GDF15 Axis in Colorectal Cancer

-2023-2025: Grant Telethon GMR22T1027
Title: Understanding the role of CNBP-eIF5A-polyamine metabolism in DM2 pathogenesis

International Grants

-2002-2003: Career Development Award, Juvenile Diabetes Research Foundation (JDRF, USA)
-2017-2021: AFM-Telethon (France). Title: Analysis of the DM2 pathogenic mechanisms using Drosophila as model system

Other Appointments:

-2023: Member of the Scientific-Technical Committee (CTS) of the Italian Cancer Research Foundation (AIRC)
-2022: Secretary of the Executive Board of the College of Full Professors SSD Med/04
-2020-Present: Secretary-Treasurer of the Italian Society of Pathology and Translational Medicine (SIPMeT)
-2021 Member of the Scientific Committee of the SIPMeT Young Scientist Meeting MOLECULAR PATHOLOGY: FROM BENCH TO BEDSIDE Perugia, December 10th 11th, 2021
-2015-Present Member of the Italian Society of Pathology and Translational Medicine (SIPMeT)
-1997-Present: member of the Italian Society of Endocrinology (SIE)
-2008- Date: Faculty member of the PhD program in Molecular Medicine, Sapienza University of Rome.
-2019-Present: Member of the International Polyamine Foundation
-2021-Present: member of the European Nutrition and Cancer Research (NACRe) network

Honors

-1998: Best oral presentation award - XVI Giornate Italiane della Tiroide (GIT). Rome 3-5 December 1998.
-2005: Best poster presentation award XXXI meeting of the Italian Society of Endocrinology (SIE) - Genova, Italy 4-7 May.
-2000-2001: Istituto Pasteur - Cenci-Bolognetti Foundation fellowship award for research abroad.
-2000-2001: Postdoctoral training fellowship Salk Institute for Biological Studies
-2005: Istituto Pasteur - Fondazione Cenci-Bolognetti award
-2002-2003: Career Development Award, Juvenile Diabetes Research Foundation (JDRF, USA)
-2005-2008: Progetto Rientro dei Cervelli award - MIUR, Italy.

Conference Lecturer:
-2002: Invited speaker, National Academy of Science (Accademia Nazionale dei Lincei) International Symposium, Roma 5-6 aprile).
-2005: Invited speaker, 13th International Thyroid Congress, Buenos Aires, Argentina. October 30 - November 4
-2006 Invited Speaker, European Thyroid association meeting, Sep 2-6
-2007 Invited Speaker VII Meeting of Molecular Oncology, May 14-17 Positano, Italy
-2009: Invited speaker, IRE Annual Workshop On Chromatin Remodeling And Human Disease Rome, December 3/4 2009
-2013: Invited speaker Epigenetic Rome Training School, Rome
-2014: Invited speaker University of L Aquila, Italy
-2015: Invited speaker 38th Meeting Italian Society of Endocrinology SIE Taormina 27-30 May
-2016: Invited speaker, 4th International Conference on Polyamines September 2016 Rome (Tivoli) ITALY
-2017: Invited speaker Polyamines Gordon Research Conference, Waterville Valley, NH USA June
-2017: Invited speaker, University of Salzburg, Austria November 2017
-2018: Invited speaker Montminy Celebration Symposium Salk Institute for Biological Studies, San Diego, CA USA August 2018
-2017: Vice Chair Polyamines Gordon Research Conference, Waterville Valley, NH USA June 2017
-2020: Invited speaker, International Winter School of Molecular Medicine, Rome December 2021
-2021: Invited speaker, Association for Molecular Pathology (AMP) Europe virtual Meeting, Milan
-2021: Invited Speaker First NACRe European Seminar, Paris, France November 2021

Conference organization and chair
-2019-2023 Chair of the Gordon Research Conference (GRC) on Polyamines: Polyamines in Cancer, Medical Genetics, Aging, Microbiome and Plants June 25-30/2023 Waterville Valley, NH, USA
-2017-2019: Vice-Chair of Gordon Research Conference (GRC) on Polyamines: Polyamines in Cancer Biology, Inflammation, Microbiome, Plants and Pathogens June 23-28/2019 Waterville Valley, NH, USA
-2021: Session Chair, SIPMET Meeting, Perugia, Italy - December 2021
-2022, Organizer, Invited Speaker and Chair of the 6 th International Conference on Polyamines Biochemical Physiological and Clinical Perspectives September 4-9, 2022 Tivoli-Rome
-2022, Organizer, Invited Speaker and Chair of the 25th International Symposium on Molecular Medicine September 4-9, 2022 Tivoli-Rome
-2022 Member of the Scientific Committee of the SIPMeT Young Scientist Meeting PATHOPHYSIOLOGY OF DISEASE Ancona, September 22nd 24th, 2022

PUBLICATIONS
Total number of publications in peer-review journals (Pubmed): 83
Total Impact Factor (publication year) 930; average IF/paper: 11,21
Total number of citations: 5250 (WOS)
H index: 37 (Scholar); 34 (Scopus)
ASN (Commissario) requisites: YES 3/3

All Pubications: https://pubmed.ncbi.nlm.nih.gov/?term=canettieri+g&sort=date

Most relevant 20 publications:

Canettieri G, Di Marcotullio L, Greco A, Coni S, Antonucci L, Infante P, Pietrosanti L, De Smaele E, Ferretti E, Miele E, Pelloni M, De Simone G, Pedone EM, Gallinari P, Giorgi A, Steinkühler C, Vitagliano L, Pedone C, Schinin ME, Screpanti I, Gulino A. Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation.
Nat Cell Biol. 2010 Feb;12(2):132-42.
IF:20.06

Canettieri G, Koo SH, Berdeaux R, Heredia J, Hedrick S, Zhang X, Montminy M. Dual role of the coactivator TORC2 in modulating hepatic glucose output and insulin signaling.
Cell Metab. 2005 Nov;2(5):331-8.
IF:18.164

D'Amico D, Antonucci L, Di Magno L, Coni S, Sdruscia G, Macone A, Miele E, Infante P, Di Marcotullio L, De Smaele E, Ferretti E, Ciapponi L, Giangaspero F, Yates JR 3rd, Agostinelli E, Cardinali B, Screpanti I, Gulino A, Canettieri G.
Non-canonical Hedgehog/AMPK-Mediated Control of Polyamine Metabolism Supports Neuronal and Medulloblastoma Cell Growth.
Dev Cell. 2015 Oct 12;35(1):21-35. doi: 10.1016/j.devcel.2015.09.008.
IF:9.174

Di Magno L, Manni S, Di Pastena F, Coni S, Macone A, Cairoli S, Sambucci M, Infante P, Moretti M, Petroni M, Nicoletti C, Capalbo C, De Smaele E, Di Marcotullio L, Giannini G, Battistini L, Goffredo BM, Iorio E, Agostinelli E, Maroder M, Canettieri G.
Phenformin Inhibits Hedgehog-Dependent Tumor Growth through a Complex I-Independent Redox/Corepressor Module.
Cell Rep. 2020 Feb 11;30(6):1735-1752.e7. doi: 10.1016/j.celrep.2020.01.024.
IF: 9.42

Canettieri G, Morantte I, Guzman E, Asahara H, Herzig S, Anderson SD, Yates JR 3rd, Montminy M.
Attenuation of a phosphorylation-dependent activator by an HDAC-PP1 complex.
Nat Struct Biol. 2003 Mar;10(3):175-81.
IF:11.579

Canettieri G*, Coni S, Della Guardia M, Nocerino V, Antonucci L, Di Magno L, Screaton R, Screpanti I, Giannini G, Gulino A.
The coactivator CRTC1 promotes cell proliferation and transformation via AP-1.
Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1445-50.
*Corresponding Author
IF:9.661

Screaton RA, Conkright MD, Katoh Y, Best JL, Canettieri G, Jeffries S, Guzman E, Niessen S, Yates JR 3rd, Takemori H, Okamoto M, Montminy M.
The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector.
Cell. 2004 Oct 1;119(1):61-74.
IF:30.41

Conkright MD, Canettieri G, Screaton R, Guzman E, Miraglia L, Hogenesch JB, Montminy M.
TORCs: transducers of regulated CREB activity.
Mol Cell. 2003 Aug;12(2):413-23.
IF:14.714

Jhala US, Canettieri G, Screaton RA, Kulkarni RN, Krajewski S, Reed J, Walker J, Lin X, White M, Montminy M.
cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2.
Genes Dev. 2003 Jul 1;17(13):1575-80.
IF:9.413

Bufalieri F, Infante P, Bernardi F, Caimano M, Romania P, Moretti M, Lospinoso Severini L, Talbot J, Melaiu O, Tanori M, Di Magno L, Bellavia D, Capalbo C, Puget S, De Smaele E, Canettieri G, Guardavaccaro D, Busino L, Peschiaroli A, Pazzaglia S, Giannini G, Melino G, Locatelli F, Gulino A, Ayrault O, Fruci D, Di Marcotullio L.
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of TrCP.
Nat Commun. 2019 Jul 24;10(1):3304. doi: 10.1038/s41467-019-11093-0.
IF: 12.121

Infante P, Faedda R, Bernardi F, Bufalieri F, Lospinoso Severini L, Alfonsi R, Mazzà D, Siler M, Coni S, Po A, Petroni M, Ferretti E, Mori M, De Smaele E, Canettieri G, Capalbo C, Maroder M, Screpanti I, Kool M, Pfister SM, Guardavaccaro D, Gulino A, Di Marcotullio L.
Itch/ -arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis.
Nat Commun. 2018 Mar 7;9(1):976. doi: 10.1038/s41467-018-03339-0.
IF:12.124

Centanni M, Gargano L, Canettieri G, Viceconti N, Franchi A, Delle Fave G, Annibale B.
Thyroxine in goiter, Helicobacter pylori infection, and chronic gastritis.
N Engl J Med. 2006 Apr 27;354(17):1787-95.
IF:72.406

D'Amico D, Canettieri G.
Translating Hedgehog in Cancer: Controlling Protein Synthesis.
Trends Mol Med. 2016 Oct;22(10):851-862. doi: 10.1016/j.molmed.2016.08.003. Review.
IF: 10.732

Coni S, Falconio FA, Marzullo M, Munafò M, Zuliani B, Mosti F, Fatica A, Ianniello Z, Bordone R, Macone A, Agostinelli E, Perna A, Matkovic T, Sigrist S, Silvestri G, Canettieri G*, Ciapponi L*.
Translational control of polyamine metabolism by CNBP is required for Drosophila locomotor function.
Elife. 2021 Sep 14;10:e69269. doi: 10.7554/eLife.69269. PMID: 34517941 Free PMC article. * Co-senior and corresponding author
IF: 8.1

Coni S, Serrao SM, Yurtsever ZN, Di Magno L, Bordone R, Bertani C, Licursi V, Ianniello Z, Infante P, Moretti M, Petroni M, Guerrieri F, Fatica A, Macone A, De Smaele E, Di Marcotullio L, Giannini G, Maroder M, Agostinelli E, Canettieri G
Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation.
Cell Death Dis. 2020 Dec 10;11(12):1045. doi: 10.1038/s41419-020-03174-
IF: 8.4

Infante P, Mori M, Alfonsi R, Ghirga F, Aiello F, Toscano S, Ingallina C, Siler M, Cucchi D, Po A, Miele E, D'Amico D, Canettieri G, De Smaele E, Ferretti E, Screpanti I, Uccello Barretta G, Botta M, Botta B, Gulino A, Di Marcotullio L.
Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors.
EMBO J. 2015 Jan 13;34(2):200-17. doi: 10.15252/embj.201489213. Epub 2014 Dec 4.
IF:9.792

Garg N, Po A, Miele E, Campese AF, Begalli F, Silvano M, Infante P, Capalbo C, De Smaele E, Canettieri G, Di Marcotullio L, Screpanti I, Ferretti E, Gulino A.
microRNA-17-92 cluster is a direct Nanog target and controls neural stem cell through Trp53inp1.
EMBO J. 2013 Oct 30;32(21):2819-32. doi: 10.1038/emboj.2013.214. Epub 2013 Sep 27.
IF:9.792

Po A, Ferretti E, Miele E, De Smaele E, Paganelli A, Canettieri G, Coni S, Di Marcotullio L, Biffoni M, Massimi L, Di Rocco C, Screpanti I, Gulino A.
Hedgehog controls neural stem cells through p53-independent regulation of Nanog.
EMBO J. 2010 Aug 4;29(15):2646-58.
IF:9.792

Zhang X, Odom DT, Koo SH, Conkright MD, Canettieri G, Best J, Chen H, Jenner R, Herbolsheimer E, Jacobsen E, Kadam S, Ecker JR, Emerson B, Hogenesch JB, Unterman T, Young RA, Montminy M.
Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues.
Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4459-64.
IF:9.661

Mayr BM, Canettieri G, Montminy MR.
Distinct effects of cAMP and mitogenic signals on CREB-binding protein recruitment impart specificity to target gene activation via CREB.
Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10936-41.
IF:9.661

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